=Paper= {{Paper |id=Vol-1747/D104_ICBO2016 |storemode=property |title=Updates to the AberOWL Ontology Repository |pdfUrl=https://ceur-ws.org/Vol-1747/D104_ICBO2016.pdf |volume=Vol-1747 |authors=Miguel Ángel Rodríguez-García,Luke Slater,Imane Boudellioua,Paul Schofield,Georgios Gkoutos,Robert Hoehndorf |dblpUrl=https://dblp.org/rec/conf/icbo/Rodriguez-Garcia16 }} ==Updates to the AberOWL Ontology Repository == https://ceur-ws.org/Vol-1747/D104_ICBO2016.pdf
                       Updates to the AberOWL ontology repository
           Miguel Ángel Rodrı́guez-Garcı́a 1∗, Luke T Slater 2 , Imene Boudellioua 1 , Paul N
                       Schofield 2 , Georgios V Gkoutos 3 , Robert Hoehndorf 1
       1
       Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal
                                                     23955-6900, KSA
    2
      College of Medical and Dental Sciences, Institute of Cancer and Genomic Sciences, Centre for Computational
                              Biology, University of Birmingham, B15 2TT, United Kingdom
                           3
                             University of Cambridge, Downing Street, CB2 3EG, England, UK




ABSTRACT                                                                and query these ontologies (i.e., AberOWL is used as a “Reasoning
   A large number of ontologies have been developed in the              as a Service” provider).
biological and biomedical domains, which are mostly expressed
in the Web Ontology Language (OWL). These ontologies form a             1.2   Manual curation of ontologies:
logical foundation for our knowledge in these domains, and they are     We have also manually curated the ontologies in AberOWL,
in widespread use to annotate biomedical and biological datasets.       assigning a set of ‘topics’ to them and allowing users to
The use of the semantics provided by ontologies requires the use        browse the ontologies through these means. The set of topics
of automated reasoning – inferring new knowledge by evaluating          were extracted from the ontology EMBRACE Data and Methods
the asserted axioms. AberOWL is an ontology repository which            (EDAM) [4] which is essentially a taxonomy of well established
utilises an OWL 2 EL reasoner to provide semantic access to             terms with synonyms and definitions related primarily within
classified ontologies. Since our original presentation of the AberOWL   bioinformatics. The annotations covered 177 different EDAM topics
framework, we have developed several additional tools and features      spanning all EDAM top-level topics such as: Medicine, Biology,
which enrich its ability to integrate and explore data, make use of     Data management, Laboratory techniques, Computer science,
the semantic and inferred content of ontologies. Here we present        Chemistry, Mathematics, Physics, Ontology and terminology
an overview of AberOWL and the enhancements and new features            and Literature and reference. For instance, the Amphibian
which have been developed since its conception. AberOWL is freely       Gross Anatomy Ontology (AAO) was classified with the topics
available at http://aber-owl.net.                                       eukaryotes, anatomy, and amphibians, and the Ascomycete
                                                                        Phenotype Ontology (APO) was annotated with fungi, phenomics
                                                                        and ascomycetes. The figure 1 shows a list of annotated ontologies
1      INTRODUCTION                                                     in AberOWL.
In recent years, several biological and biomedical ontology
repositories have been developed, such as BioPortal [5], Ontobee [7]    1.3   Ontology Browsing and Visualisation:
and the Ontology Lookup Service [2]. These provide web services         We have improved the tools available for browsing and exploring
and front-end interfaces for users to query and explore the content     ontologies. The class view in the ontology browser now shows the
of ontologies. AberOWL [3] is an ontology repository which utilises     definition of the class in Manchester OWL Syntax. Additionally,
automated reasoning to allow users to access the semantic content       the visualization module has been completely redesigned and we
of the ontologies. AberOWL provides both a web-based interface          plan to further integrate a new library called Dagre [6], which
for the exploration and browsing of ontologies and a set of REST        provides another way of representing ontologies by graphs instead
services which make the core functionality of AberOWL available         of trees. Thus, while the current visualization module represents
using the JSON standard [1].                                            cycles as a repeated subtree, the new module can easily include
                                                                        cycles without any repeated structure. Moreover, we plan to improve
1.1        Updates to AberOWL                                           the performance of this module by transforming the ontologies into
Ontology Acquisition, Curation and Statistics: When AberOWL             RDF graphs which will contain the inferred model of each ontology.
was originally presented in 2013, it contained 328 loadable             Thus, we will be able to significantly reduce the delay involved in
ontologies. Since then, our repository has grown to a total of 522      subclass computation.
ontologies. The amount of ontologies in AberOWL has increased
due to the growing number of ontologies in the biological and           REFERENCES
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∗ To     whom        correspondence     should     be      addressed:   [3]Robert Hoehndorf, Luke Slater, Paul N Schofield, and
miguel.rodriguezgarcia@kaust.edu.sa                                        Georgios V Gkoutos. Aber-owl: a framework for ontology-based


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                           Fig. 1. Screenshot of AberOWL that shows the list of annotated ontologies by using the EDAM topics.


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