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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>New York City, USA, July</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>A Hybrid Approach based Sentiment Extraction from Medical Contexts</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Anupam Mondal</string-name>
          <email>1anupam@sentic.net</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Ranjan Satapathy</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Dipankar Das</string-name>
          <email>1ddas@cse.jdvu.ac.in</email>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Sivaji Bandyopadhyay</string-name>
          <email>1sbandyopadhyay@cse.jdvu.ac.in</email>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>School of Computer and Information Sciences, University of Hyderabad</institution>
          ,
          <country country="IN">India</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2016</year>
      </pub-date>
      <volume>10</volume>
      <issue>2016</issue>
      <fpage>35</fpage>
      <lpage>40</lpage>
      <abstract>
        <p>In the domain of Bio medical Natural Language Processing (Bio-NLP), the information extraction and context sentiment identification are treated as emerging tasks. Several linguistic features like negation, uni-gram, bi-gram, Part-of-Speech (POS) have been used to extract the medical concepts and their sense-based context level information. Thus, in the present attempt, a hybrid approach which is the combination of both linguistic and machine learning approaches has been introduced to extract the contextual sense-based information from a medical corpus. The extraction of sentiment oriented keywords is the crucial part towards identifying the senses of medical contexts. In our previous work, we have developed a medical sense-based lexicon known as WordNet of Medical Event (WME). Several sentiment lexicons like SentiWordNet, SenticNet etc. were used to represent WME. In contrast, one of our primary motivations here is to build a sentiment extraction model based on medical contexts to leverage the knowledge of WME using a hybrid approach. The developed model is based on two phases, namely preprocessing phase and learning phase. The preprocessing phase is responsible for extracting and preparing structural data from the raw contexts whereas the learning phase helps to identify the sentiment patterns and evaluate the sentiment extraction process. The two phased hybrid model provides us 81% accuracy for extracting the sentiment based medical contexts as positive and negative by employing NaïveBayes and Sequential minimal optimization (SMO) supervised classifiers.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>One of the major objectives of Sentiment Analysis is to
identify and extract the subjective information from a given
text using rule based or machine learning approaches
[Cambria, 2016]. The domain specific knowledge with above
mentioned approaches help us to extract the contextual
sentiment information from the medical corpus. Due to lack of
involvement of domain experts and unavailability of domain
specific structured corpus, the task is challenging in
BioNLP domain. To overcome the scarcity of such domain
specific knowledge for sentiment analysis, several lexicons
have been developed like Medical Event Net (MEN),
Medical Fact Net (MFN), Medical Belief Net (MBN) and
WordNet of Medical Event (WME) [Cambria et al., 2010]. These
lexicons help to extract the sense of a medical concept, fact
and belief oriented information. The present paper reports
the development of a medical context based sentiment
extraction model. Hence, one of our primary aims is to
identify the sense-based concepts from the medical contexts and
extract their related sentiment features. In order to identify
the sense-based medical concepts, we have introduced the
current version of WordNet of Medical Event (WME2.0)
knowledge base. WME2.0 contains the medical concept
information with their related linguistic and sense-oriented
features like POS, gloss of the concept, semantics, polarity
score, affinity score, gravity score and sense(s). Among all
these features, we have only considered the sense-based
features like semantics, polarity score, affinity score and
sense to develop our present sentiment extraction model
[Swaminathan et al., 2010]. On the top of extracted medical
concepts based on WME2.0 lexicon, we have applied
linguistic and machine learning approaches to get the final
sentiment of the contexts. The linguistic approach helps to
manage the negation of the contexts as well as derive new
rules to extract the sense(s) of such contexts. The POS,
unigram, bi-gram, affinity score, polarity score and sense
features of the medical concepts of WME2.0 help to extract the
sentiment of the medical contexts. The supervised machine
learning approach has been introduced to verify the
contextual sentiment extracted using linguistic approach. In the
process, we have applied NaïveBayes and Sequential
minimal optimization (SMO) supervised machine learning
classifiers on the derived linguistic features.</p>
      <p>In the paper, we have incorporated both linguistic and
machine learning approaches together as a hybrid model to
leverage the sentiment oriented knowledge of both the
domain [Villena-Romn et al., 2011]. The proposed hybrid
model follows two phase architecture namely
preprocessing phase and learning phase. In pre-processing
phase, we have focused on the preparation of structured
medical concepts from the raw medical contexts and the
learning phase helps to extract the sentiment of such
contexts and evaluate them. The two phase model generates the
output in the form of positive or negative sentiment of the
context. The hybrid approach based learning phase provides
81% accuracy to extract the medical context based
sentiment information.</p>
      <p>The remainder of the paper is structured as follows,
Section 2 presents related work followed by model design
describing the pre-processing and learning phases in Section 3.
