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  <front>
    <journal-meta />
    <article-meta>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Shirley Coyle</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>James Connolly</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Jennifer Deignan</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Mathilde Sabourin</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Eoghan MacNamara</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Conor O'Quigley</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Kieran Moran</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Joan Condell</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Kevin Curran</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Dermot Diamond</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Faculty of Computing and Engineering, Ulster University</institution>
          ,
          <addr-line>Magee, Derry</addr-line>
          ,
          <country>N Ireland</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Insight, Centre for Data Analytics, National Centre for Sensor Research, Dublin City University</institution>
          ,
          <addr-line>Glasnevin, Dublin 9</addr-line>
          ,
          <country country="IE">Ireland</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>Wearable sensors for fitness tracking are becoming increasingly popular and are set to increase as smartwatches begin to dominate the wearable technology market. Wearable technology provides the capacity to track long-term trends in the wearer's health. In order for this to be adopted the technology must be easy to use and comfortable to wear. Textile based sensors are ideal as they conform to the body and can be integrated into the wearer's everyday wardrobe. This work discusses fabric stretch sensors that can measure body movements. An application using a sensor glove for home assessment of Rheumatoid Arthritis is presented. This work is the result of a multidisciplinary effort, involving expertise in material science and functional design, computer science, human health and performance and influenced by the end user needs.</p>
      </abstract>
      <kwd-group>
        <kwd>The role of textile sensors</kwd>
        <kwd />
        <kwd>Wearable sensors</kwd>
        <kwd>piezo-resistive textile</kwd>
        <kwd>home monitoring</kwd>
        <kwd>rheumatoid arthritis</kwd>
        <kwd>personal health</kwd>
        <kwd>smart garments</kwd>
        <kwd>interactive textiles</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>
        For healthcare delivery to become more personalised it is essential to find ways to track
the long- term physiology of the person. Clinical visits are sporadic, and rely on
patient’s subjective reporting of their symptoms. Quantifiable measures of physiological
output could provide a more definitive account of personal well-being. Smartphones
are already equipped with motion and location sensing devices which, from a healthcare
perspective, can be used to monitor activity levels and exercise. The use of a
smartphone is a successful model as it does not encumber the user with additional
technology, and many people have access to this hardware. The concept of a smart garment
is similar; by integrating miniature or textile-based sensors into garments, the garment
functionality can be extended to monitor the wearer’s health without the need for
additional technology, wires or supplementary devices. Wearable sensors and smart textiles
therefore offer the possibility of monitoring the body in an unobtrusive manner
        <xref ref-type="bibr" rid="ref10 ref2 ref4 ref7">(Castano and Flatau, 2014, Coyle et al., 2014, Stoppa and Chiolerio, 2014, O'Quigley et al.,
2014)</xref>
        . Smart garments may be used to assess chronic conditions at home and as a
rehabilitation tool. As part of a user interface system, visual and audio feedback can be
given to motivate users and encourage adherence to prescribed exercises. Home
monitoring of exercise performance can also be used to indicate the effectiveness of
treatment to therapists. This can allow a personalised approach to healthcare delivery and
rehabilitation strategy. The wearer’s own “smart” garments can log their physiology
automatically as they go about daily tasks creating a personal physiological diary of
their wellbeing.
      </p>
      <p>Rheumatoid Arthritis (RA) is a chronic condition requiring on-going treatment and
disease management. It is an auto-immune disease which attacks the synovial tissue
lubricating skeletal joints and is characterized by pain, swelling, stiffness and
deformity(National Collaborating Centre for Chronic Conditions (UK), 2009). This systemic
condition affects the musculoskeletal system, including bones, joints, muscles and
tendons that contribute to loss of function and Range of Motion (ROM). Early
identification of RA is important to initiate correct drug treatment, reduce disease activity and
ultimately lead to its remission.</p>
      <p>This paper discusses the use of textile stretch sensors that can detect kinematics of
the body to monitor joint movements. We present the design of a sensor system to
assist the management of RA through home monitoring of hand exercises. The glove
has been designed with the user’s dexterity and comfort in mind. Fabric sensors are
comfortable to wear, lightweight, stretchable and conform to the user. The glove was
first designed using a single sensor on each finger and thumb, and its performance
compared to a commercial data glove. While the commercial data glove is not a gold
standard for measuring joint angles it gave an indication that the textile sensor system could
be suitable for our application. Following on from this the glove design was improved
by adding additional sensors to differentiate between different finger positions. Testing
of this was carried out using Vicon motion capture to evaluate its performance in
controlled laboratory conditions. A graphical user interface was developed to guide
patients through prescribed exercises, providing motivation while also giving the option
of logging daily performance. The aim is to be able to monitor the patient’s level of
stiffness and range of motion throughout the day, away from the clinical setting, in
order to develop a personalised treatment for their condition.
