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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Andrea Bolioli[1], Francesca Alloatti[1,2], Mariafrancesca Guadalupi[1], Roberta Iolanda Lanzi[1], Giorgia Pregnolato[3], Andrea Turolla[3] 1</article-title>
      </title-group>
      <contrib-group>
        <aff id="aff0">
          <label>0</label>
          <institution>CELI - Language Technology</institution>
          ,
          <country country="IT">Italy</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Department of Computer Science - Università degli Studi di Torino</institution>
          ,
          <country country="IT">Italy</country>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>IRCCS Fondazione Ospedale San Camillo</institution>
          ,
          <country country="IT">Italy</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>The research project RiMotivAzione aims at helping post-stroke patients who are following an arm and hand rehabilitation path. In this paper we present the RiMotivAzione corpus, the first collection of dialogues between physiotherapists and patients recorded in an Italian hospital and annotated following the RIAS annotation protocol. We describe the dataset, the methodologies applied and our first investigations on relevant features of the dialogue process. The corpus was the basis for the design of a conversational interface integrated with a wearable device for rehabilitation, to be used by the patient during the exercises that he or she may perform independently.1</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1 Introduction</title>
      <p>
        In recent years, computational linguistics and
medical research have started to collaborate in
order to analyze the communication in the
healthcare domain, in particular between clinicians and
patients. From a medical perspective, linguistic
analysis and dialogue modeling can be used to
better understand and potentially enhance
communication in different healthcare settings
        <xref ref-type="bibr" rid="ref11 ref4">(Sen
et al., 2017; Chang et al., 2013; Marzuki et al.,
2017)</xref>
        , as well as to identify "preclinical" or
"presymptomatic" diseases for specific ranges of
patients, e.g. discovering early linguistic signs of
cognitiv
        <xref ref-type="bibr" rid="ref13">e decline (Beltrami et al., 2018</xref>
        ).
      </p>
      <p>
        Natural Language Processing (NLP)
technologies are also used to develop new communicative
tools, e.g. virtual assistants, to alleviate the
burden on medical personnel or shift to a home-based
patient-centered model of care. Through mHealth
(mobile health), for example, people can receive
assistance at home, and monitoring devices can
check the well-being of a person (Sezgin et al.,
1Copyright c 2019 for this paper by its authors. Use
permitted under Creative Commons License Attribution 4.0
International (CC BY 4.0).
2018). A recent review of scientific literature
about Artificial Intelligence and IoT in healthcare
can b
        <xref ref-type="bibr" rid="ref13">e found in (Shah and Chircu, 2018</xref>
        ).
      </p>
      <p>The research project RiMotivAzione aims at
helping the patients who suffered from a stroke
and are following an arm and hand rehabilitation
path. The goal is to motivate the patients to follow
the assigned exercises through the use of a new
wearable device with motion sensors developed by
the Istituto Italiano di Tecnologia (IIT), integrated
with a visual App and a conversational interface.
This last component guides the user through the
therapeutic path proposing the exercises, giving
advice and asking for feedback.</p>
      <p>
        The implementation of voice technologies in the
healthcare domain allows for patients with motor
impairments to interact with devices through
spoken language
        <xref ref-type="bibr" rid="ref5">(Moore et al., 2018)</xref>
        , while arm and
hand are busy performing the assigned exercises.
The interaction is seamless and spontaneous. The
patient can keep up autonomously with the
therapy thanks to the guidance provided by the voice
assistant. The physiotherapist can monitor the
patients at a distance, to evaluate their progress, and
he can prevent a situation of therapy neglect by the
patient, while the latter is motivated to stick to the
path and he can reach his rehabilitation goals on
time. Needless to say, these digital assistants are
not meant to substitute the clinician.
