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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Antibids - Antibiotics Big Data System</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Natalya Shakhovska</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Head of Artificial intelligence department, Lviv Polytechnic National University</institution>
          ,
          <country country="UA">Ukraine</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>Development of decision support clinical system AntiBidS (Antibiotics Big Data System) that will serve to the collection, processing and analysis Big medical data from various sources, to simplify the process of personalizing treatment, standardization of approaches for selecting schemes of antibiotic therapy, to collect the new trends in pharmaceutical products on the Internet. All of them will provide expansion of the social aspect in the work of medical staff and in the health and well-being of patients.</p>
      </abstract>
      <kwd-group>
        <kwd>Antibiotics</kwd>
        <kwd>Big Data</kwd>
        <kwd>System</kwd>
        <kwd>personalizing treatment</kwd>
        <kwd>patient</kwd>
        <kwd>medical data</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>Introduction</title>
    </sec>
    <sec id="sec-2">
      <title>Objectives</title>
      <p>Proposal outline: development of decision support clinical system AntiBidS
(Antibiotics Big Data System) that will serve to the collection, processing and analysis
Big medical data from various sources, to simplify the process of personalizing
treatment, standardization of approaches for selecting schemes of antibiotic
therapy, to collect the new trends in pharmaceutical products on the Internet. All of
them will provide expansion of the social aspect in the work of medical staff and in
the health and well-being of patients.</p>
      <p>•
•
•
•</p>
      <p>Simplify and improve the process of personalization antibiotic
treatment of patients;
Collect information about medications from different pharmacies
databases and automatically parse.</p>
      <p>To allow of doctor find needed medications without remembering all
trade-marks and pharmacies groups.</p>
      <p>Automatically medical e-prescription creation.</p>
      <sec id="sec-2-1">
        <title>Incoming information:</title>
        <p>•
•
•</p>
        <p>Information about the disease
Patient information (medical record with diagnose)
Instruction for medication</p>
      </sec>
      <sec id="sec-2-2">
        <title>Data processing:</title>
        <p>•
•
•</p>
        <p>Medical instruction parsing
The medication (antibiotic) selection
E-prescription creation</p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>The technical approach</title>
      <p>Phase 1. To collect medication instructions





</p>
      <sec id="sec-3-1">
        <title>Indication</title>
        <p>Contraindication
allergic reaction
active substance
dosage
diseases
Graph and document-oriented database combination
CREATE (Ampicilin:Antibiotic {title: Ампіцилін, latin_title: Ampicilin,
release_form: ‘Tablets 500 000 IU',application_method:'Inside of 400,000
500,000 IU 2-3 times a day for 10-12 days'})
CREATE (Candidiasis:Disease {name: Candidiasis gastrointestinal tract'})
CREATE (SkinLesions:Disease {name: Lesion of skin'})
CREATE (MucosalLesions:Disease {name: Mucosal lesions'})
CREATE (Liver:Disease {name: Liver illness})
CREATE (Stomach:Disease {name: Acute gastrointestinal diseases'})
CREATE (Ulcer:Disease {name: Gastric ulcer and duodenal ulcer'})
CREATE (UteineBleeding:Disease {name: Uterine bleeding'})
CREATE
(Candidiasis)-[:INDICATION]-&gt;(Ampicilin),
(SkinLesions)-[:INDICATION]-&gt;(Ampicilin),
(MucosalLesions)-[:INDICATION]-&gt;(Ampicilin),
(Liver)-[:CONTRAINDICATION]-&gt;(Ampicilin),
(Stomach)-[:CONTRAINDICATION]-&gt;(Ampicilin),
(Ulcer)-[:CONTRAINDICATION]-&gt;(Ampicilin),
(UteineBleeding)-[:CONTRAINDICATION]-&gt;(Ampicilin)</p>
      </sec>
      <sec id="sec-3-2">
        <title>Phase 2. Medication selection. An example of a parallel connection of graphs for a system of work with instructions for medical products</title>
        <p>Phase 3. The patient data collection system
The system for processing medical data and predicting the patient's condition
The result of power bands of HRV plotting
Conclusions</p>
        <p>Raising awareness of physicians with new medicines allow decrease in time spent for
searching for information about them.</p>
        <p>Improving the quality of medical treatment by personalizing treatment schemes.
Analysing the efficiency of patient pathway management both at primary care level
(prevention and early detection) and en route encompassing
Ability to use the program not only to antibiotic therapy, but doctors can use for other
fields that will increase the quality of medical care.</p>
        <p>Providing hospitals the proposed information system for the rational antibiotic therapy
for diseases caused by different types of surgical infection.</p>
        <p>Analysis of treatment's results, according to which possible to determine the efficacy of
using the therapeutic schemes and prognostication of next methods of treatments.
The inclusion of large amounts of data into useful information for planning authorities
in the field of public health and implementation approach "health in all policies".</p>
        <p>The intelligence coach increase patient’s well-being.</p>
      </sec>
    </sec>
  </body>
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