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<article xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>September</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>Investigation of Hybrid Neo-fuzzy Neural Networks in the Problem of Pandemic Forecasting</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Yuriy Zaychenko</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Helen Zaichenko</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Galib Hamidov</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Igor Sikorsky Kyiv Polytechnic Institute</institution>
          ,
          <addr-line>Peremohy av., 37, Kyiv, 03056</addr-line>
          ,
          <country country="UA">Ukraine</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Information Technologies Department</institution>
          ,
          <addr-line>Azershiq, K.Kazimzade 20, Baku, AZ12008</addr-line>
          ,
          <country country="AZ">Azerbaijan</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2021</year>
      </pub-date>
      <volume>2</volume>
      <fpage>8</fpage>
      <lpage>30</lpage>
      <abstract>
        <p>The problem of covid-19 forecasting was considered and investigated. Review of different models and methods of pandemic forecasting are presented. For short-term forecasting indicators of covid-19 the application new class neural networks - hybrid neo-fuzzy networks based on GMDH is suggested. The application of GMDH enables to construct the structure of hybrid network and accelerate the speed of learning neural weights. The experimental investigations were carried out during which the optimal parameters of hybrid network were found sliding window size, forecasting interval and network architecture. The efficiency of hybrid neo-fuzzy network in the pandemic forecasting problem was estimated and compared with Back Propagation neural network.</p>
      </abstract>
      <kwd-group>
        <kwd>1 Covid 19 forecasting</kwd>
        <kwd>hybrid neo-fuzzy network</kwd>
        <kwd>GMDH</kwd>
        <kwd>network parameters and structure optimization</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        In a subsequent study [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ] to predict morbidity and mortality in the United States for long-term, the
researchers used the SEIR model to simulate possible trajectories of severe acute coronavirus syndrome
and the effects of non-drug interventions at the state level from September 22, 2020 to February 28,
2021. Using the SEIR model and forecasts of critical covariances (seasonality of pneumonia, mobility,
per capita testing and use of masks), scenarios of social distancing and the level of mask use were
assessed. Due to its simple structure and speed of use ARIMA model was widely used in forecasting
[
        <xref ref-type="bibr" rid="ref5">5</xref>
        ]. The model takes into account changing trends, periodic changes and random distortions in time
series. The forecast made for Italy, France and Spain showed that covid-19 did not show seasonal
patterns. The best models for Italy, Spain and France were ARIMA (0.2,1), ARIMA (1,2,0) and ARIMA
(0,2,1), respectively.
      </p>
      <p>
        Deep learning models are widely used for Covid-19 forecasting with good results [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ]. In particular,
simple recurrent networks (RNN), long-term short memory (LSTM), bidirectional LSTM (BiLSTM),
gated recurrent units (GRU) and variational autoencoder (VAE) were used to predict covid-19. In a
study of six countries (Italy, Spain, France, China, the United States and Australia), the best result was
shown by the variation autoencoder (VAE). Data since January 22 to May 31, 2020 were taken for the
study. Initially, each model was trained on a training sample.
      </p>
      <p>Comparing the forecasting results, conclusion was made that VAE model showed the best result in
almost all countries except Italy. The average absolute error for Italy is 5.90%, Spain - 2.19%, France
- 1.88%, China - 0.128%, Australia - 0.236% and the United States - 2.04%.</p>
      <p>
        The study [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ] used Back Propagation Neural Network based on a "sliding window" mechanism for
short-term forecasting of four and five days. The absolute average error in Ukraine is 0.65%, and in
Kyiv - 1.33%. The forecasting error appeared to be insignificant.
      </p>
      <p>
        Artificial intelligence methods have been used in the research [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]. The proposed method tracks time
differences in outbreaks in different countries. Data were collected about 250 countries. The neural
network used is a topological autoencoder. Time series of confirmed cases in many countries are
submitted for entry. The system develops a two-dimensional map that projects the topological structures
of dynamics. When forecasting, the system uses a map to find a reference country with similar
dynamics, and then trains the LSTM neural network. The network is taught "with a teacher" or "without
a teacher", or by two methods. Forecasting was carried out for a short period of three days. Comparing
the forecasting results, one can see that in different cases the results vary significantly. Thus, for Brazil
the error reached 3.66%, for Singapore - 2.39%, for New Zealand - 3.72%.
