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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Weighted Discriminant Embedding: Discriminant Subspace Learning for Imbalanced Medical Data Classification</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Tobey H. Ko</string-name>
          <email>tobeyko@hku.hk</email>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Zhonglei Gu</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Yang Liu</string-name>
          <email>csygliu@comp.hkbu.edu.hk</email>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
          <xref ref-type="aff" rid="aff3">3</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Copyright held by the owner/author(s). MediaEval'18</institution>
          ,
          <addr-line>29-31</addr-line>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Department of Computer Science, Hong Kong Baptist University</institution>
          ,
          <addr-line>HKSAR</addr-line>
          ,
          <country country="CN">China</country>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>Department of Industrial and Manufacturing Systems Engineering, University of Hong Kong</institution>
          ,
          <addr-line>HKSAR</addr-line>
          ,
          <country country="CN">China</country>
        </aff>
        <aff id="aff3">
          <label>3</label>
          <institution>Institute of Research and Continuing Education, Hong Kong Baptist University</institution>
          ,
          <addr-line>Shenzhen</addr-line>
          ,
          <country country="CN">China</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2018</year>
      </pub-date>
      <fpage>29</fpage>
      <lpage>31</lpage>
      <abstract>
        <p>A model designed for automatic prediction of diseases based on multimedia data collected in hospitals is introduced in this working notes paper. In order to perform the automatic diseases prediction eficiently, while using as few data as possible for training, we develop a two-stage learning strategy, which first performs the weighted discriminant embedding (WDE) to project the original data to a low-dimensional feature subspace and then utilizes the cost-sensitive nearest neighbor (CS-NN) method in the learned subspace for disease prediction. The proposed approach is evaluated on the MediaEval 2018 Medico Multimedia Task.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>INTRODUCTION</title>
      <p>Aiming at improving the eficiency of detecting medical
abnormalities in the machine intelligence assisted medical diagnosis,
and using as little information as possible, the MediaEval
2018 Medico Multimedia Task [3] seeks to design an
integrated approach to assist the medical experts’ decision-making
process using a combination of video and image information,
as well as other sensory information. In this paper, a two-stage
learning strategy is introduced to facilitate eficient
detection of diseases using multimedia and sensory information.
The first stage consists of a dimensionality reduction process
which projects the original data to a low-dimensional
feature representation using weighted discriminant embedding
(WDE), which improves the eficiency of the learning process
while also preserving the key discriminant information of
the original data. Then, the cost-sensitive nearest neighbor
(CS-NN) method is employed to make the prediction in the
learned subspace.</p>
    </sec>
    <sec id="sec-2">
      <title>WEIGHTED DISCRIMINANT</title>
    </sec>
    <sec id="sec-3">
      <title>EMBEDDING</title>
      <p>Let  be the training set:  = {(x1, 1), · · · , (x, )}, where
x ∈ R ( = 1, ..., ) denotes the feature representation of
the -th sample,  ∈ {1, · · · , } denotes the label of x, 
denotes the number of data samples in the set,  denotes
the number of classes, and  denotes the original
dimension of data. Given the training set, weighted discriminant
embedding (WDE) aims to learn a transformation matrix
W ∈ R×  ( ≤ ), which is capable of projecting the
original high-dimensional data to a low-dimensional subspace
 = R, where the weighted discriminant information could
be preserved.</p>
      <p>In this year’s Medico task, the sample numbers in diferent
classes are highly imbalanced. To enhance the algorithm’s
power in making correct detection on rarer classes, we expect
that data samples belonging to the same class, especially for
the rarer class, should be close to each other as much as
possible in the learned subspace, while nearby data samples from
diferent classes, again, especially for rarer classes, should be
separated from each other as much as possible in the learned
subspace.</p>
      <p>To minimize the weighted intra-class scatter, we present
the following objective:</p>
      <p>
        W = arg min ︁( ∑︁  W (x − x )(x − x ) W︁) , (
        <xref ref-type="bibr" rid="ref1">1</xref>
        )
      </p>
      <p>
        W ,=1
where  = ( +  )/2 if  =  ; and 0 otherwise. Here 
indicates the importance of class  and is defined using the
entropy-based formulation [2]:
 = −
(1 − )2

log(),
where  denotes the proportion of class  in the dataset. In
Eq. (
        <xref ref-type="bibr" rid="ref2">2</xref>
        ), small proportion indicates high importance. Eq. (
        <xref ref-type="bibr" rid="ref1">1</xref>
        )
could be rewritten as:
      </p>
      <p>W = arg min (W LW),</p>
      <p>W
where L is a Laplacian matrix [1] defined as L = D −
A, with D being a diagonal matrix defined as ( ) =
∑︀=1() ( = 1, · · · , ).</p>
      <p>Similarly, we define the following objective function to
maximize the weighted inter-class scatter:</p>
      <p>W = arg max ︁( ∑︁  W (x − x )(x − x ) W︁) , (4)</p>
      <p>W ,=1
where  =  ( +  )/2 if  ̸=  ; and 0 otherwise. Here
 = (−‖ x − x ‖2/2 2) is utilized to measure the
closeness between two data samples. Eq. (4) could be rewritten
as:</p>
      <p>W = arg max (W LW), (5)</p>
      <p>
        W
where L = D − B, with D being a diagonal matrix
defined as ( ) = ∑︀
=1() ( = 1, · · · , ).
