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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Dealing with elements of medical encounters: an approach based on ontological realism</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Fernanda Farinelli</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
          <xref ref-type="aff" rid="aff3">3</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Mauricio Barcellos Almeida</string-name>
          <xref ref-type="aff" rid="aff2">2</xref>
          <xref ref-type="aff" rid="aff3">3</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Peter Elkin</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Barry Smith</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Department of Biomedical Informatics</institution>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Department of Philosophy, University at Buffalo</institution>
          ,
          <addr-line>Buffalo NY</addr-line>
          ,
          <country country="US">USA</country>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>National Center for Ontological Research, University at Buffalo</institution>
          ,
          <addr-line>Buffalo NY</addr-line>
          ,
          <country country="US">USA</country>
        </aff>
        <aff id="aff3">
          <label>3</label>
          <institution>School of Information Science, Federal University at Minas Gerais</institution>
          ,
          <addr-line>Belo Horizonte, MG</addr-line>
          ,
          <country country="BR">Brazil</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>- Electronic health records (EHRs) serve as repositories of documented data collected in a health care encounter. An EHR records information about who receives, who provides the health care and about the place where the encounter happens. We also observe additional elements relating to social relations in which the healthcare consumer is involved. To provide a consensus representation of common data and to enhance interoperability between different EHR repositories we have created a solution grounded in formal ontology. Here, we present how an ontology for the obstetric and neonatal domain deals with these general elements documented in health care encounters. Our goal is to promote the interoperability of information among EHRs created in different specialties. To develop our ontology, we used two main approaches: one based on ontological realism, the other based on the principles of the OBO Foundry, including reuse of reference ontologies.</p>
      </abstract>
      <kwd-group>
        <kwd />
        <kwd>Biomedical Ontology</kwd>
        <kwd>Obstetric and Neonatal Ontology</kwd>
        <kwd>electronic health records</kwd>
        <kwd>BFO</kwd>
        <kwd>OBO Foundry</kwd>
        <kwd>social entities</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>INTRODUCTION</p>
      <p>
        The motivation here grows out of the workings of the Stork
Network Program, a Brazilian Healthcare Program that aims to
provide comprehensive care of both woman and child during the
course of pregnancy and in the postpartum stage. The
organization of healthcare in Brazil involves health facilities at
different government levels each of which has certain autonomy.
These government levels are even free to adopt their own
electronic health record (EHR) information systems, which
creates challenges to data interoperability. To address some of
these challenges we are developing the Obstetric and Neonatal
Ontology (OntONeo) [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ], which aims to represent the diversity
of data registered in EHRs involved in pregnancy care.
OntONeo is an initiative to overcome failures of semantic
interoperability among EHR information systems that were built
using different standards and terminologies.
      </p>
      <p>The scope of OntONeo was defined from a set of Brazilian
and international EHR standards, for instance: the Woman’s
Health Record and Antepartum Record and Postpartum Form
provided by the American College of Obstetricians and
Gynecologists (ACOG); the Children’s Electronic Health
Record Format provided by the Agency for Healthcare Research
and Quality (AHRQ). We also conducted interviews with
Brazilian and American obstetricians to identify the workflow
of the women's health clinic and the information needs of this
medical practice. In the future, we will conduct interviews also
with pediatricians to identify their needs.</p>
      <p>The course of pregnancy, childbirth and child development
involves a series of stages referred to as the prenatal, intrapartum
and postnatal periods of care [2; 7]. Clinical care in each of these
stages calls upon different medical specialties. Information
pertaining to all stages of care is recorded in specific EHRs
according to their specialty of origin.</p>
      <p>EHRs across different medical specialties need information
about elements observed in medical encounters. Each such
encounter necessarily involves three elements: first, the location
where clinical activity is performed, named health care facility;
second, who performs or serves as the provider of health care,
named the human health care provider; and third, who
participates in an event as recipient of health care (consumers),
named the human health care consumer.</p>
      <p>
        In addition, during the health care encounter a provider
collects demographic data from a consumer. The demographic
data section of an EHR is more than just data to allow the
identification and categorization of the consumer [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. It includes
also information needed to locate the consumer and data about
people related to the consumer: the consumer’s emergency
contact, information about the spouse or partner of the
consumer, and finally, if the consumer is a minor, information
about the legally responsible person. All of these persons are
elements that are documented in medical encounters and
included in a corresponding demographic sub-section of the
EHR. They are connected to a consumer by social relations, as
a marital status defined by Ontology of Medically Related
Social Entities (OMRSE) [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ].
      </p>
      <p>
        Our representation of the demographic data section of the
EHR and the elements of the medical encounter are quite
generic. We follow the practice of the Ontology for General
Medical Science (OGMS) which deal with general terms of
medicine used across medical disciplines [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ]. Thus they will
meet not only the needs of interoperability of the Stork Network
Program, but also corresponding needs of EHRs pertaining to
any medical specialty.
      </p>
      <p>This paper describes the OntONeo approach to deal with the
elements present in medical appointments: the consumer and the
provider in a medical encounter, the place of the health care
facility, and the social relations of the consumer that are
important to document. We are extending OGMS and OMRSE
to the specific case of pregnancy.
(OGMS) and Ontology of Medically Related Social Entities
(OMRSE).</p>
    </sec>
    <sec id="sec-2">
      <title>METHODOLOGY</title>
      <p>
        To build OntONeo we adopt the principals of ontological
realism to foster semantic coherence, both for humans and
computers [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ]. On the view of ontological realism a useful
domain ontology should be built not to represent existing data
or models of a domain, but rather to represent the relevant
established science. The set of principles established to foster
achievement of this goal are summarized in [1; 8].
      </p>
      <p>
        The top-level ontology used as starting point for OntONeo
is the Basic Formal Ontology 2.0 [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. To maximize the
interoperability among biomedical ontologies, and following the
OBO Foundry principles [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ], we reuse previous ontologies
developed as: Ontology of Document Acts (d-acts), Phenotype
Ontology (PATO), and Ontology for Biomedical Investigations
(OBI), in addition to Ontology for General Medical Science
OntONeo is divided into modules designed to meet specific
needs. In this work, we present the part of the OntONeo-Social
that covers the domain of social entities involved in obstetric and
neonatal care, such as family relations and demographic
information.
      </p>
    </sec>
    <sec id="sec-3">
      <title>III. ELEMENTS OF A MEDICAL APPOINTMENT</title>
      <p>Fig. 1 and 2 show a sketch of the elements documented in a
health care encounter. Terms in black represent entities reused
from BFO, terms in gray are taken over from other ontologies;
and terms in white are new entities of OntONeo. The term health
care encounter is defined by OGMS ontology as a process in
which at least one human being participates. Then we have in
OMRSE ontology the term Homo sapiens that was reused from
NCBI organismal.
IV. CONCLUSION AND REMARKS</p>
      <p>This paper described how OntONeo deals with the elements
involved in a health care encounter. These elements defined by
OntONeo has the potential to contribute to interoperability of
information among EHR from different specialties. In addition,
these definitions facilitate the understanding of how such
information can be organized in EHRs for purposes of
healthcare.</p>
      <p>OntONeo is an on-going project in the early stages of
development, and the current version is available on the web at
http://ontoneo.wordpress.com. Its worth to mention that this
work is justified above all by the lack of formal representations
in the obstetric and neonatal domains.</p>
      <p>ACKNOWLEDGMENT</p>
      <p>We thank CAPES and CNPq for financial support to the
primary author. This work is also supported in part by the NIH
NCATS under CTSA award Number UL1TR001412.</p>
    </sec>
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