      </p>
    </sec>
    <sec id="sec-2">
      <title>Methodological Background and</title>
    </sec>
    <sec id="sec-3">
      <title>Related Work</title>
      <p>
        As we described in the previous section, the study
of communication and conversation in the
medical domain is growing in the last years, as well
as the introduction of conversational agents in the
healthcare sector. A review of current applications
and evaluation measures of conversational agents
used for health-related purposes can be found, for
example, in
        <xref ref-type="bibr" rid="ref3">(Laranjo et al., 2018)</xref>
        . Otherwise,
there is no systematic review of scientific literature
concerning the linguistic analysis of dialogues in
healthcare. Some scientific studies describe how
communication can influence clinical outcomes in
the rehabilitation setting, e.g. how patient
satisfaction, decision-making, and stress level correlate
with physicians’ communicative acts
        <xref ref-type="bibr" rid="ref2">(Hall and
Roter, 2012)</xref>
        . Some researchers propose methods
to detect and track topics in psycho-therapeutic
conv
        <xref ref-type="bibr" rid="ref13">ersations (Chaoua et al., 2018</xref>
        ). Other
researchers conducted an analysis of actual
communicative behaviors, including nonverbal ones,
between physicians and patients in rehabilitation,
using transcription and coding of utterances (Chang
et al., 2013).
      </p>
      <p>
        The analysis of speech acts and conversational
interaction can play a relevant role in dialogue
modeling for healthcare thanks to the
classification of utterances, the analysis of dialogue turns
and threads, the discovery of recurrent patterns.
Speech acts have been investigated in linguistics
and computational linguistics for long.
Specifically, the task of automatic speech act
recognition has been addressed leveraging both
supervised and unsupervised approach
        <xref ref-type="bibr" rid="ref13">es (Basile and
Novielli, 2018</xref>
        ). Otherwise, in the healthcare
domain there is still much room for investigation.
      </p>
      <p>
        In the RiMotivAzione project, we deal with
physiotherapy sessions in a hospital. The task is
to collect and analyze para-linguistic and
linguistic data, according to the aforementioned goal of
the research project. In this specific setting, i.e.
conversational analysis of physician-patient
discourse, the most widely used method is the Roter
Interaction Analysis System (RIAS). RIAS was
developed as a tagset for coding medical dialogue
since 1991 by Debra Roter et al.
        <xref ref-type="bibr" rid="ref7 ref9">(Roter, 1991;
Roter and Larson, 2002)</xref>
        and it has been
constructed as to be viable for all kind of sessions, e.g.
conversations in the oncological setting (2017),
between patients and psychotherapists or even
patients and pharmacists. Moreover, RIAS was
originally developed to annotate audio, while we
transcribed the speech and annotated the
transcriptions. This is motivated by the NLP analysis we
wanted to perform on the text, e.g. syntactic and
semantic analysis, machine learning, automatic
dialogue act classification. Other dialogue
annotation schemes exist, namely
        <xref ref-type="bibr" rid="ref12">(Bunt et al., 2017;
Serban et al., 2017; Stolcke et al., 2000)</xref>
        , that includes
rich taxonomies of communicative functions. The
ISO 24617-2 standard, for example, includes the
specification of the Dialogue Act Markup
Language (DiAML), used in many annotated corpora.
In RiMotivAzione project, we deemed RIAS as the
most useful one for its specific focus on medical
conversation. Even though RIAS is the closest
domain tagset to annotate our corpus, some problems
still emerged and they will be presented in next
section.
3
      </p>
    </sec>
    <sec id="sec-4">
      <title>Corpus Annotation</title>
      <p>The RiMotivAzione corpus includes two complete
cycles of physiotherapy sessions with two patients
in post-stroke rehabilitation (namely, P1 and P2)
and three physiotherapists (T1, T2, T3). The
interviews were video recorded in IRCCS Fondazione
Ospedale "San Camillo" in Venice. Each session
lasted about 1 hour. The physiotherapy cycle for
patient P1 included 14 sessions, while P2 took 16
sessions. Therefore the total duration of
recordings is about 30 hours.</p>
      <p>The patients were carefully selected by the
doctors, since they must present some features. Above
all, they had to agree to be part of the
experimentation and they needed to talk in Italian. In an
environment where dialect is still strong, their ability
to speak Italian was not to be treated lightly.
Moreover, the patients did not have to present any issues
related to aphasia. These requirements restrained
the viable options to two candidates.</p>
      <p>Both speakers were encouraged to talk freely
about any topic that may have emerged. Their
only constraint was the use of Italian; when
people slipped into dialectal terminology (in this
case, Venetian), it was explicitly marked with
the &lt;dialect&gt; tag in the corpus. The audio
tracks were transcribed and annotated following
Savy’s (2005) guidelines for orthographic
transcription for spoken Italian, where applicable. As
a pre-processing, we used two Automatic Speech
Recognition (ASR) systems, i.e. Google
Speechto-Text and Nuance Transcription Engine.
