=Paper= {{Paper |id=Vol-2472/p9 |storemode=property |title=A comprehensive solution for psychological treatment and therapeutic path planning based on knowledge base and expertise sharing |pdfUrl=https://ceur-ws.org/Vol-2472/p9.pdf |volume=Vol-2472 |authors=Samuele Russo,Christian Napoli }} ==A comprehensive solution for psychological treatment and therapeutic path planning based on knowledge base and expertise sharing== https://ceur-ws.org/Vol-2472/p9.pdf
       A comprehensive solution for psychological
    treatment and therapeutic path planning based on
          knowledge base and expertise sharing
                                                  Samuele Russoa and Christian Napolib
                                      a Advanced specialization student, University of Palermo

                                               Piazza Marina 61, Palermo 90133 PA, Italy
                                                      samuelerussoct@gmail.com

                         b Department of Mathematics and Computer Science, University of Catania

                                             Viale Andrea Doria 6, Catania 95126 CT, Italy
                                                         napoli@dmi.unict.it


   Abstract—The healthcare systems are nowadays going trough                 testing among different patients. Moreover trough standardiza-
a broad standardization process so that the caregivers are guided            tion the caregivers are guided in making decisions regarding
in making decisions regarding the diagnosis and the therapeutic              the more appropriate therapeutic plan for a specific conditions,
plannning. Differently from other fields of medicine, psychology
does not base its protocol on drugs and prescription, and neither            while the medical practices can be rationalized improving, in
on standard surgical procedures. In this work we present a                   the end, the general outcome for the therapy at full advantage
software solution to support psychologists during their decision             of the patient’s well being.
making process, helping them both during the diagnosis and the                  Unfortunately for several field of healthcare standardization
treatment of psychological patients. The developed software is               is not easily feasible and sometimes even impossible due to the
structured as a twofold application: it returns a set of clinical
decision rule starting from the definitions contained on the                 extreme variability of the human subjects and their afflictions.
Diagnostic and Statistical Manual of Mental Disorder, but joining            Differently from other fields of medicine, psychology does
the approach with a consensus-based clinical practice oriented               not base its protocol on drugs and prescription, and neither
approach. The first is realized by applying knowledge base to the            on standard surgical procedures. It follows that, while the
research of well structured standard practices, while the second             diagnostics assessment of a psychological patient is based
is obtained by means of expertise sharing from a network of
psychologists. This latter characteristic not only allows us to share        on well standardized tests and observations, the therapeutic
experiences and tips among expert operators, but also to integrate           plan, while grossly defined, must be adapted to the peculiar
a scoring and evaluation system for to guide the choice of the user          personality and characteristics of each patient. It follows that
among comparable practices. The prototype has been tested and                a psychological treatment and its therapeutic path plan must
highly appreciated with an overall 96% of good evaluations. We               mainly rely on the therapist experience and knowledge of
believe that such a support could build the basis of an entire set
of support software tools for medical and psychological diagnosis            similar scenario.
and treatment.                                                                  On the contrary many other fields of medicine can rely
   Index Terms—component, formatting, style, styling, insert                 on very effective clinical prediction rules in order to reduce
                                                                             the uncertainty inherent the medical practice by defining how
                         I. I NTRODUCTION                                    to use clinical findings to make predictions [1]. Clinical
   In the recent years the field of medicine and healthcare                  prediction rules are derived from systematic clinical observa-
have gone trough a broad standardization process by means                    tions. They can help physicians identify patients who require
of therapeutic protocols and standard procedures to be applied               diagnostic tests, treatment, or hospitalization [2].
by physicians, caregivers and healthcare operators in general.                  We can define a clinical decision rule as a decision making
Obviously the introduction of standard protocols helps both                  tool that is derived from original research and incorporates
the physician and the patients by means of a well scheduled                  variables from the history, physical examination, or simple
and well experimented and refined therapeutic path.                          tests [3]. In [4] the development process of clinical decision
   While standardization comes with a price, since it results                rules has been originally described.
in a lack of customization for the developed therapy, it also                   On the other hand clinical decision rule must be based on
presents great advantages in terms of comparability and results              evidences, when no evidence-based guideline exists, i.e. due
                                                                             to the extreme variability of a disease, then a consensus-based
©2019 for this paper by its authors. Use permitted under Creative            clinical practice guideline is the best option [5]. This latter
Commons License Attribution 4.0 International (CC BY 4.0)                    is often used for psychological treatments planning, sometime

