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    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Comparison​ ​of​ ​machine​ ​learning​ ​methods​ ​for​ ​predicting the​ ​recovery​ ​time​ ​of​ ​professional​ ​football​ ​players​ ​after​ ​an undiagnosed​ ​injury</article-title>
      </title-group>
      <abstract>
        <p>​. ​Injuries are a common problem in professional football. A challenge that the medical team faces is to successfully predict the recovery time of an injured player. Current medical standards can only give vague predictions as to when a player will return to play. Obviously, making an accurate prediction as soon as possible would be helpful to the coach. This research tries to answer the question of whether it is possible to predict when a player will return to play, based on information at the moment of injury, while also comparing three machine learning methods for this task: support vector machines, Gaussian processes and neural networks. The tests were conducted on data from the professional football club of Tottenham Hotspur. The results demonstrate that this task can be completed with a reasonable amount of accuracy, without any method performing significantly better than the rest. Future directions​ ​and​ ​possible​ ​improvements​ ​are​ ​discussed.</p>
      </abstract>
      <kwd-group>
        <kwd>​ ​injury​ ​prediction</kwd>
        <kwd>​ ​football</kwd>
        <kwd>​ ​support​ ​vector​ ​machine</kwd>
        <kwd>​ ​neural​ ​network</kwd>
        <kwd>Gaussian​ ​process</kwd>
        <kwd>​ ​comparison</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>Injuries are a common problem in every sport, including football. Professional
football players get injured on average once per year [1] with 10-35 injuries occurring
per 1000 game hours [2]. Injuries have been described as the main factor that prevents
professional players from not being able to participate in training and playing
activities​ ​[3].</p>
      <p>
        The factors that cause injuries can vary. A significant percentage of injuries
(9%-34%) happening due to overuse [4-5]. Most of the injuries are described as
traumatic, with 29% of them being due to foul play [
        <xref ref-type="bibr" rid="ref1">6</xref>
        ]. The majority of injuries
happen​ ​in​ ​play,​ ​and​ ​the​ ​most​ ​severe​ ​cases​ ​can​ ​be​ ​attributed​ ​to​ ​body​ ​contact​ ​[
        <xref ref-type="bibr" rid="ref23">7</xref>
        ].
      </p>
      <p>As soon as an injury happens it is important to make an estimate of how long the
player will need to recover from the injury and get back to play. This information can
help the manager make appropriate changes in the squad or the tactical planning of
the team. It can also help the director of the club, since new players might need to get
signed in order to cover for players who are going to stay out of play for a long time.
Additionally, managing the player’s expectations with respect to his injury is
important, so that the player can prepare himself mentally and psychologically.
Finally, it would help the medical team by providing additional certainty in the
predictions​ ​of​ ​the​ ​experts.</p>
      <p>Currently, there is no standard method to estimate the time a player will miss from
play. The time is estimated based on the experience of the physician and by
recommendations by various groups and studies. The suggestions can vary quite
significantly with each other, and they can also have significant variance. For
example, suggestions for return to play following anterior cruciate ligament
reconstruction can range from 16 to 24 weeks [8]. Similar recommendations exist for
hamstring​ ​injuries​ ​[9]​ ​and​ ​concussions​ ​[10-13].</p>
      <p>Machine learning has been used in sports for various purposes (e.g. cycling [14]
and swimming [15] ) including football [16-17]. The complicated and multi-factorial
nature​ ​of​ ​many​ ​sports​ ​makes​ ​machine​ ​learning​ ​a​ ​natural​ ​choice​ ​for​ ​predictive​ ​tasks.</p>
      <p>The purpose of this study is to compare different machine learning methods on
predicting the recovery time of professional football athletes. The goal is to make the
prediction based on information available at the time of injury, before an official
diagnosis has been conducted. There are two main reasons for which the final
diagnosis was left out. First, diagnoses, in some cases, can take some time, while
ideally a coach would like know as soon as possible how long a player will stay out of
play.</p>
      <p>Secondly, there are many different diagnoses and different levels of abstraction that
can be used. For example, in this study’s dataset there were some knee injuries that
were described as “knee pain, unspecified”, “patellofemoral pain” and “Left knee
medial meniscus”. These diagnoses could be elaborated even further, or they could be
abstracted, by classifying them all as “knee injuries”. This is a medical problem that
can influence the performance of any machine learning or statistical model that will
use​ ​this​ ​information.</p>
      <p>However, it is not entirely clear what degree of elaboration would actually help in