Automatic transcriptions were corrected manually and
anonymized. Video and audio tracks have been
separately saved for future projects.</p>
      <p>Overlapping between the two speakers and
pauses were not marked, as it was not relevant to
our study. Similarly, any intervention in the
dialogue from a third party was not transcribed since
our interest was solely in the doctor and patient’s
linguistic behaviours. Each dialogue turn of the
corpus was annotated by two different annotators
following the RIAS guidelines. All the annotators
have a background in linguistics and a specific
education about linguistic corpora. As a single
dialogue turn may contain more than one sentence
and more than one speech act, the tags assigned to
each turn may be more than one.</p>
      <p>RIAS tagset includes 29 categories divided in
four macro-categories called Medical Interview
Functions (MIF) that cover the majority of the
exchanges between a doctor and a patient: Data
Gathering, Information Exchange, Emotional
Expression and Responsiveness, Partnership
Building and Activation. Table 1 contains the list of
categories occurring at least 200 times in the
corpus, together with examples.</p>
      <p>To the best of the authors’ knowledge, the RIAS
system has never been used to annotate sessions
of physiotherapy until now. This means that not
all of the tags applied completely to the
situation, or that some tags may be under-represented
compared to other studies: for instance, the tag
Concerns was applied to few sentences, since
patients in physiotherapy sessions may inherently
express less concern than oncological patients.</p>
      <p>
        All the categories
        <xref ref-type="bibr" rid="ref8">defined in Roter et al. (2017</xref>
        )
were used. Moreover, two more tags were
added to include all the exchanges: Unclear and
Technical problems. The first applied to
incomplete sentences, unintelligible ones (also marked
with the &lt;unclear&gt; tag), or even in cases where
the sentence referred to the physical context,
making the general meaning impossible to retrieve for
the annotator. The second tag applied to situations
where the wearable device wasn’t working
properly, therefore resulting in some technical issue out
of the scope of the therapy.
      </p>
      <p>Another issue concerns the use of irony.
Specifically, Patient 2 heavily employed irony while
talking to the therapist, even when the dialogue
concerned his health and well-being. Irony is hard
to interpret, resulting in the difficulty to assign
correctly a tag to those sentences. Tag Jokes
was used in this case, and where inappropriate,
a discussion between the annotators oriented the
choice.</p>
      <p>As the annotation task was difficult and it was
inherently affected by subjectivity, we measured
the resulting inter-annotator agreement and we put
in place strategies to solve the disagreement, in
order to annotate all the dialogue turns. The
agreement calculated at this stage, according to the
Cohen’s score, was promising (k = 0.63). In case of
disagreement (about 25% of the data), the process
was followed by reconciliation or a final decision
by a super annotator, where the two annotators
could not overcome the disagreement.</p>
      <p>The RiMotivAzione corpus has been built and
archived according to GDPR norms. It is not
publicly available but it can be requested to the authors
for research purposes.
4</p>
    </sec>
    <sec id="sec-5">
      <title>Corpus Analysis</title>
      <p>The RiMotivAzione corpus contains about 98778
tokens. The total number of dialogue turns is
7670: 3377 dialogue turns in P1 sessions, 4293
in P2 sessions.</p>
      <p>In Table 2 and Table 3 we reported the number
of types, tokens, the ratio between types and
tokens (the Lexical Richness Index) and the number
of questions for the two patients.</p>
      <p>
        It is worth noticing that Lexical Richness Index
ranges from 0 to 1 and it is closer to 0 in the
doctors’ speech, meaning that medical personnel
employ a poorer vocabulary while talking to a patient.
This is due to the fact that a therapist needs to stick
to a protocol and cannot digress over a certain
limit. On the other hand, the patient talks
quantitatively less: he pronounces fewer words, and
most of the time those words are simple answers
to the questions posed by the clinician. The patient
talks less but he can wander more across
conversation topics: he may disclose some personal detail
about his life or just chit chat. This behavior is
actually encouraged by the therapist, since it makes
the therapy session less dull and more spontaneous
for both the participants
        <xref ref-type="bibr" rid="ref14">(Delany et al., 2010;
Edwards et al., 2004)</xref>
        . To sum up, the doctor needs
to talk a lot to instruct the patients about the
exercise they need to fulfill, as well as to ask
questions (mainly regarding general well-being and
inquiries about the therapy itself). Meanwhile, the
patient may talk less because most of the time he
just has to answer short questions (such as "Does
it hurt?"); or, when he talks more, it is about some
external topic which generates an increment in the
vocabulary richness index.
