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    <journal-meta>
      <journal-title-group>
        <journal-title>Biomedical Ontology in Action"
November</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>A CPG-Based Ontology Driven Clinical Decision Support System for Breast Cancer Follow-up</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Samina Raza Abidi Health Informatics Laboratory</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Dalhousie University</institution>
          ,
          <addr-line>Halifax, Nova Scotia</addr-line>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2006</year>
      </pub-date>
      <volume>8</volume>
      <issue>2006</issue>
      <abstract>
        <p>assist the practitioner to make CPG mediated decisions, recommendations and referrals. In order to achieve the above functionality we have seamlessly integrated the CPG with patient data through electronic interface for collecting patient information. The implementation of the system is achieved in three main steps. In the first step we have converted the breast cancer follow-up CPC in electronic format using the Guideline Element Model (GEM). In the second step we use the logic in the conditional statements of the CPG, to develop a domain ontology using Protégé. Finally in the third step the guideline is executed using the execution engine developed in Health Informatics Laboratory at Dalhousie University. The rule authoring and execution modules of the execution engine is used to develop IF and THEN forward rules with a list of decision variables followed by IF part and list of action variables followed by THEN part of the rule and executing them using the patient specific data.</p>
      </abstract>
      <kwd-group>
        <kwd>Breast cancer follow-up</kwd>
        <kwd>clinical practice guideline</kwd>
        <kwd>domain ontology</kwd>
        <kwd>Guideline Element Model</kwd>
        <kwd>clinical decision support system</kwd>
      </kwd-group>
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      <p>Breast cancer is the most common cancer among
women in Canada. Due to recent advancements
in treatment and diagnosis, more women are
surviving breast cancer then ever before and
breast cancer survivors are the most prevalent
female cancer survivor group in Nova Scotia. As
a consequence, the delivery of long-term
followup care, which has traditionally been provided at
the specialized cancer clinics, places a strain on
specialist resources. However, there is evidence
that family physician follow-up of women with
breast cancer who are in remission is a safe and
viable alternative to follow-up in the cancer
centers. Therefore, there is an incentive to the
transfer of breast cancer follow-up care to family
physicians after primary treatment is completed
by specialists. Notwithstanding, the benefits of
such a transfer of services from the tertiary to the
primary care centers the main issue is the
transfer of specialized breast cancer follow-up
care knowledge to family physicians expertise.
In this regard, as a first step, Cancer Care Nova
Scotia has developed a Breast cancer follow-up
clinical practice guideline for use by the family
physicians. Yet, the adoption of the said CPG is
a challenge in the clinical setting.</p>
      <p>We have developed a Clinical Practice Guideline
(CPG) based interactive decision support system
for the family practice setting to guide family
physicians conducting breast cancer follow-ups.
The idea is to computerize the breast cancer CPG
and then operationalize it using patient data to</p>
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