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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>The medGIFT Group in ImageCLEFmed 2013</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Alba G. Seco de Herrera</string-name>
          <email>alba.garcia@hevs.ch</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Dimitrios Markonis</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Roger Schaer</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Ivan Eggel</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Henning Mu¨ller</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>SO) Sierre</institution>
          ,
          <country country="CH">Switzerland</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>University of Applied Sciences Western Switzerland (HES</institution>
        </aff>
      </contrib-group>
      <abstract>
        <p>This article presents the participation of the medGIFT group in ImageCLEFmed 2013. Since 2004, the group has participated in the medical image retrieval tasks of ImageCLEF each year. There are four types of tasks for ImageCLEFmed 2013: modality classi cation, image{ based retrieval, case{based retrieval and a new task on compound gure separation. The medGIFT group participated in all four tasks. MedGIFT is developing a system named ParaDISE (Parallel Distributed Image Search Engine), which is the successor of GIFT (GNU Image Finding Tool). The alpha version of ParaDISE was used to run the experiments in the competition. The focus was on the use of multiple features in combinations with novel strategies, i.e, compound gure separation for modality classi cation or modality ltering for ad{hoc image and case{ based retrieval.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>Introduction</title>
      <p>
        ImageCLEF [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] is the cross–language image retrieval track1 of the Cross
Language Evaluation Forum (CLEF). ImageCLEFmed has been focusing on
medical image retrieval since 2004 [
        <xref ref-type="bibr" rid="ref10 ref11 ref2 ref3 ref4 ref5 ref6 ref7 ref8 ref9">2–11</xref>
        ]. In 2013, the medical task consisted of four
subtasks including modality classification, compound figure separation, ad–hoc
image–based retrieval and case–based retrieval [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ]. A large database containing
over 300,000 images from the biomedical literature was used for the tasks.
      </p>
      <p>
        This article describes the participation of the medGIFT2 research group in
ImageCLEFmed 2013. The medGIFT group has participated in ImageCLEFmed
since 2004 and is currently developing ParaDISE (Parallel Distributed Image
Search Engine), which is the successor of GIFT3 (GNU Image Finding Tool)
that was used for many years as the baseline in ImageCLEF. As in 2012 [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ],
the alpha version of ParaDISE was used to run the experiments. In 2013, there
are four main novelties in the submitted runs:
{ a combination of multiple visual features was used;
{ semantic information was included;
      </p>
      <sec id="sec-1-1">
        <title>1 http://www.imageclef.org/ 2 http://medgift.hevs.ch/ 3 http://www.gnu.org/software/gift/</title>
        <p>{ modality filtering was used for image– and case–based retrieval;
{ compound figure detection was performed.</p>
        <p>A combination of these strategies was used for the run submissions. For the
modality classification task, the best medGIFT submission achieved a
classification accuracy of 69.63% and was ranked in the fourth position. In its first year,
the compound figure separation task only attracted three groups. MedGIFT
achieved the best results, which could be expected since the data had been used
by the group and the ground truth was created ahead of time. In the ad–hod
image and case–based retrieval, the medGIFT group was ranked second for the
visual and mixed submissions. The text runs submitted acquired average results
with a simple Lucene baseline.</p>
        <p>The rest of the paper is organized as following. In Section 2, the datasets and
the techniques used are described. The runs submitted to the ImageCLEFmed
2013 benchmark are described and evaluated in Section 3. Finally, conclusions
are presented in Section 4.
2</p>
      </sec>
    </sec>
    <sec id="sec-2">
      <title>Datasets and Techniques</title>
      <p>
        This section describes the basic techniques used in ImageCLEFmed 2013 by the
medGIFT group. More detail on the setup of ImageCLEFmed 2013 can be found
in [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ].
      </p>
      <p>Ten runs (three textual, three visual and four mixed) were submitted to the
image–based retrieval task, five runs (one textual, three visual and one mixed) to
the case–based retrieval task, ten runs (one textual, four visual and five mixed)
to the modality classification task and two visual runs to the compound figure
separation task.</p>
      <sec id="sec-2-1">
        <title>2.1 Image Collection</title>
        <p>
          The database provided for ImageCLEFmed 2013 [
          <xref ref-type="bibr" rid="ref11">11</xref>
          ] contains over 300,000
images of 75,000 articles of the biomedical open access literature. It is a subset of
PubMed Central4 containing over 1.5 million images. The distributed PubMed
subset contains only articles allowing redistribution.
2.2
        </p>
      </sec>
      <sec id="sec-2-2">
        <title>Textual Techniques</title>
        <p>For text retrieval, the Apache Lucene framework was used. The built–in text
analyser class named EnglishAnalyzer was used to apply lowercasing, stopword
removal and stemming in their standard settings. The full text and the captions
were indexed separately as the text to use depends on the exact goal of the
search.</p>
        <p>
          For modality classification, a step was included where a classifier using the
Radlex ontology described in [
          <xref ref-type="bibr" rid="ref13">13</xref>
          ] was used for semantic consistency checking of
        </p>
        <sec id="sec-2-2-1">
          <title>4 http://www.ncbi.nlm.nih.gov/pmc/</title>
          <p>images classified as containing radiology modalities. A mistake prevented this
from being used in the submitted runs. Post–submission experiments show that
the inclusion of semantics can improve the results.