the prediction of the response variable. For that reason it is important to know what
degree of accuracy can be achieved in the prediction of the response variable before
including the diagnosis, so that future research could actually tackle the problem of
trying​ ​to​ ​identify​ ​the​ ​correct​ ​level​ ​of​ ​abstraction​ ​needed​ ​for​ ​this​ ​task.</p>
      <p>The methods that were chosen for this research were Gaussian processes, support
vector machines and neural networks. The reason behind these choices is that all these
methods are popular for regression tasks. While there are many other choices for
solving regression problems in machine learning, these three methods have been
proved and tested in a variety of applications, so they provide sensible choices for
approaching​ ​this​ ​task.</p>
      <p>The primary goal of this study was to test the degree to which this task is possible
in general by reaching a level of error in the predictions that can have practical
applicability, at least in some cases. Once this was established, the next goal was to
see whether one of these methods is more suited for this task compared to others. The
study itself is part of a greater research project that has as a final goal a fully-working
predictive system that can aid football teams. Therefore, future plans, directions and
suggestions​ ​for​ ​research​ ​are​ ​discussed,​ ​as​ ​well.
2
2.1</p>
    </sec>
    <sec id="sec-2">
      <title>Methods</title>
    </sec>
    <sec id="sec-3">
      <title>The​ ​dataset</title>
      <p>The dataset consists of a list of injuries at Tottenham Hotspur Football Club. For
every injury, a list of variables was collected. These are presented in table 1. Note that
the variable “injury” included in the dataset is not a final diagnosis, but a first general
estimate​ ​such​ ​as​ ​“muscle​ ​strain”​ ​or​ ​“bone​ ​injury”.</p>
      <p>All variables, with the exception of “Age” and “Days unavailable” were categorical
variables and they were converted to dummy variables. This gave rise to a dataset that
contains​ ​78​ ​variables​ ​(including​ ​the​ ​response​ ​variable).</p>
      <p>A histogram of the dataset is shown in figure 1. It is evident that most of the
injuries are less than 25 days and the histogram is skewed. The total number of cases
is​ ​154.</p>
      <p>Three different methods were used and evaluated: neural networks, support vector
machines and Gaussian processes. Each method was executed with many different
parameter sets. In order to find the best parameters, grid search was used. Due to the
number of tests (more than 50 tests for each method) conducted it is not practical to
provide tables and graphs for each parameter set and result. Therefore, tables 2-6
below​ ​show​ ​the​ ​parameters​ ​that​ ​each​ ​method​ ​used​ ​and​ ​their​ ​value​ ​ranges.</p>
      <p>The​ ​neural​ ​network​ ​was​ ​trained​ ​using​ ​backpropagation​ ​with​ ​momentum.
Min
Max
Min
Max
Min
Max</p>
      <p>C
0
200
Min</p>
      <p>Max</p>
      <sec id="sec-3-1">
        <title>Epochs 1500 3000</title>
      </sec>
      <sec id="sec-3-2">
        <title>Table​ ​2.​ ​Neural​ ​network​ ​parameters</title>
        <p>Learning Momentum
Rate
0.2 0.2
0.5 0.4</p>
        <p>For this particular task, it was observed that it was difficult to evaluate the success
of the algorithms by using the standard mean squared error alone. The interpretability
of the results is crucial, and the mean squared error is difficult to be communicated to
a medical professional. For that reason, the absolute error was used in addition to the
mean squared error when reporting results, even though the mean squared error was
the optimization objective in each trial. All methods were evaluated using 10-fold
cross​ ​validation​ ​and​ ​all​ ​tests​ ​were​ ​executed​ ​using​ ​RapidMiner​ ​version​ ​5.3.</p>
        <p>Another issue with the evaluation of the results is the desired degree of accuracy
that is required for a method in this task to be considered successful from the
perspective of practical applicability. Football teams play a certain amount of games
within a season. Usually this is 4 league games per month, and maybe some more cup
games and games in European competitions. If a player is injured in a game, it might
not matter so much whether he will be back in play in 3 or 5 days, as long as the
coach​ ​knows​ ​that​ ​in​ ​7​ ​days,​ ​when​ ​the​ ​next​ ​game​ ​starts,​ ​he​ ​will​ ​be​ ​ready​ ​to​ ​play.</p>
        <p>Furthermore, the dataset contains many cases where the player stayed out of play
for one day or no days at all. Many of these cases do not require the execution of a
predictive algorithm, because the medical professionals of the team can very quickly
classify the injury as transient. Predictions are more helpful for injuries that have
longer lasting effects, for example, more than a couple of weeks. This means, that the
margin of error can be higher. If the medical staff’s opinion is that a player will miss 5
to 10 weeks, then a prediction that manages to narrow down this margin to, for
example, 6 to 7 weeks, can help the coach make better decisions and plan for the
future.