      </p>
      <p>
        In the investigation [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ], a generalized logistic growth model (GLM), a Richards model and a
subepidemic model were used for short-term forecasting of coronavirus. The study was conducted in China
to predict new cases in different provinces. For example, for Guangdong, all three models showed
similar results for the five-day period. The ten-day forecast suggests a small increase in the incidence.
The standard error of forecasting in Guangdong for the GLM model is 36.95-37.63%; for Richard's
model - 35.87-36.95%; for the sub-epidemic model - 35.68-37.46%.
      </p>
      <p>
        Last year’s new class of deep learning networks- hybrid neuro-fuzzy networks [
        <xref ref-type="bibr" rid="ref21">21</xref>
        ] and hybrid
neofuzzy neural networks [
        <xref ref-type="bibr" rid="ref22">22</xref>
        ] were developed and investigated for solution of various problems:
forecasting in macroeconomy and financial sphere, pattern recognition, etc. They are based on
selforganization method GMDH and unlike conventional neural networks enable to train not only weights,
but the network structure as well. Besides, due to a small number of tunable parameters the training
process is accelerated. So, it presents the great interest to apply the hybrid neural networks to the
problem of forecasting the indicators of covid -19 in the process of evolution.
      </p>
      <p>The goal of this paper is to investigate the hybrid neo-fuzzy networks for short-term forecasting of
pandemic indicators in Ukraine, estimate their efficiency and compare with alternating method – neural
network Back Propagation.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Hybrid GMDH-Neuro-Fuzzy System Architecture construction</title>
      <p>
        The general architecture of the hybrid GMDH-network is shown in Fig. 1. The structure hybrid
network is constructed using the principle of self-organization in the following evolution process. To
the input system layer ( × 1)-dimensional vector of input signals  = ( 1,  2,  . . . ,   ) is fed.
(mostly by the mean squared error  2[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]).
      </p>
      <p>
        Then this signal is fed to the first hidden layer that contains  1 =  2 nodes-neurons, each of which
has only two inputs. At the node outputs  [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] of the first hidden layer the output signals  ̂[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ],  =
1,  2, . . . ,  0,5 ( − 1) =  2 are formed. Then these signals are fed to the selection block of the first
hidden layer   [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ], that selects among the output signals  ̂[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]  1 ∗ most precise by accepted criterion


are formed, that are fed to the second hidden layer, formed by neurons  [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ].
      </p>
      <p>
        Among the signals of this layer  ̂[
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] the selection block   [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] selects  best neurons by accuracy
[
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]) if the best signal of the second layer is better than the best one of the first hidden
(e.g., by value of  2


layer  ̂1[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] ∗. Other hidden layers forms signal similarly to the second layer.
      </p>
      <p>The system evolution process continues until the best signal of the selection block   [ +1] would be
worse than the best signal of the previous  th layer, that is  2

 [ +1]&gt;  2[ ].</p>
      <p />
      <p>
        Then we return to the previous layer and choose its best node neuron  [ ] in order to form the system
output signal  ̂[ ]. And moving from this neuron (node) along its connections backward and
sequentially passing all previous layers we determine the structure of GMDH-neuro-fuzzy network. As
nodes of hybrid fuzzy network neo-fuzzy neurons with inputs are used [
        <xref ref-type="bibr" rid="ref20">20</xref>
        ]. Their main advantage is
the lack of necessity to train membership functions and only weights of rules are adapted during the
learning. It should be stressed that we obtain not only optimal network structure but also well-trained
network due to the GMDH algorithm. Besides, since the training is performed sequentially layer by
layer the problems of high dimensionality as well as vanishing or exploding gradient are absent. This
is very important for deep learning networks.
      </p>
    </sec>
    <sec id="sec-3">
      <title>3. Software and initial data description</title>
      <p>
        The programming language was chosen on the basis of the following criteria: ease of performing
mathematical calculations, prevalence, cross-platform and purity of syntax. The most suitable for these
criteria was the Python programming language [
        <xref ref-type="bibr" rid="ref14 ref15">14, 15</xref>
        ], which has gained great popularity in recent
years. It is worth noting that the Python language gained popularity at a time when developers began to
actively use neural networks to solve various problems, resulting in a large number of libraries and
modules that simplify mathematical calculations or implement the logic of individual algorithms.
