<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD v1.0 20120330//EN" "JATS-archivearticle1.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>The Adoption Of Arti cial Intelligence In SMEs - A Cross-National Comparison In German And Chinese Healthcare</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Philipp Dumbach</string-name>
          <email>philipp.dumbach@fau.de</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Ruining Liu</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Max Jalowski</string-name>
          <email>max.jalowski@fau.de</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Bjoern M. Esko er</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Chair of Information Systems - Innovation and Value Creation, Friedrich-Alexander-Universtitat Erlangen-Nurnberg (FAU)</institution>
          ,
          <country country="DE">Germany</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Machine Learning and Data Analytics Lab, Department Arti cial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU)</institution>
          ,
          <country country="DE">Germany</country>
        </aff>
      </contrib-group>
      <fpage>84</fpage>
      <lpage>98</lpage>
      <abstract>
        <p>Arti cial Intelligence (AI) as an emerging technology is increasingly applied in the healthcare sector. Moreover, the AI-related progress and technology application is not only driven by traditional companies but even more by the establishment of small and mediumsized enterprises (SME) in healthcare, the innovation process as well as dynamic product development in the very same organizations. We chose a multiple-case study design using expert interviews with 14 SMEs, equally distributed from China and Germany to analyze the adoption of AI in healthcare SMEs. Our results contribute to current empirical research with a cross-national comparison in Germany and China on the status of AI development and adoption, the perceived advantages and challenges of AI, as well as the expected future development and implementation of AI in healthcare in the upcoming ve years.</p>
      </abstract>
      <kwd-group>
        <kwd>Arti cial Intelligence</kwd>
        <kwd>Adoption</kwd>
        <kwd>Healthcare</kwd>
        <kwd>SME</kwd>
        <kwd>Digital Transformation</kwd>
        <kwd>Germany</kwd>
        <kwd>China</kwd>
        <kwd>Bene ts</kwd>
        <kwd>Challenges</kwd>
        <kwd>QualitativeEmpirical Study</kwd>
        <kwd>Interview Study</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>
        Arti cial Intelligence (AI) is rapidly being applied to a wide range of elds,
including healthcare. It has been considered as a technological approach that
may augment or substitute human professionals in healthcare [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. With recent
progress in digitized data acquisition, machine learning, and computing
infrastructure, AI applications are expanding into areas that were thought to be
reserved for human experts [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]. A signi cant application in healthcare is collecting,
storing, normalizing, and tracing data [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ], where AI has the potential for doing
transformative work, such as mining medical records, assisting repetitive jobs [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ],
intelligent decision support in diagnosis or to correct medical decisions [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ]. In
the future, AI could further support digital transformation and revolutionize the
information supply of healthcare practitioners and executives as well as their
interaction with patients, clinical and operational sta [
        <xref ref-type="bibr" rid="ref6 ref7">6, 7</xref>
        ].
      </p>
      <p>
        China is a leading global AI development hub with a vast population and
industry mix that can generate a great data volume and provide an enormous
market [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]. McKinsey Global Institute published a study in 2017, that estimated,
half of all work activities in China could be automated, illustrating the nation's
automation potential [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]. The Chinese State Council issued a guideline in 2018
to improve healthcare service e ciency [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ]. According to the `Made in China
2025' (MIC25) plan, the healthcare sector is prioritized in many ways. AI, one
of the industry-spanning core elements covered by MIC25, is expected to have
a signi cant impact on the transformation of healthcare [
        <xref ref-type="bibr" rid="ref10">10</xref>
        ]. In 2019 China
was Germany's most important trading partner for the fourth year in a row
and both started the deployment in digital technology to create new industrial
environments, produce new products, and improve established brands [
        <xref ref-type="bibr" rid="ref11 ref12">11, 12</xref>
        ].
      </p>
      <p>
        In contrast to various studies on AI applications, e.g. in form of wearable
devices [
        <xref ref-type="bibr" rid="ref13">13</xref>
        ] or autonomous robotics [
        <xref ref-type="bibr" rid="ref14">14</xref>
        ], few studies have spotlighted the
current status of AI development and the prospects of AI technologies from the
company perspective. To ll this research gap, a qualitative-empirical study
using semi-structured interviews was conducted with Chinese and German small
and medium-sized enterprises (SME) in healthcare, especially in micro and small
companies. Compared to global players, startups show signi cant di erences in
acquiring and processing data as well as a di ering philosophy and unique
dynamism [
        <xref ref-type="bibr" rid="ref15">15</xref>
        ]. In total, managers of 14 healthcare SMEs (equally from Germany
and China) were interviewed to investigate the bene ts and challenges regarding
the adoption of AI as well as the future technological development in 5 years'
time, including organizational requirements to adapt for a future with AI.
2
      </p>
    </sec>
    <sec id="sec-2">
      <title>Related Work</title>
      <p>The literature review consists of two parts: rst, we review research on AI in
healthcare in terms of AI-driven applications, challenges in AI development,
and healthcare SMEs. Second, we present an overview of several representative
empirical studies on AI and digitization.
2.1</p>
      <sec id="sec-2-1">
        <title>Arti cial Intelligence in Healthcare</title>
        <p>
          As AI in healthcare becomes more widespread, a wealth of theoretical research
on AI applications is emerging. One of the most prosperous areas to use AI is
automated medical image diagnosis, where AI-powered algorithms have made
inroads in medical specialties including radiology, ophthalmology, pathology, and
dermatology [
          <xref ref-type="bibr" rid="ref16 ref17 ref2">2, 16, 17</xref>
          ]. In addition, wearable devices [
          <xref ref-type="bibr" rid="ref18 ref2">2, 18</xref>
          ], autonomous robotic
surgery, [
          <xref ref-type="bibr" rid="ref14 ref19">14, 19</xref>
          ] and patient care [20{22] are relevant scenarios for AI
applications. Although AI promises to revolutionize medical practice, many challenges
lie ahead. Obermeyer et al. have noted that AI algorithms might `over t'
predictions to spurious correlations in the data, leading to exaggerated claims about
real-world performance. Data from di erent healthcare environments can contain
various types of bias and noise, which may cause a model, trained on one
hospital's data, to fail to generalize to another. They pointed out that the quantity
and quality requirements for input data in AI applications may need an upgrade
of the current databases [
          <xref ref-type="bibr" rid="ref23">23</xref>
          ]. Bartoletti highlighted that AI in healthcare will
also challenge the boundaries of current regulatory systems and privacy
principles. For him, it is essential to adopt a cautious approach in order to maximize
the positive whilst reducing the risks of privacy, bias, and ethics harms [
          <xref ref-type="bibr" rid="ref24">24</xref>
          ].
