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<article xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Integration of Multi Criteria Analysis Methods to a Spatio Temporal Decision Support System for Epidemiological Monitoring</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Farah Amina Zemri</string-name>
          <email>zemriamina@gmail.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Djamila Hamdadou</string-name>
          <email>dzhamdadoud@yahoo.fr</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>LIO Laboratory, BP 1524 EL M' Naouer, Oran University</institution>
          ,
          <country country="DZ">Algeria</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>LIO Laboratory, BP 1524 EL M' Naouer, Oran University</institution>
          ,
          <country country="DZ">Algeria</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2014</year>
      </pub-date>
      <fpage>2</fpage>
      <lpage>4</lpage>
      <abstract>
        <p>- The present study aims to integrate Multi Criteria Analysis Methods (MCAM) to a decision support system based on SOLAP technology, modeled and implemented in other work. The current research evaluates on the one part the benefits of SOLAP in detection and location of epidemics outbreaks and discovers on another part the advantages of multi criteria analysis methods in the assessment of health risk threatening the populations in the presence of the risk (presence of infectious cases) and the vulnerability of the population (density, socio-economic level, Habitat Type, climate...) all that, in one coherent and transparent integrated decision-making platform. We seek to provide further explanation of the real factors responsible for the spread of epidemics and its emergence or reemergence. In the end, our study will lead to the automatic generation of a risk map which gives a classification of epidemics outbreaks to facilitate intervention in order of priority.</p>
      </abstract>
      <kwd-group>
        <kwd>- Multi criteria Analysis Decision Support (MCAM)</kwd>
        <kwd>Spatial Data Mining (SDM)</kwd>
        <kwd>Spatial on Line Analysis Processing (SOLAP)</kwd>
        <kwd>Data warehouse (DW)</kwd>
        <kwd>Epidemiological Surveillance (SE)</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. INTRODUCTION</title>
      <p>Epidemic prevention is a public health concern.
It is a real challenge. Identification of residential
areas (urban and non-urban) exposed to
epidemics would help in riding of these
phenomena of public health with prevention
strategy and careful management. The medical
management of these diseases would be more
effective. The use of information technologies
greatly facilitates the realization of such
objective. In order to identify a good prevention
strategy against epidemics and to ensure a
reflect management of propagation
phenomenon, a good epidemiological
surveillance system must be developed for
monitoring of the disease and identifying areas
with epidemics outbreaks.</p>
      <p>The article describes in section 2 our
contribution. In section 3, the main works in the
field of spatial decision support using MCAM are
presented. Section 4 describes, EPISOLAP
system and the proposed approach is illustrated
in details in section 5. Multi Criteria formulation
problem is given in section 6 and section 7 is
devoted to the PROMETHEE method tool used
for the development of multi criteria decision
support system suggested. A real case study
which is a first validation step of our proposed
approach is detailed in section 8 and finally, we
conclude our discussion in Section 9, giving
some perspectives.
2. PROBLEMATIC AND CONTRIBUTION
Business intelligence provides new solutions for
modeling, querying and visualization of data in
an objective decision support. Multidimensional
or hyper-cube models allow structuring the data
for policy analysis by clarifying the notion of
dimension.</p>
      <p>The integration of spatial data into OLAP
systems is a major challenge. Indeed,
geographic information is frequently present
implicitly or explicitly in the data, but generally
under-used in the decision making process.
Coupling OLAP systems and Geographical
Information Systems in Spatial OLAP (SOLAP)
systems is promising. We believe that the
combination of SOLAP technology once
designed and implemented with Multi Criteria
Analysis Methods (MCAM) is an interesting
voice because it can lead to richer data analysis.
surveillance data identified
specialized health structures.
in
different</p>
    </sec>
    <sec id="sec-2">
      <title>3. RELATED WORKS</title>
      <p>
        In the context of single-actor decision support,
several decision support systems in TP
(Territory Planning) caught our attention. In [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ],
the system MEDUSAT is proposed for locating
the site of a waste treatment plant in Tunisia.
MEDUSAT combines a GIS tool allowing
creation of homogenous areas determined from
spatial data and common land (constituting a
similarity index); these areas constitute the set
of actions which are then processed by Multi
Criteria Analysis Methods (MCAM).
