=Paper= {{Paper |id=Vol-2931/ICBO_2019_paper_16 |storemode=property |title=Roles and Their Siblings in Basic Formal Ontology |pdfUrl=https://ceur-ws.org/Vol-2931/ICBO_2019_paper_16.pdf |volume=Vol-2931 |authors=Fumiaki Toyoshima |dblpUrl=https://dblp.org/rec/conf/icbo/Toyoshima19a }} ==Roles and Their Siblings in Basic Formal Ontology== https://ceur-ws.org/Vol-2931/ICBO_2019_paper_16.pdf
                                      Roles and Their Siblings in Basic Formal Ontology

                                                                Fumiaki Toyoshimaa
           a
               Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, Nomi, Japan



Abstract                                                                          disease.” Second, healthcare systems would not be completely
                                                                                  accounted for unless their organizational structure is well-
Roles are entities that pervade our everyday life as well as                      specified in terms of roles, or especially so-called ‘social roles’
biologists’ and medical specialists’ actual practice. Their nature                [5,6]. Examples of those medical roles include healthcare
nonetheless remains nebulous in spite of a large amount of                        providers (e.g., doctors and pharmacists), receivers (e.g.,
recent research on it in various disciplines. This paper aims to                  patients), and policy makers (e.g., members of the World Health
provide an in-depth study of the term ‘role’ in alignment with an                 Organization). Therefore, a deeper understanding of roles will
upper ontology Basic Formal Ontology (BFO). Closer                                contribute to a robust construction and an effective utilization of
examination reveals that the meanings of the term ‘role’ can be                   biomedical ontologies.
well disambiguated in terms of five BFO categories: a
generically dependent continuant, a site, a role, a disposition,                  Roles nevertheless remain nebulous entities, although they have
and a function. We also discuss the BFO characterization of role                  been extensively researched in foundational ontology research
and its practical utility in the biomedical field with a focus on its             for the last few decades [7]. For instance, it is a long-standing
relation with the BFO methodological principle of ontological                     issue whether there is any single definition of role, some prior
realism and other BFO realizable entities: dispositions and                       attempts [2,8] to offer it notwithstanding. Moreover, it is still a
functions.                                                                        worthwhile challenge to provide a generic characterization of
                                                                                  multiple meanings of role within a single theoretical framework.
Keywords:                                                                         Despite some endeavors to meet it [9,10], little careful
role, Basic Formal Ontology (BFO), ontological realism                            consideration has been given to a general ontology of roles vis-
                                                                                  à-vis the biomedical domain.
I.      Introduction                                                              In this paper we provide a close ontological investigation into
                                                                                  the meanings of the term ‘role’ with an emphasis its usage of the
Talk of roles is ubiquitous in our ordinary life and in a number                  term ‘role’. To do so, we exploit Basic Formal Ontology (BFO)
of different academic fields, ranging from knowledge                              [3,4] as an upper ontology (aka foundational ontology), namely
representation [1] and conceptual modeling [2] to cognitive                       an ontology to furnish the most general categories (e.g., space
science and linguistics. Several examples of expressions                          and time) and relations (e.g., identity and parthood) to serve as a
comprising the term ‘role’ are listed below:                                      useful guideline for building domain ontologies of high semantic
                                                                                  interoperability. The BFO-based exploration of the term ‘role’
      1.       A passenger plays the role of a pilot on a commercial              would be of great value for biomedical ontologies because the
               plane in an emergency. [3, p. 58]                                  practical utility of BFO to them is shown by the achievement of
      2.       Jane’s being the seventh person to fill the role of                the Open Biomedical Ontologies (OBO) Foundry [11]: a
               director of this institute [4, p. 100]                             collaborative project to coordinate ontologies to support
                                                                                  biomedical data integration such that BFO can provide a
      3.       Joe’s being the third person to play a particular role in a        common semantic basis for all the OBO ontologies.
               play [4, p. 101]
                                                                                  In the most basic BFO framework, entities fall into two kinds:
      4.       A pyramidal neuron plays the role occupied by a                    universals (aka types, classes) and particulars (aka tokens,
               damaged stellar neuron in the brain. [3, p. 58]                    instances). Particulars (e.g., Mary) bear the instance-of relation
      5.       Jim has the role of a nurse. [4, p. 100]                           to universals (e.g., Human). Particulars, on which we place a
                                                                                  primary focus in this paper, fall into two categories: continuants
      6.       the role of a stone in marking a boundary [4, p. 100]              and occurrents. Characteristically, continuants can persist, that is
      7.       the role of a magnet to attract iron objects                       to say, they can exist at one time and also exist at another
                                                                                  different time; whereas occurrents (including processes) extend
      8.       the role of the heart to pump blood                                through time. Continuants can be further divided into
Roles are vital to biomedical ontologies at least in two respects.                independent continuants (including objects) and dependent
First, the term ‘role’ is frequently used in the biomedical                       continuants (intuitively: properties). Independent continuants, or
literature: e.g., “the specific role of calcium in preventing                     especially objects (e.g., stones) can be bearers of dependent

     Copyright © 2019 for this paper by its author. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).
continuants (e.g., hardness) and they can also participate in            of the device, my device is defective relative to the specification
occurrents (e.g., a fall of the stone).                                  of a stack” [14, pp. 16-17]. Quite importantly, Turner considers
                                                                         specifications as intentional: “Our intentional stance determines
For this purpose, we draw upon Toyoshima’s [12] thesis that,
                                                                         what we take to be the specification: something is a specification
based on a detailed analysis of upper ontologies, there are (at
                                                                         if we give it normal force over the construction of an artefact”
least) three closely intertwined notions of role at a foundational
                                                                         [13, p. 147].
level: a role specification, a role position, and a role potential. It
is found on closer examination that those three facets of roles          A role specification refers to a role that is understood by analogy
(and other meanings of the term ‘role’) can be well-defined in           with a specification and role-bearing is interpreted as meeting a
terms of some existing BFO categories. This would also testify           role specification. On this specification view of role, a role-
to the explanatory force of BFO (with regard to roles) as                bearer is to its role what an artifact is to its specification. In this
compared to its relative smallness among upper ontologies.               respect, roles and artifacts are closely linked from a modeling
                                                                         perspective [15]. In the U.S., for instance, an aircraft has to meet
The paper is structured as follows. Section II presents
                                                                         the strict specification laid down by the Federal Aviation
Toyoshima’s [12] argument for three roles. Section III analyzes
                                                                         Administration (FAA). This means that an aircraft-like
from the BFO viewpoint those three aspects of role and other
                                                                         aggregate of mechanical parts is not an aircraft unless it is
possible meanings of the term ‘role’. Section IV discusses the
                                                                         constructed exactly to the FAA specification. Likewise, UB has
BFO notion of role, its connections with the BFO principle of
                                                                         drawn up intentionally its ‘student role specification’ (e.g.,
ontological realism as well as the BFO categories of disposition
                                                                         admission requirements), and Mary fails to be a student (in other
and function, and its practical utility in the biomedical domain.
