=Paper=
{{Paper
|id=Vol-3200/paper26
|storemode=property
|title=Information Technology for Identification of Electric Stimulating Effects Parameters
|pdfUrl=https://ceur-ws.org/Vol-3200/paper26.pdf
|volume=Vol-3200
|authors=Volodymyr Fedorchenko,Igor Prasol,Olha Yeroshenko
}}
==Information Technology for Identification of Electric Stimulating Effects Parameters ==
Information Technology for Identification of Electric Stimulating Effects Parameters Volodymyr Fedorchenko, Igor Prasol and Olha Yeroshenko Kharkiv National University of Radio Electronics, Nauky Ave. 14, Kharkiv, 61166, Ukraine Abstract A wide range of modern therapeutic devices based on various physical principles, widely used in medicine, cosmetology, sports. Among them, electric massage devices occupy a worthy place, alternative to classic manual massage. Therapeutic electromassage procedures are popular, convenient and beneficial for the recovery of the body. They are widely used in the treatment of chronic diseases of the circulatory system, musculoskeletal system, internal organs, etc. The restoration of damaged muscles is especially effective, provided that the parameters of stimulating effects are chosen correctly. Therefore, in this work, it is proposed to use an information method for studying the neuromuscular system based on electromyography. The parameters of the stimulating effect do not always optimally correspond to a specific patient or a selected area of the body, which leads to insufficient effectiveness of therapeutic procedures, prolongation of rehabilitation. Elimination of shortcomings is possible due to the adjustment of the parameters of electrical stimuli depending on the data of myographic studies of a particular patient. Based on the data obtained by EMG, specific parameters of stimulating effects (electrical impulses) are selected, such as amplitude, frequency, duty cycle, etc., which makes it possible to implement a technical device for carrying out rehabilitation procedures. Therefore, an electromassage apparatus is proposed, built on the basis of a modern microcontroller, which allows, on the basis of EMG data, to change stimulating impulses of exposure in a fairly wide range, thereby realizing an individual approach to each patient and increasing the efficiency of therapeutic procedures. Keywords 1 Biomedical parameters, electromyostimulator, total electromyography, electromyogram, neuromuscular system, musculoskeletal system, time-frequency analysis 1. Introduction The effectiveness of the use of electrotherapy devices is largely based on the use of methods and means of diagnostic support, which would give In the modern world, the number of factors objective information about the patient's negatively affecting human health is becoming condition, contributing to the successful solution more and more.The human body ceases to have of the problem localization of zones of influence time to heal itself.All this requires a search for for electrostimulation, correct setting and new combinations of recovery methods., when achievement of treatment goals. medical devices are used in conjunction with drug In order to improve the quality and speed of methods, implementing various types of treatment, system development required, in which electrotherapy. III International Scientific And Practical Conference “Information Security And Information Technologies”, September 13–19, 2021, Odesa, Ukraine EMAIL: volodymyr.fedorchenko@nure.ua (A. 1); igor.prasol@nure.ua (A. 2); olha.yeroshenko@nure.ua(A. 3) ORCID: 0000-0001-7359-1460 (A. 1); 0000-0003-2537-7376 (A. 2); 0000-0001-6221-7158 (A. 3) ©️ 2021 Copyright for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0). CEUR Workshop Proceedings (CEUR-WS.org) automation will be provided, allowingprovide the most effective treatment result. The ultimate goal of creating an automated electrotherapy system is to develop modeling methodsand research of control systems and devices percutaneous electroneurostimulation, characterized by adaptation to changes in biological objects. The novelty is the development of a methodology for analyzing the functions of Figure 1: Dependence of the signal amplitude electrostimulating devices, which makes it and the excitation threshold of the possible to minimize negative effects during the neuromuscular structure( а) - muscle fiber, б) – stimulation procedure. muscle, 1) subthreshold stimulus, 2) threshold stimulus, 3) submaximal suprathreshold 2. Electrostimulation stimulus, 4) maximum suprathreshold stimulus) Electrical stimulation in this approach causes The dependence of the amplitude of muscle minimal changes in the treated area of the skinand contraction on the strength of the stimulus occurs nearby tissues, which allows to increase the according to the law of power relations: efficiency of the treatment process. • Each excitatory tissue has its own Skeletal muscle electrical stimulation, which functional reserve. are the basis of the musculoskeletal system, gives • Each excitatory tissue has its own a positive healing, preventive and training effects. functional boundary. During electrical stimulation of the With the help of electrical stimulation, you can neuromuscular system, a rational