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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Applications of pervasive computing and mobile services in health care</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Vladimir Aleksov</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Snezana Savoska</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Vladimir Trajkovik</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Faculty of Electrical Engineering and Information Technologies, University “Ss Cyril and Methodius” - Skopje</institution>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Faculty of Information and Communication Technologies University „St.Kliment Ohridski“ - Bitola</institution>
          ,
          <addr-line>7000,ul. Partizanska bb</addr-line>
          ,
          <country country="MK">Macedonia</country>
        </aff>
      </contrib-group>
      <fpage>29</fpage>
      <lpage>41</lpage>
      <abstract>
        <p>The massive penetration of mobile devices into the everyday life's actions was made possible by the tremendous growth in the emerging computation paradigm called pervasive computing. This approach envisions a conglomeration of small smart devices as sensors, signal conditioners, wearable computers, mobile phones, tablets, notebook computers, hand-held devices etc. seamlessly integrated and scattered in the environment, according to IoT concept. Pervasive health care focuses explicitly on the use of pervasive computing technology for developing tools and procedures that put the patient at the center of the health care process. From a technological stand point, it includes remote monitoring, remote consultation, and assistive technologies. The main focus in this paper is presentation of our approach in design of these complex distributed systems as a part of improved patient's conditions for living</p>
      </abstract>
      <kwd-group>
        <kwd>Pervasive computing</kwd>
        <kwd>mobile devices</kwd>
        <kwd>SOA</kwd>
        <kwd>Health Pal system</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Life expectancy today tend to increase in many places around the world. The
number of chronic diseases increasing all the time and they have to be address
as earliest as is possible, in order to ensure optimal treatment. One example is
that the difference in cost between well-monitored and badly monitored diabetic
patients is reported to be 2000 per year. Many attempt are made in this direction
proposing some models for improvement healthcare systems despite of decreasing
the number of medical practitioners in some areas [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. The demands for medical
advice grow because the people become aware of the importance of the health
conscious, but they do not want to spend more time at health centers or hospitals.
This fact lead to increasing overall cost for healthcare [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ].
      </p>
      <p>
        One of the possible solutions for improvement of patient’s health care is to set
up health and patient management systems that provide continuous monitoring
of some vital signs, allowing ubiquitous medical treatment and advise patients at
minimum cost. Continuous monitoring is required to obtain a better understanding
of the key medical variables by increasing the measuring frequency. Thus, trends
and historical data can allow more accurate analysis of abnormal values. Today,
telemedicine enables permanent access to medical knowledge and reduces the
cost due to improved efficiency [
        <xref ref-type="bibr" rid="ref3 ref4">3, 4</xref>
        ]. It also increases patients’ quality of life
since people feel safer and their lives become more independent from stationary
treatment. The concept tends to be some kind of ambient assisted living [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ]
helped by the cloud concept, with purpose to send some data to some e-health
providers in order to increase the patient control [
        <xref ref-type="bibr" rid="ref7 ref8">7, 8</xref>
        ] by the medical practitioner
in distance.
      </p>
      <p>
        As computing technology is in a state of continuous evolution, there is a many
new emerging trends that can change the healthcare systems [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ]. One of them
as the state of the art computing paradigm is called pervasive computing, that
envisions a conglomeration of small smart devices as sensors, signal conditioners,
wearable computers, tablets, mobile phones, notebook computers etc. seamlessly
integrated and scattered in the environment. The ultimate goal is to provide some
exciting possibilities in the health care sector neither for diagnostic equipment
[
        <xref ref-type="bibr" rid="ref10">10</xref>
        ] as well as communication devices.
      </p>
      <p>
        Pervasive health care focuses mainly on the use of pervasive computing
technology for developing tools and procedures that put the patient “at the
center” of the health care process. From a technological view, it includes remote
monitoring, remote consultation, and assistive technologies. This provides
exciting possibilities in the health care sector neither for diagnostic equipment
or communication devices [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ]. Contemporary telemedicine systems have
sufficiently advanced so as to relay the medical data over large distances within
a reasonable delay. Attempts are being made to develop intelligent wearable
computers that can perform a primary diagnosis and are the part of a concept
Internet of Things [12, 13].
      </p>
      <p>This paper explains our approach in designing a system named “Health
Pal”information system that uses ubiquitous devices and provide constant monitoring
of patients vital signs as temperature and heart rate in a critical postoperative
period after they’ve being sent to home care. The number of selected vital signs,
measured by different appliances and connected to the mobile systems is not
limited, so they do not overload the proposed concept.</p>
      <p>The first section of the paper analyze the proposed Health Pal System. After
that, Health Pal module for mobile device are analyzed taking into consideration
detailed use case diagrams for different scenarios in the application. The next
section provides analysis of the service module of the Health Pal application
with use cases of all scenarios envisioned. The fourth section explains Inpatient
care module that have to provide the representation of the data received from
sensors for medical staff alert. Fifth section provide some clarification of SOA
Health Pal System design taking into consideration deployment diagram and
sequence diagram for the system. Conclusion remarks highlights some point of
the proposed Health Pal system and some proposal for improvements.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Health Pal System Analysis</title>
      <p>A pictorial overview of the pervasive health care scenario is given on Fig 1.