2.2
        </p>
      </sec>
      <sec id="sec-2-2">
        <title>Empirical Studies</title>
        <p>Compared to the extensive theoretical studies on AI applications, there are
relatively few studies that explore the current status and prospects of applying new
technologies like AI in the form of empirical studies, especially those employing
interviews or questionnaires to collect data. Table 1 shows a brief review.</p>
        <p>Sample Findings
9 (Tai- No clear de nition of smart
wanese) hotel; several barriers that
prohibit hotel owners in
implementing smart systems
18 Stakeholders have diverse, and
(Chinese) sometimes contradictory,</p>
        <p>
          opinions of the challenges
18 Professional norms, tradition,
(British) and culture maintain existing
structures and business models
facing a technological change
40 The development of AI tools in
(French) healthcare would be
satisfactory for everyone only
by initiating a collaborative
e ort between all those involve
20 (Euro- Clear disagreements among
pean) professional stakeholders
regarding solutions for ethical
challenges and the adoption of
strategies to implement IAT
safely and e ectively
48 (US) Patients are receptive to AI for
skin cancer screening if applied
in a manner that preserves
integrity of human
physician-patient relationship
Blease et View of general
al. (2019), practitioner (GP)
[
          <xref ref-type="bibr" rid="ref31">31</xref>
          ] on impact of
future technology
in primary care
Ye et al. Public
(2019), acceptance of
[
          <xref ref-type="bibr" rid="ref32">32</xref>
          ] ophthalmic AI
        </p>
        <p>
          devices
Lackes et A ects on
al. (2020), acceptance of
[
          <xref ref-type="bibr" rid="ref33">33</xref>
          ] intelligent
personal
assistants (IPA)
Berube et Barriers
al. (2021), regarding AI
[
          <xref ref-type="bibr" rid="ref34">34</xref>
          ] implementation
in organizations
        </p>
        <p>Questionnaire 720 Most GPs considered the
(British) potential of AI to be limited
because of the lack of
communication and empathy of
this future technology
Questionnaire 474 Underdeveloped AI use in
(Chinese) clinical laboratory analysis &amp;
diagnostics; mistrust of medical</p>
        <p>AI systems in Chinese public
Questionnaire 129 Trust in the manufacturer
(mainly a ects trust in IPA and
German) perceived advantages; trust in</p>
        <p>
          IPA in uences the perceived
advantages &amp; disadvantages as
well as the acceptance
Interview 18 Lack of data-related
(French, organizational capabilities and
Canadian) of AI experts; generic
implementation barriers
Multiple studies focused on the healthcare industry [28{32], while others
investigated areas like the public sector [
          <xref ref-type="bibr" rid="ref25">25</xref>
          ] or legal [
          <xref ref-type="bibr" rid="ref27">27</xref>
          ]. Various studies used
interviews [25{30, 34], and questionnaires [31{33, 35] to collect data. Regarding the
choice of interviewees or respondents, most researchers looked at stakeholders of
AI technology and products [25{29, 31, 34], or targeted the potential purchasers
of AI products and services [
          <xref ref-type="bibr" rid="ref33 ref35">33, 35</xref>
          ] as well as patients [
          <xref ref-type="bibr" rid="ref30 ref32">30, 32</xref>
          ]. There are few
empirical studies on AI application in healthcare, and to the knowledge of the
authors no studies that considered healthcare SMEs as research subjects.
Furthermore, most studies have sampled from one country rather than making a
cross-national comparison. To ll this research gap, this paper aims for an
alternative perspective by interviewing German and Chinese healthcare SMEs. The
analysis and comparison of the interview results support the further exploration
of AI's development status and adoption in healthcare SMEs in both countries.
3
        </p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>Research Design</title>
      <p>This section describes the research design and the research method, including
data collection and analysis. We apply a case study research approach to answer:
how is the adoption of AI among German and Chinese healthcare SMEs and what
are the di erences between the results of both countries?
3.1</p>
      <sec id="sec-3-1">
        <title>Method</title>
        <p>
          Case studies are a design of inquiry found in many elds. The researcher conducts
an in-depth analysis of a case, often a program, event, activity, process, or one
or more individuals. Cases are bounded by time and activity, and the researcher
uses a variety of data collection procedures to collect detailed information over
a sustained period of time [
          <xref ref-type="bibr" rid="ref36 ref37">36, 37</xref>
          ]. According to Yin [
          <xref ref-type="bibr" rid="ref37">37</xref>
          ], a general de nition of
a case study has two main parts: (a) The scope of a case study: Investigating a
contemporary phenomenon (the \case") in depth and within its real-world
context, especially when the boundaries between phenomenon and context may not
be clearly evident; and (b) a case study's features: The situation where there
will be many more variables of interest than data points, thereby relying on
multiple sources of evidence and bene ting from the development of theoretical
propositions to guide data collection and analysis [
          <xref ref-type="bibr" rid="ref37">37</xref>
          ]. Case studies are
especially suitable when it comes to how and why questions are being asked about a
contemporary set of events over which a researcher has little or no control [
          <xref ref-type="bibr" rid="ref37">37</xref>
          ].
        </p>
        <p>
          We chose a multiple-case study design with expert interviews to collect
primary data. Each case can be represented by an interview that re ects the
company's AI use. The general research procedure is shown in Fig. 1. This owchart,
as described by Yin [
          <xref ref-type="bibr" rid="ref37">37</xref>
          ], illustrates the primary steps of the empirical part.
3.2
        </p>
      </sec>
      <sec id="sec-3-2">
        <title>Setting</title>
        <p>The setting consists of a German and a Chinese perspective (see Fig. 1), which
consist of interviewing suitable experts found in the preparation phase. In total
seven healthcare SMEs from each country were interviewed. Table 2 summarizes
the 14 interviews.</p>
        <p>
          The selection of German interviewees is mainly centered on the members of
the Medical Valley Europaische Metropolregion Nurnberg. It is a leading
international cluster in the eld of medical technology, medicine, and health [
          <xref ref-type="bibr" rid="ref41">41</xref>
          ]. After
G1
G2
G3
G4
G5
G6
G7
C1
C2
C3
C4
C5
C6
C7
2014
2019
2016
2018
2019
2016
2014
2017
2015
2015
2010
2014
2012
2012
15
6
15
53
&lt;10
50
10
180
12
16
20
40
41
        </p>
        <p>Senior Consultant</p>
        <p>CEO
CEO
CEO
CEO</p>
        <p>CEO
Deputy CEO</p>
        <p>Founder/CEO
Co-Founder/CEO</p>
        <p>Erlangen</p>
        <p>Medical Sensor Systems
Managing Director</p>
        <p>Erlangen</p>
        <p>Medical Imaging
Co-Founder/CEO</p>
        <p>Wurzburg</p>
        <p>Surgical Robots
CEO Assistant</p>
        <p>Shanghai</p>
        <p>Medical Service Robots
Location
Munich
Munich
Erlangen</p>
        <p>Furth
Shenyang
Shenyang
Shanghai
Shanghai
Shanghai
Beijing</p>
        <p>Primary Business
Medical Imaging
Structured Data</p>
        <p>Platform
Medical Imaging
Medical Database</p>
        <p>Medical Imaging
Medical Information</p>
        <p>
          Management
Medical Equipment
Asset Management
Medical Imaging
Medical Imaging
Medical Imaging
passing the initial screening the companies were selected as potential
interviewees, and interview invitations were sent to the founders, CEOs, or quali ed
technical sta . For the selection of the Chinese SMEs, an expert
recommendation approach was adopted for optimizing the selection of interviewees. Several
industry experts with in-depth knowledge of and contact with Chinese
healthcare SMEs were chosen as direct contacts who make company recommendations.