                                                                         words: to bear a student role) unless she satisfies the UB-student
Section V concludes the paper with some brief remarks on
                                                                         role specification.
future possible directions of research.
                                                                         Despite their striking similarity, a role specification and a
                                                                         specification (resp. a role-bearer and an artifact) differ greatly
II. Three Facets of Roles                                                from each other at least in two points. First, they are temporally
                                                                         different: a role specification and a role-bearer are temporary
Toyoshima [12] examines some preceding accounts of role,                 (time-relative) but a specification and an artifact are permanent
being motivated to know which ontological conception of role is          (time-insensitive). For instance, an American aircraft emerges
suitable for which type of conceptual modeling. He then                  when it is built to the FAA specification and it continues to exist
hypothesizes that different theories of role might depend on             until it is physically destroyed; whereas, Mary is a UB student as
different ‘role choices’ made by the theories: choices as to             long as she meets a UB-student role specification and she can
which is most fundamental among ‘three facets’ of role (which            survive even after ceasing to be a student. Second and
he calls the ‘role triad’), or its three main ontological                connectedly, they are modally contrary: the former are
interpretations: namely, a role specification, a role position, and      contingent (accidental) but the latter are necessary (essential).
a role potential. On his view, the role triad would defy explicit        (Note that, pace Fine [16], we lightly assume throughout this
analysis, but it can be elucidated by analogy and illustrated with       paper a conceptual overlap between modality and essentiality
the question of what it is supposed to mean to say, e.g., that           merely for a practical purpose.) While artifactness (e.g., FAA-
Mary is a student of University at Buffalo (UB), given the fact          aircraftness) constitutes the essence of an American aircraft, for
that a student is taken to be a paradigmatic example of role and         example, roleness (e.g., UB-studentness) is inessential to Mary.
Mary bears a student role, or simply Mary is a role-bearer.              It     must      be     emphasized     that    temporality     and
                                                                         contingency/accidentality are key characteristics of a general
A)   Role Specification                                                  notion of role irrespective of which role choice is taken.
One approach to Mary’s studentness focuses on the deontic or             B)   Role Position
normative dimension of her student role. Mary must gain
admission to UB in order to become a UB student. To enjoy a              Another possibility for understanding Mary’s studentness is
full-time student status, she needs to register for a certain            based on the kind of situation in which Mary bears a student
number of credit hours per semester. She is also required to             role. As a UB student, Mary can use various facilities and enjoy
defend her dissertation to obtain a doctoral degree from UB.             educational opportunities (e.g., taking classes). Mary’s
Mary’s studentness is thus explicable in terms of the satisfaction       studenteness may then consist in the fact that she locates herself
of the constraints or conditions that are, so to speak, ‘embedded’       in a specific ‘sphere’ or ‘position’ where she can do something
in her student role.                                                     role-related.
This observation would lead to an analogy between a role and a           A role as conceptualized this way is analogous with a relative
specification. The ontological nature of a specification remains         place [17]. Given the Newtonian conception of absolute space,
obscure, but Turner [13] maintains insightfully that a                   both absolute places and relative places persist and may be
specification is something that has “correctness jurisdiction over       occupied by various (material) objects at various times. Unlike
an artefact” [13, p. 147]. By ‘correctness jurisdiction’ he means        absolute places (which are parts of absolute space that are
that the specification places “empirical demands on the physical         independent of objects), relative places stand in fixed spatial
device” [13, p. 144]. If an artifact is not built to a certain           relations with one or more objects (reference objects [17]).
specification, the artifact is defective with respect to that            Examples include places in and around a ship whose reference
specification. Duncan [14] illustrates this point as follows: “For       object is the ship.
example, if I build a physical implementation of a stack and the
device does not allow me to add and remove items from the top            A role position means a role that is figured out by analogy to a
                                                                         relative place and role-bearing is construed as occupying a role
position. Seen from this positional perspective, roles stand in         We introduce a fine-grained classification of dependent
fixed ‘conceptual’ relations towards one or more entities, which        continuants for the sake of future argument. In BFO, there are
may be sometimes called ‘context’ in the relevant literature            two kinds of dependent continuants. One is a specifically
[10,18]. (Note that, despite Smith’s [19] warning against               dependent continuant: “A continuant entity that depends on
concepts in ontology research, we are using the term                    precisely one independent continuant for its existence. The
‘conceptual’ in its broad sense as a kind of placeholder. Its           former is dependent on the latter in the sense that, if the latter
precise meaning should be further clarified in the future               ceases to exist, then the former will as a matter of necessity
investigation.) In bearing a UB-student role, for example, Mary         cease to exist also” [4, p. 185]. Examples include the mass of a
occupies the student role position that exists relative to UB.          kidney and the shape of a hand.
The analogy between role positions and relative places would            The other is a generically dependent continuant: “A continuant
shed light on the alleged relational nature of roles [7,8,20]. One      that is dependent on one or other independent continuants and
salient feature of relative places is that they may move relative       can migrate from one bearer to another through a process of
to one another when their reference objects move relative to one        copying. We can think of generically dependent continuants as
another. Using Donnelly’s [17] example, when a ship moves               complex continuant patterns either of the sort created by authors
relative to the earth, places with the ship as their reference object   or designers or (in the case of DNA sequences) brought into
(e.g. the ship’s hold) move relative to places with the earth as        being through the processes of evolution” [4, p. 179]. Examples
their reference object. In a similar vein, role positions may           include the pdf file on Mary’s laptop and the pdf file that is a
‘conceptually move’ relative to one another when their contexts         copy thereof on John’s laptop. Characteristically, a generically
‘conceptually move’ relative to one another. For instance, when         dependent continuants exists only if it is concretized in some
a human resource department changes its importance with                 counterpart specifically dependent continuant. To take one
respect to its company, personnel director role positions (whose        example, a paragraph of a novel in concretized in each pattern
context is the human resource department) change their                  (quality) of ink on the pages of the printed novel.
relationship with executive role positions (whose context is the
                                                                        One subtype of specifically dependent continuant is a realizable
company).