2
2.1</p>
    </sec>
    <sec id="sec-2">
      <title>Methods</title>
      <sec id="sec-2-1">
        <title>Glove design</title>
        <p>A sensor glove has been developed using fabric stretch sensors integrated into an
oedema glove. It is important that the glove design does not restrict or influence
movement. The stretch sensors are made of a knit fabric coated with conducting polymer,
giving them piezoresistive properties. This means that when the fabric is stretched the
resistance changes, which can be measured using straightforward circuitry and captured
with a microprocessor platform. An Arduino Fio with integrated Xbee radio was used
to collect and wirelessly transfer the data to a laptop.</p>
        <p>Two glove designs are presented here. First a glove with five sensors was created
and tested (Design 1). After testing its performance, an improved design (Design 2)
was created which integrated more sensors to identify more specific finger movements.
Design 1 was a straightforward design using just one stretch sensor on each finger.
Each stretch sensor covered all three finger joints - the distal interphalangeal joint
(DIP), proximal inter-phalangeal joint (PIP) and metacarpal-phalangeal joint (MCP),
Fig. 1(b). Strips of sensor fabric of 5mm width were stitched in place using conductive
stainless steel thread, shown in Fig. 1(a). A circular sew-in prototype board (Lilypad
protoboard) was used to connect to the electronic circuitry. The sensor fabric and
conductive thread were covered using a lycra® fabric for protection and this layer also held
the sensor in place over the joints. The protoboard was encased with moulded silicone
(Sugru®) to secure the connections. The Arduino Fio and its Lithium Polymer battery
were housed in a 3D-printed custom fit enclosure designed to fit the curvature of the
wrist. A battery of 400mAh was chosen for its small size, providing an operation time
of approximately one hour continuous use. This was sufficient for initial tests based in
a laboratory setting with constant wireless data transmission. Longer term battery use
could be achieved using power optimization strategies e.g. integrating an SD card and
transmitting data when necessary.</p>
        <p>(a)
(b)</p>
        <p>DIP
PIP
MCP</p>
        <p>
          Design 1 may be sufficient for some applications, and is easier to manufacture, but due
to the nature of the sensors it cannot identify the location of the bend. Therefore the
second glove was designed to have more specific measurement of the position of each
joint. Two sensors were positioned on each finger – one covering DIP and PIP (these
joints tend to move together) and the other one covering MCP. A digital 3-axis
MPU6050 containing an accelerometer/gyroscope
          <xref ref-type="bibr" rid="ref9">(Sparkfun Electronics, 2012)</xref>
          was
included on the back of the hand (see Fig. 2(a)). The MPU-6050 contains a MEMS
accelerometer and a MEMS gyro in a single chip. It has a digital output and uses the I2C
interface for communication. A multiplexer (74HC4052) was used to expand the inputs
on the Arduino Fio board from six to twelve, allowing ten fabric sensor inputs and two
inputs for the MPU-6050. As with the first glove prototype the sensors were covered
using fabric and the wired connections reinforced using moulded silicone (Sugru®).
To connect to the user interface this glove was given Wi-Fi capability using a RN-XV
WiFly module
          <xref ref-type="bibr" rid="ref8">(Roving Networks, 2011)</xref>
          . This component provides wireless
communication with any device capable of receiving 802.11 b/g data. It contains built-in
applications for DHCP, DNS, Telnet, FTP and HTML. This interface can be attached
directly to any suitable device through an ad-hoc network, or can be configured to
attach to a network infrastructure by TKIP authentication and communicate using its
integrated TCP/IP communication stack. The Wi-Fi module is configured with an SSID,
TCP socket number, and static IP address. The SSID is broadcast from the Wi-Fi
module once the data glove is powered on. A local device capable of detecting the SSID
broadcast may connect to the Wi-Fi interface to create an ad-hoc network with the data
glove. The Wi-Fi module is configured using a static link-local
          <xref ref-type="bibr" rid="ref3">(Cheshire et al., 2005)</xref>
          IP address 169.254.1.1. A link-local address is suited to the typical operating
environment of the ad-hoc connection between data glove and connected device.