The selected potential interviewees were contacted respectively and invited for
the interviews. For Chinese interviewees, WeChat was chosen as the primary
communication tool. Companies were ltered by business type: they had to be
involved in the healthcare industry, and by company size: they had to ful ll the
European Commission's de nition of SME [
          <xref ref-type="bibr" rid="ref42">42</xref>
          ].
3.3
        </p>
      </sec>
      <sec id="sec-3-3">
        <title>Data Collection and Analysis</title>
        <p>
          Case study data collection is crucial and involves a wide range of procedures as
the researcher builds an in-depth picture of the case [
          <xref ref-type="bibr" rid="ref39">39</xref>
          ].
        </p>
        <p>
          Interviews are commonly used in case studies as a form of data collection
to obtain primary data, consisting of asking open-ended questions to
participants [
          <xref ref-type="bibr" rid="ref40">40</xref>
          ]. The interview protocol design follows the procedures from Yin [
          <xref ref-type="bibr" rid="ref37">37</xref>
          ]
and Creswell [
          <xref ref-type="bibr" rid="ref40">40</xref>
          ]. It starts with questions on the AI background and if the
company already applies AI. If they do so, questions are asked about AI
implementation, AI bene ts and challenges, and future possibilities. If they do not
use AI, questions are asked about reasons for not using AI, the general prospect
of AI, and further plans about AI.
        </p>
        <p>
          All interviews were conducted online and recorded with the interviewees'
consent in order to preserve the data for subsequent analysis. A combination of
automatic machine transcription and follow-up manual correction is used in the
transcribing process. The interview languages are English and Chinese. For the
English audio, the transcription is carried out using the automatic speech
recognition function provided by YouTube [
          <xref ref-type="bibr" rid="ref43">43</xref>
          ], whose transcription function has a
lower word error rate and therefore better performance [
          <xref ref-type="bibr" rid="ref44">44</xref>
          ]. For the Chinese
audio processing, a transcription software called iFlytek Hears is chosen [
          <xref ref-type="bibr" rid="ref45">45</xref>
          ].
The interview data is rst transcribed into Chinese text form, and then further
translated into English using the translation software DeepL and manual
corrections. Finally, the English translations are combined with the English interview
transcripts to form the primary data set of this study.
        </p>
        <p>
          Following Yin [
          <xref ref-type="bibr" rid="ref37">37</xref>
          ], the collected data was imported, organized, and analyzed
systematically. After collecting all interview information, the demographic
characteristics of interviewees are summarized to gain an overview of the interviewed
companies. Secondly, each question's results are analyzed as a whole, then
separately within and between countries, to inquire the similarities and di erences.
Speci cally, in the analysis of questions on the bene ts and challenges of AI
use, descriptive analysis is used to count the frequency of the occurrence of each
response among the interviewees, as the responses are relatively homogeneous.
With the results of all interview questions collated and aggregated separately,
the interview questions are then grouped according to the sub-questions they
describe. Among the interview questions, the ones regarding AI background and AI
implementation do not cover speci c research questions. Therefore, the responses
from the two sections are used to measure an overall attitude towards AI among
SMEs. The results are represented in the form of a matrix for a more visualized
exploration in terms of cross-national comparison. For each sub-question, the
corresponding interview questions are summarised and compared to investigate
the di erences in answers between both countries.
4
        </p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>Results</title>
      <p>After presenting the research design and the interviewees, this section will have a
stronger focus on the twelve SMEs (5 German, 7 Chinese) who were declared as
AI adopters. The taxonomy of AI adopters and non-adopters followed out of the
interviewee's answers regarding the AI importance for the companies' business
as well as the organizational capabilities to apply AI.
4.1</p>
      <sec id="sec-4-1">
        <title>Implementation Fields of AI</title>
        <p>Two German (G3, G4) and ve Chinese (C1-4, C6) SMEs considered AI as a core
element and central for their business. Another four rms, two from each country
(G1-2, C5, C7), con rmed the importance of AI but estimated the AI in uence
is still limited. Therefore, AI plays a supporting role in products and services
or is seen in the research and development phase. Three German SMEs (G5-7)
perceived AI as relatively unimportant to their business. Two of those had no
plans to develop AI and according to their lack of capabilities did not apply AI
so far. This study investigated di erent application scenarios in healthcare SMEs
and looked at the AI adoption by the following two dimensions (see Table 3).</p>
        <p>On one hand, the AI usage is classi ed as product component (integration in
products for the optimization of functionalities), or product core which implies
AI as absolutely relevant for the product and its functionality. On the other
hand, two categories of the current stage of AI development are distinguished:
AI in the research stage or AI already applied to products or services.
4.2</p>
      </sec>
      <sec id="sec-4-2">
        <title>Bene ts and Challenges of AI</title>
        <p>Depending on the company background and the current AI development stage,
the German and Chinese experts named multiple bene ts (see Fig. 2) as well
as challenges (see Fig. 3) that accompany the AI implementation within their
organizations. The percentages are calculated separately for the two countries
to eliminate the di erences in the number of interviewees.</p>
        <p>All twelve AI adopters highlighted `e ciency improvement' as a bene t, that
manifests in e.g. speeding up data and image processing (G1-5, C1, C5-7) or
improving management e ciency (C2-4). `Selling point' was mentioned by eight
companies as an advantage to convince investors and to highlight the
innovativeness of AI-driven speci cations. Furthermore, AI is seen as a technology
that leads to better performance compared to humans or traditional algorithms.
Higher accuracy (C4-5, C7), better data processing (G3-4), path planning for
medical robots (C2), or the ability to nd solutions for existing problems (G1)
are linked to this bene t category. Additionally, `talent attraction', `avoidance
of human error' e.g. due to fatigue, `cost reduction' because of fast and accurate
data processing or labour cost savings, and `workload reduction for physicians'
to enable more patient quality time were discussed. Especially regarding the last
four bene ts, a di erentiated view of Chinese and German experts is observed.</p>
        <p>Fig. 2: Bene ts of AI in German and Chinese healthcare SMEs
Similarly, Fig. 3 summarizes the main challenges named by healthcare experts
according to the adoption of AI in their organizations.
Ten interviewees showed a consistent opinion regarding `reliability and
technological limitations', concerning the current AI accuracy and needed
supervision (G3, C1, C5-7) or existing issues of non-reproducibility and robustness in
heterogeneous environments (G2-3). In terms of `data quality', as a result of
non-standardized and unstructured data (G1, G4-5, C1, C5-7), and the lacking
`trust of physicians' in AI products and services (G3-4, C3, C5, C7) experts from
both countries had a mutual understanding. Nevertheless, when looking at `data
accessibility', `transparency &amp; interpretability', e.g. insu cient traceability and
causality of AI decision-making processes, as well as `regulations' and `lack of
experts' the majority of German representatives underlined stronger concerns
compared to Chinese counterparts.