                                                                        entity (subtypes of which are to be discussed in detail below):
C)   Role Potential                                                     “A specifically dependent continuant entity that has at least one
                                                                        independent continuant as its bearer, and whose instances can be
Yet another interpretation of Mary’s studentness builds upon the        realized (manifested, actualized, executed) in associated
ability of Mary to do something role-associated (which is               processes of specific correlated types in which the bearer
sometimes informally called ‘circumstantial possibility’). Since        participates” [4, p. 183]. Examples include the role of being a
she is a UB student, Mary can do many things (e.g., getting a           doctor, the disposition of a fragile glass to break, and the
student discount). She is able to acquire a degree from UB,             function of a hammer to hit nails.
whereas non-UB students are not. Mary’s studentness would be
explainable in terms of the potential that she can have in bearing      A)   Role Specification as a BFO-generically Dependent
a student role.                                                              Continuant

A role potential designates a role that is thought of as a sort of      A role specification would be most reasonably classified as a
circumstantial ability and role-bearing is translated as having a       generically dependent continuant. For one thing, a specification
role potential. It is important to remark that a role-bearer has        is plausibly taken to be a generically dependent continuant.
only to possess the role-related ability instead of demonstrating       Duncan [14] analyzes Turner’s [13] conception of specification
it actually. To remain a UB student (i.e., to bear a UB-student         on the basis of BFO and contends that it is a kind of information.
role), Mary does not need to use any student discount; it is only       To our eyes, information is naturally seen as a generically
necessary that she be able to do it.                                    dependent continuant because it obeys the ‘rule of migration’.
A role potential may be easiest to understand in the role triad         For another, an ontological theory of role that endorses
because it is intuitively grasped as a special kind of ability and      explicitly a role specification can be construed in the BFO
avoids complications added by analogies with the complex                fashion as a commitment to the view that a role is a generically
notions such as a specification (in the case of a role                  dependent continuant. Masolo et al. [8] propose a general
specification) and a relative place (in the case of a role position).   framework for social roles in compliance with an upper ontology
In contrast, a role potential should be treated with the utmost         the Descriptive Ontology for Linguistic and Cognitive
caution because it could be otherwise conflated with other              Engineering (DOLCE) [21]. At the nub of their argument is that
apparently similar but different entities, viz. dispositions and        social roles are fundamentally characterized by the DOLCE
functions (see Section IV for details on this point).                   entity of description. As Toyoshima [12] argues, they take a
                                                                        specification approach to role and a DOLCE-description could
                                                                        be well conceived as a generically dependent continuant that is
III. Roles and Their Siblings in BFO
                                                                        connected to agents’ intentionality.

In this section we delineate into which BFO category falls each         Examples (1)-(3) are explicable in terms of a role specification
of the role triad (a role specification, a role position, and a role    as a generically dependent continuant (see [5, p. 101] concerning
performance) and other ontological accounts of the term ‘role’.         Examples (2)-(3)). In Example (1), a pilot role of a passenger
We also illustrate them with the examples (1)-(8) listed in             means a generically dependent continuant whose bearers are
Section I. Note that this section draws partially upon Toyoshima        passengers, or especially those who know well about the
[12] (especially its Section 4.3).                                      operation of the plane. In Example (2), the role of director of the
                                                                        institute depends generically on people (including Jane) with
some qualifications (e.g., age and career). In Example (3), the         D)   ‘Role’ as a BFO-disposition
particular role in the play can migrate among actors (such as
Joe), e.g., with a certain level of acting proficiency.                 We have above pondered three facets of role and their BFO
                                                                        categories, but the term ‘role’ may be too polysemous to be
B)   Role Position as a BFO-site                                        understood in terms of the ontological notion of role alone.
                                                                        Consider Example (7): ‘the role of a magnet to attract iron
The BFO categorization of a role position would be more                 objects’. None of the role triad captures the meaning of the term
controversial than that of a role specification owing to the still      ‘role’ of this example. In particular, a magnet attracts iron
unclear character of the former. A role position is however             objects permanently and essentially rather than temporally and
arguably most persuasively regarded as a site. A site is “a three-      accidentally. We submit that, contrary to its linguistic surface,
dimensional immaterial entity that either (1) is (partially or          the term ‘role’ thereof refers to the BFO entity of disposition. A
wholly) bounded by a material entity or (2) is a three-                 disposition is: “A realizable entity (a power, potential, or
dimensional immaterial part of an entity satisfying (1)” [4, p.         tendency) that exists because of certain features of the physical
112], where a material entity is an “independent continuant that        makeup [material basis] of the independent continuant that is its
has some portion of matter as part, is spatially extended in three      bearer” [4, p. 178, with our supplementary explanation]. A
dimensions, and that continues to exist through some interval of        classical example of a disposition is fragility: the disposition to
time, however short” [4, p. 180] and an immaterial entity is an         break when pressed with a certain force. More specifically,
“independent continuant that contains no material entities as           fragility of a glass is the disposition of the glass (bearer) to break
parts” [ibid.]. Examples of sites include a rabbit hole, Mary’s         (realization) that depends on a particular physical molecule
nasal cavity, and a kangaroo pouch.                                     structure (material basis) of the glass.