      </p>
      <p>
        The author in [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ] proposed a decision process
for water management in urban environment
and in [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ]; authors presented some tools for
decision support in local communities in order to
address water management problems. In [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ],
Multi Criteria analysis was used as a tool for
decision making for spatial localization of areas
under heavy human pressure, a case study of
the department of Naama in Algeria was
presented in the same work. Various decision
support systems rich in spatial tools and Multi
Criteria Analysis Methods were developed for
management and decision making in territorial
problems (water, air, natural areas,
transportation, energy, waste, health planning,
risk management, . . . ) [
        <xref ref-type="bibr" rid="ref13">13</xref>
        ].
      </p>
      <p>
        All these systems integrate in various levels
multi criteria analysis tools coupled with GIS, but
they consider criteria as independent and unable
to model any interaction between them
(interchangeability, correlation, preferential
dependence . . .). In [
        <xref ref-type="bibr" rid="ref14">14</xref>
        ], we have already
discussed significantly the inclusion of
correlation criteria, in the MCDA methods,
particularly”ELECTRE TRI”, by introducing the
Choquet integral (instead of the arithmetic sum)
as an aggregation operator. In [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ], the main
objective is to develop a decision support
system, for itinerary road modification in the
case of hazardous materials transport. In [
        <xref ref-type="bibr" rid="ref10">10</xref>
        ], a
multicriteria decision support system for
industrial diagnosis was developed.
4. DESCRIPTION OF EPISOLAP SYSTEM
The study that was conducted by our previous
works in "EPISOLAP” project [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ] aimed to
identify and predict the health risk according to
The analysis is done by SOLAP tool, but it is
limited to alphanumeric data and does not
exploit the geographical location and the link
neighborhood. Our current work aims to emerge
from all these data, the relevant structures of the
health risk that can support the effort of
surveillance, direct action eradication and
strengthen the system of prevention.
      </p>
      <p>More specifically, it is also spending limits of
"EPISOLAP" and integrate the spatial nature of
the data (here the epidemic outbreaks) and the
interaction with the geographical environment
especially that this is a disease (Tuberculosis)
which is rapidly spreading (or the concept of
neighborly relations is very important) allowing,
in this application example, to explain and
predict health risks threatening the population,
taking into account their geographical context.
We show in Figure 2 some results obtained from
the analysis of surveillance data by EPISOLAP
system.</p>
    </sec>
    <sec id="sec-3">
      <title>OUR CONTRIBUTION</title>
      <p>In the present study, we began a new SOLAP
formulation which aims to integrate Multi criteria
analysis methods to answer to the requirements
of epidemiological surveillance and to the most
boring questions of decision makers in public
health, allowing them to prevent the emergence
of new epidemics outbreaks (prediction) and
taking into account the socio-environmental
factors favoring contamination.</p>
      <p>The "EPISOLAP" system had as main objective
the detection and localization of disease
outbreaks; it remains to know which outbreaks
are the most at-risk; we therefore proposed a
classification of these outbreaks using different
criteria which fall in the identification of health
risk. We study the possibility of integration of
multi-criteria analysis methods that are formal
methods that have proven their efficiency in
space and have demonstrated their ability to
identify spatial problems. These methods have
been applied in different studies conducted in
our team for a decade and in different fields
(Transport, Planning territory, Production
Management and Industrial domain) where we
come the idea of designing a spatial decision
support system based on the integration of
SOLAP technology and Multi criteria analysis
methods whose objective is to identify the
epidemiological spread phenomenon and make
it controlled problem consequently increased
and effective epidemiological surveillance.
</p>
      <p>The role of SOLAP would be the
location of outbreaks of epidemics.
 The role of MCAM is the classification of
disease outbreaks to facilitate
intervention in order of priority.</p>
      <p>Our objective is to model the problem of
epidemiological surveillance to a Multi criteria
problem taking into account the various criteria
affecting the spread of the disease.