      </p>
      <p>
        The development environment was chosen in terms of the cost of the license, the ease of writing
software code and the availability of extensions to optimize performance. As a result, the PyCharm
environment was chosen [
        <xref ref-type="bibr" rid="ref15">15</xref>
        ]. It is also important that PyCharm is operating system independent and
has useful extensions that help reduce code writing time and control development. Extensions can be
installed as needed or run without their use.
      </p>
      <p>
        Scikit learn was chosen as a library for machine learning [
        <xref ref-type="bibr" rid="ref18">18</xref>
        ]. It is the most common for machine
learning problems. This library allows you to work with tensors, perform complex mathematical
operations for the scientific and technical field, provides tools for visualization of data processing and
analysis.
      </p>
      <p>
        The SciKit-Fuzzy library [
        <xref ref-type="bibr" rid="ref19">19</xref>
        ], which is essentially a set of algorithms, was chosen to work with
fuzzy logic. The benefit of this library is that with its use it is possible to use a set of common
membership functions, to introduce fuzzy, to perform operations of clarity.
      </p>
      <p>Thus, the main tools for creating a software product that are free and popular were chosen.
The program consists of three main modules:
Module for working with data sets and auxiliary functions
Module for working with GMDH neo fuzzy
Module for working with Back Propagation</p>
      <p>
        Statistical data is processed in several successive stages: obtaining data from the resource, preparing
and saving a file with time series, generating graphs based on the obtained time series and creating data
sets for training. The API of the National Security and Defense Council of Ukraine was chosen as a
resource for obtaining statistical data [
        <xref ref-type="bibr" rid="ref20">20</xref>
        ]. When contacting this service, it is possible to obtain detailed
information about the level of COVID-19, for forecasting the following indicators were selected: the
number of confirmed cases, recovered and dead. Values of these indicators for the period from March
12, 2020 to April 19, 2021 were used.
      </p>
      <p>Thus, absolute indicators were obtained, and a graph of their dynamics was constructed on the time
interval and presented in the Fig. 2.</p>
      <p>The daily increase of indicators was also chosen for forecasting, for which the necessary requests to
the service were created, the obtained data were saved, and the corresponding flow chart was
constructed (Fig. 3).</p>
      <p>Before training, the data were normalized, i.e. subjected to some transformation, so that it was
possible to apply mathematical algorithms to work with them.</p>
      <p>After training neural networks, as well as after forecasting, it is possible to generate reports that
contain detailed information about the processes that took place and the results of work. Such reports
include a table comparing forecast values with real ones and a calculated criterion MAPE.</p>
    </sec>
    <sec id="sec-4">
      <title>4. Experimental investigations of hybrid neo-fuzzy network</title>
      <p>To obtain the most accurate prediction, the optimal neural network parameters were determined, at
which the MAPE values were the best. For this goal the following parameters were successively
changed: membership function (bell-shaped, Gaussian, sigmoid, triangular), number of inputs (3, 4, 5,
6) and short-term forecast period (5, 6, 7, 8). It should be noted that the number of inputs is a small
number, because it depends on the size of the neural network, which affects the computational costs of
training. Determination of optimal parameters was performed for absolute values and daily growth of
indicators.
4.1.</p>
    </sec>
    <sec id="sec-5">
      <title>Investigations of membership functions influence</title>
      <p>In the first experiment the influence of membership functions on prediction accuracy was explored.
The corresponding results for the absolute values of the number of confirmed cases, is presented in the
Table 1. As it follows the best value of MAPE was found when using the Gaussian function (1).