2.3</p>
        </sec>
      </sec>
      <sec id="sec-2-3">
        <title>Visual Features</title>
        <p>
          In 2012, the bag–of–visual–words (BoVW) features using local descriptors were
a focus using the scale–invariant feature transform (SIFT) and the CIELab color
descriptor (namely bag–of colors, BoC [
          <xref ref-type="bibr" rid="ref12">12</xref>
          ]. In 2013, a combination of multiple
features was explored as this was a successfully used technique in 2012 [
          <xref ref-type="bibr" rid="ref10">10</xref>
          ]. The
following descriptors were chosen:
{ color and edge directivity descriptor (CEDD) [
          <xref ref-type="bibr" rid="ref14">14</xref>
          ];
{ bag of visual words using SIFT (BoVW) [
          <xref ref-type="bibr" rid="ref15">15</xref>
          ];
{ fuzzy color and texture histogram (FCTH) [
          <xref ref-type="bibr" rid="ref16">16</xref>
          ];
{ bag of colors (BoC) [
          <xref ref-type="bibr" rid="ref17">17</xref>
          ];
{ fuzzy color histogram (FCH) [
          <xref ref-type="bibr" rid="ref18">18</xref>
          ];
{ HSV color histogram [
          <xref ref-type="bibr" rid="ref19">19</xref>
          ];
{ color layout [
          <xref ref-type="bibr" rid="ref20">20</xref>
          ];
{ Tamura texture [
          <xref ref-type="bibr" rid="ref21">21</xref>
          ];
{ singular value decomposition (SVD) [
          <xref ref-type="bibr" rid="ref22">22</xref>
          ].
        </p>
        <p>
          These features were extracted from the test set (see Table 1). Then, the fusion of
the best features was performed to obtain a good feature set (see Table 2). Due
to time and resource limitations not all the possible combinations were tested
and only the features performing well alone were combined in a simple linear
way.
As seen in the ImageCLEFmed 2012 data set [
          <xref ref-type="bibr" rid="ref10">10</xref>
          ], a large portion of images
found in the biomedical literature are compound figures (figures consisting of
several subfigures). It was therefore important for the modality classification
task to be able to detect this modality as accurately as possible.
        </p>
        <p>
          For this reason, the compound figure separation application detailed in [
          <xref ref-type="bibr" rid="ref23">23</xref>
          ]
was run on all the images in the modality classification test set in order to
separate them into compound and non–compound figures. This way, the goal
was to only classify the single–plane images in the subsequent steps.
Feature
CEDD+BoVW
CEDD+BoVW+FCTH
CEDD+BoVW+FCTH+BoC
CEDD+BoVW+FCTH+BoC+FCH
CEDD+BoVW+FCTH+BoC+FCH+HSV
CEDD+BoVW+FCTH+BoC+FCH+HSV+Col. Layout
CEDD+BoVW+FCTH+BoC+FCH+HSV+Col. Layout+Tamura
CEDD+BoVW+FCTH+BoC+FCH+HSV+Col. Layout+Tamura+SVD
In the modality classification task some of the image categories were represented
by only very few annotated examples. Therefore, a training set expansion
strategy was applied. For this expansion the images in the training set were indexed
using only the textual information provided by Lucene. All the training images
were queried against the full 300,000 images of the ImageCLEFmed 2013 data
set and the 10 highest ranked retrieved images of each query were added as
training images into the class of the query image. Only the images belonging to
the ’compound or multipane images’ (COMP) class were not queried because
this class is well represented.
3
        </p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>Experimental Results</title>
      <p>This section details the techniques that were used to produce the runs for
ImageCLEFmed 2013 and then evaluates the runs.
3.1</p>
      <sec id="sec-3-1">
        <title>Modality Classi cation Runs</title>
        <p>This year, medGIFT submitted 10 runs using the techniques described in
Section 2. Two baseline runs were submitted: a visual and a textual. The visual
baseline uses the features described in Section 2.3. The textual baseline is
described in Section 2.2. The remaining runs are a combination of the baselines,
the compound figure detection (Section 2.4), and the training set expansion
(Section 2.5). The run IDs correspond to:
{ Run1–medgift2013 mc 5f : this run uses only visual information as a
baseline.
{ Run2–medgift2013 mc 5f separate: this run first classifies the images as
compound or non–compound (see Section 2.4). Then, the non–compound
images are classified using only visual information.
{ Run3–medgift2013 mc 5f exp k8: this run uses the same techniques as</p>
        <p>Run1 but over an expanded training set (see Section 2.5).