(
        <xref ref-type="bibr" rid="ref2">2</xref>
        )
(
        <xref ref-type="bibr" rid="ref3">3</xref>
        )
For a high-dimensional data sample x, it can be mapped to
the subspace by y = W x.
      </p>
      <p>
        We integrate Eqs. (
        <xref ref-type="bibr" rid="ref3">3</xref>
        ) and (5) to form a unified objective
function of WDE:
      </p>
      <p>W = arg max</p>
      <p>W
︂(</p>
      <p>W LW )︂
W LW
.</p>
      <p>Then the optimal W that maximizes the objective
function in Eq. (6) is composed of the normalized eigenvectors
corresponding to the  largest eigenvalues of the following
eigen-decomposition problem:</p>
      <p>Lw =  Lw.
(6)
(7)
3</p>
    </sec>
    <sec id="sec-4">
      <title>RESULTS AND ANALYSIS</title>
      <p>To evaluate our approach, we test its performance on the
MediaEval 2018 Medico Multimedia Task. The task contains
both development set (with 5, 293 samples) and test set (with
8, 740 samples). For each sample, we use six types of features:
the 168-D JCD feature; the 18-D Tamura feature; the 33-D
ColorLayout feature; the 80-D EdgeHistogram feature; the
256-D AutoColorCorrelogram feature; and the 630-D PHOG
feature. The totally dimension is 1, 185.</p>
      <p>We participate in two subtasks: 1) Classification of diseases
and findings; and 2) Fast and eficient classification. For both
tasks, we submit 5 runs.</p>
      <p>from the development set for training;
∙ For Run 1 (on both subtasks), we use all the data
∙ For Run 2 (on both subtasks), we randomly select
50% data for each class from the development set
for training;
∙ For Run 3 (on both subtasks), we randomly select
50% data for each class from the development set,
together with the remaining data in the
“out-ofpatient” and “instruments” classes, for training;
∙ For Run 4 (on both subtasks), we randomly select
25% data for each class from the development set for
training;
∙ For Run 5 (on both subtasks), we randomly select
25% data for each class from the development set,
together with the remaining data in the
“out-ofpatient” and “instruments” classes, for training.</p>
      <p>In the training stage, we use the training data to learn
the transformation matrix W via WDE. We set  = 1 and
the subspace dimension  = 50. In the test stage, we use the
obtained W to map both training and test data to the 50-D
subspace, and then use the cost-sensitive nearest neighbor
(CS-NN) method for the nfial classification in the learned
subspace, where the cost of misclassifying the data of class
 ( = 1, · · ·</p>
      <p>, ) to other classes is defined as  = /,
with  and  being the total number of the training data
and the number of data in class , respectively.
task 1 and subtask 2, respectively. Although the accuracy
looks good, the overall performance is far from satisfactory as
the results on other four important criteria are relatively low.
4) and that on Run 3 (Run 5), we observe that even we use all
the data from the minority classes (i.e., the “out-of-patient”
and “instruments” classes), the performance is not improved.
The reason might be that the number of data in these two
classes are too small to represent the “real” distribution of the
classes. On possible solution is to employ the oversampling
technology to reasonably and faithfully generate samples for
minority classes.
4</p>
    </sec>
    <sec id="sec-5">
      <title>CONCLUSION</title>
      <p>In this paper, we propose a subspace learning method called
weighted discriminant embedding (WDE), aiming at
discovering the discriminant subspace for imbalanced dataset. After
dimensionality reduction, the cost-sensitive nearest neighbor
is utilized for classification. We plan to extend our work
from two aspects. First, we will generalize our approach to
nonlinear case to enhance its data representation ability.
Second, we will incorporate some oversampling methods into
our approach to make it stronger for imbalanced learning
problem.</p>
    </sec>
    <sec id="sec-6">
      <title>ACKNOWLEDGMENTS</title>
      <p>This work was supported in part by the National Natural
Science Foundation of China (NSFC) under Grant 61503317, in
part by the General Research Fund (GRF) from the Research
Grant Council (RGC) of Hong Kong SAR under Project
HKBU12202417, and in part by the SZSTI Grant with the
Projct Code JCYJ20170307161544087.</p>
    </sec>
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