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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>News Coverage using Medical NLP</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Ali Emre Varol</string-name>
          <email>emre@johnsnowlabs.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Veysel Kocaman</string-name>
          <email>veysel@johnsnowlabs.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Hasham Ul Haq</string-name>
          <email>hasham@johnsnowlabs.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>David Talby</string-name>
          <email>david@johnsnowlabs.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>John Snow Labs inc.</institution>
          <addr-line>16192 Coastal Highway, Lewes, DE 19958</addr-line>
          ,
          <country country="US">USA</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2022</year>
      </pub-date>
      <abstract>
        <p>Being a global pandemic, the COVID-19 outbreak received global media attention. In this study, we analyze news publications from CNN and The Guardian - two of the world's most influential media organizations. The dataset includes more than 36,000 articles, analyzed using the clinical and biomedical Natural Language Processing (NLP) models from the Spark NLP for Healthcare library, which enables a deeper analysis of medical concepts than previously achieved. The analysis covers key entities and phrases, observed biases, and change over time in news coverage by correlating mined medical symptoms, procedures, drugs, and guidance with commonly mentioned demographic and occupational groups. Another analysis is of extracted Adverse Drug Events about drug and vaccine manufacturers, which when reported by major news outlets has an impact on vaccine hesitancy.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - commonly known
as COVID-19 - was first reported in December 2019. Due to its highly contagious nature,
it quickly spread through the world, prompting the World Health Organization to declare
the virus outbreak as a global pandemic on March 11, 2020 [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. As news media reporting is
understood to play a central role during national security and health emergencies [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ], during the
pandemic, media representations of complex, rapidly evolving epidemiological science shape
public understandings of the risks, measures to limit disease spread, and associated political
and policy discourses [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ].
      </p>
      <p>
        In this study we analyse news coverage from two prominent media outlets: CNN and The
Guardian. The dataset includes more than 36,000 articles and is analyzed using the clinical
and biomedical NLP models from the Spark NLP for Healthcare library [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. Spark NLP is an
open-source and widely deployed software library, built on top of Apache Spark, that provides
production-grade implementations of recent deep learning and transfer learning NLP algorithms
and models. It enables combining tasks into unified NLP pipelines in Python, R, Java, or Scala
and is the only library that can scale up training and inference on any Spark cluster. Spark NLP
for Healthcare provides healthcare-specific algorithms and over 400 pre-trained models that
have obtained state-of-the-art accuracy on public academic benchmarks in biomedical named
entity recognition [5], clinical assertion status detection [6], medical relation extraction [7], and
adverse event detection [8].
      </p>
      <p>COVID-19 has been studied extensively - including the impact of its news coverage. In
previous studies, [9] and [10] used topic modelling and sentiment analysis, while [11] analyzed
discourse structures to study bias in media reporting to influence government policies and global
reporting. Cresswell et al. [12] used social media data to analyse public sentiment towards the
pandemic and determined media reporting played a major role in public sentiment. This study
is unique in applying healthcare-specific deep learning networks, models, and embeddings
enabling the extraction and correlation of over 100 diferent types of medical entities with high
accuracy. Following are the contributions of this study:
• Using fine-tuned NLP models to find most prevalent covid symptoms, prevention
guidelines, research institutions, covid variants, and other entities for analysis.
• Geographical and demographic analysis of news coverage to understand most afected
countries, population age groups, and professions.
• Putting the entire covid coverage of 2020 &amp; 2021 on a timeline for each country, to
understand temporal variation and correlation of case count and media coverage.
• Comparing the findings from unstructured text with the statistical data reported by WHO
and analysing coherency.