{ Run4–medgift2013 mc 5f exp separate k21: this run uses the same
techniques as Run2 but over an expanded training set.
{ Run5–medgift2013 mc text k8: the images are classified using the textual
information from the captions including semantic information.
{ Run6–medgift2013 mc mixed k8: this run uses visual and textual
information combined.
{ Run7–medgift2013 mc mixed exp k21: this run uses the same techniques
as Run6 but over an expanded training set.
{ Run8–mc mixed sem k8: this run uses the same techniques as Run6
including semantic information (see Section 2.2).
{ Run9–medgift2013 mc mixed exp sem k21: for this run visual and
textual features are extracted as well as the semantic information. An expanded
training set is used.
{ Run10–medgift2013 mc mixed exp sep sem k21: for this run the
images are first classified as compound or non–compound. Secondly, the non–
compound images are as in Run9.
3.2</p>
      </sec>
      <sec id="sec-3-2">
        <title>Compound Figure Separation Runs</title>
        <p>
          This year marked the introduction of a new subtask in ImageCLEF, the
separation of compound figures. MedGIFT submitted two compound figure separation
runs. Run11 simply serves as a point of reference, since it was also used in [
          <xref ref-type="bibr" rid="ref23">23</xref>
          ]
and thus has an advantage over other techniques. Run12 uses a different method,
which is not strictly designed for figure separation but provides a point of
comparison. The run used a region detection algorithm mainly focused on volumetric
medical image retrieval described in more detail in [
          <xref ref-type="bibr" rid="ref24">24</xref>
          ].
        </p>
        <p>{ Run11–... HESSO CFS: this run uses the MATLAB figure separation script
mentioned above, which was also used as a first step in the manual generation
of the ground truth.
{ Run12–... HESSO ... SCALE50 STANDARD: run that uses a
bidimensional version of the region detector mentioned above, at a scale of 50 pixels.
3.3</p>
      </sec>
      <sec id="sec-3-3">
        <title>Image{based Retrieval Runs</title>
        <p>
          This year the effect of modality filtering on the retrieval quality was investigated.
For this purpose, the full image dataset was classified using the method of the
best mixed run of the 2012 modality classification task [
          <xref ref-type="bibr" rid="ref12">12</xref>
          ]. The query images
of each topic were also classified and a set of query modalities was produced.
Images among the 1,000 top images retrieved by the retrieval methods that were
classified into one of these modalities were placed in top of the other retrieved
images.
        </p>
        <p>Three approaches of modality filtering were tested. In the first one named
”exact” only the modality detected by the KNN classifier for each query image
of the topic was put into the query modality set. The second named ”close”
puts all the modalities detected by the KNN classifier of any query image into
the topic. The third one named ”prefix”, is similar to the first but the broadest
modality (diagnostic, general, compound) was used instead of the exact modality
for boosting the image score in the retrieved set. Due to the limited number of
submissions the ”exact” approach was not submitted as it had a low performance
in preliminary tests on the ImageCLEF 2012 collection.</p>
        <p>
          Multiple features were used for visually indexing the dataset (see Section 2.3).
Apart from the features used last year (SIFT–based BoVW and BoC features),
more features were added for the image retrieval task. The CEDD and FCTH
descriptors were also used, due to their good performance on ImageCLEF 2012
challenge. BoVW and BoC features that contain spatial information were used.
For BoVW a spatial pyramid matching (SPM) approach was used [
          <xref ref-type="bibr" rid="ref25">25</xref>
          ] while an
n n spatial grid was used for BoC. The chosen pyramid depth level was L = 1
and the grid size was selected to be n = 3, after tuning on the ImageCLEF 2012
benchmark.
        </p>
        <p>For the text runs, a late fusion of full text search with caption search was
followed. Moreover, for each of these searches three different queries were fused
for each topic. The first one queried the topic query for exact matching. The
second connected the query terms with ’AND’, while the third used ’OR’ as a
connector.</p>
        <p>
          In the mixed runs, two different approaches were submitted. In the first
approach, a linear weighted late fusion was used. The weights were tuned using
the ImageCLEF 2012 benchmark. The second one used a late fusion (combMNZ)
of the visual and text runs to rerank the images in the result set that was
retrieved by the text run, similar to [
          <xref ref-type="bibr" rid="ref26">26</xref>
          ]. Preliminary experiments had shown
that weighted fusion had the best performance among all other fusion rules and
for this reason it was chosen for the comparison with the reranking runs. Below
the characteristics of each of the 10 runs submitted are presented:
{ Run13–medgift visual no lter: visual run that uses the 6 features (BoVW,
BoC, SPM BoVW, Grid BoC, CEDD and FCTH) and combMNZ fusion. No
modality filtering is used.
{ Run14–medgift visual close: same as Run13 but the ”close” modality
filtering approach is used.
{ Run15–medgift visual pre x: same as Run13 but the ”prefix” modality
filtering approach is used.