3</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>Results</title>
      <p>The best results achieved for each method are in table 7. The errors are presented
for both the test data and the whole dataset. The test errors are accompanied by their
corresponding standard deviations, as they have been calculated from the 10-fold
cross-validation. Standard deviations do not apply to the total errors, since they are
computed​ ​for​ ​the​ ​whole​ ​dataset.</p>
    </sec>
    <sec id="sec-5">
      <title>Discussion</title>
      <p>It is evident that this task can be predicted with some degree of accuracy. The test
accuracies are similar, and their variances are big, so no single method seems to
perform significantly better to others. However, the important point is that the task
can be completed with a fair degree of accuracy. It is possible to make an estimate of
when a player will return to play based on information at the moment of injury, before
an​ ​official​ ​diagnosis​ ​is​ ​conducted.</p>
      <p>The absolute error that the algorithms achieve in the test accuracy is about in the
range (17, 21). This makes their application, as they are, more suitable for
mid-severity to severe injuries where the player is likely to stay out of play for a
month​ ​or​ ​more.</p>
      <p>The results are even more important if it is considered that the size of the dataset
should be considered small for this task and it concerns only a single football club.
There are many types of injuries in football that can occur under different
circumstances. Future research should use datasets from other football clubs in order
to verify and expand the current results. Ideally, datasets from football clubs from
different countries should be obtained, since the style of play in each country, along
with​ ​other​ ​factors​ ​(e.g.​ ​a​ ​country’s​ ​climate),​ ​could​ ​influence​ ​the​ ​response​ ​variables.</p>
      <p>Obviously, the end goal is the practical applicability of the results. An interesting
feature of this task is that the models could be included in a diagnostic protocol. After
each injury, the medical staff will conduct detailed medical tests in order to diagnose
the injury. Models like the ones described in this paper could accompany a diagnosis,
providing​ ​some​ ​additional​ ​support​ ​for​ ​the​ ​experts’​ ​estimates.</p>
      <p>Furthermore, additional information that could be available at the moment of injury
includes anthropometric and medical information such as the height, weight or
medical blood tests of players. This information could improve the accuracy of the
model, while also staying true to its original goal of making predictions right after an
injury​ ​has​ ​occurred.</p>
      <p>Finally, future research could also solve the problem of how additional official
diagnostic information could be used alongside this model in order to make more
accurate​ ​predictions.
5</p>
    </sec>
    <sec id="sec-6">
      <title>Conclusion</title>
      <p>This research dealt with the question of whether it is possible to predict the
recovery time after an injury in professional football without an official diagnosis,
while it also testing 3 methods against each other for this task. The results
demonstrate that it is possible to reach some degree of accuracy in this task, but the
size of the dataset, and maybe the variables themselves, limit the accuracy that can be
reached. No single method was deemed to be significantly better than any of the other
methods​ ​that​ ​were​ ​used.</p>
      <p>However, this work paves the way for future research that can include bigger and
more complicated datasets and can also be extended by protocols that can combine
experts’ opinions. Future research will built on top of the current results in order to
provide​ ​a​ ​functional​ ​system​ ​for​ ​assessing​ ​injuries​ ​in​ ​professional​ ​football.
6</p>
    </sec>
    <sec id="sec-7">
      <title>Acknowledgments</title>
      <p>The author of this research would like to thank Wayne Diesel of Tottenham
Hotspur​ ​Football​ ​Club​ ​for​ ​kindly​ ​sharing​ ​the​ ​data​ ​for​ ​this​ ​research.
18.
19.</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          6.