Bellshaped and sigmoidal functions showed almost identical results.</p>
      <p>In the Table 2 MAPE criteria for prediction absolute values of the number of recovered and in the
Table 3 – for prediction number of deaths are shown. As it follows the most accurate forecast was
achieved with the bell-wise membership function.</p>
      <p>The value of MAPE was the lowest when using the sigmoidal membership functions to predict the
absolute values of the number of deaths (Table 3). While forecasting the daily increase in the number
of confirmed cases, the best MAPE value was obtained using the Gaussian function (Table 4).</p>
      <p>The forecast of the daily increase in the number of recovered was the most accurate for the triangular
membership function (Table 5). The best option is also to use the Gaussian function in this case and the
worst results were shown by the sigmoidal function.</p>
      <sec id="sec-5-1">
        <title>Membership functions</title>
      </sec>
      <sec id="sec-5-2">
        <title>Bell-wise</title>
      </sec>
      <sec id="sec-5-3">
        <title>Gaussian sigmoidal triangular</title>
      </sec>
      <sec id="sec-5-4">
        <title>Membership functions</title>
      </sec>
      <sec id="sec-5-5">
        <title>Bell-wise</title>
      </sec>
      <sec id="sec-5-6">
        <title>Gaussian sigmoidal triangular</title>
        <p>To predict the daily increase in the number of deaths, the lowest value of MAPE was for the
triangular membership function, but the bell-shaped function also showed not much worse results. So,
after these experiments the adequate membership functions were determined to predict all indicators of
covid-19.
4.2.</p>
      </sec>
    </sec>
    <sec id="sec-6">
      <title>Investigation of optimal number of inputs</title>
      <p>In the next series of experiments the investigation of optimal inputs number for forecasting
covid19 indicators were performed. The results of experiments- dependence MAPE values on inputs number
for absolute number of confirmed cases are presented in the table 6, for absolute number of deaths- in
the table 7 and for absolute number of recovered- in the table 8.</p>
      <sec id="sec-6-1">
        <title>Number of inputs</title>
        <p>3
4
5
6</p>
        <p>For the daily increase in the number of recovered and died forecast the optimal number of inputs is
equal to 6. As result of these experiments the optimal values of inputs number were determined to
forecast of absolute values and daily increase of indicators.
4.3.</p>
      </sec>
    </sec>
    <sec id="sec-7">
      <title>Estimation of forecast accuracy for different short-term periods</title>
      <p>In the subsequent experiments the forecasting period (interval) was investigated for absolute and
daily indicators of covid-19. The corresponding results are presented in the Tables10-12. To predict
the absolute values of the number of recovered the optimal period was 6 days, but the accuracy for all
periods was approximately the same (Table 11).</p>
      <sec id="sec-7-1">
        <title>Period, days</title>
      </sec>
      <sec id="sec-7-2">
        <title>Period, days</title>
        <p>Period, days</p>
        <p>The forecast of daily increase in the number of confirmed cases was the best for the period of 5
days (Table 12). The corresponding results when forecasting daily increase in covid-19 indicators are
presented in the Table 13. The predicted values of the daily increase in the number of recovered were
more accurate for the period of 5 days, and the worst were the periods of 7 and 8 days, and the values
of MAPE for them are approximately the same, but they differ significantly from the best case.</p>
      </sec>
    </sec>
    <sec id="sec-8">
      <title>5. Neural network Back Propagation for Covid-19 forecasting</title>
    </sec>
    <sec id="sec-9">
      <title>5.1. Experimental investigations of NN Back Propagation</title>
      <p>The neural network Back Propagation (NNBP) is a universal approximator because it can
approximate any continuous nonlinear bounded function from n variables Y = F (x1, x2,…, xn). It’s
property is used to build a forecast.</p>
      <p>The architecture of NNBP which was considered in this paper consists of four layers: input layer:
the number of neurons depends on the training sample, namely the value of the sliding window; hidden
layer 1: contains 16 neurons; hidden layer 2: contains 8 neurons; output layer: has one output.</p>
      <p>The activation functions for latent layer neurons and the source layer neuron are the same and are
sigmoidal. A gradient descent algorithm was used to train the neural network. To assess the accuracy
of the forecast, we used the same criterion of MAPE like hybrid neo-fuzzy network.</p>
      <p>The forecast of absolute values and daily growth of indicators using the optimum parameters
determined in previous section 3 was carried out. That is, the value of the sliding window was taken as
the number of inputs for the case. The forecasting period was similarly chosen. Each case was explored
at a different percentage of the training sample in order to obtain better forecasting results. The
percentage of the training sample was 60%, 70%, 80%, and the test sample remained, respectively,
40%, 30%, 20% of the whole data sample.</p>
      <p>To determine the best forecast in addition to the value of MAPE as an additional criterion was taken
the number of epochs for learning, but in the selection of the best forecast it was not taken into account.