{ Run16–medgift text no lter: text run using caption and fulltext search
with combMNZ fusion. No modality filtering is used.
{ Run17–medgift text close: same as Run16 but the ”close” modality
filtering approach is used.
{ Run18–medgift text pre x: same as Run16 but the ”prefix” modality
filtering approach is used.
{ Run19–medgift mixed rerank no lter: mixed run fusing the methods
used in Run13 and Run16 to rerank the top 1,000 results of Run16. No
modality filtering is used.
{ Run20–medgift mixed rerank close: same as Run19 but the ”close”
modality filtering approach is used.
{ Run21–medgift mixed rerank pre x: same as Run19 but the ”prefix”
modality filtering approach is used.
{ Run22–medgift mixed weighted no lter: mixed run using linear weighted
fusion for Run13 and Run16. Weights were set to be forvisual: 0.2, text: 0.8.
        </p>
        <p>No modality filtering is used.
3.4</p>
      </sec>
      <sec id="sec-3-4">
        <title>Case{based Retrieval Runs</title>
        <p>For the case–based retrieval task, similar techniques to the ones in Image–based
retrieval task were submitted. For the mixed run, the visual features and the
captions were used for retrieving a list of images that was then mapped to a list
of associated articles. The new list was then fused with the article list returned
by the baseline full text search. Below the characteristics of the 5 submitted runs
are described:
{ Run23–medgift visual no lter casebased: visual run that uses the 6
features (BoVW, BoC, SPM BoVW, Grid BoC, CEDD and FCTH) and combMNZ
fusion. No modality filtering is used.
{ Run24–medgift visual close casebased: same as Run23 but the ”close”
modality filtering approach is used.
{ Run25–medgift visual pre x casebased: same as Run23 but the ”prefix”
modality filtering approach is used.
{ Run26–HES-SO-VS FULLTEXT LUCENE ENGLISH: baseline text
run using full text search. No modality filtering is used.
{ Run27–medgift mixed no lter casebased: mixed run using linear weighted
fusion for Run23 and Run25. Weights were visual: 0.2, text: 0.8. No modality
filtering is used.
3.5</p>
      </sec>
      <sec id="sec-3-5">
        <title>Modality Classi cation Evaluation</title>
        <p>This year medGIFT was the fourth group in the three types of run submissions.
Table 3 shows the results achieved by the submitted runs. The baselines runs
achieve the best results showing that the other techniques applied were not
improving the accuracy. The use of multiple features indicate an improvement
on the accuracy, achieving a better performance than last year’s “easier” test
data set. More work is necessary in the compound figure detection. In post–
submission experiments it was found that the compound figure detection step
did not achieve a better compound/non–compound separation accuracy ( 70%)
than the medGIFT baseline classifier ( 79%). This caused a worse performance
of the runs containing this step. Additionally, after the success of the expansion
of the database in 2012, the results show that it is deteriorating the approach.
Probably it is due to the fact that only textual information was used to expand
the database. Finally, the semantic step did not modify the results due to the
bug in the code.
The two runs submitted by medGIFT were the best and the worst in the list,
respectively, with only four runs being submitted. Table 4 shows the results
achieved by the runs submitted by medGIFT. Predictably, the run that was used
in previous work on the same data gave the best results, whereas the run using
the 2D region detector, which is not optimized for compound figure separation,
yielded mediocre results.
The results of the medGIFT runs are presented in Table 5. There are situations
when ”nofilter” or ”close” filter perform better depending on the type of run
(visual, textual or combined). Second best results were achieved in the visual
runs using the baseline run (”nofilter”). On mixed techniques medGIFT was
the second best group and on the textual runs medGIFT was the fourth group
when using ”close” filtering. In several queries the average precision was strongly
improved by the modality filtering, while other queries had much lower
performance, for example when the modality was not correctly detected. This indicates
that more accurate modality classification should further improve retrieval
performance. Results also show that the use of reranking in place of weighting for
the fusion achieves better results. This is important for large–scale retrieval as
visual search on the whole dataset is computationally costly. By having text
retrieval as a first step, the image–based retrieval search subspace is significantly
(magnitude of two orders) smaller.
In 2013, medGIFT submitted five runs in the case–retrieval task. The results
are listed in Table 6. This year medGIFT obtained the second position in both
visual and mixed runs. The results do not show significant differences with the
use or without modality filtering.
4</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>Conclusions</title>
      <p>This article describes the methods and results of the the medGIFT group for the
ImageCLEF 2013 medical tasks. Ten runs were submitted each for the ad–hoc
image retrieval and the modality classification tasks, five runs for the case–
based retrieval task and two runs in the new compound figure separation task.
In ImageCLEFmed 2013 medGIFT worked on runs based on multiple feature
combinations. Several strategies were explored and not all techniques obtained
improvements. Low results were obtained applying a database expansion
strategy. This performance may be due to the use of only textual information for the
indexing.