6.</p>
    </sec>
    <sec id="sec-4">
      <title>MULTI</title>
      <p>PROBLEM</p>
    </sec>
    <sec id="sec-5">
      <title>CRITERIA</title>
    </sec>
    <sec id="sec-6">
      <title>FORMULATION</title>
      <p>
        The proposed decisional model based on Multi
Criteria Decision support is largely inspired from
that proposed in [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]
      </p>
    </sec>
    <sec id="sec-7">
      <title>6.1 The structuring phase</title>
      <p>This first phase aims to identify the problem
(geographical location of study area using the
GIS, identification of different criteria) and the
basic choices on how to approach it. This phase
aims, also, to formalize two basic elements of
the decisional situation:

</p>
      <p>Identify actions: the identification of all
the potential actions is a very significant
step in any decision support approach,
especially when the multi-criteria
analysis method proceeds by partial
aggregation. It is very important that the
set of all the actions is complete
because its modification during the
analysis can cause a recurrence of
multi-criteria analysis.</p>
    </sec>
    <sec id="sec-8">
      <title>Identify criteria: the list of criteria</title>
      <p>obtained by aggregating the
corresponding factors (sub-criteria)
should be as complete as possible.
These criteria must be related to
constraints and objectives used in the
generation activities. The family of the
most relevant criteria must verify the
conditions of exhaustively, consistency
and independence.</p>
    </sec>
    <sec id="sec-9">
      <title>6.2 The operational phase</title>
      <p>This second phase is the analytical process of
the study. Its two main objectives are the
evaluation criteria, then the aggregation of this
information by a multi-criteria analysis exploiting
the multi-criteria methods of classification
namely (PROMETHEE family methods).</p>
    </sec>
    <sec id="sec-10">
      <title>6.3 The implementation phase</title>
      <p>
        This third phase is primarily the result of social
acceptance. However, it also includes the
implementation of the decision and the control of
this implementation. The main phases and
stages of the proposed model are designed in
Figure 3.
The functional architecture of the proposed
Decision Support System based on MCAM is
illustrated on the flow chart of figure 4.
7. PROMETHEE MULTI CRITERIA METHOD
The multi-criteria analysis method PROMETHEE
(Preference Ranking Organisation Method for
Enrichment Evaluations) [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ] treats a γ problem.
The main advantages of PROMETHEE are:



      </p>
      <p>The simplicity and intuitive aspect of the
method
The power of its preference function
The simplicity of the operating phase of
the method
The method PROMETHEE I provides the
user with a ranking of different actions
(outbreaks). The problem is that this method
does not classify all actions. Some actions may
remain unmatched. PROMETHEE II method
allows removing this incomparability. The
principle of this method is to establish a
numerical process of comparing each action
relative to all other actions. Thus, it is possible to
calculate more (merit) or less (demerit) of each
action compared to all others. The result of this
comparison allows the orderly classification of
actions. The implementation of the method can
be reduced to perform the following three steps:
7.1 Choice of generalized criteria
each criterion C1, C2 ... Cm be associated with
a generalized criterion chosen based on a
preference function and scale effects are
eliminated.
7.2 Determination of an outranking relation
in a second phase, it is necessary to determine
a relationship outranking through a preference
index that quantifies the preferences of the
decision maker. The preference intensity is
calculated as follows:
p (d) = 0 if d qj, p(d) = (d-qj) / (pj, qj) if qj &lt;d  pj
and p (d) = 1 if not "a" and "b" are two actions
potential, "d" is the difference between the
performance of "a" and performance of "b" (gj
(a) - gj (b)). qj is the indifference threshold, and
pj is the preference threshold.
