Preface ICBO 2019: 10th International Conference on Biomedical Ontology July 30 - August 2, 2019, Buffalo, NY, USA (ICBO 2019 website) The 10th International Conference on Biomedical Ontology (ICBO 2019), was held at the Jacobs School of Medicine and Biomedical Sciences of the University at Buffalo, in Buffalo, NY, USA. It was the 10-year anniversary of the ICBO series, and the return of the conference to Buffalo after the first two ICBO conferences were held in Buffalo in 2009 and 2011. ICBO 2019 was well attended, with 115 registered attendees and additional walk-ins from the local academic community. The program included excellent keynote talks by Barry Smith, “International Standard Ontology,” and Bjoern Peters, “Putting principles into practice: OBO ontologies and applications in immunology,” as well as 23 oral presentations, 26 posters, and one software presentation. There were 53 papers and abstracts submitted for peer-review to ICBO 2019. Each submission was reviewed by three members chosen from the Program Committee. Of these submissions, 43 were accepted for this volume: 19 full papers, 23 poster abstracts, and 1 software demonstration extended abstract. We thank our program committee for their thoughtful reviews. There were also three workshops and four tutorials (listed below) held in conjunction with the main ICBO 2019 meeting. Organizing Committee of ICBO 2019 Alexander D. Diehl, Ph.D. University at Buffalo William D. Duncan, Ph.D. University at Buffalo (now at Lawrence Berkeley National Laboratory) Peter L. Elkin, M.D. University at Buffalo Werner Ceusters, M.D. University at Buffalo Marge Elkin ICBO Series Founder and Advisor to Organizing Committee Barry Smith, Ph.D. University at Buffalo ICBO 2019 Proceedings Editors Alexander D. Diehl, Ph.D. University at Buffalo William D. Duncan, Ph.D. University at Buffalo (now at Lawrence Berkeley National Laboratory) Gloria Sanso University at Buffalo Keynote Speakers Barry Smith University at Buffalo Bjoern Peters La Jolla Institute for Immunology Copyright © 2021 for this paper by its author. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0). 1 Program Committee (all affiliations as of 2019) Sivaram Arabandi OntoPro, TX, USA Adrien Barton Université de Sherbrooke, QC, Canada Jonathan P. Bona University of Arkansas, AR, USA Syed Ahmad Chan Bukhari Yale University, CT, USA Werner Ceusters Unversity at Buffalo, NY, USA Alexander D. Diehl University at Buffalo, NY, USA William D. Duncan University at Buffalo, NY, USA Peter L. Elkin University at Buffalo, NY, USA Pierre Grenon Horizon Asset, United Kingdom Yongqun He University of Michigan, MI, USA Amanda Hicks University of Florida, FL, USA William R. Hogan University of Florida, FL, USA Mark Jensen CUBRIC, NY, USA Simon Jupp European Bioinformatics Institute, United Kingdom Jane Lomax SciBite, United Kingdom Phillip Lord Newcastle University, United Kingdom Kody Moodley Maastricht University, Netherlands Christopher J. Mungall Lawrence Berkeley National Laboratory, CA, USA Darren A. Natale Georgetown University, DC, USA Jihad S. Obeid Medical University of South Carolina, SC, USA James A. Overton Knocean, Inc., ON, Canada Zoe May Pendlington European Bioinformatics Institute, United Kingdom Bjoern Peters La Jolla Institute for Immunology, CA, USA Alan Ruttenberg University at Buffalo, NY, USA Lynn M. Schriml University of Maryland School of Medicine, MD, USA Barry Smith University at Buffalo, NY, USA Nicole A. Vasilevsky Oregon Health & Science University, OR, USA Randi Vita La Jolla Institute for Immunology, CA, USA Danielle Welter European Bioinformatics Institute, United Kingdom Jie Zheng University of Pennsylvania, PA, USA Acknowledgements The organizers would like to thank the Department of Biomedical Informatics of the Jacobs School of Medicine and Biomedical Sciences, University at Buffalo for support and organizational help, especially Winanne Conway, Cheryl Kennedy, and Gloria Reed. We thank the Jacobs School of Medicine and Biomedical Sciences and Dean Michael Cain for their support and use of the School for hosting ICBO 2019. We also thank Lauren Haskins of University Event at the University at Buffalo for administering registration for ICBO 2019. We thank the University at Buffalo for its support of ICBO 2019 and research in ontology in general. 2 Workshops associated with ICBO 2019 1) 8th International Workshop on Vaccine and Drug Ontology Studies (VDOS-2019) Organizers: Junguk Hur, University of North Dakata; Oliver He, University of Michigan; Cui Tao, University of Texas Health Science Center at Houston Wednesday, July 31, 2019 Workshop Page 2) The 3rd international Cells in ExperimentaL Life Science Workshop (CELLS-2019) Organizers: Oliver He, University of Michigan; Alexander Diehl, University at Buffalo; Sirarat Sarntivijai, ELIXIR Hub, Wellcome Genome Campus, UK Wednesday, July 31, 2019 Workshop Page 3) First International Workshop on Biomedical Ontologies & Natural Language Processing Organizers: Jonathan P. Bona, University of Arkansas for Medical Sciences; Peter L. Elkin, University at Buffalo; Daniel R. Schlegel, SUNY Oswego Tuesday, July 30, 2019 Workshop Page Tutorials associated with ICBO 2019 1) An Introduction to Referent Tracking Organizers: Werner Ceusters, University at Buffalo; William Hogan, University of Florida Tuesday, July 30, 2019 Description 2) Basic Formal Ontology and Its Applications in Biomedicine Organizers: Barry Smith and Alan Ruttenberg, University at Buffalo Wednesday, July 31, 2019 Description Slides 3) A How-To Guide to Create, Manage, and Release an OBO Ontology Organizers: Nicole Vasilevsky, OHSU; James Overton, Knocean Inc.; Chris Mungall, LBNL; Rebecca Jackson, La Jolla Institute for Allergy and Immunology & University of Maryland Wednesday, July 31, 2019 Description Materials including links to slides 4) Tutorial: Machine learning with ontologies Organizer: Robert Hoehndorf, Computational Bioscience Research Center, King Abdullah University of Science and Technology, Saudi Arabia Tuesday, July 30, 2019 Description – Alexander D. Diehl, Ph.D., for the organizers 3