4.3</p>
      </sec>
      <sec id="sec-4-3">
        <title>Prospective AI Development and Non-adopters of AI</title>
        <p>A positive view on the future development of AI in the upcoming ve years was
observed more from Chinese (C2-4, C6) than from German experts (G2, G4).
Chinese representatives expect an increasing trend of AI in the healthcare sector
and a further boost to their business. Activities in Chinese politics to promote
digital transformation and intelligent management in hospitals are seen as
contributions to AI development. From a technical perspective, they still expressed
concerns regarding the maturity of AI applications, e.g. to make autonomous
decisions in the early future. Moreover, German SMEs underlined a prospective AI
development in personalized medicine and within applications to support
diagnostic and therapeutic solutions for individual patients. Healthcare SMEs from
both countries expressed a mixed (G1, C5) or negative view (G3, G5, C1, C7)
when explaining their expectations in the next ve years. Optimism regarding
an increase of AI-related healthcare companies goes along with skepticism when
looking at the cooperation with physicians and the `unlikable replacement' of
physicians in the future. The negative concerns have their origin in the lack of
AI experts and strict regulations, named mainly by German managers.</p>
        <p>As mentioned at the beginning of the results section, there were two
companies (G6-7) that have not adopted AI so far. Both interviewees were neutral
regarding the outlook of AI. On one hand, they could imagine the bene t of AI
in supporting customers to reduce their workload and its ability to potentially
make its own decision. On the other hand, they were pessimistic according to
regulations and their dependence on further research and development in the eld
of AI. Both non-adopters prefer cooperation with external AI-skilled companies
instead of independently deploy AI within their organizations in the future.
5</p>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>Discussion</title>
      <p>
        This study investigated the AI implementation in four areas based on the
dimensions of AI importance and current stage to ll the research gap in empirical
research addressing the AI application in SMEs. After the analysis, no Chinese
and only one German company is located in the area `AI in Research x Product
Component'. The stronger focus especially of Chinese SMEs on AI adoption as
product core and their status being in the AI in use than in the research phase
can be named as reasons. This outcome might be explained by the Chinese
policy to encourage the opening of healthcare data, the digitization of hospitals and
AI in healthcare [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ]. Beyond, no German company is located in the area `AI in
use x Product Core'. This absence is justi ed by the maturity of AI applications
and declared as in research phase or as product component. The situation
reects the stricter regulations in German healthcare industry [
        <xref ref-type="bibr" rid="ref46">46</xref>
        ] and 3-4 years
to conduct a clinical validation and get the medical device certi cation (G3).
      </p>
      <p>
        Experts from both countries had a consistent understanding of three main
AI bene ts when looking at performance and e ciency improvement as well as
AI as a selling point. Nevertheless, German interviewees valued AI more with
80% for its e ect in terms of talent attraction and easier recruitment compared
to only 14% in China. This signi cant di erence could re ect the higher demand
for AI talents in Germany and is evident in the identi ed challenge and lack of AI
experts. These ndings approve previous exploratory studies, which concentrated
on French and Canadian experts and allow a deeper comparison of the national
circumstances [
        <xref ref-type="bibr" rid="ref34">34</xref>
        ]. When looking at AI application elds, a distinct opinion can
be observed. A 57% ratio in China versus 20% in Germany sees the workload
reduction as the main AI bene t. The higher product amount with AI in use in
Chinese companies as well as the stronger focus on physician- than on
patientoriented products and services may explain this outcome.
      </p>
      <p>
        In the perceptions of AI challenges, there are signi cant disparities between
Germany and China. German interviewees not only named more challenges but
also the corresponding percentages when looking at data accessibility as well
as at transparency and interpretability are noticeably higher (80% versus 14%
each). The perception of more barriers to AI use in German healthcare SMEs
may objectively be explained by more di culties in implementing AI (e.g. caused
by stricter data protection laws or healthcare approvals) but also by the
increased desire for a better understanding and explainability of AI. These
ndings go along with the barriers to AI implementation, presented by Berube et
al. [
        <xref ref-type="bibr" rid="ref34">34</xref>
        ], who identi ed the lack of high-quality data and data governance issues
as crucial. They focused on the adoption in all types of organizations. Our study
contributed to close the gap in investigating one particular type and focused on
healthcare SMEs. Meanwhile, it is worth noting that Chinese healthcare SMEs
have relatively easy access to hospital and patient data for example in form of
temporary GPU workstations in order to use images locally.
      </p>
      <p>
        Preparing for a future of AI in healthcare, SMEs agreed on the continuing
optimization of algorithms and of existing AI applications as well as the expansion
to new application areas. New AI technologies need to be tracked and
carefully introduced to the healthcare sector. German and Chinese interviewees plan
to strengthen external collaborations but are following di erent strategies. In
both countries, companies are collaborating with universities and research
laboratories, when cooperating with external AI experts and software companies
healthcare SMEs in China showed stronger activities. These identi ed strategic
approaches show and approve the necessity of collaboration in the eld of AI
between all stakeholders to initiate and increase their e orts for a better transition
from AI in the development phase to its application [
        <xref ref-type="bibr" rid="ref28">28</xref>
        ].
      </p>
    </sec>
    <sec id="sec-6">
      <title>Conclusion, Limitations, and Outlook</title>
      <p>This study concentrated on the adoption of AI in healthcare SMEs, which were
identi ed as an organizational group with a less received focus in previous work.
We contribute to current empirical research with a cross-national comparison of
Germany and China. On the one hand, representatives of both countries
underlined several advantages of the adoption like e ciency improvement or workload
reduction of physicians. On the other hand, various thoughts are necessary
regarding aspects like data quality as well as transparency and accountability to
successfully proceed with the implementation of AI in healthcare organizations.
Especially the German interviewees pointed out a stronger focus on the
challenges within the adoption procedure and had concerns regarding legal
guidelines and questions to be solved in the context of data access and transparency.
In both countries interviewees are expecting a continuing trend within the
upcoming years regarding the integration of AI in new areas and applications in
healthcare, but also a better performance compared to the existing use of AI in
applications. Chinese representatives gave insights in a stronger strategic focus
on future research and development activities, whereas in Germany the
improvement of AI transparency and interpretability is seen as a goal.</p>
      <p>
        There are few limitations that need to be considered for the result
interpretation and for upcoming research. 14 SMEs were equally distributed from
China and Germany. This de nitely gives valuable insights into the healthcare
landscape and the scope of SMEs, but the sample size is not representative for
both countries as a whole. The headquarters of the companies were located in
southern Germany, mainly linked to the Medical Valley. In China, the selected
SMEs stronger represent the eastern part, which is seen as economically more
developed than the western part of the country [
        <xref ref-type="bibr" rid="ref47">47</xref>
        ].