A site-based perspective on a role position has its advantages          In BFO, dispositions sharply contrast with roles in terms of
and disadvantages. A site obviously represents the BFO way of           ‘groundedness’. Dispositions are internally grounded: if a
incorporating a relative place (see e.g., [22,23]), and it would be     disposition ceases to exist, then its bearer is physically changed.
straightforward to label a role position as a site. On the other        Roles are externally grounded in the sense that this is not the
hand, a role position would be considerably different from a site       case; see the item (2) of the BFO definition of role. The BFO
in the sense of not being explicitly bound or demarcated in             grounding differentiation between dispositions and roles would
relation to material entities. In the Mary-student example, it          mesh with our temporal and modal one between artifactness and
might be possible to think that Mary’s role position is the kind        role. When a bearer (whether natural or artifactual) of a
of site that is formed with respect to physical buildings               disposition fails to have the disposition, the bearer may
possessed by UB, but only with a worry over a somewhat                  sometimes (if not always) lose its essence. An aircraft would be
arbitrary reification of role positions. It is nonetheless equally      no longer an aircraft when it loses a disposition to fly, for
true that there is no other promising BFO-categorical candidate         example. In that case, the disposition of a bearer determines the
for a role position. Finally, Example (4) can be well explained         essence of the bearer (or at least serves to do so). In Example
from the viewpoint of a role position as a site: the role of the        (7), a magnet has a disposition to attract iron objects and this
damaged stellar neuron refers to a site that is identified relative     disposition embodies the essence of the magnet. However, a
to the brain (context) and it is now ‘occupied’ by the pyramidal        bearer of a role is always the same physically even when the
neuron.                                                                 bearer loses that role, and a role is a mere accidental feature of
                                                                        its bearer. Mary remains physically unchanged when she is
C)   Role Potential as a BFO-role                                       admitted to UB, and her studentness is (ontologically) irrelevant
It is not hard to see that a role potential accords well with the       to her essential nature (which may be extremely difficult to
BFO category of role: “A realizable entity that (1) exists because      define explicitly, though).
the bearer is in some special physical, social, or institutional set    E)    ‘Role’ as a BFO-function
of circumstances in which the bearer does not have to be, and (2)
is not such that, if this realizable entity ceases to exist, then the   The dispositional clarification of the term ‘role’ extends to the
physical make-up of the bearer is thereby changed. A role is thus       BFO category of function because BFO, or precisely the latest
always optional” [4, p. 184]. Given the BFO conception of role,         version of BFO (BFO 2.0) conceives function dispositionally
for instance, Mary is a UB student in virtue of her student role        [24] (see [25,26] for criticism): “A function is a special kind of
that can be realized in, e.g., a process of her using a student         disposition. It is a realizable entity whose realization is an end-
discount. This would mean that a BFO-role is closely akin to a          directed activity of its bearer that occurs because this bearer is
circumstantial ability, which underlies the idea of a role              (a) of a specific kind and (b) in the kind or kinds of contexts that
potential.                                                              it is made or selected for. Thus a function is a disposition that
As said above, the potential view of role would require                 exists in virtue of the bearer’s physical make-up, and this
elucidation of roles and other comparable entities such as              physical make-up is something the bearer possesses because of
dispositions and functions. This issue is to be addressed in            how it came into being --- either through natural selection (in the
Section IV. In addition, it will be also discussed there the            case of biological entities) or through intentional design (in the
question of why BFO takes a potential-centered approach to              case of artifacts)” [4, pp. 102-103].
role. Examples (5)-(6) are interpretable in terms of a role             To illustrate this, consider Example (8): ‘the role of the heart to
performance as a role. In Example (5), Jim’s nurse role is a role       pump blood’. First of all, the heart has a disposition to pump
that can be realized in processes of his taking care of sick or         blood: it depends on a certain organic structure of the heart and
injured people. In Example (6), the stone in question bears a role      the heart would undergo physical change when it loses this
that can be realized in a process of boundary demarcation.              disposition. Analyzed more meticulously, the disposition of the
heart to pump blood is a function of the heart because it has           Aristotelian definition [32] where a term can be defined by dint
emerged through evolutionary processes of the organism. To              of a genus (as a species with a differentia). The identity of a
take another example, consider the phrase ‘the role of an aircraft      generically dependent continuant is a highly debatable topic (see
to carry goods or passengers’. In ontological parlance, an aircraft     e.g., [6,33,34]); and so is a site (but see [17] for some thoughts).
has a function (but not a role) to carry good or passengers             We can safely say however that both of the definitions of a role
because the aircraft has been designed and produced to do so. A         specification and a role position should comprise the BFO term
relationship between role and function is however further               ‘role’ since it is so paramount as to ground all other role-related
complicated by the issue of ‘use function’ to be addressed in           notions in BFO; and that a role specification needs to be
Section IV.                                                             constrained at least by its bearer and its concretization, and a
                                                                        role position at least by which material entity bounds or
                                                                        demarcates it.
IV. Discussion
                                                                        Taking all this into consideration, first of all, it is reasonable to
                                                                        think that a role specification has as its bearer a bearer of a role
A)   The Role Triad in BFO and Ontological Realism
                                                                        and it is also concretized in the role of the bearer. Suppose for
Although we have identified the five BFO meanings of the term           instance that, in Example (2), Bob was the sixth director of the
‘role’, questions remain about a detailed description of the BFO        institute. In this scenario, Jane’s director role differs from Bob’s,
conception of the role triad. Here three of them will be brought        but they both concretize the same role specification to the effect
up for discussion. First, why does BFO put a premium on a role          that, e.g., a director of the institute is in charge of activities of
potential, as is supported by the finding that it is classified as a    the members of the institute. Next, informally speaking, a role
role in BFO? Toyoshima [12] holds that there is a strong                position would be plausibly relativized to the context in which a
correlation between role choices of upper ontologies and their          certain independent continuant can have some role. It could be
meta-ontological choices [27]: roughly, choices that are                further added that a role position can be occupied by the role-
fundamental enough to determine ontological choices [21],               bearer under discussion. In Example (4), a role position exists in
namely choices as to whether and how a certain ontological              relation with the brain and it was at first occupied by a healthy
category or relation is adopted. The DOLCE theory of role               stellar neuron, but later it is by the pyramidal neuron. Finally,
focuses on a role specification, for instance, because DOLCE            preliminary definitions of a role specification and a role position
aims to represent categories with a clear cognitive bias that are       are provided as follows:
associated with e.g., human cognition and socio-cultural artifacts         •    BFO-role specification =def. a generically dependent
(which is a DOLCE meta-ontological choice), and a role                          continuant (i) whose bearer has a role and (ii) that is
specification is arguably the most cognitive and/or linguistic                  concretized in the role of the bearer.