Run ID Run type MAP GM{MAP bpref P10 P30
Best ImageCLEF run Visual 0.0281 0.0009 0.0335 0.0429 0.0238
medgift visual close casebased Visual 0.0029 0.0001 0.0036 0.0086 0.0076
medgift visual no lter casebased Visual 0.0029 0.0001 0.0035 0.0086 0.0067
medgift visual pre x casebased Visual 0.0029 0.0001 0.0036 0.0086 0.0067
Best ImageCLEF run Textual 0.2429 0.1163 0.2417 0.2657 0.1981
HES-SO-VS FULLTEXT LUCENE Textual 0.1791 0.1107 0.1630 0.2143 0.1581
Best ImageCLEF run Mixed 0.1608 0.0779 0.1426 0.18 0.1257
medgift mixed no lter casebased Mixed 0.1467 0.0883 0.1318 0.1971 0.1457</p>
      <p>Among the 2013 results, it is possible to observe that the compound figure
separation is still a field to investigate in order to improve modality classification
accuracy.</p>
      <p>Future work of the medGIFT group aims at optimizing the use of the
modality classification to help the retrieval. A correct incorporation of the semantic
resources into the modality classification pipeline will be explored. MedGIFT
also plan to further investigate the compound figure separation task.
5</p>
    </sec>
    <sec id="sec-5">
      <title>Acknowledgments</title>
      <p>The research leading to these results has received funding from the European
Union’s Seventh Framework Programme under grant agreement 257528
(KHRESMOI) and 258191 (PROMISE).</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          1.
          <string-name>
            <surname>Caputo</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          , Muller, H.,
          <string-name>
            <surname>Thomee</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Villegas</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Paredes</surname>
            ,
            <given-names>R.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Zellhofer</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Goeau</surname>
            ,
            <given-names>H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Joly</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Bonnet</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Martinez</surname>
            <given-names>Gomez</given-names>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            ,
            <surname>Garcia</surname>
          </string-name>
          <string-name>
            <surname>Varea</surname>
          </string-name>
          ,
          <string-name>
            <given-names>I.</given-names>
            ,
            <surname>Cazorla</surname>
          </string-name>
          ,
          <string-name>
            <surname>C.</surname>
          </string-name>
          :
          <article-title>Imageclef 2013: the vision, the data and the open challenges</article-title>
          .
          <source>In: Working Notes of CLEF</source>
          <year>2013</year>
          (
          <article-title>Cross Language Evaluation Forum)</article-title>
          .
          <source>(September</source>
          <year>2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          2.
          <string-name>
            <surname>Clough</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          , Muller, H.,
          <string-name>
            <surname>Sanderson</surname>
            ,
            <given-names>M.:</given-names>
          </string-name>
          <article-title>The CLEF 2004 cross{language image retrieval track</article-title>
          . In Peters,
          <string-name>
            <given-names>C.</given-names>
            ,
            <surname>Clough</surname>
          </string-name>
          ,
          <string-name>
            <given-names>P.</given-names>
            ,
            <surname>Gonzalo</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            ,
            <surname>Jones</surname>
          </string-name>
          ,
          <string-name>
            <given-names>G.J.F.</given-names>
            ,
            <surname>Kluck</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            ,
            <surname>Magnini</surname>
          </string-name>
          , B., eds.:
          <article-title>Multilingual Information Access for Text, Speech and Images: Result of the fth CLEF evaluation campaign</article-title>
          . Volume
          <volume>3491</volume>
          of Lecture Notes in Computer Science (LNCS).,
          <string-name>
            <surname>Bath</surname>
          </string-name>
          , UK, Springer (
          <year>2005</year>
          )
          <volume>597</volume>
          {
          <fpage>613</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref3">
        <mixed-citation>
          3.
          <string-name>
            <surname>Clough</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          , Muller, H.,
          <string-name>
            <surname>Deselaers</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Grubinger</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lehmann</surname>
            ,
            <given-names>T.M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Jensen</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hersh</surname>
            ,
            <given-names>W.</given-names>
          </string-name>
          :
          <article-title>The CLEF 2005 cross{language image retrieval track</article-title>
          .
          <source>In: Cross Language Evaluation Forum (CLEF 2005). Lecture Notes in Computer Science (LNCS)</source>
          , Springer (
          <year>September 2006</year>
          )
          <volume>535</volume>
          {
          <fpage>557</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref4">
        <mixed-citation>
          4. Muller, H.,
          <string-name>
            <surname>Deselaers</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Deserno</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Clough</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kim</surname>
            ,
            <given-names>E.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hersh</surname>
            ,
            <given-names>W.</given-names>
          </string-name>
          :
          <article-title>Overview of the ImageCLEFmed 2006 medical retrieval and medical annotation tasks</article-title>
          . In:
          <article-title>Evaluation of Multilingual and Multi-modal Information Retrieval, 7th Workshop of the Cross-Language Evaluation Forum (CLEF 2006)</article-title>
          . Volume
          <volume>4730</volume>
          of Lecture Notes in Computer Science (LNCS).,
          <string-name>
            <surname>Alicante</surname>
          </string-name>
          , Spain, Springer (
          <year>2007</year>
          )
          <volume>595</volume>
          {
          <fpage>608</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref5">
        <mixed-citation>
          5. Muller, H.,
          <string-name>
            <surname>Deselaers</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Deserno</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kalpathy-Cramer</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kim</surname>
            ,
            <given-names>E.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hersh</surname>
            ,
            <given-names>W.</given-names>
          </string-name>
          :
          <article-title>Overview of the ImageCLEFmed 2007 medical retrieval and medical annotation tasks</article-title>
          .
