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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Preliminary Experimental Analysis of Reservoir Computing Approach for Balance Assessment</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Claudio Gallicchio</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Alessio Micheli</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Luca Pedrelli</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Federico Vozzi</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Oberdan Parodi</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Department of Computer Science, University of Pisa</institution>
          ,
          <addr-line>Largo B. Pontecorvo 3, Pisa</addr-line>
          ,
          <country country="IT">Italy</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>IFC-CNR Pisa</institution>
          ,
          <addr-line>Via Moruzzi 1, Pisa</addr-line>
          ,
          <country country="IT">Italy</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2015</year>
      </pub-date>
      <abstract>
        <p>Evaluation of balance stability in elderly people is of prominent relevance in the eld of health monitoring. Recently, the use of Wii Balance Board has been proposed as valid alternative to clinical balance tests, such as the widely used Berg Balance Scale (BBS) test, allowing to measure and analyze static features such as the duration or the speed of assessment of patients' center of pressure. In an innovative way, in this paper we propose to take into consideration the whole temporal information generated by the balance board, analyzing it by means of dynamical neural networks. In particular, using Recurrent Neural Networks implemented according to the Reservoir Computing paradigm, we propose to estimate the BBS score from the temporal data generated by the execution of one simple exercise on the balance board. Preliminary experimental assessments of the proposed approach on a real-world dataset show promising results.</p>
      </abstract>
      <kwd-group>
        <kwd>Reservoir Computing</kwd>
        <kwd>Learning with Temporal Data</kwd>
        <kwd>Balance Assessment</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>
        A sedentary lifestyle is a risk factor for the development of many chronic illnesses.
The common physiological aging causes a decrease of global functional abilities:
one of the most important is balance disorder [
        <xref ref-type="bibr" rid="ref16">16</xref>
        ]. The control of balance is
complex, with a strong integration and coordination of multiple body elements
including visual, auditor and motor systems [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ]. A comprehensive clinical
assessment of balance is important for both diagnostic and therapeutic reasons
in clinical practice [
        <xref ref-type="bibr" rid="ref17 ref4">4, 17</xref>
        ]. The Berg Balance Scale (BBS) test is considered the
gold standard assessment of balance with small intra-inter rater feasibility and
good internal validity. The work in [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ] assessed the validity of the BBS by
examining how scale scores are related to clinical judgments, laboratory measures
of postural sway and external criteria re ecting balancing ability. Furthermore,
scores could predict falls in the elderly, and how they are related to motor and
functional performance in stroke patients. The Berg's utility includes grading
di erent patients' balance abilities, monitoring functional balance over time and
evaluating patients responses to di erent protocols of treatment [
        <xref ref-type="bibr" rid="ref18">18</xref>
        ]. Based on
a test of 14 exercises/items, BBS is performance-based and has a scale of 0-4
Copyright c 2015 for this paper by its authors. Copying permitted for private and academic
purposes.
(clinician assigned) score for each item, with a maximum overall score of 56.
Within the scopes of the DOREMI European project (GA 611650), a
technological platform to support and motivate older people to perform physical activity
is under development, aiming at reducing sedentariness, cognitive decline and
malnutrition, promoting an improvement of quality of life and social inclusion.
One of the element of DOREMI platform is a smart carpet, based on the use of
Nintendo Wii Balance Board (WBB), able to gather information pertaining to
users' weight distribution at the four corners of the board. Such tool allows to
design an automatic system for balance assessment through the daily repetition
of one simple BBS exercise. This type of analysis, done by users at medical
facilities or, remotely, at their own houses, can help clinicians in the evaluation of
older people equilibrium and in control of its evolution.
      </p>
      <p>
        The use of the WBB is motivated by the fact that it represents a low-cost and
portable tool, recently successfully adopted for problems related to standing
posture correction [
        <xref ref-type="bibr" rid="ref14">14</xref>
        ] and for training standing balance in the elderly [
        <xref ref-type="bibr" rid="ref19">19</xref>
        ].
Interestingly, the WBB has been validated in comparison with gold standard force
platforms [
        <xref ref-type="bibr" rid="ref13">13</xref>
        ] in its reliability to track users' balance parameters, such as the
center of pressure path length and velocity [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ]. However, it is worth to observe that
the whole signal time-series generated by the WBB potentially contains a richer
information than such static parameters. Thereby, in this paper we propose to
analyze the data generated by WBB using Recurrent Neural Networks (RNNs),
which are learning models suitable for catching and processing dynamic
knowledge from noisy temporal information. In particular, we considered the problem
of estimating the BSS score of a patient using in input the temporal
information generated by the execution of one simple BBS exercise on the WBB. This
approach potentially allows to avoid the need to repeat all the 14 BBS exercises
for new patients. An alternative approach in [
        <xref ref-type="bibr" rid="ref15">15</xref>
        ] tries to estimate the BBS score
of a patient using information extracted from a tri-axial accelerometer placed on
the lower back during the execution of some items of the BBS. Such approach,
however, adopts a solution which is more intrusive for the patient. At the best
of our knowledge, our work represents the rst attempt at estimating the BBS
score directly from the temporal data generated while the patient performs a
simple balance exercise in an non-intrusive way using an external device.
