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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Towards A Better Performance for Medical Image Retrieval Using An Integrated Approach</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Zheng Ye</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Xiangji Huang</string-name>
          <email>jhuangg@yorku.ca</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Hongfei Lin</string-name>
          <email>hflin@dlut.edu.cn</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>General Terms</string-name>
        </contrib>
        <contrib contrib-type="editor">
          <string-name>Measurement, Performance, Experimentation</string-name>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Information Retrieval Lab, Dalian University of Technology</institution>
          ,
          <addr-line>Dalian</addr-line>
          ,
          <country country="CN">China</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Information Retrieval and Knowledge Managment Lab, York University</institution>
          ,
          <addr-line>Toronto</addr-line>
          ,
          <country country="CA">Canada</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>In this paper, we propose an integrated approach for medical image retrieval. In particular, we present a series of experiments in medical image retrieval task. There are three main goals for our participation of this task. First, we will test traditional well-known weighting models used in text retrieval domain, such as BM25, TFIDF and Language Model (LM), for context-based image retrieval. Second, we will evaluate statistical-based feedback models and ontology-based feedback models. Third, we will investigate how content-based image retrieval can be integrated with these two basic technologies of traditional text retrieval. The experimental results have shown that 1) traditional weighting models can work well in context-based medical image retrieval task especially when the parameters are tuned properly; 2) statistical-based feedback models can improve the retrieval performance when a small number of documents are used; however, the medical image retrieval can not benefit from ontology-based query expansion; 3) the retrieval performance can be slightly boosted by integrating content features.</p>
      </abstract>
      <kwd-group>
        <kwd>H</kwd>
        <kwd>3 [Information Storage and Retrieval]</kwd>
        <kwd>H</kwd>
        <kwd>3</kwd>
        <kwd>1 Content Analysis and Indexing</kwd>
        <kwd>H</kwd>
        <kwd>3</kwd>
        <kwd>3 Information Search and Retrieval</kwd>
        <kwd>H</kwd>
        <kwd>3</kwd>
        <kwd>4 Systems and Software</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>For the first year of the participation in ImageCLEFmed task, we first test traditional
wellknown weighting models used in text retrieval domain, such as BM25, TFIDF and LM, for
contextbased image retrieval. Since the text context information (captions) is very short, which is different
from traditional adhoc text collections, it is necessary to test and adapt traditional weighting
models for this particular task. Second, on the basis of the baseline results, we use
statisticalbased pseudo relevance feedback and ontology-based (MeSH 1) query expansion approaches to
enhance the retrieval performance. Finally, we note that many images share the same context
text for comparison reason in an article, but the circumstance is always that only one of these
images is what we are looking for. So it is impossible for us to filter other images with the same
context text using only the context-based image retrieval technologies. We explore different image
content features to enhance context-based image retrieval technologies.</p>
      <p>The remainder of this paper is organized as follows. In section 2, we describe the comparisons
of basic retrieval models. In section 3, we present the experimental results for statistical-based
and ontology-based query expansion. In section 4, we propose an integrated approach for medical
image retrieval. In section 5, we conclude the paper with a discussion of our findings and a look
at future work.
2</p>
    </sec>
    <sec id="sec-2">
      <title>Weighting Models</title>
      <p>In the previous medical image retrieval tasks, a number of different information retrieval (IR)
toolkits, such as Lemur, Jirs and Lucene, are used as the basic retrieval systems for context-based
medical image retrieval. However, there is no systematic comparison of different weighting models
for ImageCLEFmed task. In addition, it is not clear that whether the default parameters in these
models empirically tuned for traditional adhoc datasets are optimal.</p>
      <p>
        In this paper, we have made comparisons for four well-known weighting models: BM25 [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ], JM
- LM [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ], TFIDF and DFR In expB2 [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]. The corresponding weighting functions are as follows.