The requirements for this kind of system are the following: accurate and timely
notification of the medical staff for the trend and the most recent condition of
the patient by reading its vital signs. The medical staff should get the readings
in the appropriate easy readable format, taking into consideration the level of
importance, attached to them. This system have to empower the medical staff to
convey messages to the patients with different severity, depending on their most
recent condition. Having in mind the sensitivity of this data, the system should
have a high level of security and preserve the privacy of each patient. It should
be open also for third party systems (i.e. emergency care notification, research
institutes etc.) that might require this kind of data and enhance the medical care
provided to the patient.</p>
      <p>These requirements can be implemented using distributed system and service
oriented design approach, enabling greater flexibility platform wise as well as
device wise. It have to provide also decoupling of all different parts in the system.
In this solution, the patient’s temperature and heart rate as well as its location are
monitored. The other vital signs as ECG, blood pressure and respiratory flow are
not taken into consideration because of sensor availability issues.</p>
      <p>The Health Pal system consists of three separate application modules and a
sensor module consisted of body temperature sensor and a heart rate sensor. The
first module is an application for a mobile device or tablet that will gather and
send sensor’s data readings to the other parts of the system. The second module
is service oriented application (SOA) that gather the data, process and send it to
the medical staff or third party users. The third module is an application used by
medical staff in order to get the processed data and allow feedback messages to
be sent to the patients according to their most recent condition.</p>
    </sec>
    <sec id="sec-3">
      <title>3. Health Pal Module for Mobile Devices (HPMMD)</title>
      <p>HPMMD module provides sampling the sensor values and send them to the
service application. It should also give an appropriate notation as sound and visual
notifications to the patient when feedback message from the doctor is received. It’s
very important when an abnormal reading from the sensors occurs and application
sends a prompt notification through the system to the medical staff. Having this
in mind it can be conclude that the application needs to have easily configurable
set of values that the sensor readings will be compared against (normal body
temperature and heart rate). The sampling times as well as data sending times
should be also configurable so the application can be flexible to different medical
cases with various examination needs, flexible to the network capabilities that
they send the data through. Another requirement in this kind of application is that,
together with the sensor readings, it also sends the actual position of the patient
with purpose if there is life threatening situation, the medical staff can promptly
send an emergency vehicle to the place where the patient is located. Fig. 2 shows
a detailed use case diagram for the possible scenarios in the application.
 sample temperature sensor readings – get the value shown from the
sensor in one minute intervals
 calculate mean value – calculate mean value of all temperature readings
in one preconfigured sending interval
 sample heart rate sensor readings – get the value shown from the
heart rate sensor in one minute intervals
 check value range – compare the heart rate reading against the
preconfigured “normal heart rate” value range. In case the current value
is out of this range the system should be notified
 read GPS and accelerometer – get the current global position reading
from the internal GPS in the mobile phone or tablet and the accelerometer
reading to show patients position and movement
 send to WCF service - create a package with all the information
(temperature, heart rate, position and movement) and send it to the WCF
service for further processing
 process message – when a return message is received its importance
indicator should be checked
 notify patient – depending on the message’s importance the patient is
notified with a visual, sound or both signals and the message is displayed
Not every sensor reading is sent because of the fact that may cause an
information overload since neither the temperature nor the heart rate, in normal
conditions are expected to fluctuate much. Instead mean values in a predefined
period of time are sent through the system if the values are in the “normal range”
and the current readings are sent if any of the parameters are out of this range.</p>
      <p>In order to ensure a consistent and reliable data through the system this
application send test signals between every batch of sensor data. If there is a
network or processor failure in any part of the system it can be detected in a timely
manner and the patient will not be left unmonitored for a longer period of time.
These test messages (signals) should be sent twice in between two consecutive
data batches and an error will be raised if two consecutive test messages are
not propagated through the system. Test messages will be sent in point of time t
which equation is shown below:
t = nT/3+α
(1)
n = 1,2.. – signal number
T – interval for sending sensor data batches
α – provisional time difference</p>
    </sec>
    <sec id="sec-4">
      <title>4. Analysis of the Service Module of Health Pal System (SMHPS)</title>
      <p>SMHPS module is the central part of the whole system. It handles all
communications between the various applications and provides data for all of
them. That kind of interoperability requires a flexible and platform independent
application. The module receives the data packages sent by mobile device,
processing and storing data into database. It also notifies the appropriate medical
staff about the latest patient’s condition. If there is life threatening readings from
the sensors, the application should immediately communicate with the emergency
service. All depersonalized data from patients that give a consent to share their
information, have to be available to accredited research institutions. Having these
entire requirements in mind, the conclusion is that the best scenario is to build
application as SOA with possibility to communicate across different platforms.