way of understanding roles in the sense of emphasizing their
intentional aspect.                                                        •     BFO-role position =def. a site that (i) exists relative to
                                                                                 the special physical, social, or institutional set of
Toyoshima [12] attributes the BFO role choice of a role                          circumstances in virtue of which an independent
potential to the BFO meta-ontological adoption of ontological                    continuant can have a role and (ii) can be occupied by
realism [28] (see [29,30] for criticism): “The realist                           the role-bearer.
methodology is based on the idea that the most effective way to
                                                                        It should be noted that the item (i) of the definition of a role
ensure mutual consistency of ontologies over time and to ensure
                                                                        position depends on part of the BFO existing definition of a role;
that ontologies are maintained in such a way as to keep pace            and that a role position does not always need to be occupied by
with advances in empirical research is to view ontologies as            some role-bearer and it can be occupied by different role-bearers
representations of the reality that is described by science. This is    at different times. We intend to leave room for the flexibility of
the fundamental principle of ontological realism” [28, p. 139]. It      role positions so that they could help to solve some existing
is a rather complicated matter to assess exactly what ontological       problems with a BFO-role (see below for details).
realism entails (see e.g., [31]), but one plausible corollary of this
policy would be that BFO-based ontologies should maximize               Third and lastly, why does BFO specify only the role-having
symbiosis with empirically scientific inquiry, which would              relation (has_role) but not the role-playing one [3, p. 58]? As is
imply in turn that the BFO notion of role should be consistent          indicated by Examples (1), (3), and (4), talk of role-playing is
                                                                        quite commonplace in our everyday life. It is however
with scientific activities. This results reasonably in the BFO
                                                                        contentious whether and how the phrase ‘plays a role’ should be
choice of a role potential because scientists typically focus on        taken with ontological seriousness (see e.g., [35]). One tenable
the structure and behavior of the natural world. To investigate         idea would be that role-playing conveys the level of achievement
the human mind, for instance, contemporary cognitive scientists         of role-related goals. Mary’s behavior is evaluable by a criterion
and psychologists tend to highlight the importance of people’s          (e.g., obtained credits) for being a student, for instance. Different
behaviors such as their facial expressions and actions. Taken           role choices would yield different understandings of role-playing,
with a scientific attitude, roles (e.g., Mary’s student role) would     namely as meeting a role specification, as occupying a role
be preferably ontologized in terms of externally observable             position, or as having a role potential. Characteristic of the BFO
performances of role-bearers (e.g., Mary’s using a student              construal of role is to reduce the alleged role-playing to
discount).                                                              realization. Mary’s student actions are explicable in terms of
                                                                        realizations of her student role. Accordingly, BFO only needs the
Second, how can a role specification and a role position be             standard property-having relation (one subtype of which is the
described or defined given the BFO performance-oriented view            has_role relation), instead of a new primitive role-playing one.
of role? This amounts to the problem of what kind of generically
dependent continuant (resp. site) is a role specification (resp. a
role position), assuming the ontology-design method of the
B)   Roles, Dispositions, and Functions                                  C)    Roles in Biomedical Ontologies

There is a broad consensus on the high utility for ontologizing a        As was alluded to in Section I, roles are crucial for biomedical
wide array of entities that is possessed by realizable entities,         ontologies, partly because of the widespread usage of the term
ranging from the BFO subtypes of realizables [36] (i.e.,                 ‘role’ in the biomedical literature, partly because of a growing
dispositions, functions, and roles) to other kinds of realizables        importance of social roles in ontologies of healthcare systems.
(e.g., tendencies [37]). It is nevertheless a highly controversial       As for the former, we have explicated the term ‘role’ by
subject how BFO-realizables are to be individuated. It would be          leveraging some existing BFO categories. This will help
indeed valuable to elaborate on a comparatively revisionary              biologists and medical specialists to understand correctly the
classification of BFO-realizables (see e.g., [25]). To simplify the      term ‘role’ and represent accurately its meaning on a case-by-
matter, however, we will confine ourselves to two topics                 case basis when they build and/or ameliorate OBO ontologies.
regarding the interrelationships between roles and other two
                                                                         We have also shown that the BFO potential-centered conception
realizable entities while retaining the present, BFO 2.0
                                                                         of role is well-suitable for scientific ontologies in general. This
characterization of them.
                                                                         is all the more the case with biomedical ontologies for several
First, a cloud of suspicion may hang over the ‘grounding                 reasons. First, ontological realism is currently one of the most
distinction’ between roles and dispositions. Guarino [38, p. 17]         prevailing approaches to biomedical ontologies [40]. Second,
asserts, for example: “I think that, especially for social roles, the    BFO-roles are relatively understandable for biomedical experts
corresponding attitudes/commitments/dispositions are not                 because they are closely akin to dispositions, which are central
independent from the physical make-up of their bearer. For               to biomedicine [37] and serve as a useful conceptual tool for an
instance, the commitment to realize a student role of course             ontological analysis of the explanatory practice in biomedicine
requires some changes in the brain’s “make-up” of its bearer. I          from both theoretical [41] and practical [42,43,44] points of
would say that, in general, active role-properties (being the lover      view. Third, it has been pointed out that “many so-called
of Mary) presuppose some (non-essential) change in the physical          functions in biomedical ontologies are, strictly speaking, roles”
make-up of their role bearers, while this is not required for            [25, p. 11].
passive roles (being loved by John).” Paraphrased using the
                                                                         As for the latter, our work will have implications for the
Mary-student example, the core of his argument is that Mary’s
                                                                         construction of social ontologies in the biomedical domain. For
student role should not be a BFO-role (an externally grounded
                                                                         one thing, there is general agreement among researchers in
realizable entity) because there must be some physical change
                                                                         social ontologies aligned with BFO that deontic entities (e.g.,
involved in Mary’s entering UB.
                                                                         claims, obligations, and rights) are most appropriately classified
Although it may be a misinterpretation of a BFO-role, Guarino’s          as generically dependent continuants that are concretized in
criticism would help to elucidate the difference between roles           (social) roles, regardless of whether they are, more concretely,
and dispositions. Quite important is the observation that the            socio-legal generically dependent continuants [45] or directive
change (including emergence and disappearance) of roles are              information entities [46] or others. Deontic entities as construed
frequently concurrent with that of dispositions. To see this point,      this way can be viewed as a subtype of role specifications; and
let us stipulate that Mary became more diligent after graduation         in this regard, we might have discussed in some way a
from UB. It would appear that Mary’s assiduity was caused by             theoretical foundation for deontic entities in social ontology.
her neural transformation, which was in turn by her student role.