7.3 Assessment of preferences
the evaluation of the preference of the decision
maker is ensured by the inclusion of incoming
and outgoing flows.</p>
      <p></p>
    </sec>
    <sec id="sec-11">
      <title>Calculating the preference indicator</title>
      <p>(a, b) = Ʃ Wj * Pj(a, b) / ƩWj
Wj is the weight of criterion j</p>
    </sec>
    <sec id="sec-12">
      <title>Calculation of incoming flows</title>
      <p>ᶲ+ (a) =Ʃ</p>
      <p>(a, x)
 Calculation of outgoing flows
ᶲ- (a) =Ʃ (x, a)</p>
    </sec>
    <sec id="sec-13">
      <title>Calculation of global flows</title>
      <p>ᶲ (a) =ᶲ+ (a) -ᶲ- (a)
The general principle of operation by
PROMETHEE (I and II) is given by the flowchart
illustrated by the figure 5.</p>
    </sec>
    <sec id="sec-14">
      <title>8. CASE STUDY</title>
      <p>
        Due to demographic and socio-economic
situation in Algeria, further progress is still
needed to achieve the objectives of the recovery
plan for the fight against tuberculosis
(20062015) that are part of the Millennium
Development Goals (MDG), and the new
strategy "Stop TB" recommended by World
Health Organization since 2006: "Stop the
increase in the incidence of tuberculosis and
begin to reduce throughout the national territory"
[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ].
      </p>
      <p>Among the main measures adopted by this
national program is to improve the reporting of
cases of tuberculosis and their monitoring by the
generalization of electronic surveillance system.
Our project is integrated in this context to assist
in achieving these goals by developing a spatial
decision support System (SDSS) capable of
carrying help in epidemiological surveillance to
identify the problem of the spread of tuberculosis
which is an uncontrollable kind problem.
In this regard, we note the little comparative
studies that can help to determine what extent
the socio-economic transformations that know
the study area and environmental scenarios
helped in the spread and transmission of the
disease.</p>
    </sec>
    <sec id="sec-15">
      <title>8.1 Identification of the study area</title>
      <p>
        The field in the context of this study is the region
of Oran in Algeria. The establishment of a
geolocation of residential areas of population said
"poor" most exposed would observe places
where epidemic could spread rapidly and most
widely. Professor Bouziani, epidemiologist at
Bio-statistics department in the Faculty of
Medicine INESSMO of Oran University, we were
oriented towards the disease of tuberculosis,
which still represents a continuing hazard
lowering the population in the region of Oran[
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] .
      </p>
    </sec>
    <sec id="sec-16">
      <title>8.2 Considered criteria</title>
      <p>One of the proposed solutions in this study to
increase case detection was to identify
populations at risk for Tuberculosis. The
objective of our research is precisely to
understand the dynamics of tuberculosis in Oran
depending on the criteria mentioned in section 5,
above to create an index of vulnerability of
population living in the region, and achieve in
producing a risk map of tuberculosis.</p>
      <p>Risk is assessed according to the frequency of
occurrence of one or more parameters about the
case. Risk is defined by the simultaneous
presence of the hazard and the vulnerability of
the population
Thus, it is possible to create a risk index based
on the parameters that identify the presence of
the hazard (e.g. the presence of infectious cases
...) and identifiers of the population vulnerability
(e.g. the density (overcrowding), location, type of
housing, unemployment ...)
8.2.1</p>
      <sec id="sec-16-1">
        <title>Presence of infectious cases (Medical</title>
      </sec>
      <sec id="sec-16-2">
        <title>Criteria)</title>
        <p>The risk of Tuberculosis is defined in three
classes according to the presence of infectious
cases (proven cases) and the presence of cases
of non-infectious (unproven) but potentially
infectious tuberculosis. The hazard is so strong
in the foyer in question, there is at least one
infectious case; danger is low if there are no
cases of tuberculosis detected as contagious but
there is at least one case of tuberculosis
identified in the outbreak; hazard is zero if no
cases of tuberculosis have been identified
throughout the year (probability of the event
"with a case of tuberculosis" = 0).
There is a little information in the literature about
the "social vulnerability" and socio-economic
data that may be related to the presence of
tuberculosis. According to the availability of
these vulnerable settings, our choice was
focused on the "population density" parameter
that appears the most significant. Indeed,
overcrowding in a given region favors
contamination and the spread of epidemics
including tuberculosis enough direct contact with
the patient with the disease carry the virus by air
voice. A denser population is more vulnerable to
be contaminated by the presence of the hazard
course here is the presence of infectious cases.
8.2.3</p>
      </sec>
      <sec id="sec-16-3">
        <title>Habitat Type (Demographic Criteria)</title>
        <p>This criterion is calculated by the number of
precarious constructions generally occupying
shantytowns:
8.2.4</p>
      </sec>
      <sec id="sec-16-4">
        <title>Number of inactive criteria) (Demographic</title>
        <p>The number of inactive is resumed in our study
on the number of unemployed people in the
regions.