The best way to achieve that kind of interoperability is if SOAP messages are
used.</p>
      <p>Fig. 3 shows the detailed use case diagram for this and all scenarios
envisioned.</p>
      <p> read data – get the data package passed from mobile device and read its
contents
 check value range – compare the passed data points with a predefined
set of “normal values”. The predefined set of “normal values” should be
individual for every patient and configurable by the medical staff at will
 notify emergency – if a data point that shows a life threatening situation
for the patient is received, emergency service should be notified with all
information available (patient information, latest sensor readings and
position)
 send message to medical staff – a notification with appropriate data and
importance attached to it are sent to the medical staff. The importance
depends on the information in the latest data package received
 update database – the latest data is inserted into the database
 convey doctor’s message to patient – the message sent from the doctor
or the medical staff is sent to the appropriate mobile application to notify
the patient if he/she need to take some actions according to his/hers
latest readings
 3rd party users – these users (i.e. research institutions, patients etc. )
after they’ve been given appropriate credentials can log in to the system
and ask for information. After the database is searched they get the data.</p>
    </sec>
    <sec id="sec-5">
      <title>4. Health Pal Inpatient Care Module (HPICM)</title>
      <p>HPICM provides visual representation of data received through the sensors and
prompts notifications. It provides an interface for the medical staff enabling them
to send messages to the patients and configure the “normal” values and sampling
times. Notifications about patients’ data can be sent to this application or to a
designated member of the medical staff through different means (i.e. SMS, MMS,
email etc.)</p>
      <p>Fig. 4 shows a detailed use case diagram of this application and is explained
in detail below.</p>
      <p> get notification message – receive message from the service containing
patients’ data
 notify medical staff according to severity – depending on the
importance level of the received message send a notification to a member
or multiple members of the medical staff assigned to the appropriate
patient. This message can be visual on screen message, SMS, MMS,
email or voice message depending on the importance with a proper
representation of the data.
 send message to the patient – through an interface members of the
medical staff should be able to send a message to the patient regarding
his/hers latest condition and advise him/her on which further actions to
take</p>
      <p>HPICM is a terminal application designed specifically for this purpose or
a part of an already existing application. Having in mind that this paper focuses
on a system that is designed to deal with patients that are in their postoperative
period, we can assume that they’ve already been into the medical facility and
are in some shape or form present in its system. With that assumption we can
consider this application to be a part of already existing application as an added
functionality. It will be referred as an inpatient care application1.</p>
    </sec>
    <sec id="sec-6">
      <title>4. Health Pal System design</title>
      <p>Health Pal is a distributed system with service oriented architecture. The system
is consisted of number of appliances with temperature and heart rate sensors,
connected to mobile devices, a web service and a number of working stations with
running applications or entire systems that have to use these information. Sensor
are connected through Bluetooth to mobile devices. Mobile applications gather
sensor readings process and send them to the web service through the Internet.
The web service is responsible for feeding information to the other parts of the
1 inpatient care application is a common term used for in-house applications used by medical
facilities for keeping track of patients’ information
system. It can send messages to some working stations in the medical facilities
through MMS, SMS or email. It can also communicate to other applications
through SOAP messages regardless of the platform and programming language
that they are built on. The deployment diagram of the whole system is shown on
Fig. 5.</p>
      <p>The information flowing through the system is very sensitive and private so
a high level of security is implemented.</p>
      <p>The sequence diagram on Fig. 6 shows the relationships and data flow
through the system. As it’s portrayed the sensor values are asynchronously read
through the time, to insure continuous monitoring of the patient. These readings
are spaced in 1 minute intervals for both types of sensors, body temperature and
heart rate. In normal circumstances both of these vital signs shouldn’t change
a lot in very short periods of time so sending every single reading through the
system can cause a lot of unnecessary information to be delivered to the medical
staff and a lot of network traffic. That is why the mobile applications have a
configuration option for the sending intervals. For this purpose, the time interval
can be preconfigured in 30 minutes, calculating the mean value of all readings
and then creates a message that have to be sent to the web service. This message
contains the mean heart rate and body temperature in the last 30 minutes, the
current position and the accelerometer reading. Every reading from the sensors
is compared to the “normal values” range which is also configurable to reflect
the needs of every individual patient. This configuration option is available to
the medical staff to change it remotely, flexible to every change of patient’s
condition. If a read value is out of this “normal” range, either heart rate of
temperature, a message with only the current readings and GPS position is sent to
the web service. This ensures a prompt notification to the system if the patient is
experiencing problems. Right after this notification is sent to mobile application,
it does one more sampling to ensure that the last readings are consistent and it’s
not just a temporary malfunction from the sensors. If a malfunction is discovered
(the readings are normal again) a cancelation of the previous alert is sent.</p>
      <p>When the web service receives the data through one of its methods checks the
values against the “normal” range to determine if it is an emergency situation, just
a minor offset from the “normal” values or everything is fine with the patient. The
values are saved into database for monitoring purposes. If emergency readings are
received, the web service sends a notification to an emergency care center with
the appropriate information. This notification contains patient’s personal data, GPS
position for easier tracking and latest vital signs readings. If in the meantime the web
service receives an alert cancelation from the mobile application, is also sent to the
emergency care center, flagged in database as bad data for maintenance purposes.