2
      </p>
    </sec>
    <sec id="sec-2">
      <title>Balance Assessment with RC</title>
      <p>
        A measurement campaign has been conducted on 21 volunteers, aged between
65 and 80 years. We measured the weight signal produced by the WBB at the 4
corners of the board sampled at 5 Hz during the execution of the exercise # 10
in the BBS test, i.e. turn to look behind, selected for its simple execution and
short duration ( 10 seconds). To take into account for possible variations in the
exercise executions, for each patient we recorded data from a number of
maximum 10 repetitions of the exercise. We therefore obtained a Balance dataset for
a regression task on sequences, containing couples of the type (s; ytg), where s is
the 4-dimensional input sequence of users' weight values recorded by the WBB
during the exercise and ytg is the target BBS score (over all the 14 exercises)
of the corresponding patient, representing the ground-truth evaluated by a
clinician during the campaign. For performance assessment we adopted the Mean
Absolute Error (MAE) of the BBS score estimation provided by the learning
models. It is worth noticing that the Balance dataset contains an outlier patient
with BBS score of 24, which has been discarded for performance evaluation.
We model the dynamics of the temporal data involved by the balance evaluation
task by dynamical neural networks models within the class of RNNs. In
particular, we adopt the Reservoir Computing (RC) approach [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ] for RNN modeling,
and take into consideration the Leaky Integration Echo State Network (LI-ESN)
[
        <xref ref-type="bibr" rid="ref10 ref11">11, 10</xref>
        ], a state-of-the-art model for e cient learning in sequential/temporal
domains, which has proved to be particularly suitable in dealing with the nature of
the input data originated from sensors [
        <xref ref-type="bibr" rid="ref1 ref2">1, 2</xref>
        ]. LI-ESNs implement discrete time
dynamical systems, and consist of two main components, a dynamical reservoir,
which realizes a recurrent encoding of the input history and provides the system
with a memory of the past [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ], and a static readout which computes the output. A
LI-ESN is composed of an input layer with NU units, a recurrent non-linear
reservoir layer with NR sparsely connected units, and a linear readout layer with NY
units. At each time step t, the reservoir computes a state x(t) 2 RNR according
to a state transition function x(t) = (1 a)x(t 1)+a tanh(Winu(t)+W^ x(t 1)),
where u(t) 2 RNU is the input at time step t, Win 2 RNR NU is the
input-toreservoir weight matrix, W^ 2 RNR NR is the recurrent reservoir weight matrix,
and a 2 [0; 1] is the leaking rate parameter that controls the speed of the reservoir
dynamics [
        <xref ref-type="bibr" rid="ref11 ref12">11, 12</xref>
        ]. For sequence-to-element regression tasks in which an output
value is required in correspondence of an entire input sequence, the use of a mean
state mapping function has proved to be e ective [
        <xref ref-type="bibr" rid="ref7 ref8">7, 8</xref>
        ]. Accordingly, given an
input sequence of length n, s = [u(1); : : : ; u(n)], we average the state activation
over the steps of the input sequence, i.e. (s) = n1 Pn
is applied to compute the output of the model y(s)
2t=R1NxY(tb).yTahleinn,eatrhecormeabdionuattion of the elements in (s), i.e. y(s) = Wout (s), where Wout 2 RNY NR is the
readout-to-reservoir weight matrix. The readout is the only LI-ESN component
that is trained, typically by e cient linear methods, e.g. pseudo-inversion and
ridge regression [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ]. The reservoir is left untrained after initialization under the
constraints of the echo state property (ESP) [
        <xref ref-type="bibr" rid="ref10 ref12 ref6">10, 12, 6</xref>
        ]. A reservoir initialization
condition related to the spectral radius of W^ is often used in literature and is
adopted in this paper, i.e. ((1 a)I + aW^ )) &lt; 1 (see e.g. [
        <xref ref-type="bibr" rid="ref12 ref6">12, 6</xref>
        ] for details).