The graphical user interface developed by the School of Computing and Intelligent
Systems at Ulster University provides the motion capture software to regulate glove
functionality. This includes sensor calibration, sensor recording and playback,
alongside detailed statistical analysis of recorded movement to measure and evaluate
variance within exercise routines. The interface has been designed in collaboration with
target patient and clinician end-users in Altnagelvin Hospital in Co. Derry.
The custom software captures real-time data streamed from the data glove and
postprocesses it using software algorithms. The software also provides real-time user
feedback and analysis of exercise recordings for clinicians to assess. The bespoke software
records objective routines that are defined by the clinician and performed by the patient
at home at prescribed times throughout the day.
Fig. 3(a) shows a screen capture of the visual feedback window with a real-time hand
animation and detailed information on calculated joint angles. The 3D hand mimics
patient finger joint movement as detected by data glove sensors; therefore the hand
exercise routines completed remotely by the patient at home can be played back and
viewed by the clinician. Each routine is analysed by controlling software and
automatically partitioned into constituent repetitions. Each repetition is further subdivided and
provides timing information on flexion and extension movement as well as minimum
and maximum angular and velocity information calculated for each repetition. Fig. 4
shows one typical flexion and extension angular movement profile for a finger joint.
Individual flexion and extension movement is sigmoidal shaped as demonstrated by the
flexion and extension lines, and one complete open-closed hand movement produces a
Gaussian shaped curve. This information is used to provide indicators of changes in
movement kinetics between exercise routines. Information is presented to the clinician
as an assistive tool to aid with finger joint ROM assessment (see Fig. 3(b)). Colour
coding of each exercise routine visually identifies variation in patient movement. Such
information can help support the clinician during initial patient diagnosis and to
measure progression or decline throughout patient treatment.
        </p>
      </sec>
      <sec id="sec-2-2">
        <title>Glove design 1 - Comparison with 5DT data glove.</title>
        <p>
          The oedema fabric sensor glove has been compared to the 5DT Ultra 14 off-the-shelf
virtual reality glove to determine accuracy of ROM measurement. The 5DT glove is a
popular high-end commercial product that is representative of current state-of-the-art
data gloves
          <xref ref-type="bibr" rid="ref1">(5DT Data Glove, 2011)</xref>
          . Both gloves were calibrated using software
algorithms within the controlling software. Both gloves were then simultaneously worn on
the dominant right hand of a subject with 19.7cm hand size and were connected to
individual computers hosting identical copies of the controlling software system. An
exercise routine was configured on the controlling software that consisted of 12 flexion
and extension repetitions that measured movement of the middle MCP finger joint. The
first repetition was used to synchronise recordings between computers and to remove
unintentional delays in initial finger movement. Data was sampled every 25 ms from
both data gloves. The controlling software segmented data into constituent flexion and
extension movement.
        </p>
        <sec id="sec-2-2-1">
          <title>Hand extension</title>
        </sec>
        <sec id="sec-2-2-2">
          <title>Hand flexion: :</title>
        </sec>
      </sec>
      <sec id="sec-2-3">
        <title>Glove design 2 - Comparison with Vicon Nexus Motion system.</title>
        <p>
          A 12 camera Vicon Nexus system
          <xref ref-type="bibr" rid="ref11">(Vicon Motion Systems, 2013)</xref>
          was used as a gold
standard reference for testing the performance of the second glove prototype. This
procedure was carried out in collaboration with the School of Health &amp; Human
Performance at DCU. The Vicon system is generally used for larger range movements of the
body. The markers used were 12 mm diameter and the cameras covered a space of 5m
x 5m. The subject sat on a chair and raised their hand above their head and away from
the body to reduce the risks of occlusion and inaccuracy of the Vicon system. Testing
focused on a single finger at a time as placement of markers on every finger joint caused
reading inaccuracies by marker-ghosting. Markers were placed on the flat part of the
joint as placing them directly on top of the joint caused too much movement of each
marker and affected angular accuracy. Three markers were used to study an individual
joint in each trial. Fig. 6 shows the placement of markers for studying the middle finger
MCP joint and Fig. 7 shows the placement of markers for studying the middle finger
PIP joint.