          <source>In: Advances in Multilingual and Multimodal Information Retrieval, 8th Workshop of the Cross-Language Evaluation Forum (CLEF</source>
          <year>2007</year>
          ). Volume
          <volume>5152</volume>
          of Lecture Notes in Computer Science (LNCS)., Springer (
          <year>2008</year>
          )
          <volume>472</volume>
          {
          <fpage>491</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref6">
        <mixed-citation>
          6. Muller, H.,
          <string-name>
            <surname>Kalpathy-Cramer</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Jr.</surname>
            ,
            <given-names>C.E.K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hatt</surname>
            ,
            <given-names>W.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Bedrick</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hersh</surname>
            ,
            <given-names>W.</given-names>
          </string-name>
          :
          <article-title>Overview of the ImageCLEFmed 2008 medical image retrieval task</article-title>
          . In Peters,
          <string-name>
            <given-names>C.</given-names>
            ,
            <surname>Giampiccolo</surname>
          </string-name>
          ,
          <string-name>
            <given-names>D.</given-names>
            ,
            <surname>Ferro</surname>
          </string-name>
          ,
          <string-name>
            <given-names>N.</given-names>
            ,
            <surname>Petras</surname>
          </string-name>
          ,
          <string-name>
            <given-names>V.</given-names>
            ,
            <surname>Gonzalo</surname>
          </string-name>
          ,
          <string-name>
            <surname>J.</surname>
          </string-name>
          , Pen~as,
          <string-name>
            <given-names>A.</given-names>
            ,
            <surname>Deselaers</surname>
          </string-name>
          ,
          <string-name>
            <given-names>T.</given-names>
            ,
            <surname>Mandl</surname>
          </string-name>
          ,
          <string-name>
            <given-names>T.</given-names>
            ,
            <surname>Jones</surname>
          </string-name>
          ,
          <string-name>
            <given-names>G.</given-names>
            ,
            <surname>Kurimo</surname>
          </string-name>
          , M., eds.
          <source>: Evaluating Systems for Multilingual and Multimodal Information Access { 9th Workshop of the Cross-Language Evaluation Forum</source>
          . Volume
          <volume>5706</volume>
          of Lecture Notes in Computer Science (LNCS).,
          <string-name>
            <surname>Aarhus</surname>
          </string-name>
          , Denmark (
          <year>September 2009</year>
          )
          <volume>500</volume>
          {
          <fpage>510</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref7">
        <mixed-citation>
          7. Muller, H.,
          <string-name>
            <surname>Kalpathy-Cramer</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Eggel</surname>
            ,
            <given-names>I.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Bedrick</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Radhouani</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Bakke</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kahn</surname>
            ,
            <given-names>J.C.E.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hersh</surname>
            ,
            <given-names>W.</given-names>
          </string-name>
          :
          <article-title>Overview of the clef 2009 medical image retrieval track</article-title>
          . In:
          <article-title>Proceedings of the 10th international conference on Cross-language evaluation forum: multimedia experiments</article-title>
          .
          <source>CLEF'09</source>
          , Berlin, Heidelberg, Springer{ Verlag (
          <year>2010</year>
          )
          <volume>72</volume>
          {
          <fpage>84</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref8">
        <mixed-citation>
          8. Muller, H.,
          <string-name>
            <surname>Clough</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Deselaers</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Caputo</surname>
          </string-name>
          , B., eds.: ImageCLEF {
          <article-title>Experimental Evaluation in Visual Information Retrieval</article-title>
          . Volume
          <volume>32</volume>
          of The Springer International Series On Information Retrieval. Springer, Berlin Heidelberg (
          <year>2010</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref9">
        <mixed-citation>
          9.
          <string-name>
            <surname>Kalpathy-Cramer</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          , Muller, H.,
          <string-name>
            <surname>Bedrick</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Eggel</surname>
            ,
            <given-names>I.</given-names>
          </string-name>
          , Garc a Seco de Herrera,
          <string-name>
            <given-names>A.</given-names>
            ,
            <surname>Tsikrika</surname>
          </string-name>
          ,
          <string-name>
            <surname>T.</surname>
          </string-name>
          :
          <article-title>The CLEF 2011 medical image retrieval and classi cation tasks</article-title>
          .