          <string-name>
            <given-names>A.</given-names>
            <surname>Junge</surname>
          </string-name>
          and
          <string-name>
            <given-names>J.</given-names>
            <surname>Dvorak</surname>
          </string-name>
          ,
          <article-title>"Soccer injuries: a review on incidence and</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          <string-name>
            <surname>prevention</surname>
          </string-name>
          ,"​ ​Sports​ ​ Medicine,​ ​ vol.​ ​
          <volume>34</volume>
          ,​ ​no.​ ​
          <volume>13</volume>
          ,​ ​pp.​ ​
          <fpage>929</fpage>
          -
          <lpage>938</lpage>
          ,​ ​
          <year>2004</year>
          .
          <string-name>
            <given-names>J.</given-names>
            <surname>Dvorak</surname>
          </string-name>
          and
          <string-name>
            <given-names>A.</given-names>
            <surname>Junge</surname>
          </string-name>
          ,
          <article-title>"Football injuries and physical symptoms: a review of</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref3">
        <mixed-citation>
          <article-title>the​ ​literature,"​ ​The​</article-title>
          ​ American​ ​ Journal​ ​ of​ ​ Sports​ ​ and​ ​ Medicine,​ ​ vol.​ ​
          <volume>28</volume>
          ,​ ​no.
          <issue>​</issue>
          ​5,​ ​
          <year>2000</year>
          .
          <string-name>
            <given-names>L.</given-names>
            <surname>Parry</surname>
          </string-name>
          and
          <string-name>
            <given-names>B.</given-names>
            <surname>Drust</surname>
          </string-name>
          ,
          <article-title>"Is injury the major cause of elite soccer players being</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref4">
        <mixed-citation>
          <string-name>
            <surname>Sport</surname>
          </string-name>
          ,​ ​ vol.​ ​7,​ ​no.
          <issue>​</issue>
          ​2,​ ​pp.​ ​
          <fpage>58</fpage>
          -
          <lpage>64</lpage>
          ,​ ​
          <year>2006</year>
          . A.
          <string-name>
            <surname>Arnason</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          <string-name>
            <surname>Gudmundsson</surname>
            ,
            <given-names>H. A.</given-names>
          </string-name>
          <string-name>
            <surname>Dahl</surname>
            and
            <given-names>E. Jóhannsson,</given-names>
          </string-name>
          "Soccer injuries
        </mixed-citation>
      </ref>
      <ref id="ref5">
        <mixed-citation>
          <source>in Iceland," ​Scandinavian Journal of Sports &amp; Medicine in Sports, ​</source>
          vol.
          <volume>6</volume>
          , no.
          <issue>1</issue>
          ,
        </mixed-citation>
      </ref>
      <ref id="ref6">
        <mixed-citation>
          pp.​ ​
          <fpage>40</fpage>
          -
          <lpage>45</lpage>
          ,​ ​
          <year>1996</year>
          .
          <string-name>
            <given-names>A. B.</given-names>
            <surname>Nielsen</surname>
          </string-name>
          and
          <string-name>
            <given-names>J.</given-names>
            <surname>Yde</surname>
          </string-name>
          ,
          <article-title>"Epidemiology and traumatology of injuries in</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref7">
        <mixed-citation>
          <string-name>
            <surname>soccer</surname>
          </string-name>
          ," ​The American Journal of Sports Medicine, ​ vol.
          <volume>17</volume>
          , no.
          <issue>6</issue>
          , pp.
          <fpage>803</fpage>
          -
          <lpage>807</lpage>
          ,
        </mixed-citation>
      </ref>
      <ref id="ref8">
        <mixed-citation>
          <string-name>
            <surname>1989. R. D. Hawkins</surname>
            and
            <given-names>C. W.</given-names>
          </string-name>
          <string-name>
            <surname>Fuller</surname>
          </string-name>
          ,
          <article-title>"Risk assessment in professional football: an</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref9">
        <mixed-citation>
          <article-title>examination of accidents and incidents in the 1994 World Cup finals,"</article-title>
          ​British
        </mixed-citation>
      </ref>
      <ref id="ref10">
        <mixed-citation>
          <string-name>
            <surname>Journal</surname>
          </string-name>
          ​ ​ of​ ​ Sports​ ​ Medicine,​ ​ vol.​ ​
          <volume>30</volume>
          ,​ ​no.