Section 4 talks about the model discussion and evaluation
process we have followed in the paper. Finally, in Section 5,
we present our conclusion and future scopes of the model.
2</p>
    </sec>
    <sec id="sec-2">
      <title>Related Work</title>
      <p>Sentiment analysis of medical contexts is contributory and
growing research field under Bio-NLP domain [Cambria et
al., 2013]. A large number of unstructured corpora and lack
of domain experts’ involvement have introduced more
challenge in this task. In the process, the researchers focused on
developing medical sentiment-based lexicon to identify the
sentiments of medical concepts. Therefore, the medical
concepts and their sense based features indeed help to identify
the sentiment of the medical contexts. The linguistic,
machine learning and hybrid approaches have been introduced
to build the concept and context based sentiment extraction
systems. The linguistic approach helps to find the negation
words, phrases and construct the knowledge-based rules
(with unigram, bigram and n-gram features) for the context
level sentiment extraction [Elkin et al., 2005; Niu et al.,
2005; Szarvas et al., 2008]. Smith and Fellbaum, 2004
developed a Medical Word-Net (MEN) along with two
subnetworks, namely Medical FactNet (MFN) and Medical
BeliefNet (MBN), for the evaluation of consumer health
reports [Smith and Fellbaum, 2004]. MEN was developed
with the help of formal architecture of the Princeton
WordNet [Fellbaum, 1998]. MFN serves to assist the non-expert
group in providing a better understanding of basic medical
information. MBN identifies beliefs about the medical
phenomenon. Their primary motivation was to develop a
network of medical information retrieval systems with
visualization effect. The domain-specific knowledge and the
abovementioned features are essential to improve the
efficiency of the sentiment extraction system [Shukla et al.,
2015]. So, these approaches were not able to provide
adequate accuracy due to the lack of knowledge involvement
from the domain experts. Hence, to overcome the mentioned
problem, the researchers introduced supervised machine
learning approaches [Smith and Lee, 2012]. Standard
NaïveBayes, Multinomial NaïveBayes and Support Vector
Machine (SVM) supervised classifiers were applied with
unigram, bigram, Parts Of Speech (POS) and negation
features under the machine learning framework. The
researchers have also used hybrid approaches to improve the
accuracy of the medical context based sentiment extraction
systems. One of the hybrid approaches was developed with the
combination of linguistic and machine learning approaches
[Boytcheva et al., 2005; Villena-Romn et al., 2011]. Sohn et
al., 2012, developed an emotion identification system from
suicide notes using the hybrid approach [Sohn et al., 2012].
The suicide notes were provided by the challenge organizers
of Informatics for Integrating Biology and the Bedside
(I2B2). Machine learning, linguistic rule-based and their
combined approaches have been applied to the training
dataset of the suicide notes and the system provided 0.5640
micro-average F-score for the training dataset. Birks et al.,
2009, applied the combination of RIPPER (Repeated
Incremental Pruning to Produce Error Reduction), multinomial
NaïveBayes classifier and manual pattern matching rules
to identify the emotions of the sentences [Birks et al., 2009].