                                                                         For another, it is nowadays fairly popular to model organizations
Actually, however, Mary’s diligence should be ascribed to the
                                                                         (totally or partially) upon interrelations among roles in various
fact that Mary’s disposition to work hard was strengthened by
                                                                         disciplines, including multiagent systems [47,48] and
realizations (e.g., taking classes at UB) of her student role which
                                                                         foundational ontology research [49,50,51]. It is sometimes
she no longer bears after graduation. On the other hand, Mary’s
                                                                         claimed however that the BFO conception of role fits badly with
disposition to go to UB may have been greatly weakened when
                                                                         this approach because it faces what may be called the ‘problem
she lost her UB-student role.
                                                                         of non-transferability’ [46] or especially the ‘problem of vacant
Second, we have seen the cases in which the term ‘role’ refers to        (empty) role’. Being postulated to be represented by a
a disposition or a function. One may wonder about their                  configuration of roles, an organization should remain the same
opposite: the term ‘disposition’ or ‘function’ means a role when         even when there exists a ‘vacant role’: a role to be beard by
coming under scrutiny. To the best of our knowledge, the term            nobody. Recall an extensive story of Example (2) in Section IV-
‘disposition’ rarely, if ever, refers to a role; whereas greater care    A: the structure of the institute has not changed itself since Bob
may be needed to ensure that the term ‘function’ does not                resigned as the sixth director until Jane is newly elected as the
designate a role. To illustrate the latter, consider the issue of ‘use   seventh director. BFO-roles would nonetheless seem to embrace
function’: roughly, the kind of functions that agents attribute to       the discrepancy between the real structure of an organization and
objects in actually using them for their use purpose (see e.g.,          its ‘role structure’ because they have to depend specifically on
[39] for more details). If Mary uses a screw driver to open her          individual agents (such as Bob and Jane) and they are thus non-
paint cans, for instance, it has the use function to open paint cans     transferable. The issue of vacant role is still unresolved, but one
[25]. In spite of an ongoing discussion about BFO-functions, the         possible answer to this question may be to ground an
disputants generally acknowledge that use functions should be            organizational structure upon a constellation of role positions
categorized as roles because they are ‘accidental functions’: they       (rather than roles) of the organization because role positions
have nothing to do with the essence of their bearers [24,25].            thereof, by definition, exist even in the case of vacant roles,
                                                                         insofar as does the organization. Our complete solution to the
                                                                         general problem of non-transferability will require not only
                                                                         clearer delineation of the idea of a role position but also careful
ontological consideration of the identity of organizations (see        Guarino [38, p. 14] states that it “reflects a very peculiar
e.g., [52]).                                                           understanding of the role notion which, although useful, would
                                                                       require a broader framework”. We hope that our argument over
                                                                       BFO-roles and their sibling entities will dispel this kind of worry.
V. Conclusion

To summarize, we examined within the BFO framework the                 Address for correspondence
meanings of the term ‘role’. We also discussed the BFO
potential-oriented conception of role as an externally grounded        Fumiaki Toyoshima. E-mail: toyo.fumming@gmail.com;
realizable entity with a focus on its connections with ontological     fumiakit@buffalo.edu.
realism, dispositions, and functions as well as its usefulness for
an ontological modeling in the biomedical field. We ended up           References
with the following BFO-based disambiguation of the term ‘role’
in the aforementioned examples (1)-(8):
                                                                       1.  J. Fan, K. Barker, B. Porter and P. Clark. Representing
   1.    A passenger plays the role of a pilot on a commercial             Roles and Purpose. In Proceedings of the 1st International
         plane in an emergency.                                            Conference on Knowledge Capture (K-CAP’01), Victoria,
                                                                           British Columbia, Canada, October 22-23, 2001, ACM
   •    Generically dependent continuant (role specification)              Press, 38-43.
   2.    Jane’s being the seventh person to fill the role of           2. F. Steimann. On the representation of roles in object-
         director of this institute                                        oriented and conceptual modelling. Data & Knowledge
                                                                           Engineering, 35(1), 83-106, 2000.
   •    Generically dependent continuant (role specification)          3. B. Smith et al. Basic Formal Ontology 2.0 - Specification
   3.    Joe’s being the third person to play a particular role in a       and User’s Guide, 2015. Available online at:
         play                                                              https://github.com/BFO-ontology/BFO (Last accessed on
                                                                           July 14, 2019).
   •    Generically dependent continuant (role specification)          4. R. Arp, B. Smith and A. D. Spear. Building Ontologies
   4.    A pyramidal neuron plays the role occupied by a                   with Basic Formal Ontology. Cambridge, MA: The MIT
         damaged stellar neuron in the brain. Site (role position)         Press, 2015.
                                                                       5. A. Hicks, J. Hanna, D. Welch, M. Brochhausen and W. R.
   •    Site (role position)                                               Hogan. The ontology of medically related social entities:
                                                                           recent developments. Journal of Biomedical Semantics, 7:
   5.    Jim has the role of a nurse.
                                                                           47, 2016.
   •    Site (role position)                                           6. J.-F. Ethier, A. Barton and R. Taseen. An ontological anal-
                                                                           ysis of drug prescriptions. Applied Ontology, 13(4), 273-
   6.    the role of a stone in marking a boundary                         294, 2018.
   •    Role (role potential; an externally grounded realizable        7. G. Boella, L. van der Torre and H. Verhagen. Roles, an
        entity)                                                            interdisciplinary perspective. Applied Ontology, 2(2), 81-
                                                                           88, 2007.
   7.    the role of a magnet to attract iron objects                  8. C. Masolo, L. Vieu, E. Bottazzi, C. Catenacci, R. Ferrario,
   •    Disposition (an internally grounded realizable entity)             A. Gangemi and N. Guarino. Social Roles and Their De-
                                                                           scriptions. In D. Dubois, C. Welty and M. A. Williams
   8.    the role of the heart to pump blood                               (Eds.), Principles of Knowledge Representation and Rea-
   •    Function (a subtype of disposition)                                soning: Proceedings of the 9th International Conference
                                                                           (KR 2004), Whistler British Columbia, Canada, June 2-5,
                                                                           2004, 267-277.