                                                                        41
also along with more orthodox clinical decision rules. Finally,          acute headache and demonstrate that their best bedside de-
it must be said that in certain cases it is uttermost difficult          cision rule identified all cases of subarachnoid hemorrhage
to draw methodology-proof clinical practice guidelines due to            among emergency department patients presenting with new,
the extreme statistical and subjective variability of the matter         isolated headaches. In [22] uses fuzzy decision-making rules
at hand [6].                                                             adapted to classification problems by using the methodology
   It follows that physicians, therapists, psychologists, and            of exploratory analysis followed by unification of particular
caregivers in general could obtain great advantages from                 decision rules into fuzzy groups. The fuzzyfication of such
specific support systems in order to be informed of the existing         rules in facts can introduce an ‘useful randomness which is
decision making rules. When such rules are not available it              often the key requirement for a large point of view often
could be of great use to be made aware of the common clinical            required in differential diagnosis. In facts shown in [23] several
decision rules at hand. On the other hand, end especially in this        ambiguous pathological conditions can lead to the possible
latter scenario, extreme benefit is reached by communicating             diagnosis of suspected deep venous thrombosis, on the other
with other colleagues to share knowledge and feedback about              hand in this case is the physicians’ judgement that takes over
their clinical practices.                                                the decision rules. Moreover, while many authors tried to
   In this work we present a software solution to support                reach a universal model of diagnostic reasoning [24], ir is
psychologists during their decision making process, helping              common knowledge that the physicians’ personal experiences,
them both during the diagnosis and the treatment of psy-                 skills and diagnostic abilities hold a key role on the decision
chological patients. The developed software is structured as             making process [25]. This latter is also often self-regulated by
a twofold application: it returns a set of clinical decision rule        precise ad well as perfectible psychological mechanisms [26].
starting from the definitions contained on the DSM-5, the                Individuals’ independent judgment as well as common and
Diagnostic and Statistical Manual of Mental Disorders [7], but           shared experiences are therefore the basis for a good diagnostic
joining the approach with a consensus-based clinical practice            process [27], on the other hand such a process cannot neglect a
oriented approach. The first is realized by applying knowledge           minimum standardization requirement which decision-making
base to the research of well structured standard practices,              rules help to fulfill. In facts it has been shown that diagnostic
while the second is obtained by means of expertise sharing               decisions can be generally improved when a decision-making
from a network of psychologists. This latter characteristic              rules are associated with a knowledge-based approach [28].
not only allows us to share experiences and tips among                      From this short survey of the literature it follows that while
expert operators, but also to integrate a scoring and evaluation         therapeutic path planning must be based on a set of codified
system for to guide the choice of the user among comparable              rules, it also retain a paramount dependence from common
practices [8], [9].                                                      knowledge. The first requirement can be fulfilled by using
   The paper is organized as follows. After this brief intro-            techniques such as knowledge base, while the second can
duction, in the following Section III the designed system is             be implemented by means of a customized expertise sharing
described in its constituent parts. In Section IV we will focus          support system. These two aspect have been integrated by the
on the management of the cloud services giving further details           solution that will be explained in the following.
on the resource allocation policies. Finally in Section V we
will report a pilot case study and the obtained results. Finally                         III. T HE DEVELOPED SYSTEM
in Section VI we will draw our conclusions.                                 In Figure 1 a gross schema of the designed system is
                                                                         reported, this is composed by the following components:
                    II. R ELATED WORKS                                      I. Frontend:
   Decision making rules have been adopted since many years                    • Online interface
and with different purposes. E. g. in [10] descision making                    • DNS handler
rules have been developed as a guide for hospitalization                   II. Backend:
of patients presenting community-acquired pneumonia, while                    A. QoS handler
in [11]–[13] decision making rules are adopted to define when                     • Local Search Visibility component (LSV)
x-rays are needed in acute ankle injuries. In facts such a                        • Secure Sockets Layer (SSL)
support tool is often used for trauma treatments and when                         • HTTP caching component
diagnostical imagery is involved [14], [15].
                                                                              B. Cloud VM
   There are many works in literature about the extraction
                                                                                  • Apache service
and formulation of decision making rules. In [16] decision
                                                                                  • Local Storage
making rules have been extracted by means of a decision
                                                                                  • Local cluster cache service
tree [17]–[20] for the diagnostic workup of patients with
                                                                                  • Computing nodes (CN)
Meniere’s disease, vestibular schwannoma, traumatic vertigo,
                                                                                  • Storage Units (SU)
sudden deafness, benign paroxysmal positional vertigo, and
vestibular neuritis. In [21] the authors present the results of               C. Cloud Services
a prospective, cross-sectional study involving patients with                      • Job queque component




                                                                    42
           USER



                                    QOS HANDLER                                                             DISTRIBUTED DB




                                                                                           HTTP                  LOG
                                              LSV                       SSL
                                                                                          caching              HANDLER




                                                                                                                 Local
                                                                                                                storage
            DNS                        NAMESERVER




                                   CLOUD VM

                                                                                          Apache




                                                                                           Local
                                                                          Local           Cluster
                                                                         storage                              Slave
                                                                                          cache                DB




                                   CLOUD SERVICES


                                                                                          Job                 Main
                                                                                         Queque               DB




                                         Fig. 1: Schematics of the developed system.