Mondal et al., 2016, developed WordNet of Medical Events
(WME) lexicon to identify the medical concepts and their
knowledge-based and semantic features using hybrid
approach [Mondal et al., 2015]. The latest version of WME
(WME2.0) contains POS, semantics, gloss, affinity score,
gravity score, polarity score and sense features of the
concepts [Mondal et al., 2016]. WME2.0 sentiment lexicon has
identified the senses of the concepts using SentiWordNet1,
SenticNet2, BingLiu3 and Taboda’s adjective list [Mondal et
al., 2016; Mondal et al., 2015; Taboada et al., 2011]. In this
paper, we have used the WME2.0 lexicon to identify the
concepts and their features to extract sentiments of the
medical contexts.</p>
    </sec>
    <sec id="sec-3">
      <title>Model Design</title>
      <p>The knowledge-based sentiment lexicon is crucial to design
a context based sentiment extraction system. The medical
concepts and their linguistic features are extracted from the
domain-specific sentiment lexicon. To overcome the
problem of experts’ availability, we have formulated WME2.0
lexicon with a hybrid approach. It adds an extra dimension
1 http://sentiwordnet.isti.cnr.it/
2 http://sentic.net/
3 https://www.cs.uic.edu/liub/FBS/sentiment-analysis.html
for improving the accuracy of the extracted medical context
sentiment. The proposed hybrid approach is the combination
of linguistic and machine learning approach. The approach
consists of two phases namely pre-processing and learning
phase. Figure 1 shows the architecture of the proposed
approach (model).</p>
    </sec>
    <sec id="sec-4">
      <title>3.1 Pre-processing phase</title>
      <p>The phase extracts the sentiments of medical contexts in the
form of context related medical concepts, their sentiments
and knowledge-based information. The structured form of
the concepts is essential in identifying the important medical
concepts from the context.
In this concern, to represent the structured medical concepts,
the required steps are data extraction, cleansing and
formatting. The research community provided various linguistic
resources such as open source data preprocessing tools (viz.
NLTK, stemming etc.) [Na et al., 2012]. The following
steps illustrate the basic operations of the pre-processing
phase:
Data Extraction: The medical concepts extraction from a
given context is the primary task of this step. WME2.0 helps
to extract the medical concepts and their linguistic and
sense-based features from the context. Moreover, the
nonmedical concepts and their sense identification are also
essential to identify the sentiment of the context. The
nonmedical concepts the senses have been extracted using
SentiWordNet and SenticNet lexicons [Cambria et al., 2014;
Cambria et al., 2013; Esuli and Sebastiani, 2006].
Data Cleansing: Data cleansing step is responsible to
remove the context related stop-words and stemmed the
concept words. The classification of medical and nonmedical
concepts and identification of negation words (like no, not,
never etc.) are also taken care of by data cleansing step
[Huang and Lowe, 2007].</p>
      <p>Data Formatting: Data formatting has been applied to
represent the structured form of the extracted medical concepts
[Hussain et al., 2011]. The extracted structured (vector)
concepts have been forwarded to the learning phase along
with their features. The concept structure is represented as
follows:
&lt;Concept (gastric), POS (noun), Semantics (abdominal
breathing, visceral, intestinal, belly, duodenal, stomachic),
Polarity Score (-0.5), Sense (Negative)&gt;
3.2</p>
    </sec>
    <sec id="sec-5">
      <title>Learning phase</title>
      <p>Followed by the pre-processing phase, the hybrid approach
has been introduced in the learning phase to build the
contextual sentiment extraction system. Linguistic and machine
learning has been combined to form the hybrid approach.
The linguistic approach with WME2.0 knowledge base
lexicon helps to identify the hidden rules. These rules are able
to extract the concept sentiment and their polarity. The
extracted linguistic concept features (rules) were fed to the
supervised machine learning classifiers to evaluate the
accuracy of the model. The linguistic approach provides a
support to handle the negation effect of the context and help to
identify the appropriate sentiment of the context [Huang and
Lowe, 2007]. The learning phase is illustrated as follows:
Step 1: Identify the polarity score and sense of each concept
(medical and non-medical) of the context.</p>
      <p>Step 2: Linguistic approach-based negation words (concept)
handling.</p>
      <p>Step 3: Calculate the overall polarity of the context.
Context polarity = ∑ Polarityc
Where, c = number of concepts in the context and Polarityc
indicates the polarity score of each concept.</p>
      <p>Step 4: The context sentiment has been evaluated using
Context polarity score.
4</p>
    </sec>
    <sec id="sec-6">
      <title>Discussion and Evaluation</title>
      <p>The context related medical concepts and their semantic
features (extraction polarity, semantics and sense) are
required to identify the sentiment of the medical context
[Sarker et al., 2011]. In the process, the statistical and
linguistic features based medical sentiment lexicons were
facing difficulties due to the unstructured nature of the corpus.