      </p>
      <p>Due to the COVID-19 pandemic all interviews were conducted online, some
without video. The non-face-to-face format might have led to a di erent
interview behaviour of the interviewees and in uenced the interpretation of their
answers without the ability to see the facial expressions and gestures during the
interviews.</p>
      <p>
        As a follow-up to this study, the sample size could be expanded regarding
both countries and views of SMEs compared to those of traditional and
established companies further explored. In addition, the investigation within other
countries could follow the approach of La et al. [
        <xref ref-type="bibr" rid="ref28">28</xref>
        ] who concentrated on French
health professionals instead of SME representatives or addresses AI adoption in
other industries besides its presented in uence in healthcare.
7
      </p>
    </sec>
    <sec id="sec-7">
      <title>Acknowledgements</title>
      <p>Bjoern M. Esko er gratefully acknowledges the support of the German Research
Foundation (DFG) within the framework of the Heisenberg professorship
program (grant number ES 434/8-1).</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          1.
          <string-name>
            <surname>Guan</surname>
          </string-name>
          , J.:
          <source>Arti cial Intelligence in Healthcare and Medicine: Promises, Ethical Challenges and Governance. Chinese Medical Sciences Journal</source>
          <volume>34</volume>
          (
          <issue>2</issue>
          ),
          <volume>76</volume>
          {
          <fpage>83</fpage>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          2.
          <string-name>
            <surname>Yu</surname>
            ,
            <given-names>K.H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Beam</surname>
            ,
            <given-names>A.L.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kohane</surname>
            ,
            <given-names>I.S.:</given-names>
          </string-name>
          <article-title>Arti cial intelligence in healthcare</article-title>
          .
          <source>Nat Biomed Eng</source>
          <volume>2</volume>
          (
          <issue>10</issue>
          ),
          <volume>719</volume>
          {
          <fpage>731</fpage>
          (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref3">
        <mixed-citation>
          3.
          <string-name>
            <surname>Mesko</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          :
          <article-title>The role of arti cial intelligence in precision medicine</article-title>
          .
          <source>Expert Review of Precision Medicine and Drug Development</source>
          <volume>2</volume>
          (
          <issue>5</issue>
          ),
          <fpage>239</fpage>
          -{
          <volume>241</volume>
          (
          <year>2017</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref4">
        <mixed-citation>
          4. The Medical Futurist:
          <article-title>Arti cial Intelligence will redesign Healthcare</article-title>
          . https: //medicalfuturist.com
          <article-title>/arti cial-intelligence-will-redesign-healthcare</article-title>
          .
          <year>August 2016</year>
          .
          <article-title>Last accessed 30 April 2021</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref5">
        <mixed-citation>
          5.
          <string-name>
            <surname>Agah</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          :
          <article-title>Introduction to Medical Applications of Arti cial Intelligence</article-title>
          .
          <source>In: Medical Applications of Arti cial Intelligence</source>
          , pp.
          <volume>1</volume>
          {
          <issue>8</issue>
          . CRC Press, Boca Raton (FL) (
          <year>2013</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref6">
        <mixed-citation>
          6.
          <string-name>
            <surname>Agarwal</surname>
            ,
            <given-names>R.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Gao</surname>
            ,
            <given-names>G.</given-names>
          </string-name>
          , DesRoches,
          <string-name>
            <given-names>C.</given-names>
            ,
            <surname>Jha</surname>
          </string-name>
          ,
          <string-name>
            <surname>A.K.</surname>
          </string-name>
          :
          <article-title>Research commentary|The digital transformation of healthcare: Current status and the road ahead</article-title>
          .
          <source>Information Systems Research</source>
          <volume>21</volume>
          (
          <issue>4</issue>
          ),
          <volume>796</volume>
          {
          <fpage>809</fpage>
          (
          <year>2010</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref7">
        <mixed-citation>
          7.
          <string-name>
            <surname>Garbuio</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lin</surname>
            ,
            <given-names>N.</given-names>
          </string-name>
          :
          <article-title>Arti cial Intelligence as a Growth Engine for Health Care Startups: Emerging Business Models</article-title>
          .
          <source>California Management Review</source>
          <volume>61</volume>
          (
          <issue>2</issue>
          ),
          <volume>59</volume>
          {
          <fpage>83</fpage>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref8">
        <mixed-citation>
          8.
          <string-name>
            <surname>Barton</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Woetzel</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Seong</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Tian</surname>
            ,
            <given-names>Q.</given-names>
          </string-name>
          :
          <article-title>ARTIFICIAL INTELLIGENCE: IMPLICATIONS FOR CHINA</article-title>
          .
          <article-title>McKinsey Global Institute</article-title>
          , Discussion Paper presented at the 2017
          <source>China Development Forum</source>
          , p.
          <volume>20</volume>
          (
          <year>2017</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref9">
        <mixed-citation>
          9.
          <string-name>
            <given-names>The</given-names>
            <surname>State Council General O ce:</surname>
          </string-name>
          <article-title>State Council issues guideline on Internet Plus healthcare</article-title>
          , http://english.www.gov.cn/policies/latest releases/
          <year>2018</year>
          /04/ 28/content 281476127312948.htm.
          <source>April</source>
          <year>2018</year>
          .
          <article-title>Last accessed 5 May 2021</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref10">
        <mixed-citation>
          10.
          <string-name>
            <given-names>Di</given-names>
            <surname>Tommaso</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.R.</given-names>
            ,
            <surname>Spigarelli</surname>
          </string-name>
          ,
          <string-name>
            <given-names>F.</given-names>
            ,
            <surname>Barbieri</surname>
          </string-name>
          ,
          <string-name>
            <given-names>E.</given-names>
            , and
            <surname>Rubini</surname>
          </string-name>
          ,
          <string-name>
            <surname>L.</surname>
          </string-name>
          :
          <article-title>The Globalization of China's Health Industry: Industrial Policies, International Networks and Company Choices. Palgrave Studies of Internationalization in Emerging Markets</article-title>
          , Palgrave Macmillan,
          <string-name>
            <surname>Cham</surname>
          </string-name>
          (
          <year>2020</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref11">
        <mixed-citation>
          11. Statistisches Bundesamt:
          <article-title>China was Germany's most important trading partner in 2019 for the fourth year in a row</article-title>
          , https://www.destatis.de/EN/Press/2020/03/ PE20 080 51.html.
          <source>March</source>
          <year>2020</year>
          .
          <article-title>Last accessed 2 May 2021</article-title>
        </mixed-citation>
      </ref>
      <ref id="ref12">
        <mixed-citation>
          12.
          <string-name>
            <surname>Li</surname>
            ,
            <given-names>L.</given-names>
          </string-name>
          :
          <article-title>China's manufacturing locus in 2025: With a comparison of \Made-in-China 2025" and \Industry 4.0"</article-title>
          .