The number of epochs of learning was considered to be the number of the last epoch, after which the
value of the loss function didn’t not improve. In this case training was stopped, and the weights of the
neurons were restored to the corresponding values. The experimental results for forecasting covid-19
indicators for NN Back Propagation are presented in Tables 14-16.</p>
      <p>In the case of predicting the number of deaths, the most accurate forecast was using 80% training
sample (Table 16).</p>
      <sec id="sec-9-1">
        <title>Training sample,%, % 60 70 80</title>
      </sec>
      <sec id="sec-9-2">
        <title>Number of epochs 741 87 34</title>
        <p>The highest accuracy of the forecast of the number of recovered was achieved at 80% training
sample, and training lasted 36 epochs.</p>
      </sec>
    </sec>
    <sec id="sec-10">
      <title>Comparison of forecasting results of hybrid NFN and Back Propagation</title>
      <p>For the convenience of forecasting efficiency estimation the comparison of the forecasting results
by hybrid neo-fuzzy neural network and NN Back Propagation are presented in the Table 17.</p>
      <p>Analyzing the results of Table 17 the following conclusions are made.</p>
      <p>Hybrid neo-fuzzy network appears to be better than NN BP when forecasting absolute (integral)
values of covid indicators while NN Back propagation is better for forecasting daily increase in
covid19 indicators.</p>
      <p>It should be noted that the values of MAPE in predicting the daily increase in the number of
confirmed cases and recovered have a relatively small difference for both neural networks. A significant
difference is observed for MAPE in predicting the absolute and daily increase values of the number of
died. If to pay attention to the size of the sliding window, one may conclude that its smaller value
ensures greater accuracy in the case of forecasting using GMDH- neo fuzzy network.</p>
    </sec>
    <sec id="sec-11">
      <title>6. Synthesis of optimal structure of hybrid GMDH neo fuzzy network</title>
      <p>The GMDH method was used to synthesize the structure of the hybrid network based on the principle
of self-organization. The successive increase in the number of layers is carried out until the value of the
external criterion of optimality MSE begins to increase for the best model of the current layer. In this
case it is necessary to return to the previous layer, to find there the best model with the minimum value
of criterion. Then we move backward, go through its connections, find the corresponding neurons of
the previous layer. This process continues until we reach the first layer and the corresponding structure
is automatically determined.</p>
      <p>The process of synthesis of the network structure in the forward direction is shown in Fig. 3 where
in green color the outputs which passed through selection block (SB)are shown while in red color
outputs which were dropped (excluded) by SB.</p>
      <p>The process of restoring the desired structure in the backward direction is shown in Fig. 4. In yellow
color nodes and their connections selected by this process are indicated.</p>
      <p>The corresponding optimal synthesized structure of the hybrid network for this forecasting problem
is shown in Fig. 5.</p>
      <p>It consists of 3 layers: first layer has 3 neo-fuzzy neurons, second layer - two neurons and the
lastone neuron.</p>
    </sec>
    <sec id="sec-12">
      <title>7. Conclusions</title>
      <p>In this paper the problem of short-term covid-19 forecasting is considered and investigated. For its
solution a new class of NN – hybrid neo-fuzzy network based on self- organization is suggested.</p>
      <p>The experimental investigations of hybrid NFN were carried out. In the results of experiments the
optimal parameters of hybrid network were found: membership functions, number of inputs and
forecasting interval. Optimal structure of hybrid neo-fuzzy network was constructed using GMDH
method.</p>
      <p>The experimental investigations of hybrid NFN in short-term forecasting covid-19 indicators, incl.
confirmed cases, number of recovered and died -were performed and forecasting efficiency was
estimated. The forecasting accuracy of hybrid NFN was compared with NN Back Propagation.</p>
      <p>As a whole hybrid neo-fuzzy neural network appeared to be the efficient tools for short-term
pandemic indicators forecasting.</p>
    </sec>
    <sec id="sec-13">
      <title>8. References</title>
    </sec>
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