          <issue>​</issue>
          ​2,​ ​pp.​ ​
          <fpage>165</fpage>
          -
          <lpage>170</lpage>
          ,​ ​
          <year>1996</year>
          . L.
          <string-name>
            <surname>Peterson</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          <string-name>
            <surname>Junge</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          <string-name>
            <surname>Chomiak</surname>
          </string-name>
          ,
          <string-name>
            <surname>T.</surname>
            Graf-Baumann and
            <given-names>J.</given-names>
          </string-name>
          <string-name>
            <surname>Dvorak</surname>
          </string-name>
          ,
          <article-title>"Incidence</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref11">
        <mixed-citation>
          The​ ​ American​ ​ Journal​ ​ of​ ​ Sports​ ​ Medicine,​ ​ vol.​ ​
          <volume>28</volume>
          ,​ ​no.
          <issue>​</issue>
          ​5,​ ​
          <year>2000</year>
          .
          <string-name>
            <given-names>M.</given-names>
            <surname>Bizzini</surname>
          </string-name>
          ,
          <string-name>
            <given-names>D.</given-names>
            <surname>Hancock</surname>
          </string-name>
          and
          <string-name>
            <given-names>F.</given-names>
            <surname>Impellizzeri</surname>
          </string-name>
          ,
          <article-title>"Suggestions from the field for</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref12">
        <mixed-citation>
          <string-name>
            <surname>soccer</surname>
          </string-name>
          ," ​
          <source>The Journal of Orthepaedic and Sports</source>
          Physical Therapy, ​ vol.
          <volume>42</volume>
          , no.
          <issue>4</issue>
          ,
        </mixed-citation>
      </ref>
      <ref id="ref13">
        <mixed-citation>
          2012.
          <string-name>
            <given-names>J.</given-names>
            <surname>Mendiguchia</surname>
          </string-name>
          and
          <string-name>
            <given-names>M.</given-names>
            <surname>Brughelli</surname>
          </string-name>
          ,
          <article-title>"A return-to-sport algorithm for acute</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref14">
        <mixed-citation>
          <article-title>hamstring​ ​injuries,"​ ​Physical​ ​ Therapy​</article-title>
          ​ in​ ​ Sport,​ ​ vol.​ ​
          <volume>12</volume>
          ,​ ​no.
          <issue>​</issue>
          ​1,​ ​
          <year>2011</year>
          . R. C.
          <article-title>Cantu, "Guidelines for return to contact sports after a cerebral</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref15">
        <mixed-citation>
          <string-name>
            <surname>concussion</surname>
          </string-name>
          ,"​ ​Physician​ ​ and​ ​ Sports​ ​ Medicine,​ ​ vol.​ ​
          <volume>14</volume>
          ,​ ​no.​ ​
          <volume>10</volume>
          ,​ ​pp.​ ​
          <fpage>75</fpage>
          -
          <lpage>83</lpage>
          ,​ ​
          <year>1986</year>
          . G. Dicker,
          <article-title>"A sports doctor's dilemma in concussion,"</article-title>
          ​Sports Medicine
        </mixed-citation>
      </ref>
      <ref id="ref16">
        <mixed-citation>
          <string-name>
            <surname>Training</surname>
          </string-name>
          ​ ​ and​ ​ Rehabilitation,​ ​ vol.​ ​2,​ ​pp.​ ​
          <fpage>203</fpage>
          -
          <lpage>209</lpage>
          ,​ ​
          <year>1991</year>
          .
          <string-name>
            <given-names>M.</given-names>
            <surname>Lovell</surname>
          </string-name>
          , M. Collins and
          <string-name>
            <given-names>J.</given-names>
            <surname>Bradley</surname>
          </string-name>
          ,
          <article-title>"Return to play following sports-related</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref17">
        <mixed-citation>
          <string-name>
            <surname>concussion</surname>
          </string-name>
          ,"​ ​Clinics​ ​ in​ ​ Sports​ ​ Medicine,​ ​ vol.​ ​
          <volume>23</volume>
          ,​ ​pp.​ ​
          <fpage>421</fpage>
          -
          <lpage>441</lpage>
          ,​ ​
          <year>2004</year>
          . M. W. Collins,
          <string-name>
            <given-names>M. R.</given-names>
            <surname>Lovell</surname>
          </string-name>
          and
          <string-name>
            <surname>D. B. McKeag</surname>
          </string-name>
          ,
          <article-title>"Current issues in managing</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref18">
        <mixed-citation>
          <article-title>sports concussion," ​The Journal of the American Medical Association</article-title>
          , ​ vol.