The whole package of patient’s data is also sent to the inpatient application as
a notification of the medical staff. This web service also provides methods that
make this data available for third party users (research institutions, other medical
applications etc.). They have to have appropriate credentials to be able to extract
data from the system and their access is limited only to the data from the patients
that give a consent to share their data for research and some specific purposes.</p>
      <p>Other applications and application modules can also use the information
and services that the Health Pal web service provides. One typical example is
the inpatient care application. This part of the system delivers the notification
of the patent’s most recent condition to the medical staff. For this purpose the
application has different modes of data presentation (graphs, tabular etc.) and
different kinds of attracting users’ attention (as sound, pop up messages etc.). The
notification messages with the highest importance use sound and visual methods
to get one’s attention and as the severity of the notification declines, the number
of used notification methods decrease. This means that if there is no problem
with the patient’s readings, the medical staff will latter deal with the patient’s
condition due to the obligations with other patients and administrative work. The
application also has an interface for medical staff to send messages to a patient
and to inform him/her about his/hers latest condition and what step or measures
should be taken. It allows a direct communication with the patient and enhances
his/hers confidence. The inpatient care application has an interface that can
change the configuration settings to every single mobile application at will. This
option allows to the medical staff to change the notification periods and “normal
values” range remotely, so every patient can be monitored according to its latest
condition and therapy. In this way, if the patients getting better and do not have
problems, he/she can be monitored less frequently opposed to the ones that have
more difficult recovery and require more frequent monitoring. These changes are
also reflected in the web service.</p>
    </sec>
    <sec id="sec-7">
      <title>6. Conclusions</title>
      <p>The paper considers an aspect of solving some problems connected with improving
patients’ condition of live with usage of pervasive computing and mobile services
in health care services. Having in mind the cost of in-clinic recovery an off-site
healing process, cost-effective methods are proposed. The rehabilitation of the
patient in the comfort at home has proven as a very productive method for the
patients because of the psychological factors. But they still have to be monitored.</p>
      <p>This is the reason why the Health Pal system was designed. Its purpose is
to provide accurate and convenient monitoring of patient in their post-operative
period and reduce the costs in these process. Reduced costs can cause greater
availability of the health care to the people and a better health care system in
general, connecting data with other health care application and alert system
that send information to dedicated medical staff. The model is appropriate also
for short (or long) time monitoring of vital signs at home for the peoples with
disabilities, elderly people, children and remote patients. Health Pal application
uses mobile devices equipped with mobile application and sensors that provide
a vital sign data for the patient. The number of possible sensor is not limited on
the mentioned ones. Taking into consideration the Internet of Things concept,
the possible medical devices connected through mobile applications, there is
increasing trend of their usage in time, decreasing the price of used devices.
The medical practitioners embraces the concept and goes toward accepting the
concepts of telemedicine and e-health, that have to provide better health care
services for the wide range of patient who don’t have appropriate health care,
especially in the area of lack of medical staff as well as the distance location. For
this reason, the application as Health Pal are desirable for medical institutions. The
lack of medical staff will increase the usage of such application using pervasive
and mobile technology connected with SOA.
12. Olivera Kotevska, et al, “Towards a Patient-Centered Collaborative Health Care System
Model”, 4th IEEE International Conference on Computer Science and Information Technology
(IEEE ICCSIT 2011), Chengdu, China, June 10-12, 2011, pp. 562-566
13. Rahmani A.M. and all, Exploiting smart e-Health gateways at the edge of healthcare
Internetof-Things: A fog computing approach, Future Generation Computer Systems, Volume 78, Part
2, January 2018, Pages 641-658, https://doi.org/10.1016/j.future.2017.02.014</p>
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