8.2.5</p>
      </sec>
      <sec id="sec-16-5">
        <title>Humidity (Climatic Criteria)</title>
        <p>Climate humidity is a very important parameter
which promotes the spread of bacteria (eg the
cock bacillus responsible for the TB disease).
being unable to have the annual average
humidity of all the regions of Oran (presence of
two measure stations only: sénia and arzew) we
have identified, through a weather specialist in
the National Office Of Weather in Oran, a scale
of 4 points (1-2-3-4) that classes the regions
from the wettest (measure = 1) to the driest
(measure = 4)</p>
      </sec>
    </sec>
    <sec id="sec-17">
      <title>8.3 Performances Table</title>
      <p>The information layers involved in our
Tuberculosis risk model: the hazard,
vulnerability: Presence of infectious cases,
Population, Density, poverty level and the rate of
humidity, will be crossed in EPISOLAP-MINING,
showing areas at which interactions between a
vulnerable population against Tuberculosis and
patients who are likely to transmit the disease
(Proven / Unproven) are most intense.</p>
      <p>The objective of this multi-criteria modeling of
the spread of Tuberculosis disease problem will
result in a classification of outbreaks of
epidemics from most favorable to least
favorable. These areas are supposed to be
most at risk, or the most "hazardous
epidemiologically" that will lead to the
development of a risk map. Actions in our Multi
Criteria Analysis study are the foci of epidemics
detected previously by the "EPISOLAP" system
(26 outbreaks considered).
1
2
2
3
2
1
1
1
1
1
4
4
In the frequent case where the analysis of the
consequences of potential actions led to build
several criteria is multi criteria analysis to
provide answers to the problem.</p>
      <p>For any given action, and for each criterion a
preference threshold p, indifference q and veto
threshold v are estimated, knowing that
PROMETHEE methods do not exploit the veto
threshold who is a subjective parameter
expressed by the decision maker. Each
criterion is assigned a weight k reflecting its
contribution to the final decision. The result of
the analysis of the consequences is presented in
a table of performance. For simplification
reasons we have chosen that: p (PREF) =q
(INDI) =1</p>
    </sec>
    <sec id="sec-18">
      <title>8.5 Results of ranking</title>
      <p>The multi criteria method that was implemented
for ranking outbreaks of epidemics on the map
of Oran is the method PROMETHEE II witch
constructs an outranking relation value, based
on the comparison of the actions in pairs; its
purpose is to store the actions of the best one to
the worst. Figure 7 shows a risk map which
gives a classification of outbreaks of epidemics
from more epidemiological risk region at the
least epidemiological risk region using a legend.
The result of ranking was visualized on a map
using the Map Info Professional 11.0 GIS.</p>
    </sec>
    <sec id="sec-19">
      <title>CONCLUSION AND PERSPECTIVES</title>
      <p>We were able, through this case study, see how
our proposed model in epidemiological
surveillance “EPISOLAP-MINING and its
effectiveness in terms of the provision makers of
public health relevant information enabling them
to see relationships between phenomena, while
encouraging them to discover knowledge and
produce the right decision by acting effectively in
time and in space. This prediction process
generated by the integration of SOLAP
technology and multi criteria decision methods
used in our approach makes the originality of
our contribution and presents to us the purpose
of our proposed model.</p>
      <p>Even if deficiencies remain supplement to
achieve our goals of departure; we have less
initiated in the present paper a predictive model
using multi criteria analysis to develop a risk
map that helps decision makers in public health
to take the necessary devices to avoid a health
risk. Through this study and our future work, we
try to integrate the data mining techniques to our
system EPISOLAP-MINING, focusing on the
creation of spatial operators that lack in our
Spatial Decision Support system.</p>
      <p>Although limitations appear from first glance,
before the major achievement of such
challenges, we have initiated in this paper the
first nucleus of this new approach itself
constitutes a first validation of our spatial
decision support systems for monitoring
epidemiological EPISOLAP-MINING</p>
    </sec>
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