So, the researchers tried to build an intelligent automated
sentiment extraction system in the Bio-NLP domain [Shukla
et al., 2015; Sohn et al., 2012]. The system helps to extract
the structured knowledge-based information with a proper
sentiment of the context. WordNet of Medical Event
(WME2.0) was introduced to identify the medical concept
and their sense-based features. The WME2.0 lexicon able to
extract the medical concepts and their POS, semantics,
gloss, affinity score, gravity score, polarity score and sense.
On the top of WME2.0 lexicon, the hybrid approach has
been applied to extract the context level sentiment for the
proposed model. The model is based on two phases namely
pre-processing and learning phase. The pre-processing
phase has considered the concept extraction (medical and
non-medical concept), concept cleansing (concept stemming
and stop-words removing) and concept formatting
&lt;Concept, POS, semantic, polarity score, sense&gt; steps. The
learning phase identified the sentiment using the linguistic and
machine learning approaches on the pre-processing step
driven data. The concept linguistic features and knowledge
based WME sentiment resource help to extract the overall
context sentiment and polarity score. The linguistic
approach provides a support to handle the negation and
identifies the correct sense of the context. The medical context
“No lung lesion found” has been evaluated as “positive”
sentiment after handling the negation. The system first
extracts the concepts and their sense as “no (-ve)”, “lung
(neutral)”, “lesion (-ve)” and “found (+ve)” using WME2.0
resource. The linguistic-based negation handling approach has
been applied on the extracted sense and identify the overall
context sense as “positive”. In the learning phase, the hybrid
approach has been introduced to extract and measure the
accuracy of the context sentiment. The linguistic approach
involves knowledge-based medical concept mapping with
WME2.0 lexicon. Further, the NaïveBayes and Sequential
minimal optimization (SMO) support vector based
supervised machine learning approaches have been employed for
evaluating the accuracy of the model. Figure 3 and Figure 4
describe the positive and negative contexts with respect to
the sentiment extraction process, respectively.
To develop and measure the accuracy of the context level
sentiment extraction system, the data has been collected
from the open source resource4. We have extracted 7042
number of medical contexts and applied through the
proposed sentiment extraction system. The context sentiment
extraction system has provided 3265 number of the positive
and 3777 number of the negative sentiments of the contexts.
To evaluate the extracted context sentiment, the linguistic
features (number of negation word, context polarity score
and sense) were fed to the NaïveBayes and support vector
based SMO supervised machine learning classifiers under
the WEKA5 tool. The extracted 7042 number of context
data has been represented as 4900 number of training and
the remaining 2142 number of test dataset. The system’s
accuracy was measured as F-Measure with four types of
models like, Use training set, Supplied test set,
Crossvalidation Folds 10 and Percentage split %66. Table 1
shows the F-Measures of these modes for the NaïveBayes
and support vector based SMO supervised classifiers. The
linguistic and machine learning based hybrid approach
provides the accuracy score nearly 81% for the medical context
sentiment extraction model.
4 http://www.medicinenet.com/
5 http://weka.wikispaces.com/</p>
    </sec>
    <sec id="sec-7">
      <title>Conclusion and Future scope</title>
      <p>Sentiment or opinion analysis is important to extract the
contextual information from the medical context under NLP
domain. The context sentiment helps to identify the
knowledge based information and proper utilization of the
context. The paper has reported a hybrid approach based
context sentiment extraction model with two phases. The
phases are preprocessing (important medical keywords
extraction) and learning (respective sentiment identification).
In the process, the linguistic and machine learning combined
hybrid approach has been applied on the top of WordNet of
Medical Event (WME2.0) lexicon to extract the medical
concepts in order to identify the sentiment of the medical
context. The medical concept polarity score and their related
sense helps to identify the medical context sentiment
[Cambria, 2013] and [Cambria et al., 2015]. WME2.0 lexicon
driven medical concepts affinity score and their semantic
features are crucial in building the proposed model. The
medical concept semantics, polarity score and affinity score
helps to identify the medical concept sentiment with polarity
score. The hybrid approach provides nearly 81% accuracy
for the proposed context sentiment extraction system.
Hence, the future research will focus to develop some
practical applications relating to the current work as medical
annotation and context summarization system. These
systems will provide the support to the expert and non-expert
groups in their respective applications.</p>
    </sec>
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