   D. Cloud Services                                                   granted the ability to execute JavaScript on a browser-like
       • Log handler                                                   application. Although a web browser would have sufficed to
       • Local storage                                                 interface with the online service, we developed a simple ad-
       • Slave database                                                hoc application to oversimplify the interface. In this manner
       • Main database                                                 it is possible to avoid unnecessary distractions during the test
  The components are better described in the following.                execution. Finally a psychologist provided with the necessary
                                                                       credentials can log into the system to administer the test to a
A. Frontend                                                            patient once such a test has been standardized and approved to
  The frontend of the system has been developed by means               be used. The frontend remote client only provides the interface
of the Angular JS [29], [30] framework in order to grant               for the final users.
portability and compatibility with almost all the available
hardware and software systems. In this manner there are no
particular requirements to interface with the developed system,          In the following the backend is described.



                                                                  43
          USER                                                                        AMAZON LEX                   IOT RULE




                                    AMAZON
                                                                                       AMAZON S3                AWS IOT CORE
                                  API GATEWAY




                                                                                    AMAZON KINESIS                 AMAZON
                                                                                     DATA STREAM                  DYNAMO DB

                                                            AMAZON
                                                             POLY


                                                                                                                   AMAZON
                                                                                       AMAZON
                                                                                                                  DYNAMO DB
                                                                                       PINPOINT
                                                                                                                   STREAMS



                                        INTERFACE      CLOUD



Fig. 2: The adopted Amazon Web Services (AWS) configuration and the relative data flow among the different component and
services within the cloud environment
                                                          .


B. QoS Handler                                                         C. Cloud VM
                                                                          The virtual machine when allocated run an Apache servie
                                                                       daemon, in this manner a simple set of queries makes it pos-
   For distributed systems to properly react to peaks of               sible for the user to interact with the system in order to select,
requests, their adaptation activities would benefit from the           extract and store data from and to the base, distributed on
estimation of the amount of requests. We implemented a a               several storage units. Each VM retains on its local storage only
solution to adapt server-side resources on-the-fly. In order to        a portion of the distributed databases, in fact the connection
ensure a minimum level of quality of service (QoS), even               to such a VM depends on the required portion of data and the
when sudden variations on the number of requests arise, a              related operations. The data are then updated connecting with
large number of (over-provisioned) resources is often used,            a a slave database which retain a potentially updated version of
hence incurring into relevant costs and wasted resources for a         the data. Each VM keep trace of the required updates by means
considerable time interval. We wanted to guarantee a minimum           of a local cluster cache, this latter is responsible to signal the
QoS level once the connection has been established by using            necessary global updates to the job queue scheduler.
resource allocation and adaption algorithms.
   Moreover, in order to minimize bandwidth and resources              D. Cloud services
usage we implemented an internal local search visibility                  The cloud resources are allocated both for computational
component (LSV) and an integrated HTTP caching system.                 and provisional purposes. The details on the cloud policies
In this manner the internal research engine can spare the              are given in the following Section IV. The cloud service layer
user a pedant manual search between the existent records.              is responsible for the update and merge procedure between the
Moreover due to obvious privacy and security requirements we           temporary slave databases and the main database. The reason
also implemented a Secure Sockets Layer (SLL) connection               for this double database system is the time required for a global
between the interface and the HTTP caching service. This               update and merge phase, since this latter is extremely expen-
latter maintains a record of headers and tags to index the             sive in terms of time and resources consumption. Therefore it
knowledge base content and speed up the internal research              is more suitable to live store temporary slave DB the updates,
and retrieval of the required information.                             while delegate at scheduled time both the global merging and



