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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Bradley C.
Martin“Smartphone medication adherence apps:
Potential benefits to patients and providers” JAPha
Journal of the American Pharmacists Association
Volume 53</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>Albanian Mobile Assistant for Chronic Diseases</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Rezarta Kapaj</string-name>
          <email>rezarta.kapaj@fshn.edu.al</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Arbër Thaçi</string-name>
          <email>arberlthaci@gmail.com</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Alda Kika</string-name>
          <email>alda.kika@fshn.edu.al</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Department of Informatics, Faculty of Natural Sciences, University of Tirana</institution>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Software Developer, APPFORGOOD SRL</institution>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2014</year>
      </pub-date>
      <volume>53</volume>
      <issue>2</issue>
      <fpage>172</fpage>
      <lpage>181</lpage>
      <abstract>
        <p>The purpose of this paper is to present alMED, a mobile application designed to improve the self -management of chronic diseases by the patients themselves. Since the number of chronic disease patient is increasing every day worldwide, monitoring and management of chronic diseases is becoming a major concern even for the Albanian Healthcare System. The current state of alMED provides intelligent, user-friendly and secure application to keep track of the user medical records. It also works as a reminder for patients' medicine dosage and timings for multiple diseases. Patients are notified by the application each time they need to take a medicine, preventing them from forgetting to take them. In the future our goal is to make this application part of a larger system which includes the interaction between the patients, health care providers and pharmaceutical providers.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>smartphones to monitor chronical diseases and reduce
this way the number of hospitalized patients. Our goal
is to give Albanian smartphone users a solution to
improve their quality of life by managing their medical
records and medicine timetables. The main problem
concerning patient drugs treatment is that most of them
forget to take their medicines in the right time or
dosage, or even confuse treatment of one disease with
another. This causes medication adherence
[AAJKL15], which refers to the degree or extent to
which a patient takes the right medication at the right
time according to a doctor’s prescription.</p>
      <p>Many studies have reported that non-adherence may
critically affect the patient, thereby raising medical
costs [PL12]. Our system gives a solution for this
problem from the combination of sophisticated data
analytics and mobile technologies. [SN12]. Using the
mobile health application the patients will be able to
manage their health and the professionals will be able
to deliver the best care possible away from doctors and
hospitals, closer to where patients live work and travel
[ECL15]. alMED notifies the patients for the time and
dosage of the medication they have to take for every
disease. Except this it also provides a ‘Diary’ interface
to keep track of daily measurable health components.
applications of some kind by 2018. Further are listed
some of the best mobile application in Android and
IOS platforms [S15].</p>
      <p>This application is named alMED, where ‘al’ stands for
Albania and ‘MED’ stands for medication and
medicals.</p>
      <p>MyChart allow you to access your medical
records on your phone at any time. You can
quickly see which vaccinations you’ve had and
when at a glance, along with the last time you
visited the doctor and which prescriptions you’re
taking. You can even send a non-urgent message to
your clinic and receive a response within a couple
days, schedule visits from directly within the app,
and request prescription refills. Best of all, you can
see all your information online if you can’t access
it due to cellular outages.</p>
      <p>CareZone Managing medication can be a chore
(and confusing). Thankfully, CareZone lets you
curate a list of medications, dosages, and schedules
directly from your photo library. The application
also allows you to document and share symptoms
with your family or doctor, while giving you the
means to store vital insurance information and
schedule reminders for upcoming appointments.
The personalized health tips and ability to assign
to-do lists and store important documents for
future reference are only a plus.</p>
      <p>WebMD When people think of WebMD, it’s
probably just to make fun of how it’s often the first
place people go when they need to figure out what
illness or condition they have. The iOS application
offers the same thing, but alongside that, it also
allows people to set medication schedules, create a
process with which they can use to meet a personal
health goal, and check for local physicians and
pharmacies you may not be aware of. And if you
find yourself in need of a first aid advice or
instructions, the application has that too, and it
doesn’t require an internet connection.</p>
      <p>After reviewing the features that each one of the above
applications offers we will study the possibilities of
integrating and adopting the best of them in our system
considering all the challenges and conditions of the
Albanian healthcare system and users.</p>
    </sec>
    <sec id="sec-2">
      <title>3 Proposed System and Implementation</title>
      <p>Overall, this is a medical mobile application that assists
the users in planning their medical timetables. The
application is developed in Eclipse using Java for
Android as programming language, internal (SQLite)
[SQLITE16] and external libraries (Google Play
Services, MPAndroidCharts and A.C.R.A.).When the
application launches, the first interface is the ‘Diary’
interface which contains a list of daily measurable
components.