In the future we will be able to proceed along two main                9. V. Genovese. Towards a General Framework for Model-
directions of research. On the theoretical side, further                   ling Roles. In G. Boella, L. van der Torre and H. Verhagen
development is warranted of the BFO characterization of a role             (Eds.), Normative Multiagent Systems, number 07122 in
specification and a role position, which will require in turn a            Dagstuhl Seminar Proceedings. Internationales Be-
deeper understanding of a generically dependent continuant and a           gegnungs- und Forschungszentrum für Informatik (IBFI),
site. Besides, further clarification should be given to complex            Schloss Dagstuhl, Germany, 2007.
relationships between roles, dispositions, and function. On the        10. F. Loebe. Abstract vs. social roles: Towards a general theo-
practical side, the utility of the BFO specification hitherto of the       retical account of roles. Applied Ontology, 2(2), 127-158,
term ‘role’ needs to be verified through its application to the            2007.
building and enhancement of biomedical ontologies, e.g., of            11. B. Smith et al. The OBO Foundry: coordinated evolution of
healthcare systems [5,6]. In addition, since ontological realism
                                                                           ontologies to support biomedical data integration. Nature
prescribes that ontologies should represent, above all, universals
                                                                           Biotechnology, 25, 1251-1255, 2007.
[28], this necessitates the extension of our work on the role triad
to the sphere of universals and their formal representation            12. F. Toyoshima. Three Facets of Roles in Foundational On-
specified in e.g., Web Ontology Language (OWL) [53]. Finally,              tologies. In L. Jansen, D. P. Radicioni and D. Gromann
among BFO-realizables, roles have been less carefully                      (Eds.), Proceedings of the Joint Ontology Workshops 2018
investigated than dispositions and functions. This may raise               (JOWO 2018), Cape Town, South Africa, September 17-
doubts about the BFO characterization of role. For instance,               18, 2018, CEUR Workshop Proceedings, vol. 2205.
13. R. Turner. Specification. Minds & Machines, 21(2), 135-             ence on Formal Ontology in Information Systems (FOIS
    152, 2011.                                                          2018), Cape Town, South Africa, September 17-21, 2018,
14. W. D. Duncan. Ontological distinctions between hardware             Amsterdam: IOS Press, 1-9. doi: 10.3233/978-1-61499-
    and software. Applied Ontology, 12(1), 5-32, 2017.                  910-2-1.
15. L. Vieu, S. Borgo and C. Masolo. Artefacts and Roles:         32.   B. Smith. New Desiderata for Biomedical Ontologies. In
    Modelling Strategies in a Multiplicative Ontology. In C.            K. Munn and B. Smith (Eds.), Applied Ontology: An Intro-
    Eschenbach and M. Grüninger (Eds.), Proceedings of the              duction, Frankfurt: Ontos Verlag, 2008, 84-107.
    5th International Conference (FOIS 2008), Saarbrücken,        33.   B. Smith and W. Ceusters. Aboutness: Towards Founda-
    Germany, October 31 - November 3, 2008, Amsterdam:                  tions for the Information Artifact Ontology. In F. M. Couto
    IOS Press, 121-134.                                                 and J. Hastings (Eds.), Proceedings of the 6th International
16. K. Fine. Essence and Modality. Philosophical Perspec-               Conference on Biomedical Ontology (ICBO 2015), Lisbon,
    tives, 8, 1-16, 1994.                                               Portugal, July 27-30, 2015, CEUR Workshop Proceedings,
17. M. Donnelly. Relative Places. Applied Ontology, 1(1), 55-           vol. 1515.
    75, 2005.                                                     34.   W. R. Hogan and W. Ceusters. Diagnosis, misdiagnosis,
18. R. Mizoguchi, E. Sunagawa, K. Kozaki and Y. Kitamura.               lucky guess, hearsay, and more: an ontological analysis.
    A Model of Roles within an Ontology Development Tool:               Journal of Biomedical Semantics, 7:54, 2016. doi:
    Hozo. Applied Ontology, 2(2), 159-179, 2007.                        0.1186/s13326-016-0098-5.
19. B. Smith. Beyond Concepts: Ontology as Reality Repre-         35.   R. Mizoguchi, A. Galton, Y. Kitamura and K. Kozaki.
    sentation. In A. C. Varzi and L. Vieu (Eds.), Proceedings           Families of roles: A new theory of occurrent-dependent
    of the 4th International Conference on Formal Ontology in           roles. Applied Ontology, 10(3-4), 367-399, 2015.
    Information Systems (FOIS 2004), Torino, Italy, November      36.   R. Arp and B. Smith. Function, Role, and Disposition in
    4-6, 2004, Amsterdam: IOS Press, 31-42.                             Basic Formal Ontology. In Proceedings of the Bio-
20. J. F. Sowa. Knowledge Representation: Logical, Philo-               Ontologies Workshop, Intelligent Systems for Molecular
    sophical and Computational Foundations. USA:                        Biology (ISMB 2008), Toronto, Canada, July 19-23, 2008,
    Brooks/Cole, 2000.                                                  45-48.
21. S. Borgo and C. Masolo. Ontological Foundations of            37.   L. Jansen. Tendencies and other Realizables in Medical
    DOLCE. In R. Poli, M. Healy and A. Kameas (Eds.), Theo-             Information Sciences. The Monist 90, 534-554, 2007.
    ry and Applications of Ontology: Computer Applications,       38.   N. Guarino. BFO and DOLCE: So Far, So Close.... Cosmos
    Netherlands: Springer, 2010, 279-295.                               + Taxis, 4(4), 10-18, 2016.
22. B. Smith and A. Varzi. The Niche, Noûs, 33:2, 198-222,        39.   R. Mizoguchi, Y. Kitamura and S. Borgo. A unifying defi-
    1999.                                                               nition for artifact and biological functions. Applied Ontolo-
23. B. Smith and A. Varzi. Surrounding Space: The Ontology              gy, 11(2), 129-154, 2016.
    of Organism-Environment Relations. Theory in Bioscienc-       40.   W. Ceusters and B. Smith. A Realism-Based Approach to
    es, 121, 139-162, 2002.                                             the Evolution of Biomedical Ontologies. In Proceedings of
24. A. D. Spear, W, Ceusters and B. Smith. Functions in Basic           the AMIA Symposium, Washington, DC, USA, November
    Formal Ontology. Applied Ontology, 11(2), 103-128, 2016.            11-15, 2006, AMIA, vol. 2006, 121-125.