        </p>
        <p>(a)
(b)</p>
      </sec>
      <sec id="sec-2-4">
        <title>Study 1 – Textile sensor glove 1 compared with 5DT data glove.</title>
        <p>Initial results demonstrate a high correlation (r = 0.96) of recorded angular movement
between the oedema fabric sensor glove and 5DT virtual reality glove. Fig. 8 shows a
comparison of the recorded angular and velocity movements from the two gloves
during a single flexion/extension movement. These are results captured from the middle
finger MCP joint.</p>
        <p>The minimum and maximum angular measurements for the middle finger MCP joint
were averaged across the twelve repetitions, for each glove. Fig. 9 illustrates these
results. The average minimum angle during hand flexion for the textile glove was 7.9º
(standard deviation of 0.5º) and for the 5DT glove was 3.9º (standard deviation of 1.1º).
The maximum angle during hand extension for the textile glove was 72.97º (standard
deviation of 1.17º) and for the 5DT glove was 87.94º (standard deviation of 1.68º). The
minimum angle would ideally be 0 º and the maximum 90 º. A gold standard system
such as Vicon is needed to verify the actual value of the angle as the 5DT glove is not
a gold standard system. Fig. 10 shows the average timings of the hand movements, the
sustain time is the time between hand flexion and extension, as illustrated in Fig 4.</p>
      </sec>
      <sec id="sec-2-5">
        <title>Study 2 – Textile sensor glove 2 compared with Vicon Nexus Motion system.</title>
        <p>To analyse the Vicon data the distance between each marker was calculated to give 3
sides of a triangle. Then the cosine rule was used to determine the internal angle which
corresponds to the joint under analysis. The measurements for movements of the hand
from full extension to full flexion are shown in Fig. 11 and Fig. 12. At the start of data
collection the hand was held closed for 5 seconds to synchronise the data. Fig. 11 shows
movement of the PIP joint for three flexion/extension actions. The glove sensor shows
repeatable measurements for this, correlating to the Vicon measurements. There is a
lag in the time response of the fabric sensors, before reaching the maximum value there
is approximately a 2 second delay with the glove fabric sensor. Fig. 12 shows the
measurements taken during the middle finger MCP trial. Six hand flexion/extension actions
were performed, the first held for 5 seconds at the start. Measurements from this first
exercise were used to calibrate the glove data for the following five exercises. The
average error based on the maximum and minimum measurements was ±10.7º.
30
32
34
36
40
42
44</p>
        <p>46
In the first part of the study the textile sensor glove shows similar performance to the
5DT commercial data glove and therefore shows potential for a home monitoring
wearable system. The textile glove has the advantage of being comfortable to wear and
suitable for wearing in cases of impaired dexterity. To evaluate the accuracy of the
textile sensor glove testing with Vicon was carried out in the lab setting. While there is
error of up to 10º and a small latency in the textile sensor signals the glove may be
useful in monitoring day to day flexibility and range of movement. Gold standard
systems such as the Vicon Nexus Motion system used in this study are very expensive and
not practical for everyday use by patients.</p>
        <p>
          The sensors may also be integrated into other smart garments to monitor other joints to
provide long-term measures and trend analysis of the patient’s condition in the home
setting. Such objective measurements would reduce dependence on patient memory
and provide the clinician with accurate information for better and targeted care
proposals. This information may help the patient and the clinician to understanding the
individual condition and assist in disease management. Combined with a user interface
to motivate users a personalised care and treatment plan may be formulated. Shorter
patient analysis times also would enhance patient care through increased possibilities
for clinician-patient interaction. A glove that fits the user may help analyse trends and
daily variance in flexibility and mobility. Improving sensor accuracy could address
problems of traditional inter-tester and intra-tester reliability of finger joint
measurement
          <xref ref-type="bibr" rid="ref5">(Lewis et al., 2010)</xref>
          using current measurement systems.