After daily check-up (this check-up is done by the user
itself or according to his doctor’s analysis) the user can
fill each of these components with the right data. Also,
the user can access his data for the previous or future
days from the calendar or from navigation buttons in
the action bar.</p>
      <p>The ‘Calendar’ interface of the application gives the
user a brief historical look to his own daily data, which
are saved in the local database. Clicking in a specific
date of the calendar sends the user to ‘Daily’ interface
on that date to display those data in detail.</p>
      <p>Another interface (which is also the core of this
application) is the ‘Therapy’ interface, which consists
in a list of all the therapies created by the user.
In the main menu there is also the profile icon, which
by clicking on it sends the user to the ‘Profile’
interface. In this interface the user can see his own
private data like his first name, last name and his photo.
In the profile it is also displays the types of diseases
from which the user suffers. The diseases are to be
chosen from a default list. The reason of choosing the
disease from a default list is that its name will be used
by BLE (Bluetooth Low Energy) to find other users
nearby which suffer from the same disease.</p>
      <sec id="sec-2-1">
        <title>Another feature of this</title>
        <p>implementation of Google Fit.
application
is
the
Google Fit does not offer just the service of the steps
management, but also the other services from the
fitness repository [FIT16]. These services are:
●
●</p>
      </sec>
      <sec id="sec-2-2">
        <title>Heartbeats</title>
      </sec>
      <sec id="sec-2-3">
        <title>Sleep</title>
        <p>Number of steps is calculated by Google based on
users’ physical activities, like walking or running.
GPS technology included in all Smartphone models
available in the market nowadays, offers the possibility
to obtain a good precision in performance analysis
through position and velocity of a motion body using
Satellite triangulation methods.
alMED takes advantage of this technology in order to
monitor data related to workout session of the patient:
- Distance/route taken in the workout session
- Instant and average speed of the session
alMED can make use of an array of sensors already
contained in modern, such as cameras, microphones,
GPS receivers, accelerometers, etc.</p>
        <p>In our application, beside the number of steps which
are shown in real time, the user can also access his
historical data. The historical data are displayed on two
forms:
● Numerical, which can be accessed from the
diary for the current date or the previous dates
● Graphical, which are overall data shown in
graphical view
Some of the main components of this large architecture
are:
To display the graphical view for the number of steps,
we have implemented an external library named
MPAndroidChart [GITHUB16]. Using its methods and
features we can provide to the user a very user friendly
graphical view. In our application we have chosen the
column chart. The graphical view displays the user’s
data since the installation until actual day. To make it
more interesting, the chart is also animated.</p>
        <p>The application is in Albanian because it is intended for
the Albanian market, and makes it user-friendly.
4 Future Challenges for an Integrated
Albanian Healthcare System
A future challenge in the application development
process is the inclusion in a cloud-based architecture.
Mobile health application combined with cloud based
technologies are becoming very handy to physicians
who will be able not only to access patients data, but
also to combine them with geolocation information
about bacteria, pattern of resistance, available drugs,
etc., all of which is stored in cloud.</p>
        <p>As mentioned in the beginning of this paper, our future
goal is to make this application part of a larger system
which includes several actors like patient, healthcare
providers and pharmaceutical providers. In this section
we will present some future ideas of the system
architecture and the roles of each actor in it.








1.