          <source>In: Working Notes of CLEF</source>
          <year>2011</year>
          (
          <article-title>Cross Language Evaluation Forum)</article-title>
          .
          <source>(September</source>
          <year>2011</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref10">
        <mixed-citation>
          10. Muller, H., Garc a Seco de Herrera,
          <string-name>
            <given-names>A.</given-names>
            ,
            <surname>Kalpathy-Cramer</surname>
          </string-name>
          ,
          <string-name>
            <surname>J.</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Demner</given-names>
            <surname>Fushman</surname>
          </string-name>
          ,
          <string-name>
            <given-names>D.</given-names>
            ,
            <surname>Antani</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            ,
            <surname>Eggel</surname>
          </string-name>
          ,
          <string-name>
            <surname>I.</surname>
          </string-name>
          :
          <article-title>Overview of the ImageCLEF 2012 medical image retrieval and classication tasks</article-title>
          .
          <source>In: Working Notes of CLEF</source>
          <year>2012</year>
          (
          <article-title>Cross Language Evaluation Forum)</article-title>
          .
          <source>(September</source>
          <year>2012</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref11">
        <mixed-citation>
          11.
          <string-name>
            <surname>Garc</surname>
            a Seco de Herrera,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kalpathy-Cramer</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <given-names>Demner</given-names>
            <surname>Fushman</surname>
          </string-name>
          ,
          <string-name>
            <given-names>D.</given-names>
            ,
            <surname>Antani</surname>
          </string-name>
          ,
          <string-name>
            <surname>S.</surname>
          </string-name>
          , Muller, H.:
          <article-title>Overview of the ImageCLEF 2013 medical tasks</article-title>
          .
          <source>In: Working Notes of CLEF</source>
          <year>2013</year>
          (
          <article-title>Cross Language Evaluation Forum)</article-title>
          .
          <source>(September</source>
          <year>2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref12">
        <mixed-citation>
          12.
          <string-name>
            <surname>Garc</surname>
            a Seco de Herrera,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Markonis</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Eggel</surname>
            ,
            <given-names>I.</given-names>
          </string-name>
          , Muller, H.:
          <article-title>The medGIFT group in ImageCLEFmed 2012</article-title>
          . In: Working Notes of CLEF 2012 (
          <article-title>Cross Language Evaluation Forum)</article-title>
          . (
          <year>2012</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref13">
        <mixed-citation>
          13.
          <string-name>
            <surname>Konstatin</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Momtchev</surname>
            ,
            <given-names>V.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Markonis</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Schlegl</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          :
          <article-title>Report on consistency checking rules for information extraction</article-title>
          .
          <source>Deliverable d5</source>
          .
          <article-title>4 of the khresmoi project</article-title>
          ,
          <source>ONTOtext</source>
          (
          <year>2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref14">
        <mixed-citation>
          14. Chatzichristo s,
          <string-name>
            <given-names>S.A.</given-names>
            ,
            <surname>Boutalis</surname>
          </string-name>
          ,
          <string-name>
            <surname>Y.S.:</surname>
          </string-name>
          <article-title>CEDD: Color and edge directivity descriptor: A compact descriptor for image indexing and retrieval</article-title>
          .
          <source>In: Lecture notes in Computer Sciences</source>
          . Volume
          <volume>5008</volume>
          . (
          <year>2008</year>
          )
          <volume>312</volume>
          {
          <fpage>322</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref15">
        <mixed-citation>
          15.
          <string-name>
            <surname>Lowe</surname>
            ,
            <given-names>D.G.</given-names>
          </string-name>
          :
          <article-title>Distinctive image features from scale-invariant keypoints</article-title>
          .
          <source>International Journal of Computer Vision</source>
          <volume>60</volume>
          (
          <issue>2</issue>
          ) (
          <year>2004</year>
          )
          <volume>91</volume>
          {
          <fpage>110</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref16">
        <mixed-citation>
          16. Chatzichristo s,
          <string-name>
            <given-names>S.A.</given-names>
            ,
            <surname>Boutalis</surname>
          </string-name>
          ,
          <string-name>
            <surname>Y.S.:</surname>
          </string-name>
          <article-title>FCTH: Fuzzy color and texture histogram: A low level feature for accurate image retrieval</article-title>
          .
          <source>In: Proceedings of the 9th International Workshop on Image Analysis for Multimedia Interactive Service</source>
          . (
          <year>2008</year>
          )
          <volume>191</volume>
          {
          <fpage>196</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref17">
        <mixed-citation>
          17.
          <string-name>
            <surname>Garc</surname>
            a Seco de Herrera,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Markonis</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          , Muller, H.:
          <article-title>Bag of colors for biomedical document image classi cation</article-title>
          . In Greenspan, H., Muller, H., eds.:
          <article-title>Medical Content{based Retrieval for Clinical Decision Support</article-title>
          .