choice of modes temporarily change the muscle composition. In all is importantand a combination of tonic and kinetic cases, the strength of the electrical stimulation contractions, which significantly affect the current depends on its density per unit area of the increase in mass, development of strength, electrodes, resistance value on the electrode-skin increased excitability and muscle performance [1, section, excitability of those muscles, which are 2]. subject to stimulation and individual Electrical stimulation is successfully characteristics of the human body. The most combined with traditional drug therapy. To important factor that determines the shape of enhance metabolic and trophic processes, muscle muscle contraction is the frequency of irritation. tissue stimulation is performed using targeted Single muscle contractions are possible only with stimulation and contraction of a specific muscle a low frequency of irritation. At a high frequency group. of stimulation, the muscle contracts tetanically. An important property of neuromuscular For human skeletal muscles, the optimum structures when irritated by electric currents, the frequency of stimulation is different. The dependence of excitability on the rate of change optimum frequency of irritation also changes in the amplitude of the stimulating signal [1]. when the state of the body changes (fitness, time Depending on the signal amplitude and the of day, previous load, etc.). Pulse electric current excitation threshold of the neuromuscular used in electrostimulation has a wide variety of structure, the following electrostimulation modes characteristics (frequency, shape, pulse duration, are distinguished: subthreshold, threshold and character of the current, the ratio of the periods of suprathreshold(fig. 1) [3-5]. stimulation and pauses, etc.), which leads to a great variety of options for conducting electrical stimulation of the locomotor system. Optimal electrical stimulation is only possible if, when the repetition rate and shape of stimulating signals correspond to the physiological properties of neuromuscular structures. 3. Characteristics of muscle contraction The strength and speed of contraction are • Relative strength - the ratio of maximum important characteristics of a muscle. The strength to anatomical diameter. equations expressing these characteristics were The greatest work and power is achieved at empirically obtained by A. Hill and subsequently medium loads [4-6]. confirmed by the kinetic theory of muscle contraction (Deshcherevsky's model). 4. Electromyographic signal Hill's equation, which relates the strength and speed of muscle contraction, has the following processing method form [6-8]: For a qualitative and quantitative assessment (P+a)(v+b) = (P0+a)b = a(vmax+b), (1) of the state of the human neuromuscular system where v – muscle shortening rate; P – muscle using electromyogram (EMG) the information force or load applied to it; vmax - maximum speed method of time-frequency analysis based on of muscle shortening; P0 - strength developed by a spectrograms can be used (fig. 2, fig. 3) [6-12]. muscle in isometric contraction mode; a, b - This method is implemented on the basis of the constants. fast windowed Fourier transform. In this case, the The total power developed by the muscle is signal is divided into time intervals ("windows") determined by the formula: of short duration, within which it can be Ngen = (P+a)v = b(P0-P). (2) considered stationary. Time intervals are called The muscle efficiency remains constant (about quasi-stationary segments, and the approach to 40%) in the range of strength values from 0,2 P0 processing is analysis over short intervals [13-30]. to 0,8 P0. In the process of muscle contraction, a The original signal on the selected segment is certain amount of heat is released. This value is multiplied by the window function and undergoes a fast Fourier transform in accordance with the called heat production. expression: Heat production depends only on the change in STFT = ∫ [x(t)⋅ω∗ (t –τ)] ⋅ e−2jftπ dt, (4) muscle length and does not depend on the load. where x(t) – original signal, ω(t) – window Constants a and b have constant values for a given function, kτ – time shift amount, k – the ordinal muscle. Constant a has the dimension of force, a number of the window shift, f – frequency, t – and b - velocity. Constant b is highly temperature time, ω∗ (t) – complex conjugate window function dependent. The constant a is in the range of values [13-14]. from 0,25 P0 to 0,4 P0. Based on these data, the Next, we obtain a portion of the spectrogram maximum rate of contraction for a given muscle for the analyzed window by squaring the real part is estimated. [7-13]: (amplitude) of the windowed Fourier transform: vmax = b•( P0 / a). (3) X(t) = | STFT(τk,f)|2. (5) Muscle strength depends on the morphological To conduct a quantitative analysis of EMG properties and physiological state of the muscle: signals, it is necessary to calculate the following • The original muscle length (resting length). parameters of the time-frequency representation of the total EMG: lower and upper cutoff The more the muscle is stretched at rest, the frequency, median frequency, effective spectrum stronger the contraction (Frank-Starling law). width and a number of others [13-41]. • Muscle diameter or cross section. Allocate The average signal amplitude is also calculated two diameters: by the formula: - anatomical diameter - muscle cross 1 𝐴ср = ∑|𝐴 [𝑖 ]|, (6) section. 