      </p>
      <p>BM25
JM - LM
TFIDF
DFR
! =
k1 ((1
(k1 + 1) tf
b) + b dl=avdl) + tf
log</p>
      <p>N</p>
      <p>n + 0:5
n + 0:5
(k3 + 1 ) qtf</p>
      <p>k3 + qtf
! = (1 +
1
tf</p>
      <p>F reqT otColl
l Ft</p>
      <p>)
! = qtf</p>
      <p>k1 tf
tf + k1 (1
b + b
dl )
avdl
log(1 +</p>
      <p>N
n</p>
      <p>)
! = T F
qtf</p>
      <p>N ORM</p>
      <p>N + 1
loge( n exp )</p>
      <p>T F = tf log2(1 + avdl=dl)
N ORM = (tf + 1)=(df (T F + 1))
n exp = idf (1</p>
      <p>e f )
f = qtf =df
(1)
(2)
(3)
(4)
where w is the weight of a query term, N is the number of indexed documents in the collection,
n is the number of documents containing the term, R is the number of documents known to
be relevant to a specific topic, r is the number of relevant documents containing the term, tf
is within-document term frequency, qtf is within-query term frequency, dl is the length of the
document, avdl is the average document length, nq is the number of query terms, the kis are
tuning constants (which depend on the database and possibly on the nature of the queries and
are empirically determined), K equals to k1 ((1 b) + b dl=avdl).</p>
      <p>In our experiments, the values of k1, k2, k3 and b in the BM25 function are set to be 1.2, 0,
8 and 0.75 respectively; the value of is set to 0.15. In addition, the image context texts are
preprocessed in the same way for all experiments in order to make reasonable comparison. We use
blank delimiter to separate words for indexing and searching and stopwords are removed. Beside
these two simple steps, no further technologies have been used.</p>
    </sec>
    <sec id="sec-3">
      <title>Query Expansion</title>
      <sec id="sec-3-1">
        <title>Query expansion with the Bose-Einstein distribution</title>
        <p>
          The pseudo relevance feedback method used in our experiments is DFR-based weighting model
described in [
          <xref ref-type="bibr" rid="ref2">2</xref>
          ]. The basic idea of these term weighting models for query expansion is to measure
the divergence of a term’s distribution in a pseudo relevance set from its distribution in the whole
collection. The higher this divergence is, the more likely the term is related to the query topic.
We use Bo1 weighting model in this set of experiments. The Bo1 term weighting model is based
on the Bose-Einstein statistics. Using this model, the weight of a term t in the exp doc top-ranked
documents is given by:
where exp doc usually ranges from 3 to 10 [
          <xref ref-type="bibr" rid="ref2">2</xref>
          ]. Another parameter involved in the query expansion
mechanism is exp term, the number of terms extracted from the exp doc top-ranked documents.
exp term is usually larger than exp doc [
          <xref ref-type="bibr" rid="ref2">2</xref>
          ]. Pn is given by NF , F is the frequency of the term in
the collection, and N is the number of documents in the collection. tfx is the frequency of the
query term in the exp doc top-ranked documents.
        </p>
        <p>The main goal of this set of experiments is to investigate how many top documents and terms
should be used for query expansion. For the limitation of space, we only present experimental
results on the basis of BM25 model.</p>
        <p>Form table 5 we can see, in general, the performance can be boosted if we can set the
parameters properly. When the number of documents for query expansion increases from 5 to 10,
the performance drops quickly. The results in table 5 suggests that only a very small number
documents are useful for query expansion in context-based medical image retrieval task.
3.2</p>
      </sec>
      <sec id="sec-3-2">
        <title>Query Expansion with MeSH Ontology</title>
        <p>In medical domain, terms are highly synonymous and ambiguous. This motivates us to investigate
using ontology to expand the original query terms.</p>
        <p>The Medical Subject Headings (MeSH) is a thesaurus developed by the National Library of
Medicine. MeSH contains two organization files, an alphabetic list with bags of synonymous and
related terms, and a hierarchical organization of descriptors associated to the terms. A term is
composed by one or more words.</p>
        <p>We have used the longest match approach to recognize the MeSH terms in a query. In
particular, if all the words of a term are in the query, we add our synonymous terms to the query.