        </p>
        <p>A smart glove was designed with a focus on fit and comfort for the wearer. In this
work the sensors and the glove itself are made from a Lycra® material. Conventional
bend sensors and fibre optics typically used in computer gaming and motion capture
gloves tend to be more rigid. These are not ideal for use in people with impaired
dexterity and mobility as to enhance uptake and use the glove must be straightforward to
put on and must also not restrict movement. Textile sensors may be integrated into
support garments such as knee support sleeves, which may already be worn to help
alleviate an injury. The ideal strategy therefore is to provide additional functionality to
such medical textiles. An oedema glove was used in this work as an initial motivation
for the glove development was for another application in stroke rehabilitation, where
patients would often wear oedema gloves to reduce swelling, and compression gloves
are often use in arthritis also. A key to the success of wearable technology is to build
on garments that are already being worn and to seamlessly integrate the sensing
technology technology into the garment. Recent developments in flexible circuitry and
stretchable conductive inks will help the integration of fabric sensors in this way.
5</p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>Conclusions</title>
      <p>Initial comparative testing between the oedema fabric sensor glove and 5DT virtual
reality glove demonstrate high levels of correlation. This achievement exhibits the
gloves capabilities when compared to a commercial state-of-the-art glove product.
Further testing is needed with a Vicon system that is set up with smaller markers and using
cameras in a closer range. Initial results show repeatable measurements using the glove
compared to Vicon. Long-term testing to ensure reproducibility and robustness of
design is also required.</p>
      <p>This project is a multidisciplinary effort, involving expertise in material science and
functional design, computer science, human health and performance, and influenced by
the end user needs. The aim is to have a better understanding of joint stiffness by
monitoring dynamic movements of the hand at different times of the day. This quantifiable
information can be measured offline from the clinic. The controlling software manages
user access throughout each exercise recording. It controls data glove functionality for
accurate, reliable and repeatable measurement of joint movement to determine
limitation and variance throughout each day of measurement. Having such information can
help to develop a personalised approach to management and treatment of various
chronic conditions.</p>
      <sec id="sec-3-1">
        <title>Acknowledments</title>
        <p>End-user advice and input provided by Dr. Philip Gardiner Altnagelvin Hospital,
Western Health and Social Care Trust, Derry
This work was funded by Science Foundation Ireland under the INSIGHT initiative,
grant SFI/12/RC/2289 (INSIGHT)</p>
      </sec>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          1. 5DT Data
          <string-name>
            <surname>Glove</surname>
          </string-name>
          (
          <year>2011</year>
          )
          <article-title>5DT Data Glove 14 Ultra [WWW Document]</article-title>
          . URL http://www.5dt.com/products/pdataglove14.
          <source>html (accessed 1.10.12).</source>
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          2.
          <string-name>
            <surname>Castano</surname>
            ,
            <given-names>L. M.</given-names>
          </string-name>
          &amp;
          <string-name>
            <surname>Flatau</surname>
            ,
            <given-names>A. B.</given-names>
          </string-name>
          (
          <year>2014</year>
          )
          <article-title>Smart fabric sensors and e-textile technologies: a review</article-title>
          .
          <source>Smart Materials and Structures</source>
          , vol.
          <volume>23</volume>
          , no., pp.
          <fpage>1</fpage>
          -
          <lpage>27</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref3">
        <mixed-citation>
          3.
          <string-name>
            <surname>Cheshire</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Aboba</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          &amp;
          <string-name>
            <surname>Guttman</surname>
            ,
            <given-names>E.</given-names>
          </string-name>
          (
          <year>2005</year>
          )
          <article-title>Dynamic Configuration of IPv4 Link-Local Addresses</article-title>
          .,
          <string-name>
            <surname>Apple</surname>
            <given-names>Computer</given-names>
          </string-name>
          , Microsoft Corporation, Sun Microsystems, .
        </mixed-citation>
      </ref>
      <ref id="ref4">
        <mixed-citation>
          4.