          <source>Technological Forecasting and Social Change</source>
          <volume>135</volume>
          ,
          <issue>66</issue>
          {
          <fpage>74</fpage>
          (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref13">
        <mixed-citation>
          13. van Vliet,
          <string-name>
            <given-names>M.</given-names>
            ,
            <surname>Donnelly</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.P.</given-names>
            ,
            <surname>Potting</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.M.J.</given-names>
            ,
            <surname>Blijlevens</surname>
          </string-name>
          ,
          <string-name>
            <surname>N.M.A.</surname>
          </string-name>
          :
          <article-title>Continuous noninvasive monitoring of the skin temperature of HSCT recipients</article-title>
          .
          <source>Supportive Care in Cancer</source>
          <volume>18</volume>
          (
          <issue>1</issue>
          ),
          <volume>37</volume>
          {
          <fpage>42</fpage>
          (
          <year>2010</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref14">
        <mixed-citation>
          14.
          <string-name>
            <surname>Gomes</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          :
          <article-title>Surgical robotics: Reviewing the past, analysing the present, imagining the future</article-title>
          .
          <source>Robotics and Computer-Integrated Manufacturing</source>
          <volume>27</volume>
          (
          <issue>2</issue>
          ),
          <volume>261</volume>
          {
          <fpage>266</fpage>
          (
          <year>2011</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref15">
        <mixed-citation>
          15.
          <string-name>
            <surname>Rinsche</surname>
            ,
            <given-names>F.</given-names>
          </string-name>
          :
          <article-title>The Role of Digital Health Care Startups</article-title>
          . In: Schmid,
          <string-name>
            <given-names>A.</given-names>
            ,
            <surname>Singh</surname>
          </string-name>
          ,
          <string-name>
            <surname>S</surname>
          </string-name>
          . (eds.)
          <article-title>Crossing Borders - Innovation in the U.S. Health Care System</article-title>
          , Schriften zur Gesundheitsoekonomie,
          <string-name>
            <surname>P.C.O.</surname>
          </string-name>
          , vol.
          <volume>84</volume>
          , pp.
          <volume>185</volume>
          {
          <issue>195</issue>
          <year>Bayreuth</year>
          (
          <year>2017</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref16">
        <mixed-citation>
          16.
          <string-name>
            <surname>Gulshan</surname>
            ,
            <given-names>V.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Peng</surname>
            ,
            <given-names>L.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Coram</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Stumpe</surname>
            ,
            <given-names>M.C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Wu</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Narayanaswamy</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Venugopalan</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Widner</surname>
            ,
            <given-names>K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Madams</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Cuadros</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kim</surname>
            ,
            <given-names>R.</given-names>
          </string-name>
          :
          <article-title>Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs</article-title>
          .
          <source>JAMA</source>
          <volume>316</volume>
          (
          <issue>22</issue>
          ),
          <volume>2402</volume>
          {
          <fpage>2410</fpage>
          (
          <year>2016</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref17">
        <mixed-citation>
          17.
          <string-name>
            <surname>Mintz</surname>
            ,
            <given-names>Y.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Brodie</surname>
          </string-name>
          , R.:
          <article-title>Introduction to arti cial intelligence in medicine</article-title>
          .
          <source>Minimally Invasive Therapy &amp; Allied Technologies</source>
          <volume>28</volume>
          (
          <issue>2</issue>
          ),
          <volume>73</volume>
          {
          <fpage>81</fpage>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref18">
        <mixed-citation>
          18.
          <string-name>
            <surname>Pevnick</surname>
            ,
            <given-names>J.M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Birkeland</surname>
            ,
            <given-names>K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Zimmer</surname>
            ,
            <given-names>R.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Elad</surname>
            ,
            <given-names>Y.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kedan</surname>
            ,
            <given-names>I.</given-names>
          </string-name>
          :
          <article-title>Wearable technology for cardiology: An update and framework for the future</article-title>
          .
          <source>Trends in Cardiovascular Medicine</source>
          <volume>28</volume>
          (
          <issue>2</issue>
          ),
          <volume>144</volume>
          {
          <fpage>150</fpage>
          (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref19">
        <mixed-citation>
          19.
          <string-name>
            <surname>Peters</surname>
            ,
            <given-names>B.S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Armijo</surname>
            ,
            <given-names>P.R.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Krause</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Choudhury</surname>
            ,
            <given-names>S.A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Oleynikov</surname>
            ,
            <given-names>D.</given-names>
          </string-name>
          :
          <article-title>Review of emerging surgical robotic technology</article-title>
          .
          <source>Surgical Endoscopy</source>
          <volume>32</volume>
          (
          <issue>4</issue>
          ),
          <volume>1636</volume>
          {
          <fpage>1655</fpage>
          (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref20">
        <mixed-citation>
          20.
          <string-name>
            <surname>Celi</surname>
            ,
            <given-names>L.A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Marshall</surname>
            ,
            <given-names>J.D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lai</surname>
            ,
            <given-names>Y.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Stone</surname>
            ,
            <given-names>D.J.</given-names>
          </string-name>
          :
          <source>Disrupting Electronic Health Records Systems: The Next Generation. JMIR Medical Informatics</source>
          <volume>3</volume>
          (
          <issue>4</issue>
          ),
          <year>e34</year>
          (
          <year>2015</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref21">
        <mixed-citation>
          21.
          <string-name>
            <surname>Verghese</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Shah</surname>
            ,
            <given-names>N.H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Harrington</surname>
            ,
            <given-names>R.A.</given-names>
          </string-name>
          :
          <article-title>What This Computer Needs Is a Physician: Humanism and Arti cial Intelligence</article-title>
          .
          <source>JAMA</source>
          <volume>319</volume>
          (
          <issue>1</issue>
          ),
          <volume>19</volume>
          {
          <fpage>20</fpage>
          (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref22">
        <mixed-citation>
          22.
          <string-name>
            <surname>Lin</surname>
            ,
            <given-names>S.Y.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Shanafelt</surname>
          </string-name>
          , T.D.,
          <string-name>
            <surname>Asch</surname>
            ,
            <given-names>S.M.</given-names>
          </string-name>
          :
          <article-title>Reimagining Clinical Documentation With Arti cial Intelligence</article-title>
          .
          <source>In: Mayo Clinic Proceedings</source>
          , vol.
          <volume>93</volume>
          , no.
          <issue>5</issue>
          , pp.
          <fpage>563</fpage>
          -
          <lpage>565</lpage>
          . Elsevier, Stanford, CA (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref23">
        <mixed-citation>
          23.
          <string-name>
            <surname>Obermeyer</surname>
            ,
            <given-names>Z.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Emanuel</surname>
            ,
            <given-names>E.J.</given-names>
          </string-name>
          :
          <source>Predicting the Future | Big Data, Machine Learning, and Clinical Medicine. The New England Journal of Medicine</source>
          <volume>375</volume>
          (
          <issue>13</issue>
          ),
          <volume>1216</volume>
          (
          <year>2016</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref24">
        <mixed-citation>
          24.