• Correlating adverse reactions and drug brands by extracting and linking drug and reaction
entities.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Analysis</title>
      <p>The dataset comprises of 36,354 live blogs and key moments about COVID-19, published in
2020 and 2021. A live blog is a web page where news media outlets ofer daily live coverage
about an ongoing event. Each live blog consists of news stories and key moments. Journalists
manually select the key moment stories from the whole set of news articles. We excluded
the key moments from live blogs; hence, we can appropriately compare live blogs with key
moments; otherwise, there will be some overlapping parts. To scrape the news articles, we
leveraged web scraping algorithms by [13], and updated according to our use-case. Updated
code and Spark NLP pipelines can be accessed [14]. As stated in [13], first, we collected the live
blogs and then applied some pre-processing steps such as parsing HTML format, converting
the dates, and extracting key moments from live blogs. The data is organized by title, text,
date, URL, and key moment status fields. After data preparation, the executed NLP pipeline
included sentence segmentation, tokenization, calculating embeddings, multiple named entity
recognition steps, and relation extraction.</p>
      <p>In the following sections, we’ll report the analysis outcomes that we run over the news
coverage by age demographics, news cycle evolution over time and the reporting and impact of
adverse drug &amp; vaccine events.</p>
      <sec id="sec-2-1">
        <title>2.1. General News Analysis</title>
        <p>We tracked the live blogs of CNN from 22nd January 2020 and The Guardian from 24th January
2020; until the end of 2021. The distribution of news by sites and years is explained in Figure
1. Upon inspection, it is apparent that the number of news was high in the periods when
COVID-19 first appeared and the first deaths had been reported in and outside Asia in early
2020. News of CNN reached its peak point in March 2020 when COVID-19 reached the shores
of United States. Other factors of high news coverage included the massive spread in Europe
(especially Italy) and promulgation of the virus as a pandemic by the WHO. Conspicuously,
CNN COVID-19 reporting gradually decreased after their peak point and became very seldom
in late 2021. With all these, as an overall evaluation, a monthly average of COVID-19 live blogs
and key moments is 807, and the median is 365.</p>
        <p>If we look at the types of news, it primarily consists of live blogs while the key moments
constitute for a minority portion. When we combine them for analysis, we get more than 5.3M
words in the corpus to create a story.</p>
      </sec>
      <sec id="sec-2-2">
        <title>2.2. Demographics and Geographical Analysis by Named Entities</title>
        <p>In order to analyse the news coverage by certain geographical entities, we used a pre-trained
named entity recognition (NER) model called ner_deid1 from Spark NLP for Healthcare library
to extract country names mentioned in the news. Using WHO’s oficial daily statistics [ 15], we
gathered the number of actual COVID-19 cases and deaths for every half of 2020 and 2021, and
then compared with the top 12 countries extracted from the news by the ner_deid model.</p>
        <p>Figure 2 shows the normalized metric for each country by dividing its value by the maximum
value in the respective six-month period. As it is seen on the chart, the most reported cases are
1https://nlp.johnsnowlabs.com/2021/09/03/ner_deid_subentity_augmented_en.html
seen in the USA, India, and Brazil, respectively. It is also seen that the number of patients who
died is also among these three countries, although Brazil ranks second on the death list.</p>
        <p>The graph can be interpreted in the following way: (1) If the lengths of the bars are in
agreement with each other, it can be deduced that the cases reported and deaths reported are in
agreement with the number of news broadcasts in CNN and the Guardian. (2) If the blue and
red bars are compatible with each other but not with the green bar, there may be two reasons
for a mismatch with the news number. The first reason could be that the country is far from
the news source while the second reason could be that the total number of cases and deaths
in the country are not considered remarkable by the news sources. (3) If the all the bars are
inconsistent with each other, it may indicate that the country in question has not published the
case and death numbers transparently. (4) Needless to say, the numbers regarding the countries
having inconsistent figures (e.g. Brazil, Russia etc.) might also be explained by the fact that
the dataset only covers the news articles from the US (CNN) and UK (Guardian), hence these
countries are reported through the lens of other countries (US and UK editors).</p>
        <p>Consequently, we can count United States, United Kingdom, France, Germany and Australia
as the most compatible countries while China and Brazil can be counted as the most incompatible
countries. For Spain, the total number of cases and deaths is consistent, but the volume of news
articles is inconsistent. This may be explained by Spain being away from the two news sources.</p>
      </sec>
      <sec id="sec-2-3">
        <title>2.3. Behavioral and Clinical Analysis by Named Entities</title>
        <p>In order to analyse the news with respect to the clinical entities mentioned, we used a pretrained
NER model named ner_events_clinical2 and ner_jsl3 to extract major clinical events. These two
NER models combined can extract more than one hundred diferent types of clinical entities at
once, with one line of code, enabling a deeper analysis than previous studies of this type.</p>
        <p>Figure 3 shows the top 40 entities by frequencies in the corpus. Entities related to coronavirus
(deaths, infections, preventive measures, and geographical locations etc) seem to be the most
prevalent, followed by entities related to research and development of drugs. When we look at
the ranking of countries in this list, the United States holds first place with the most reported
number of cases, while the United Kingdom and Italy are in the second and third places - aligning
with the WHO stats illustrated in Figure 2. The only university listed is John Hopkins University
(JHU), primarily because of its role in organization and coordination of the Coronavirus Resource
Center [16]. We also see major vaccine manufacturers in the list due to high coverage of vaccine
development and trials.</p>
        <p>Figure 4 shows the Top 10 treatments, symptoms, drugs, and procedures in the order of
their frequencies. It is clear that concepts like vaccine, wearing masks, oxygen support, and
ventilators appear often in treatments. These entities along with isolation, quarantine, social
distancing, and self-isolation, which are at diferent ranks in the list, have a significant place in
disease control.</p>
        <p>On the other hand, the symptoms presented in Figure 4 are widespread. People who observe
2https://nlp.johnsnowlabs.com/2021/03/31/ner_events_clinical_en.html
3https://nlp.johnsnowlabs.com/2020/04/22/ner_jsl_en.html
any of these symptoms turn to hospitals or health institutions to find out if they have COVID-19.
