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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>IXA at eHealth-KD Challenge 2021: Generic Sequence Labelling as Relation Extraction Approach?</article-title>
      </title-group>
      <contrib-group>
        <aff id="aff0">
          <label>0</label>
          <institution>UPV/EHU IXA research group</institution>
          ,
          <addr-line>Bilbao</addr-line>
          ,
          <country country="ES">Spain</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>The eHealth-KD 2021 is the automatic extraction of knowledge challenge from health documents written in Spanish with a small selection of sentences from di erent domains and languages to encourage cross-lingual and transfer learning approaches, we use the pre-trained Language Model (LM), namely XML-RoBERTa-base, to provide a Crosslingual representation of tokens and the ability to transfer learning from general domains. Our group participated in all the proposed scenarios; the main one (F1 0.499), Entity Recognition (ER) (F1 0.653) and Relation Extraction (RE) (F1 0.430). The present system was designed as a pipeline of generic sequence labellers, each of them independently ne-tuned for each subtask. The generic sequence labeller consists of a feed-forward network that learns how to align a sequence of tokens into a sequence of labels regardless of the language and domain. This simple straightforward system ranked in the third position in the main and Entity recognition scenario and widely outperformed the other systems in the relation extraction scenario.</p>
      </abstract>
      <kwd-group>
        <kwd>eHealthKD 2021</kwd>
        <kwd>Knowledge Discovery</kwd>
        <kwd>Natural Language Processing</kwd>
        <kwd>Deep Learning</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>
        eHealthKD series provide nice scenarios to build and evaluate Natural Language
Processing systems on the medical domain. This year eHealthKD2021 [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] includes
a selection of sentences not exclusively from medical texts but from other domains
and di erent languages. In the last years, the amount of medical texts, regardless
of format, has grown exponentially and accordingly, the interest in its processing
for several clinical purposes. In this paper, we propose a system to extract entity
mentions and their semantic relation type occurring in Spanish texts in the
context of the eHealthKD2021 evaluation task. The system was built in two steps.
We rst identify and classify entity mentions in the sentence, and afterwards,
we classify the relation type of identi ed entity pairs. Sentences are encoded
using ne-tuned XLM-RoBERTa [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ], which is a neural language model trained in
multiple languages including Spanish. We transfer the general knowledge using a
pre-trained model of the XLM-RoBERTa-base language model and ne-tuning it
for the tasks of identifying entities and relations. We propose a simple yet robust
model, where each component is trained separately. This strategy, contrary to
joint models, makes learning easier and faster (focusing on one task at a time)
and gives exibility for domain and language adaptation. With this system, we
hypothesize the idea that generic sequence labellers could competitively handle
the relation extraction task while de ning suitable formats to represent the
problems and accurate ways to conditionate LM.
2
      </p>
    </sec>
    <sec id="sec-2">
      <title>State Of The Art</title>
      <p>
        Actual systems focus on retrain LM for span detection and entity detection
[
        <xref ref-type="bibr" rid="ref3 ref4">3, 4</xref>
        ], LM we use for the task is highly related with the result we achieve for
speci c domains [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ], since LMs have appeared we see that performance of
NLP tasks are directly related to the LM we use to represent textual data.
Relation Extraction (RE) approaches faced the rst revolution on [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ] reaching
high-performance systems [8{10] those are mainly based on BERT technologies
and derivatives. In the clinical domain RE [
        <xref ref-type="bibr" rid="ref11 ref12">11, 12</xref>
        ] we can encounter a
highperformance system based on speci c techniques such as novel architectures of
Bi-LSTM cells. SOTA Domain-agnostic approaches [
        <xref ref-type="bibr" rid="ref13 ref14">13, 14</xref>
        ] follow the idea of
improving the LM representation using adaptive techniques for required task
Sequence Labelling (SL) or RE. Cross-Lingual performance [
        <xref ref-type="bibr" rid="ref15">15</xref>
        ] is mainly derived
from the appearance of the BERT model and the cross-lingual features it provides.
SL [
        <xref ref-type="bibr" rid="ref16 ref17">16, 17</xref>
        ] even is an extensively researched eld, is nowadays widely used in
new application elds such as clinical data mining.