          <string-name>
            <surname>Bartoletti</surname>
            ,
            <given-names>I.:</given-names>
          </string-name>
          <article-title>AI in Healthcare: Ethical and Privacy Challenges</article-title>
          . In: Riano,
          <string-name>
            <given-names>D.</given-names>
            ,
            <surname>Wilk</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            , ten
            <surname>Teije</surname>
          </string-name>
          ,
          <string-name>
            <surname>A</surname>
          </string-name>
          . (eds) Arti cial Intelligence in Medicine,
          <source>AIME 2019, Lecture Notes in Computer Science</source>
          , vol
          <volume>11526</volume>
          , pp.
          <volume>7</volume>
          {
          <fpage>10</fpage>
          . Springer, Cham (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref25">
        <mixed-citation>
          25.
          <string-name>
            <surname>Leung</surname>
          </string-name>
          , R.:
          <article-title>Smart hospitality: Taiwan hotel stakeholder perspectives</article-title>
          .
          <source>Tourism Review</source>
          <volume>741</volume>
          ,
          <issue>50</issue>
          {
          <fpage>62</fpage>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref26">
        <mixed-citation>
          26.
          <string-name>
            <surname>Sun</surname>
            ,
            <given-names>T. Q.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Medaglia</surname>
          </string-name>
          , R.:
          <article-title>Mapping the challenges of Arti cial Intelligence in the public sector: Evidence from public healthcare</article-title>
          .
          <source>Government Information Quarterly</source>
          <volume>36</volume>
          (
          <issue>2</issue>
          ),
          <volume>368</volume>
          {
          <fpage>383</fpage>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref27">
        <mixed-citation>
          27.
          <string-name>
            <surname>Brooks</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Gherhes</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Vorley</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          :
          <article-title>Arti cial intelligence in the legal sector: pressures and challenges of transformation</article-title>
          .
          <source>Cambridge Journal of Regions, Economy and Society</source>
          <volume>13</volume>
          (
          <issue>1</issue>
          ),
          <volume>135</volume>
          {
          <fpage>152</fpage>
          (
          <year>2020</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref28">
        <mixed-citation>
          28. La,
          <string-name>
            <given-names>M.C.</given-names>
            ,
            <surname>Brian</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            ,
            <surname>Mamzer</surname>
          </string-name>
          ,
          <string-name>
            <surname>M.F.</surname>
          </string-name>
          :
          <article-title>Perceptions of arti cial intelligence in healthcare: ndings from a qualitative survey study among actors in France</article-title>
          .
          <source>Journal of Translational Medicine</source>
          <volume>18</volume>
          (
          <issue>1</issue>
          ),
          <volume>1</volume>
          {
          <fpage>13</fpage>
          (
          <year>2020</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref29">
        <mixed-citation>
          29.
          <string-name>
            <surname>Wangmo</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lipps</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kressig</surname>
            ,
            <given-names>R.W.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Ienca</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          :
          <article-title>Ethical concerns with the use of intelligent assistive technology: ndings from a qualitative study with professional stakeholders</article-title>
          .
          <source>BMC Medical Ethics</source>
          <volume>20</volume>
          (
          <issue>1</issue>
          ),
          <volume>1</volume>
          {
          <fpage>11</fpage>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref30">
        <mixed-citation>
          30.
          <string-name>
            <surname>Nelson</surname>
            ,
            <given-names>C.A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Perez-Chada</surname>
            ,
            <given-names>L.M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Creadore</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Li</surname>
            ,
            <given-names>S.J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lo</surname>
            ,
            <given-names>K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Manjaly</surname>
            ,
            <given-names>P.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Pournamdari</surname>
            ,
            <given-names>A.B.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Tkachenko</surname>
            ,
            <given-names>E.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Barbieri</surname>
            ,
            <given-names>J.S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Ko</surname>
            ,
            <given-names>J.M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Menon</surname>
            ,
            <given-names>A.V.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Hartman</surname>
            ,
            <given-names>R.I.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Mostaghimi</surname>
            ,
            <given-names>A.</given-names>
          </string-name>
          :
          <article-title>Patient Perspectives on the Use of Arti cial Intelligence for Skin Cancer Screening: A Qualitative Study</article-title>
          .
          <source>JAMA Dermatology</source>
          <volume>156</volume>
          (
          <issue>5</issue>
          ),
          <volume>501</volume>
          {
          <fpage>512</fpage>
          (
          <year>2020</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref31">
        <mixed-citation>
          31.
          <string-name>
            <surname>Blease</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Kaptchuk</surname>
            ,
            <given-names>T.J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Bernstein</surname>
            ,
            <given-names>M.H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Mandl</surname>
            ,
            <given-names>K.D.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Halamka</surname>
            ,
            <given-names>J.D.</given-names>
          </string-name>
          , DesRoches, C.M.:
          <article-title>Arti cial Intelligence and the Future of Primary Care: Exploratory Qualitative Study of UK General Practitioners' Views</article-title>
          .
          <source>Journal of Medical Internet Research</source>
          <volume>21</volume>
          (
          <issue>3</issue>
          ),
          <year>e12802</year>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref32">
        <mixed-citation>
          32.
          <string-name>
            <surname>Ye</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Xue</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>He</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Gu</surname>
            ,
            <given-names>J.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lin</surname>
            ,
            <given-names>H.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Xu</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          , Cheng, Y.:
          <article-title>Psychosocial Factors A ecting Arti cial Intelligence Adoption in Health Care in China: Cross-Sectional Study</article-title>
          .
          <source>Journal of Medical Internet Research</source>
          <volume>21</volume>
          (
          <issue>10</issue>
          ),
          <year>e14316</year>
          (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref33">
        <mixed-citation>
          33.
          <string-name>
            <surname>Lackes</surname>
            ,
            <given-names>R.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Siepermann</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Vetter</surname>
          </string-name>
          , G.:
          <article-title>Can I Help You? { The Acceptance of Intelligent Personal Assistants</article-title>
          . In: Pankowska,
          <string-name>
            <given-names>M.</given-names>
            ,
            <surname>Sandkuhl</surname>
          </string-name>
          ,
          <string-name>
            <surname>K</surname>
          </string-name>
          . (eds.) Perspectives in Business Informatics Research.
          <source>BIR 2019. Lecture Notes in Business Information Processing</source>
          , vol
          <volume>365</volume>
          , pp.
          <fpage>204</fpage>
          -
          <lpage>218</lpage>
          . Springer, Cham (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref34">
        <mixed-citation>
          34.
          <string-name>
            <surname>Berube</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Giannelia</surname>
            ,
            <given-names>T.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Vial</surname>
          </string-name>
          , G.:
          <article-title>Barriers to the Implementation of AI in Organizations: Findings from a Delphi Study</article-title>
          .
          <source>In: Proceedings of the 54th Hawaii International Conference on System Sciences, HICSS</source>
          <year>2021</year>
          , pp.
          <volume>6702</volume>
          {
          <fpage>6711</fpage>
          . (
          <year>2021</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref35">
        <mixed-citation>
          35.