To compare the words of a particular term and those of the query, we rst put all the words in
lowercase and we do not remove stop words. In order to reduce the number of terms that could
expand the query, only three categories of MeSH terms (A: Anatomy, C: Diseases, E:
Analytical, Diagnostic and Therapeutic Techniques and Equipment) have been used for query expansion.
Table 3.2 presents the MeSH-based query expansion results under four different models.</p>
        <p>Unfortunately, MeSH-based query expansion approach does not work well as we expected.
Our conjecture is that MeSH-based query expansion may also bring negative terms into query,
especially the abbreviation terms. In addition, when the JM-LM is used as the basic retrieval
model, the performance drops remarkably. This is another evidence that the performance of
JM-LM is not steady.
4</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>An Integrated Approach</title>
      <p>Content-based Image Retrieval (CBIR) systems enable users to search a large image database by
issuing an image sample, in which the actual contents of the image will be analyzed. The contents
of an image refer to its features – colors, shapes, textures, or any other information that can be
derived from the image itself. This kind of technology sounds interesting and promising. The key
issue in CBIR is to extract representative features to describe an image. However, this is a very
very difficult research topic.</p>
      <p>
        According to ImageCLEFmed conference notes [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ], CBIR always performs poorly , while
context based image retrieval can always achieve good performance in terms of MAP measurement.
However, content features are also needed, especially when context information is not easy to
obtain or a number of images share the same context. This motivates us to combine these two
technologies and give a relatively lower weight to CBIR approaches. In particular, we explore
three representative features for medical image retrieval.
      </p>
      <p>
        1. Color and Edge Directivity Descriptor (CEDD): is a low level feature which
incorporates color and texture information in a histogram [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ].
2. Tamura Histogram Descriptor: features coarseness, contrast, directionality,
linelikeness, regularity, and roughness. The relative brightness of pairs of pixels is computed
such that degree of contrast, regularity, coarseness and directionality may be estimated [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ].
3. Color Histogram Descriptor: Retrieving images based on color similarity is achieved by
computing a color histogram for each image that identifies the proportion of pixels within an
image holding specific values (that humans express as colors). Current research is attempting
to segment color proportion by region and by spatial relationship among several color regions.
Examining images based on the colors they contain is one of the most widely used techniques
because it does not depend on image size or orientation.
      </p>
      <p>The final rank list is attained by merging the context-based retrieved score (Scontext) and
content-based similarity score (Scontent). In particular, we use linear combination. The formula is
described as follows.</p>
      <p>score = (1
) Scontext +</p>
      <p>Scontent
(6)</p>
      <p>From table 7, we can see that retrieval performance can be slightly boosted by integrating
content features. Among these three features, CEDD can improve the performance most. However,
more representative features are needed to be developed.
In this study, we first evaluate four well-known weighting models for context based medical image
retrieval. The performances of the four weighting models are comparable, but DFR weighting
model works best under default settings. JM-LM model is not steady for this task, but if the
parameter can be tuned properly, it is still promising. Second, we investigate query expansion
technologies for this task. In general, statistical-based QE method outperforms ontology-based
methods. The experimental results also suggests that only a small number of top ranked documents
are useful for statistical-based QE method. Ontology-based methods sound interesting and useful,
however the actual performance is not good. More sophisticated processing for this kind of methods
is needed. Finally, we explore three content features for content-based medical image retrieval.
The experimental results have shown that retrieval performance can only be slightly improved.
The current features extracted from images may not be representative enough to capture the
characteristics of images. Better features are required to improve CBIR.</p>
      <p>In the future work, we will work on the following two directions. First, we will use data-driven
approaches to choose optimal parameters for statistical-based QE. Second, we will explore the
correlation of different content features of images. In addition, if more features can be integrated
into medical image retrieval properly, we believe the retrieval performance can be further improved.
6</p>
    </sec>
    <sec id="sec-5">
      <title>Acknowledgements</title>
      <p>This research is jointly supported by NSERC of Canada, the Early Researcher/Premier’s Research
Excellence Award, Natural Science Foundation of China (No. 60373095 and 60673039) and the
National High Tech Research and Development Plan of China (2006AA01Z151).</p>
    </sec>
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