Coughing, blood clotting, sneezing, fatigue, shortness of breath, and headache are the prevailing
COVID-19 symptoms. It is worth noting that even a headache alone was enough to arouse the
suspicion of coronavirus during this period. However, very specific symptoms related to loss of
smell and taste are also observed, although their frequency is lower.</p>
        <p>When analyzing named entities related to drugs, the companies producing vaccines stand
out. Note that drug names also include drug brand names, drug manufacturers, and drug
ingredients. The data suggests that the manufacturer’s name is more prominent compared
to the drug’s scientific name in news coverage. Hydroxychloroquine and chloroquine were
granted an emergency use authorization (EUA) on March 28, 2020 for treating COVID-19 cases.
However, on June 15, 2020, FDA revoked its use [17], limiting it only to hospitalized patients
under heart monitoring.</p>
        <p>The most commonly mentioned medical procedures feature intubation and inoculation in
the top two places. Intubation has been the most frequently applied procedure for patients
admitted to the intensive care unit during this period.</p>
        <p>The pie chart in Figure 5 shows that the most mentioned age group is 60 years and above,
followed by adolescents. This is probably due to the fact that COVID-19 has higher severity in
older people. According to scientific observations, WHO declared that COVID-19 is often more
severe in people who are older than 60 years or who have health conditions like lung or heart
disease, diabetes, or conditions that afect their immune system [ 18].</p>
        <p>Comparing the most prevalent entities in 2020 versus 2021 - the coronavirus, which was
in the first place in 2020, fell to second place in 2021, ceding the first place to the COVID-19
vaccine. The word ’reported’ fell from the second most encountered entity in 2020 to the fourth
in 2021. This decline can be attributed to less willingness to reporting of COVID-19 cases since
according the [19] the trend of reported cases is not declining. On the contrary, there is an
increase in both the number of new cases and the number of deaths.</p>
        <p>In addition to healthcare-specific named entity recognition and resolution models, Spark NLP
also provides unsupervised key phrase extraction from free text. Results indicate that the entity
counts follow the general trend where COVID-19 infection is the most prevalent term, followed
by entities related to death, geographical locations, media outlets, vaccine development, and
vaccination reports.</p>
        <p>COVID-19 also highlighted specific professions namely the medical doctors and nurses. Our
NER analysis show that researchers, workers, teachers and government oficials are the most
cited professions in the news. Understandably, the most commonly mentioned people in the
news during this period are healthcare professionals.</p>
      </sec>
      <sec id="sec-2-4">
        <title>2.4. Impact of Adverse Drug and Vaccine Events</title>
        <p>Adverse drug reactions/events (ADR/ADE) have a major impact on patient outcomes and
healthcare costs. An analysis of extracted Adverse Drug Events versus drug and vaccine
manufacturers reported by major news outlets has an impact on vaccine hesitancy as well
as people’s reactions to medications and public health measurements dictated by regulatory
agencies. In order to analyse ADEs as well the adverse events of vaccines mentioned in the
news, we used a pre-trained NLP pipeline named explain_clinical_doc_ade4 that comes with the
Spark NLP for Healthcare library. This NLP pipeline is the first scalable end-to-end solution
for mining ADE’s from unstructured text, including Document Classification, Named Entity
Recognition, and Relation Extraction Models within a unified NLP pipeline [ 8].</p>
        <p>Figure 6 is a heatmap of correlation between vaccines and adverse reactions. When we
explore the news dataset, we see that some of the vaccines are listed as their manufacturer’s
name, but some are only with generic titles such as COVID-19 vaccine or mRNA vaccines. Since
the heavy use of such general entities dilutes the results, Figure 7 shows the correlation while
eliminating general vaccine names.</p>
        <p>One of the most prominent observation the entanglement of clotting with AstraZeneca and
Johnson &amp; Johnson. This phenomenon was widely reported by the media, suspending the use
of the drugs by these companies [20]. General allergic reactions are more common for vaccines
from Pfizer &amp; BioNTech and Moderna [ 21].</p>
        <p>4https://nlp.johnsnowlabs.com/2021/07/15/explain_clinical_doc_ade_en.html</p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>3. Conclusion</title>
      <p>As a global pandemic, COVID-19 has caused millions of deaths and impacted most people on
earth. The media has played a major role in shaping public awareness, education, and opinion.
Due to the growing number of media channels, the constant barrage of news, the prevalence of
social media in sharing and shaping the news, and frequent shifts in regulations dictated by
governments to combat the pandemic, analysing such a sheer volume of information objectively
in a short amount of time can be one of the most practical current applications of NLP. In this
study, we analyse news coverage from two prominent media outlets by using the clinical and
biomedical NLP models of Spark NLP for Healthcare.</p>
      <p>The analysis shows that the total number of cases and deaths reported by the news are mostly
consistent with the numbers shared by WHO oficially. The pre-trained NLP models perform
well on extracting the most relevant terms and entities that have been widely used in the news.
One tangible outcome of this study can be the automated mining of the adverse reactions to
drugs and vaccines that are used to combat the virus. The analysis shows the correlations
between the prominent vaccine manufacturers and reported adverse events just by relying on
the news articles used for this study. Future research can broaden this automated analysis to
include additional news sources, news in languages other than English, dealing with fake news,
or to correlating changes in news coverage to resulting changes in public opinion and behavior.
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