                                                                  44
update, and the distribution of shadow temporary copies to the               4) Symptoms do not occur exclusively during the
slave DBs.                                                                       course of schizophrenia or another psychotic dis-
   The users sessions are logged and stored on a local storage                   order, and are not better explained by another
represented by a replicated sql database. The process is                         mental disorder (eg, mood disorder, anxiety dis-
handled by a LOG handler component.                                              order, dissociative disorder, personality disorder,
                                                                                 substance intoxication, or withdrawal).
              IV. T HE CLOUD ENVIRONMENT
                                                                           Since the system has been applied in Italy , given the known
   For this work we took advantage of the Amazon Web                    association between ADHD and impaired performance on neu-
Services (AWS) [31], and particularly on the AWS ECS and                ropsychological tests due to the effects of ADHD symptoms on
S3 service [32] (see Figure 2).                                         speed and performance on a non-verbal intellectual test [34],
   The resource request is provided to the cloud manager                the interface also reports the official guidelines written by the
component which uses the Amazon AWS APIs to effectively                 Italian Society of Infantry and Adolescence NeuroPsychiatry
request the allocation of new virtual machines. The cloud               and approved by many official associations and operator’s
administration is up to the AWS IoT Core taking into consider-          syndicates. Therefore it also reports that the following tests
ation the AWS IoT rule component that determine the policies            are commonly used:
for the Amazon Kinesis Data Stream. The Amazon Kinesis
                                                                             1) Child Behavior CheckList (CBCL) [35]
Data Stream is a real-time streaming service that provides
                                                                             2) Conners Rating Scales (CRS) [36]
event-driven messaging and supports extended microservice
                                                                             3) Disruptive Behavior Disorder Rating Scale
architectures. This latter allows the processing requests trough
                                                                                 (DBD) [37]
the Amazon API Gateway once an admin has been logged and
                                                                             4) ADHD Rating Scale IV [38]
identified trough his credentials by the Amazon Lex component
                                                                             5) SNAP-IV [39]
to access the Amazon S3 service.
                                                                             6) Diagnostic Interview for Children and Adoles-
   In our system design also the database is distributed on
                                                                                 cents (DICA) [40]
the cloud and supported by the Amazon DynamoDB services
                                                                             7) Kiddie-Schedule for Affective Disorders and
that allows data flow by means of the Amazon DynamoDb
                                                                                 Schizophrenia (K-SADS) [41]
Streams component. Data transactions and session state are en-
                                                                             8) Ravens       Standard      Progressive     Matrices
crypted at-rest and securely managed in the high-performance
                                                                                 (RSPM) [42]
and scalable NoSQL datastore offered by DynamoDB. The
Amazon DynamoDB Streams is also able to trigger an AWS                  While the system will shows these guidelines, it will also
Lambda function in order to send notifications, by means of             highlight a note written by a colleague psychologist that says:
the Amazon Pinpoint and Amazon Polly services.                                The DSM-5 manual extends from 7 years to 12 years
   An example of the system in action is provided in the                      the age limit for the comparisons of ADHD related
following Section V.                                                          symptoms.
                                                                        Finally, while the system proposes an high scoring for the
                      V. A CASE STUDY                                   suggested procedures, it also shows tips and comments from
   Let suppose that a psychologist wants to diagnose a patient          other colleagues which commonly positively rated the follow-
with attention deficit hyperactivity disorder (ADHD): a men-            ing advice:
tal disorder of the neurodevelopmental type [33]. When the                    It can be helpful and good practice to associate
psychologist searches the relative keywords on the system the                 the Ravens Standard Progressive Matrices with
ADHD diagnosis will be suggested and associated with the in-                  the Leiter International Performance Scale Revised
formation contained within the DSM-5 diagnostic manual [7]:                   (Leiter-R).
    1) Five or more symptoms of inattention and/or ≥ 5                  Then leading the user to use the Leiter-R test [43].
        symptoms of hyperactivity/impulsivity must have                    While the reported case is only an example, the system has
        persisted for ≥ 6 months to a degree that is                    been tested with the help of 25 psychologists that, after using
        inconsistent with the developmental level and neg-              the developed system, evaluated the overall performances
        atively impacts social and academic/occupational                and utility as an asset for their profession.Figure 3 shows
        activities. Several symptoms (inattentive or hyper-             the results of such a poll that indicated an high degree of
        active/impulsive) were present before the age of                appreciation for the developed solution with 96% of good
        12 years.                                                       evaluations among the overall received scores.
    2) Several symptoms (inattentive or hyperac-
        tive/impulsive) must be present in ≥ 2 settings                                        VI. C ONCLUSION
        (eg, at home, school, or work; with friends or                     In this work we developed a software solution to support
        relatives; in other activities).                                psychologists during their decision making process, helping
    3) There is clear evidence that the symptoms inter-                 them both during the diagnosis and the treatment of psycho-
        fere with or reduce the quality of social, academic,            logical patients. The application offers a set of clinical decision
        or occupational functioning.                                    rule starting from the definitions contained on the DSM-5



                                                                   45
               Fig. 3: Experts’ scoring of the developed system (1 is the lower grade, while 5 is the highest grade).


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