          <volume>282</volume>
          ,
        </mixed-citation>
      </ref>
      <ref id="ref19">
        <mixed-citation>
          pp.​ ​
          <volume>2283</volume>
          ​ ​-​ ​
          <fpage>2285</fpage>
          ,​ ​
          <year>1999</year>
          .
          <string-name>
            <given-names>B.</given-names>
            <surname>Ofoghi</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            <surname>Zeleznikow</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            <surname>MacMahon</surname>
          </string-name>
          and
          <string-name>
            <given-names>D.</given-names>
            <surname>Dwyer</surname>
          </string-name>
          , "Supporting athlete
        </mixed-citation>
      </ref>
      <ref id="ref20">
        <mixed-citation>
          <article-title>learning​ ​approach,"</article-title>
          ​ ​Information​ ​ Sciences,​ ​ vol.​ ​
          <volume>233</volume>
          ,​ ​pp.​ ​
          <fpage>200</fpage>
          -
          <lpage>213</lpage>
          ,​ ​
          <year>2013</year>
          .
          <string-name>
            <given-names>E.</given-names>
            <surname>Meżyk</surname>
          </string-name>
          and
          <string-name>
            <surname>O. Unold,</surname>
          </string-name>
          <article-title>"Machine learning approach to model sport training,"</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref21">
        <mixed-citation>
          <string-name>
            <surname>Computers</surname>
          </string-name>
          ​ ​ in​ ​ Human​ ​ Behavior,​ ​ vol.​ ​
          <volume>27</volume>
          ,​ ​no.
          <issue>​</issue>
          ​5,​ ​p.​ ​
          <fpage>1499</fpage>
          -
          <lpage>1506</lpage>
          ,​ ​
          <year>2011</year>
          . A.
          <string-name>
            <surname>Joseph</surname>
            ,
            <given-names>N. E.</given-names>
          </string-name>
          <string-name>
            <surname>Fenton</surname>
            and
            <given-names>M.</given-names>
          </string-name>
          <string-name>
            <surname>Neil</surname>
          </string-name>
          ,
          <article-title>"Predicting football results using Bayesian</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref22">
        <mixed-citation>
          <article-title>nets and other machine learning techniques," ​Knowledge-Based Systems</article-title>
          , ​ vol.
          <volume>19</volume>
          ,
        </mixed-citation>
      </ref>
      <ref id="ref23">
        <mixed-citation>
          no.
          <issue>​</issue>
          ​7,​ ​pp.​ ​
          <fpage>544</fpage>
          -
          <lpage>553</lpage>
          . B.
          <string-name>
            <surname>Min</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          <string-name>
            <surname>Kim</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          <string-name>
            <surname>Choe</surname>
            ,
            <given-names>H.</given-names>
          </string-name>
          <string-name>
            <surname>Eom</surname>
            and
            <given-names>B. R. I. McKay</given-names>
          </string-name>
          ,
          <article-title>"</article-title>
          A compound
        </mixed-citation>
      </ref>
      <ref id="ref24">
        <mixed-citation>
          <string-name>
            <surname>Systems</surname>
          </string-name>
          ,​ ​ vol.​ ​
          <volume>21</volume>
          ,​ ​no.
          <issue>​</issue>
          ​7,​ ​
          <year>2008</year>
          . S.​ ​Marsland,​ ​Machine​ ​learning:​ ​an​ ​algorithmic​ ​perspective,​ ​CRC​ ​Press,​ ​
          <year>2009</year>
          .
          <string-name>
            <given-names>A.</given-names>
            <surname>Junge</surname>
          </string-name>
          and
          <string-name>
            <given-names>J.</given-names>
            <surname>Dvorak</surname>
          </string-name>
          ,
          <article-title>"Influece of definition and data collection on the</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref25">
        <mixed-citation>
          vol.​ ​
          <volume>28</volume>
          ,​ ​no.
          <issue>​</issue>
          ​5,​ ​
          <year>2000</year>
          .
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>