2.</p>
        <p>Patient: is a person with some kind of health
problem.</p>
        <p>Clinician: is a healthcare professional who is
treating or helping the Patient with the health
problem, i.e. a nurse, a General Practitioner, or a
specialized physician.</p>
        <p>HealthCare Provider (HCP): is the entity that is
utilizing a mobile health Service in the
monitoring, diagnosis and treatment of the
Patient.</p>
        <p>Mobile Health Service (mHS): is the service that
connects the Patient to the Clinician, and ensures
data measures, transport and protection.</p>
        <p>Mobile Health Service provider (mHSP): is the
entity providing the mHS through a mobile health
Platform (mHP).</p>
        <p>Mobile Health Platform (mHP): is the IT system
connected to the mobile network to provide all
necessary functionality.</p>
        <p>Mobile Health Device (mHD): is a device needed
to use the mHS and to connect to the mHP.</p>
        <p>Pharmacy: is the drugstore where the patient can
get the prescribed medicine.</p>
        <p>Another key-feature of this architecture, which also
represents an innovation in Albania, is the inclusion of
the pharmaceutical providers in this architecture. Here
is a simple use case for this actor as part of the system:
A Patient gets a medical prescription from the
Clinician
The mobile Health Service system platform (which
consists in centralized databases)
2.1 Returns a list of pharmacies matching the
request.
2.2 Makes this medical prescription available for
the pharmacies to review in case of the
patient request.</p>
        <p>A map is available for the patient to view the
nearest pharmacies.</p>
        <p>The patient can make electronic, online or cash
payment.
5. The patient goes to the nearest pharmacy to get the
prescription medicine.
**In some cases pharmacies may provide Home
Delivery.
Security requirements are also an important aspect
of mobile health system:
1. Device and data security (a) In memory (b)</p>
        <p>Processing (c) Transmission
2. Confidentiality and integrity of information
3. User authentication
4. System availability and access to resources
5. Non repudiation (useful in case of medical
prescription)
For widespread success, the development of m-health
must move away from small applications toward
largescale platform solutions [ATKEARNY13].
5</p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>Conclusions</title>
      <p>As in the developed countries, also in Albania the use
of health related mobile applications is expected to
increase in various healthcare settings. These
applications are thought to be a valuable tool for
patients, healthcare providers and other actors involved
in this schema, but not all use cases can be easily
integrated. Such systems and applications can be
particularly beneficial in developing countries like
Albania, where the health care system faces significant
challenges. For example, for various reasons, health
care workers struggle to provide satisfactory care for
their patients.</p>
      <p>Cultural factors such as language differences and
traditional healing practices may also present greater
obstacles to rural care than urban healthcare. Meshing
m-health interventions with these factors is critical for
promoting healthy behavior. Such reasons include the
cost of communication and transportation, lack of
scheduling, recording, and appropriate reminders, and
poor technology and infrastructure.</p>
      <p>Rural areas also usually have fewer health workers and
less infrastructure per person or square kilometer,
reducing the health system‘s ability to provide
highquality medical products and services.</p>
      <p>Mobile technology can aid in providing access to
information, helping to lower costs [KKV14],
facilitating remote care and increasing efficiencies by
connecting patients to their providers virtually
anywhere. Using a smartphone application is a novel
approach to improving adherence and patient behavior
[LSPPB13]; it is constantly accessible, involves and
educates the patient, and provides a repository for
patient­ and medication-specific information. Health
providers of the patients who take complex medication
regimens may value having the ability to input patients’
prescribed regimens and then “pushing” them directly
to patients’ smartphones. Interoperability with existing
prescription and medical records systems represents a
vital frontier for future application development. This
interoperability would shift the current orientation of
adherence applications to a more provider-focused
technology and thereby provide pharmacists a
potentially valuable tool to improve medication
adherence.
[ATKEARNY13] Mobile Health: Mirage or Growth
Opportunity
URL:https://www.atkearney.com/documents/10192/39
81820/Mobile-Health.pdf/422e1663-0c16-4c3d-afa4ad7be0293dc8
[FIT16] https://developers.google.com/fit/overview
[GITHUB16]
https://github.com/PhilJay/MPAndroidChart
[SQLITE16]
]http://www.tutorialspoint.com/android/android_sqlite_
database.htm
[ECL15] Elsevier Clinical Solutions “Mobile
Applications and the Future of Healthcare”
[SN12] Saltzestein.B dhe Nilsson.B (2012), ‘Bluetooth
Low Energy vs. Classic Bluetooth: Choose the Best
Wireless Technology For Your Application’, MED,
Medical Electronics Design,
[APG13] Arjen Hommersom, Peter J.F. Lucas,Marina
Velikova, Giso Dal “MoSHCA – My Mobile and Smart
Health Care Assistant” 2013 IEEE 15th International
Conference on e-Health Networking, Applications and
Services</p>
    </sec>
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</article>