3
      </p>
    </sec>
    <sec id="sec-3">
      <title>Experimental Results</title>
      <p>
        The experimental analysis presented in this paper aimed at preliminarily
assessing the generalization performance of the proposed RC approach. At the same
time, in order to reduce the patients' e ort for future data gathering campaigns,
we were also interested in empirically analyzing the trade-o between the number
of exercise repetitions for each patient required for training and the predictive
performance that can be achieved. Accordingly, we took into consideration two
experimental settings. In the rst experimental setting, the Balance dataset was
split in a training set, containing data from 17 patients ( 80% of the total), and
an external test set for performance assessment, containing data from 4 patients
( 20% of the total, chosen in order to represent a uniform sampling in the range
of possible BBS target values). We considered LI-ESNs with reservoir dimension
in NR 2 f100; 200; 500g, 10% of reservoir units connectivity, leaky parameter
a 2 f0:1; 0:3; 0:5; 0:7; 1g and spectral radius = 0:99. For each reservoir
hyperparametrization, we independently generated 5 reservoir guesses, averaging the
results over such guesses. For readout training we used pseudo-inversion and
ridge regression with regularization r 2 f10; 1; 0:7; 0:5; 0:3; 0:1; 0:01; 0:001g. The
values of the reservoir hyper-parameters and readout regularization were chosen
by model selection, adopting a 4-fold cross validation scheme over the training
set. The selected LI-ESN resulted in a very good predictive performance, with a
test MAE of 4:25 0:39, which outperforms the results in [
        <xref ref-type="bibr" rid="ref15">15</xref>
        ] for patients within
a corresponding age range. Such results appear promising, also considering the
tolerance in the ground-truth data due to human observations. Moreover, we
observed that the test error is higher for patients with lower BBS target scores,
which correspond to a less sampled region in the input space.
      </p>
      <p>We also conducted a preliminary empirical investigation in order to evaluate
how the performance of the proposed LI-ESN approach scales with the number
of available training data for each patient. Accordingly, we uniformly split the
Balance dataset into groups containing sequences pertaining to 3 patients each,
according to a 7-fold cross validation scheme, progressively reducing the number
of training sequences for each patient. For this second experimental setting, we
restricted to the case of LI-ESNs with NR = 100 reservoir units, whereas all
the others reservoir hyper-parameters and readout regularization values were
selected (for each fold) on the validation set, considering the same range of values
as in the case of the rst experimental setting. Fig. 1 shows the MAE achieved
by LI-ESNs on the validation set, for decreasing number of available training
sequences. Results show that the validation performance is approximately stable
for a number of training sequences per patient in the range of 10-4, while it gets
rapidly worse as less than 4 training sequences per patient are used.
4</p>
    </sec>
    <sec id="sec-4">
      <title>Conclusions</title>
      <p>We have proposed an approach for assessing the balance abilities of elderly
people based on RC networks, used for temporal processing of data recorded by a
WBB during the execution of a simple BBS exercise, with the major advantage
of automatically evaluating the BBS score using only 1 of the 14 exercises. The
preliminary experimental analysis on a real-world dataset showed that our
approach is able to achieve a very good predictive performance, up to 4 points
of discrepancy in the BBS score with respect to the gold standard, which is good
also considering both the use of a single BBS item and the tolerance typical of
any subjective assessment scale. Overall, the possibility to infer the BBS scores
with a good performance starting from the signal of a single BBS exercise shows
the potentiality of our idea of exploiting the entire curve of the signal stream as
a rich source of information for the evaluation of balance assessment. We also
addressed the problem of evaluating the trade-o between the predictive
performance and the number of exercise repetitions required for training the RC
networks. A moderate number of repetitions in the training set turned out to be
already su cient for achieving a good performance. This aspect is of particular
interest in view of minimizing the e ort required for the collection of an adequate
and su ciently sampled dataset for balance estimation, as the repeated
execution of BBS exercises by elderly people could be onerous. The results illustrated
in this preliminary study have a potential utility by themselves, for the
development of a balance estimation tool, and they will be eventually exploited within
the purposes of the DOREMI project as a part of a larger health monitoring
system aiming at improving elderly quality of life and active aging.
Acknowledgments. The work was funded by a grant from DOREMI project
(FP7-ICT-2013, GA no. 611650). We would like to acknowledge Dr. Sara
Lanzisera, Dr. Cristina Laddaga (ASL5, Pisa), Dr. Andrea Bemi (Istituto Superiore di
Istruzione C. Piaggia, Viareggio) and Dr. Franca Giugni (CNR-IFC) for their
valuable inputs, support and e ort during the preparation and execution of tests,
and Dr. Luigi Fortunati, Dr. Filippo Palumbo and Dr. Erina Ferro (CNR-ISTI)
also for the realization of the middleware. We would also like to acknowledge all
the test participants for their support and active participation in these activities.</p>
    </sec>
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