          <string-name>
            <surname>Gross</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Siepermann</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lackes</surname>
            ,
            <given-names>R.</given-names>
          </string-name>
          :
          <article-title>The Acceptance of Smart Home Technology</article-title>
          . In: Buchmann,
          <string-name>
            <given-names>R.A.</given-names>
            ,
            <surname>Polini</surname>
          </string-name>
          ,
          <string-name>
            <given-names>A.</given-names>
            ,
            <surname>Johansson</surname>
          </string-name>
          ,
          <string-name>
            <given-names>B.</given-names>
            ,
            <surname>Karagiannis</surname>
          </string-name>
          ,
          <string-name>
            <surname>D</surname>
          </string-name>
          . (eds.) Perspectives in Business Informatics Research,
          <source>BIR 2020, Lecture Notes in Business Information Processing</source>
          , vol
          <volume>398</volume>
          , pp.
          <volume>3</volume>
          {
          <fpage>18</fpage>
          . Springer, Cham (
          <year>2020</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref36">
        <mixed-citation>
          36.
          <string-name>
            <surname>Stake</surname>
            ,
            <given-names>R.E.</given-names>
          </string-name>
          :
          <source>The Art of Case Study Research. Sage Publications</source>
          , Thousand
          <string-name>
            <surname>Oaks</surname>
          </string-name>
          (
          <year>1995</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref37">
        <mixed-citation>
          37.
          <string-name>
            <surname>Yin</surname>
            ,
            <given-names>R.K.</given-names>
          </string-name>
          :
          <source>Case Study Research and Applications: Design and Methods. 6th edn. Sage Publications</source>
          , Los Angeles (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref38">
        <mixed-citation>
          38.
          <string-name>
            <surname>Denzin</surname>
            ,
            <given-names>N.K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Lincoln</surname>
            ,
            <given-names>Y.S.</given-names>
          </string-name>
          :
          <source>The SAGE Handbook of Qualitative Research. 5th edn. Sage Publications</source>
          , Los Angeles (
          <year>2017</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref39">
        <mixed-citation>
          39.
          <string-name>
            <surname>Creswell</surname>
            ,
            <given-names>J.W.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Poth</surname>
            ,
            <given-names>C.N.</given-names>
          </string-name>
          :
          <source>Qualitative Inquiry &amp; Research Design: Choosing Among Five Approaches. 4th edn. Sage Publications</source>
          , Los Angeles (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref40">
        <mixed-citation>
          40.
          <string-name>
            <surname>Creswell</surname>
            ,
            <given-names>J.W:</given-names>
          </string-name>
          <article-title>30 Essential Skills for the Qualitative Researcher. 1st edn</article-title>
          .
          <source>Sage Publications</source>
          , Los Angeles (
          <year>2016</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref41">
        <mixed-citation>
          41.
          <string-name>
            <surname>Schmidt</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          :
          <article-title>Medical Valley Europaische Metropolregion Nurnberg (EMN): Deutschlands Spitzencluster fur Medizintechnik</article-title>
          . In Pfannstiel,
          <string-name>
            <given-names>M.</given-names>
            ,
            <surname>Focke</surname>
          </string-name>
          ,
          <string-name>
            <given-names>A.</given-names>
            ,
            <surname>Mehlich</surname>
          </string-name>
          , H. (eds)
          <string-name>
            <surname>Management von Gesundheitsregionen</surname>
            <given-names>I</given-names>
          </string-name>
          , pp.
          <volume>21</volume>
          {
          <fpage>27</fpage>
          . Springer Gabler, Wiesbaden, (
          <year>2016</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref42">
        <mixed-citation>
          42. European Commission: SME de nition - Internal
          <string-name>
            <surname>Market</surname>
          </string-name>
          , Industry, Entrepreneurship and SMEs, https://ec.europa.eu/growth/smes/sme-de nitionen.
          <source>Last accessed 20 February 2021</source>
        </mixed-citation>
      </ref>
      <ref id="ref43">
        <mixed-citation>
          43. YouTube Studio:
          <article-title>YouTube translations and transcriptions</article-title>
          , https://studio.youtube. com/channel/translations.
          <source>Last accessed 21 December 2020</source>
        </mixed-citation>
      </ref>
      <ref id="ref44">
        <mixed-citation>
          44.
          <string-name>
            <surname>Kim</surname>
            ,
            <given-names>J.Y.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Liu</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Calvo</surname>
            ,
            <given-names>R.A.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>McCabe</surname>
            ,
            <given-names>K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Taylor</surname>
          </string-name>
          , S.C.R.,
          <string-name>
            <surname>Schuller</surname>
            ,
            <given-names>B.W.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Wu</surname>
            ,
            <given-names>K.</given-names>
          </string-name>
          :
          <article-title>A Comparison of Online Automatic Speech Recognition Systems and the Nonverbal Responses to Unintelligible Speech</article-title>
          . ArXiv, abs/
          <year>1904</year>
          .12403 (
          <year>2019</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref45">
        <mixed-citation>
          45. iFlytek Co., Ltd.:
          <article-title>Xunfei tingjian-professional online voice recording to text software platform | audio recording nishing translation</article-title>
          , https://www.i yrec.
          <source>com. Last accessed 15 January 2021</source>
        </mixed-citation>
      </ref>
      <ref id="ref46">
        <mixed-citation>
          46.
          <string-name>
            <surname>Fischer</surname>
            ,
            <given-names>S.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Leucker</surname>
            ,
            <given-names>M.</given-names>
          </string-name>
          , Luth,
          <string-name>
            <given-names>C.</given-names>
            ,
            <surname>Martinetz</surname>
          </string-name>
          <string-name>
            <given-names>T.</given-names>
            ,
            <surname>Mildner</surname>
          </string-name>
          ,
          <string-name>
            <given-names>R.</given-names>
            ,
            <surname>Nowotka</surname>
          </string-name>
          ,
          <string-name>
            <given-names>D.</given-names>
            ,
            <surname>Steinicke</surname>
          </string-name>
          ,
          <string-name>
            <surname>F.</surname>
          </string-name>
          :
          <article-title>KI-SIGS: Arti cial Intelligence for the Northern German Health Ecosystem</article-title>
          .
          <source>Digitale Welt</source>
          <volume>4</volume>
          (
          <issue>1</issue>
          ),
          <volume>49</volume>
          {
          <fpage>54</fpage>
          (
          <year>2020</year>
          )
        </mixed-citation>
      </ref>
      <ref id="ref47">
        <mixed-citation>
          47.
          <string-name>
            <surname>Crane</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Albrecht</surname>
          </string-name>
          , Ch.,
          <string-name>
            <surname>Du n McKay</surname>
            ,
            <given-names>K.</given-names>
          </string-name>
          ,
          <string-name>
            <surname>Albrecht</surname>
            ,
            <given-names>C.</given-names>
          </string-name>
          :
          <article-title>China's special economic zones: An analysis of policy to reduce regional disparities</article-title>
          .
          <source>Regional Studies, Regional Science</source>
          <volume>5</volume>
          (
          <issue>1</issue>
          ),
          <volume>98</volume>
          {
          <fpage>107</fpage>
          (
          <year>2018</year>
          )
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>