          <source>MCBR{CDS 2012, Lecture Notes in Computer Sciences (LNCS)</source>
          (
          <year>October 2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref18">
        <mixed-citation>
          18.
          <string-name>
            <surname>Han</surname>
            ,
            <given-names>J</given-names>
          </string-name>
          ., Ma, K.K.:
          <article-title>Fuzzy color histogram and its use in color image retrieval</article-title>
          .
          <source>IEEE Transactions on Image Processing</source>
          <volume>11</volume>
          (
          <issue>8</issue>
          ) (
          <year>2002</year>
          )
          <volume>944</volume>
          {
          <fpage>952</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref19">
        <mixed-citation>
          19.
          <string-name>
            <surname>Sural</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Qian</surname>
            ,
            <given-names>G.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Pramanik</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          :
          <article-title>Segmentation and histogram generation using the hsv color space for image retrieval</article-title>
          .
          <source>In: Proceedings of the International Conference on Image Processing. ICIP'</source>
          <year>2002</year>
          (
          <year>2002</year>
          )
          <volume>589</volume>
          {
          <fpage>592</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref20">
        <mixed-citation>
          20.
          <string-name>
            <surname>Kasutani</surname>
            ,
            <given-names>E.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Yamada</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          :
          <article-title>The MPEG{7 color layout descriptor: a compact image feature description for high-speed image/video segment retrieval</article-title>
          .
          <source>In: Proceedings of the International Conference on Image Processing. ICIP'</source>
          <year>2001</year>
          (
          <year>2001</year>
          )
          <volume>674</volume>
          {
          <fpage>677</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref21">
        <mixed-citation>
          21.
          <string-name>
            <surname>Tamura</surname>
            ,
            <given-names>H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Mori</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Yamawaki</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          :
          <article-title>Textural features corresponding to visual perception</article-title>
          .
          <source>IEEE Transactions on Systems, Man and Cybernetics</source>
          <volume>8</volume>
          (
          <issue>6</issue>
          ) (
          <year>June 1978</year>
          )
          <volume>460</volume>
          {
          <fpage>473</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref22">
        <mixed-citation>
          22.
          <string-name>
            <surname>Jiao</surname>
            ,
            <given-names>Y.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Yang</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Wang</surname>
            ,
            <given-names>H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Niu</surname>
            ,
            <given-names>X.</given-names>
          </string-name>
          :
          <article-title>SVD based robust image content retrieval</article-title>
          .
          <source>In: Proceedings of the 2006 International Conference on Intelligent Information Hiding and Multimedia</source>
          . IIH-MSP '
          <volume>06</volume>
          (
          <year>2006</year>
          )
          <volume>351</volume>
          {
          <fpage>354</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref23">
        <mixed-citation>
          23.
          <string-name>
            <surname>Chhatkuli</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Markonis</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Foncubierta-Rodr guez</surname>
          </string-name>
          , A.,
          <string-name>
            <surname>Meriaudeau</surname>
            ,
            <given-names>F.</given-names>
          </string-name>
          , Muller, H.:
          <article-title>Separating compound gures in journal articles to allow for sub gure classi - cation</article-title>
          . In: SPIE,
          <string-name>
            <surname>Medical</surname>
            <given-names>Imaging.</given-names>
          </string-name>
          (
          <year>2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref24">
        <mixed-citation>
          24.
          <string-name>
            <surname>Foncubierta-Rodr guez</surname>
          </string-name>
          , A., Muller, H.,
          <string-name>
            <surname>Depeursinge</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          :
          <article-title>Region{based volumetric medical image retrieval</article-title>
          .
          <source>In: SPIE Medical Imaging: Advanced PACS{based Imaging Informatics and Therapeutic Applications</source>
          . (
          <year>2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref25">
        <mixed-citation>
          25.
          <string-name>
            <surname>Lazebnik</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Schmid</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Ponce</surname>
          </string-name>
          , J.:
          <article-title>Beyond bags of features: Spatial pyramid matching for recognizing natural scene categories</article-title>
          .
          <source>In: Proceedings of the 2006 IEEE Conference on Computer Vision and Pattern Recognition. CVPR</source>
          , Washington, DC, USA, IEEE Computer Society (
          <year>2006</year>
          )
          <volume>2169</volume>
          {
          <fpage>2178</fpage>
        </mixed-citation>
      </ref>
      <ref id="ref26">
        <mixed-citation>
          26.
          <string-name>
            <surname>Clinchant</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Ah-Pine</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Csurka</surname>
          </string-name>
          , G.:
          <article-title>Semantic combination of textual and visual information in multimedia retrieval</article-title>
          .
          <source>In: Proceedings of the 1st ACM International Conference on Multimedia Retrieval. ICMR '11</source>
          ,
          <string-name>
            <surname>ACM</surname>
          </string-name>
          (
          <year>2011</year>
          )
          <volume>44</volume>
          :
          <fpage>1</fpage>
          {
          <issue>44</issue>
          :
          <fpage>8</fpage>
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>