          <string-name>
            <surname>Coyle</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Curto</surname>
            ,
            <given-names>V. F.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Benito-Lopez</surname>
            ,
            <given-names>F.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Florea</surname>
            ,
            <given-names>L.</given-names>
          </string-name>
          &amp;
          <string-name>
            <surname>Diamond</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          (
          <year>2014</year>
          )
          <article-title>Wearable Bio and Chemical Sensors</article-title>
          . IN SAZONOV, E. &amp;
          <string-name>
            <surname>NEUMAN</surname>
            ,
            <given-names>M. R</given-names>
          </string-name>
          . (Eds.) Wearable Sensors, Fundamentals, Implementation and Applications.
        </mixed-citation>
      </ref>
      <ref id="ref5">
        <mixed-citation>
          5.
          <string-name>
            <surname>Lewis</surname>
            ,
            <given-names>E.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Fors</surname>
            ,
            <given-names>L.</given-names>
          </string-name>
          &amp;
          <string-name>
            <surname>Tharion</surname>
            ,
            <given-names>W. J.</given-names>
          </string-name>
          (
          <year>2010</year>
          )
          <article-title>Interrater and intrarater reliability of finger goniometrie measurements</article-title>
          . .
          <source>Am. J. Occup. Ther.</source>
          , vol.
          <volume>64</volume>
          , no., pp.
          <fpage>555</fpage>
          -
          <lpage>561</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref6">
        <mixed-citation>
          6.
          <string-name>
            <given-names>National</given-names>
            <surname>Collaborating</surname>
          </string-name>
          <article-title>Centre for Chronic Conditions (UK) (2009) Rheumatoid Arthritis,National Clinical Guideline for Management and Treatment in Adults, NICE Clinical Guidelines</article-title>
          , No.
          <fpage>79</fpage>
          . London: Royal College of Physicians (UK),.
        </mixed-citation>
      </ref>
      <ref id="ref7">
        <mixed-citation>
          7.
          <string-name>
            <given-names>O</given-names>
            <surname>'Quigley</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            ,
            <surname>Sabourin</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            ,
            <surname>Coyle</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            ,
            <surname>Connolly</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            ,
            <surname>Condall</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            ,
            <surname>Curran</surname>
          </string-name>
          ,
          <string-name>
            <given-names>K.</given-names>
            ,
            <surname>Corcoran</surname>
          </string-name>
          ,
          <string-name>
            <given-names>B.</given-names>
            &amp;
            <surname>Diamond</surname>
          </string-name>
          ,
          <string-name>
            <surname>D.</surname>
          </string-name>
          (
          <year>2014</year>
          )
          <article-title>Characteristics of a Piezo-Resistive Fabric Stretch Sensor Glove for Home-Monitoring of Rheumatoid Arthritis</article-title>
          .
          <source>11th International Conference on Wearable and Implantable Body Sensor Networks Zurich.</source>
        </mixed-citation>
      </ref>
      <ref id="ref8">
        <mixed-citation>
          8.
          <string-name>
            <given-names>Roving</given-names>
            <surname>Networks</surname>
          </string-name>
          (
          <year>2011</year>
          )
          <article-title>RN-XV Data Sheet</article-title>
          . Roving networks,
          <source>California</source>
          . vol., no., pp.
        </mixed-citation>
      </ref>
      <ref id="ref9">
        <mixed-citation>
          9.
          <string-name>
            <given-names>Sparkfun</given-names>
            <surname>Electronics</surname>
          </string-name>
          (
          <year>2012</year>
          )
          <article-title>Triple Axis Accelerometer and Gyro Breakout - MPU-6050 [WWW Document]</article-title>
          . URL https://www.sparkfun.com/products/11028. vol., no., pp.
        </mixed-citation>
      </ref>
      <ref id="ref10">
        <mixed-citation>
          10.
          <string-name>
            <surname>Stoppa</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          &amp;
          <string-name>
            <surname>Chiolerio</surname>
            ,
            <given-names>a. A.</given-names>
          </string-name>
          (
          <year>2014</year>
          )
          <article-title>Wearable Electronics and Smart Textiles: A Critical Review</article-title>
          .
          <source>Sensors</source>
          , vol.
          <volume>14</volume>
          , no., pp.
          <fpage>11957</fpage>
          -
          <lpage>11992</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref11">
        <mixed-citation>
          11.
          <string-name>
            <surname>Vicon Motion Systems</surname>
          </string-name>
          (
          <year>2013</year>
          )
          <article-title>Vicon [WWW Document]</article-title>
          . URL http://www.vicon.com/.
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>