3
      </p>
    </sec>
    <sec id="sec-3">
      <title>System Description</title>
      <p>Generic sequence labelling The 2-stage system to extract entity mentions and
their semantic relation type occurring in Spanish texts is based on a pipeline of
ne-tuned generic sequence labellers as described in 1. We use a feed-forward
network (FFN) to compute the probability y~i = F F N (xi) for each token, where
each value in y~i represents the score for a tag in a target tag set. Equation 1
shows how we formalized the the feedforward network.</p>
      <p>F F N (xi) = sof tmax(Wexi + be)
(1)</p>
      <p>We decided to apply a pipeline of sequence labellers to 1) keep the model
as simple as possible and 2) avoiding over- tting of the model, as it could
learn speci c dependencies in training. For the nal prediction, we apply an
argmax function over the label probability distribution obtained for each token.
The sequence labelling is learned minimizing the cross-entropy loss shown in
Equation 2.</p>
      <p>Lt =
1 N</p>
      <p>X yi log y~i
N i=1
(2)</p>
      <p>Where yi is the true label vector for the input token xi, and N is the
number of instances in the training set for the task. As you deduce, the input
le format is composed of two columns, containing xi and yi pairs per line, the
di erent examples are separated by empty lines. Finally, we use the special token
"jump line" to de ne the end of a text.</p>
      <p>Subtask A: Entity recognition The input provided by the organizer as BRAT
stando format (.ann), was split into texts keeping line jumps, then texts were
divided into tokens keeping white spaces. Those tokens were aligned with the
labels following Inside Outside Beginning format (IOB). This format does not
capture overlapped and disjoint entities. The output of the system was converted
again into (.ann) les.</p>
      <p>
        Subtask B: Relation extraction We applied once again the same tokenization
strategy exposed for entity recognition. In this case, as we already have the
entities identi ed in the previous step, we pairwise each possible combination
generating a repeated example per pair, entity markers [
        <xref ref-type="bibr" rid="ref18">18</xref>
        ] are added surrounding
entities to avoid over tting. In this case, we align the entities with the relation
type. The output of the system was transformed into nal (.ann) les.
Training setup We used huggingface transformers [
        <xref ref-type="bibr" rid="ref19">19</xref>
        ] for default training
parameters setup, both systems were trained over respective train set and ne-tunned
with respective dev set, both performed 40 epochs with a batch size of 40
examples, each ne-tune maximized the f1 score described in Conll2005 shared task
[
        <xref ref-type="bibr" rid="ref20">20</xref>
        ]. The best model of 11 / 12 checkpoints out of 1100 / 12000 total steps were
respectively used for entity recognition / relation extraction. Both models were
calculated in 30 minutes each using a single NVIDIA Titan V.
4
      </p>
    </sec>
    <sec id="sec-4">
      <title>Results</title>
      <p>
        In the following Table 1 we summarize the results in the three di erent scenarios
over the o cial Test set, the best results for each metric are highlighted with
bold characters. The system gets competitive remarks in whole scenarios winning
the third one (Relation extraction) with outstanding results. Although the good
results we encounter low precision stats, this is due to the generic Language
model we used (XLM-RoBERTa), we encountered similar issues in the previous
series [
        <xref ref-type="bibr" rid="ref21">21</xref>
        ]. .
      </p>
      <p>Scenario 1 Scenario 2 Scenario 3
Model Prec. Rec. F1 Prec. Rec. F1 Prec. Rec. F1
Vicomtech 0.541 0.535 0.531 0.700 0.747 0.684 0.542 0.283 0.372
PUCRJ-PUCPR-UFMG 0.568 0.503 0.528 0.715 0.697 0.706 0.367 0.205 0.263
uhKD4 0.485 0.374 0.423 0.518 0.537 0.527 0.556 0.222 0.318
Baseline 0.337 0.177 0.232 0.350 0.272 0.306 0.438 0.017 0.033
IXA 0.465 0.539 0.499 0.614 0.698 0.653 0.454 0.409 0.430</p>
    </sec>
    <sec id="sec-5">
      <title>Conclusions</title>
      <p>
        Simple compositions of ne-tunned FFN and LM can accurately describe the
target language, this is su cient to perform competitively in prediction tasks via
sequence labelling regardless of domain and language, in this way we de ne generic
sequence labelling. We conclude that the sequence labelling task is extensible to
many tasks like seq2seq or classi cation with competitive performance at low
cost as we have seen in several approaches [
        <xref ref-type="bibr" rid="ref21">25, 21</xref>
        ]. This time we expand the
idea enforcing the necessity of new simple mathematical modelling techniques to
handle huge amount of complex data as we have seen in RE task.
learning approaches for knowledge discovery from spanish biomedical documents.
      </p>
      <p>In Proceedings of the Iberian Languages Evaluation Forum (IberLEF 2021), 2021.
25. Edgar Andres Santamar a. End to end approach for i2b2 2012 challenge based on
cross-lingual models. 2020.</p>
    </sec>
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