      </p>
      <p>
        As the main goal of the study is to replicate
the clinician’s communicative style onto a
conversational interface, the major interest is on how
the therapists talk, rather than the patients.
Patients’ manner of speaking is taken into
consideration when imagining all the orders or phrases
that the user could say to the voice assistant to
express his needs. Table 4 and Table 5 list the most
frequent Verbs and Adjectives pronounced by the
physiotherapists. Apart from "Okay", which is the
most frequent word for both therapists (1231 and
1019 occurrences), both therapists often use
adjectives of positive value: bravissimo, bravo, ottimo,
buono. Other frequent words are mainly verbs
expressed at the first plural person, such as we do,
we’ll try, or equivalent expressions (let’s relax).
The use of the "we" is a communication element
that aims at putting on the same level the
clinician and the patient; the goal is to make the
patient feel more comfortable and therefore
enhancing the probability of therapy adherence. At the
same time, adjectives such as "good" and "very
good" praise the patient’s efforts, underlining the
progress he is making. The psychological
component is of paramount importance during
physiotherapy, especially for patients that suffered a
stroke
        <xref ref-type="bibr" rid="ref6">(Palma and Sidoti, 2019)</xref>
        .
      </p>
      <p>The quantitative analysis operated over the
annotated corpus confirms the qualitative remarks
made so far. In Figure 1 we present the distribution
of dialogue tags, both for patients and therapists,
i.e. the distribution of utterance type according
to RIAS categories. We plotted on a logarithmic
scale the frequencies of the tags.</p>
      <p>
        Sentences annotated as Social talk were
abundant, while those marked as Concerns were
copious just for a patient, because he was
frustrated about his health situation and the
difficulties to manage the physiotherapy. During the
sessions with Patient 1, the physiotherapist was able
to engage a conversation about a hobby of his
(motorcycles); even though this discussion topic
is not relevant to the therapy, the fact that they
were talking about something interesting for the
patient contributed to the improvement of his
medical condition
        <xref ref-type="bibr" rid="ref1">(Gard and Gyllenstein, 2000)</xref>
        .
      </p>
      <p>All of these conversational elements are put in
place willingly by the clinician and, even more, it
is the style patients are used to. In the voice
assistant design we try to mirror these strategies,
providing praises when appropriate and asking
questions to constantly monitor the user’s well-being.
The data extracted from the transcription and the
annotation represents the most frequent
linguistic behaviors emerged during the conversations.
These patterns were used to build the
conversational style and infrastructure of the dialogue
system.
5</p>
    </sec>
    <sec id="sec-6">
      <title>Conclusions and Next Steps</title>
      <p>We created a corpus of conversations between
patients and clinicians, in Italian, and we annotated
the dialogue turns according to the Roter
Interaction Analysis System (RIAS). This corpus was the
first step in the design of a conversational
interface integrated with a smart wearable device, to
guide and assist the patients through the exercises
assigned by the physiotherapist.</p>
      <p>The first step in the future work will be to
deepen the linguistic analysis conducted on the
corpus, especially regarding the tagged dialogue
acts. A stronger qualitative investigation over the
data will be carried out. The second step will be
to enrich the dataset: unfortunately, only two
patients were deemed appropriate for the
experimentation, while a corpus should contain dialogues
from more speakers.</p>
      <p>The RiMotivAzione corpus can be requested to
the authors for research purposes.</p>
      <p>The system prototype will be tested in San
Camillo Hospital by a set of stroke patients,
following the clinical trial procedures. Thanks to the
results of the test, we will produce experimental
data to investigate if and how a voice assistant
integrated with a wearable device can increase the
effectiveness of the therapy.
6</p>
    </sec>
    <sec id="sec-7">
      <title>Acknowledgments</title>
      <p>RiMotivAzione is a two-year Research and
Innovation project supported by POR FESR
20142020 Regione Piemonte. The partners are Koiné
Sistemi, CELI, IRCCS Fondazione Ospedale San
Camillo, Synesthesia, Istituto Italiano di
Tecnologia (IIT) and Morecognition. We are thankful to
our colleagues and project partners, in particular
Paolo Ariano and Nicoló Celadon.</p>
    </sec>
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