=Paper= {{Paper |id=Vol-2022/paper25 |storemode=property |title= The EU's Human Brain Project (HBP) Flagship - Accelerating Brain Science Discovery and Collaboration |pdfUrl=https://ceur-ws.org/Vol-2022/paper25.pdf |volume=Vol-2022 |authors=Katrin Amunts |dblpUrl=https://dblp.org/rec/conf/rcdl/Amunts17 }} == The EU's Human Brain Project (HBP) Flagship - Accelerating Brain Science Discovery and Collaboration == https://ceur-ws.org/Vol-2022/paper25.pdf
        The EU's Human Brain Project (HBP) Flagship –
      Accelerating brain science discovery and collaboration
                                                (Extended Abstract)
                                                  © Katrin Amunts,
                                           Jülich, Düsseldorf, Germany
          Abstract. The human brain has a multi-level organisation and high complexity. New approaches are
    necessary to decode the brain with its 86 billion nerve cells, which form extensive networks. Ultra-high
    resolution models of the brain pose massive challenges in terms of data processing, visualisation and analysis.
    The Human Brain Project creates a cutting-edge European infrastructure to enable cloud-based collaboration
    among researchers from different disciplines around the world. The infrastructure includes development
    platforms with databases, workflow systems, petabyte storage. New technologies, including neuromorphic
    computing and robotics are being developed. Neuroscientists and ICT-specialists collaborate in a co-design
    process, based on neuroscientific use cases, to develop such infrastructure, thus opening new perspective to
    decode the human brain.
          Keywords: data analytics, data management, future computing, neuroinformatics, neuroscience.


1 Introduction                                                        The HBP infrastructure will enable cloud-based
                                                                  collaboration among researchers coming from
    The human brain has a highly complex, multi-level             different disciplines around the world. To achieve this,
organisation. New approaches are necessary to decode              research platforms include databases, workflow
the brain with its 86 billion nerve cells, which form             systems, petabyte storage, and supercomputers, to
complex networks – a challenge that is addressed by               address the requirements of the different users.
the Human Brain Project (1). E.g., 3D Polarized Light
Imaging (2) elucidates the connectional architecture of           3 Project Structure
the brain at the level of axons, while keeping the
                                                                      The core project involves 117 institutions and 500
topography of the whole organ; it results in data sets of
                                                                  researchers from 19 countries. It is organized in 12
several Petabytes per brain, which should be actively
                                                                  Subprojects. Neuroscience Subprojects include:
accessible while minimizing their transport. Thus,
                                                                  Mouse      Brain     Organization,     Human       Brain
ultra-high-resolution models pose massive challenges
                                                                  Organization, Systems and Cognitive Neuroscience
in terms of data processing, visualisation and analysis.
                                                                  and Theoretical Neuroscience. Activities in these
    High-resolution data obtained in post-mortem
                                                                  Subprojects provide insights across all levels of brain
brains supplement information about structural and
                                                                  organization: They will be more and more linked and
functional connectivity as obtained, e.g., by Magnetic
                                                                  integrated into comprehensive models, and tested by
Resonance imaging, acquired from the living human
                                                                  simulation.
brain, but with lower spatial resolution. By bringing
                                                                      Big data analytics and simulation are highly
together different aspects of connectivity in one and
                                                                  challenging and data intensive. Therefore, the Human
the same atlas, it is feasible to combine the advantages
                                                                  Brain Project embraces ICT solutions. These include
of the different approaches, and to address the different
                                                                  cloud-based collaboration and development platforms,
spatial (and temporal) scales.
                                                                  with databases for metadata and provenance tracking,
2 The Human Brain Project                                         as well as data analytics and compute services, right up
                                                                  to leading-edge supercomputers, neuromorphic
    The Human Brain Project is developing a new                   systems (4), and virtual robots (5). Research and
European research infrastructure. Part of it is the HBP           development in these areas is organized in six
atlas. It integrates information from multiple levels of          Subprojects,      forming       research     platforms:
brain organisation including cellular architecture,               Neuroinformatics, Simulation, High Performance
connectivity, molecular and genetic maps, as well                 Analytics and Computing, Medical Informatics,
results from neuroimaging and physiological studies.              Neuromorphic Computing, and Robotics. In addition,
This atlas is a resource for empirical research, but also         Management and Ethics & Society form two
modeling and simulation. To represent microscopical               Subprojects.
data, it includes the Big Brain as one of its templates               The main IT service infrastructures is represented
(3).                                                              by the Neuroinformatics Platform (NIP) and the High-
                                                                  Performance Analytics and Computing Platform
Proceedings of the XIX International Conference                   (HPAC). Data from patients are being collected and
“Data Analytics and Management in Data Intensive                  analysed in the Medical Informatics Platform (6). The
Domains” (DAMDID/RCDL’2017), Moscow, Russia,
October 10–13, 2017



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so-called COLLAB provides a connection between the               https://education.humanbrainproject.eu/web/hbp-
Platforms, and a uniform entrance point. As a part of            education-portal
the NIP it serves as the main collaboration
infrastructure.                                                  References
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design projects where neuroscientific investigators and              Lippert T.: The Human Brain Project: Creating a
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the Barcelona Supercomputing Centre (BSC) in Spain,
the Consorzio Interuniversitario per le Applicazioni di          [5] Falotico E, Vannucci L, Ambrosano A, Albanese
Supercalcolo per Università e Ricerca (CINECA) in                    U, Ulbrich S, Vasquez Tieck JC, Hinkel G, Kaiser
Italy, the Centro Svizzero di Calcolo Scientifico                    J, Peric I, Denninger O, Cauli N, Kirtay M,
(CSCS) in Lugano, Switzerland, and the Jülich                        Roennau A, Klinker G, Von Arnim A, Guyot L,
Supercomputing Centre (JSC) in Germany.                              Peppicelli D, Martínez-Cañada P, Ros E, Maier P,
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result of the “Pre-Commercial Procurement”: JULIA,                   P, Laschi C, Knoll AC, Gewaltig MO.: Connecting
developed by Cray, and JURON from IBM and                            artificial brains to robots in a comprehensive
NVIDIA. These systems are specifically designed for                  simulation framework: The Neurorobotics
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on training a new generation of young researchers to                 10.1098/rstb.2014.0171
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Young Researchers Events.                                            2;92(3):622-627.                               doi:
    All educational offers are made available through                10.1016/j.neuron.2016.10.033
its                                            website:




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