25. J. Röhl and L. Jansen. Why functions are not special dispo-   41.   A. Hüttemann and M. I. Kaiser. Potentiality in Biology. In
    sitions: an improved classification of realizables for top-         K. Engelhard and M. Quante (Eds.), Handbook of Potenti-
    level ontologies. Journal of Biomedical Semantics, 5:27,            ality, Netherlands: Springer, 2018, 401-428.
    2014.                                                         42.   R. H. Scheuermann, W. Ceusters and B. Smith. Toward an
26. L. Jansen. Functions, Malfunctioning, and Negative Causa-           Ontological Treatment of Disease and Diagnosis. Summit
    tion. In A. Christian, D. Hommen, N. Retzlaff and G.                on Translational Bioinformatics, 116-120, 2009.
    Schurz (Eds.), Philosophy of Science. European Studies in     43.   A. Goldfain, B. Smith and L. G. Cowell. Dispositions and
    Philosophy of Science, vol. 9. Springer, Cham, 117-135,             the Infectious Disease Ontology. In A. Galton and R. Mi-
    2018.                                                               zoguchi (Eds.), Proceedings of the 6th International Con-
27. S. de Cesare, F. Gailly, G. Guizzardi, M. Lycett, C. Par-           ference of Formal Ontology in Information Systems (FOIS
    tridge and O. Pastor. 4th International Workshop on Ontol-          2010), Toronto, Canada, May 11-14, 2010, Amsterdam:
    ogies and Conceptual Modeling (Onto.Com). In O. Kutz                IOS Press, 400-413.
    and S. de Cesare (Eds.), Proceedings of the 2nd Joint On-     44.   A. Barton, O. Grenier and J.-F. Ethier. The Identity and
    tology Workshops (JOWO 2016), Annecy, France, July 6-9,             Mereology of Pathological Dispositions. In L. Cooper and
    2016. CEUR Workshop Proceedings, vol. 1660.                         P. Jaiswal (Eds.), Proceedings of the 9th International
28. B. Smith and W. Ceusters. Ontological realism: A method-            Conference on Biological Ontology (ICBO 2018), Corval-
    ology for coordinated evolution of scientific ontologies.           lis, Oregon, USA, August 7-10, 2018, CEUR Workshop
    Applied Ontology, 5(3-4), 139-188, 2010.                            Proceedings, vol. 2285.
29. G. H. Merrill. Ontological realism: Methodology or misdi-     45.   M. Brochhausen, M. B. Almeida and L. Slaughter. To-
    rection? Applied Ontology, 5(2), 79-108, 2010.                      wards a formal representation of document acts and result-
30. G. H. Merrill. Realism and reference ontologies: Consider-          ing legal entities. In C. Svennerlind, J. Almäng and R.
    ations, reflections and problems. Applied Ontology, 5(3-4),         Ingthorsson (Eds.), Johanssonian Investigations: Essays in
    189-221, 2010.                                                      Honour of Ingvar Johansson on His Seventieth Birthday,
31. S. Borgo and P. Hitzler. Some Open Issues After Twenty              Walter de Gruyter, 2013, 120-139.
    Years of Formal Ontology. In S. Borgo, P. Hitzler and O.      46.   B. Donohue. Toward a BFO-Based Deontic Ontology. In
    Kutz. (Eds.), Proceedings of the 10th International Confer-         M. Horridge, P. Lord and J. D. Warrender (Eds.), Proceed-
      ings of the 8th International Conference on Biomedical
      Ontology (ICBO 2017), Newcastle upon Tyne, UK, Sep-
      tember 13-15, 2017, CEUR Workshop Proceedings, vol.
      2137.
47.   J. J. Odell, H. V. D. Parunak and M. Fleischer. Modeling
      agent organizations using roles. Software and System Mod-
      eling, 2, 76-81, 2003. doi: 10.1007/s10270-003-0017-y.
48.   O. Pacheco and J. Carmo. A Role Based Model of Norma-
      tive Specification of Organized Collective Agency and
      Agents Interaction. Autonomous Agents and Multiagent
      Systems, 6, 145-184, 2003.
49.   M. S. Fox, M. Barbuceanu, M. Gruninger and J. Lin. An
      organisation ontology for enterprise modelling. In M. Pri-
      etula, K. Carley and L. Gasser (Eds.), Simulating Organi-
      zations: Computational Models of Institutions and Groups,
      Menlo Park, CA: AAAI/MIT Press, 1998, 131-152.
50.   G. Boella and L. van der Torre. A Foundational Ontology
      of Organizations and Roles. In M. Baldoni and U. Endriss
      (Eds.), Declarative Agent Languages and Technologies IV
      (DALT 2006), Lecture Notes in Computer Science, vol
      4327, Berlin, Heidelberg: Springer-Verlag, 2006, 78-88.
51.   E. Bottazzi and R. Ferrario. Preliminaries to a DOLCE
      Ontology of Organizations. International Journal of Busi-
      ness Process Integration and Management (Special Issue
      on Vocabularies, Ontologies and Business Rules for Enter-
      prise Modeling), 4(4), 225-238, 2009.
52.   R. Ferrario, C. Masolo and D. Porello. Organisations and
      Variable Embodiments. In S. Borgo, P. Hitzler and O.
      Kutz. (Eds.), Proceedings of the 10th International Confer-
      ence on Formal Ontology in Information Systems (FOIS
      2018), Cape Town, South Africa, September 17-21, 2018,
      Amsterdam: IOS Press, 127-140. doi: 10.3233/978-1-
      61499-910-2-127.
53.   I. Horrocks, P.-F. Patel-Schneider, D. L. McGuinness and
      C. A. Welty. OWL: a Description-Logic-Based Ontology
      Language for the Semantic Web. In F. Baader, D. Calva-
      nese, D. L. McGuinness, D. Nardi and P. F. Patel-
      Schneider (Eds.), The Description Logic Handbook: Theo-
      ry, Implementation and Applications (Second Edition),
      Cambridge: Cambridge University Press, 2007, 458-486.