𝑁 - physiological diameter - the where A [i] - amplitude of the i-th sample of the perpendicular section of each muscle fiber. The registered signal, N – signal counts. larger the physiological section, the more strength The lower and upper cutoff frequencies the muscle has. determine the effective spectrum width, i.e., the There are two types of muscle strength: frequency range in which at least 90% of the signal power is concentrated [17-20]. The median • Absolute strength - the ratio of maximum is the frequency dividing the area under the energy strength to physiological diameter. spectral density curve into two equal parts [16]. Determination of frequency parameters is performed automatically based on the results of calculating the spectrogram of the EMG signal. For this, the value of the EMG signal energy in each cell of the spectrogram is calculated: 𝐸 [𝑖, 𝑗] = 𝐴[𝑖, 𝑗]2 , (7) [ ] where A i, j - the amplitude of the electromyogram in the i-th row and j-th column. Next, we determine the median frequencyfm . For this, a column with a serial number j is allocated, which corresponds to the spectral energy density of the signal at the j-th moment of time. Signal energy concentrated in effective Figure 3: Corresponding spectrogramof the spectrum widthEэфф [j] is more than 90%, muscle m. biceps brachii calculated by the formula: 𝐹 Let us represent the parameters of the EMG 𝐸эфф [𝑗] = 0,95 ∑ 𝐸 [𝑘, 𝑗]. (8) signal in the form of a certain finite set 𝑘=1 𝐴𝑚 = {𝑎𝑖 }(𝑖 = ̅̅̅̅̅̅ 1, 𝑚), (9) Lower cutoff frequencyfнj is determined from where А - the designation of this set; m – the condition: the difference between the sum of cardinality multitudes; аi – elements of the set. the elements of the column with indices from fнj The elements of the set can be amplitudes, 1 frequencies of the spectrum components, phase tо fmj and the value Eэфф [j] minimal modulo. shifts, etc. 2 Upper cutoff frequencyfвj is determined from Let us represent the parameters of stimulating the condition: the difference between the sum of influences also in the form of a finite set the elements of the column with indices from fmj 𝐵𝑛 = {𝑏𝑖 }(𝑖 = ̅̅̅̅̅ 1, 𝑛), (10) 1 where B - the designation of this set; n – tо fвj and the value Eэфф [j] minimal modulo. cardinality multitudes; bi – elements of the set. 2 These processing parameters make it possible The elements of the set can be the amplitude to fully assess the frequency content of the EMG and frequency of stimuli, the type of modulation, signal. modulation parameters, time intervals, etc. Thus, the task is to determine such a transformation ω, which provides an unambiguous display of the elements of the number А to the corresponding elements В 𝜔 𝐴 →𝐵 , (11) 𝑚 𝑛 EMG signal processing allows for ongoing monitoring the effectiveness of therapeutic effects due to the optimal selection parameters of stimulating effects. 5. Conclusions Quantitative analysis of the total Figure 2: Electromyogramof the muscle m. biceps electromyogram of the trained and untrained brachii muscle m. biceps brachii revealed the following patterns: – the average amplitude of the EMG signal for trained subjects reaches the highest values 345,62±148,10 μV, for the untrained equals 189,27±84,00 μV; – the median frequency is characterized by the "KhPI", № 13 (1338). (2019)165–175.doi: lowest values 111,44±27,62 Hz for trained 10.20998/2411-0558.2019.13.15 subjects and 123,00±30,07 Hz for untrained; [3] P. P. Pestrikov, T.V. Pestrikova, Measuring – the upper cutoff frequency for trained system for recording signals from surface subjects is 409,07±69,91 Hz and electromyography of forearm 446,90±66,22 Hz for untrained; muscles,Electronic scientific publication "Scientific notes of PNU". Volume 10. No. – the effective spectrum width for trained 2. (2019) 173–180. subjects is 382,09±71,42 Hz and [4] O. Yeroshenko, I. Prasol, O. Datsok, 415,92±65,35 Hz for untrained. Simulationofanelectromyographicsignalcon Comparative analysis of the calculated verterforadaptiveelectricalstimulationtasks, parameters for trained and untrained subjects: The current state of research and technology indicators of the upper cutoff frequency, median in industry. № 1 (15). (2021) 113–119. doi: frequency and effective spectrum width for 10.30837/ITSSI.2021.15.113 untrained subjects exceed the corresponding [5] S. S. Nikitin, Electromyographic stages of values for trained subjects. the denervation-reinnervation process in The proposed amplitude-frequency criterion neuromuscular diseases: the need for allows one to take into account basic parameters revision, Neuromuscular diseases. Moscow. of non-stationary bioelectric signal (amplitude №2. (2015) 16–24. and frequency) and thus to carry out quick and [6] C. J.De Luca, The use of surface electromyography in biomechanics, Journal effective express diagnostics of the functional of Applied Biomechanics. № 13 (2). (1997). state of the neuromuscular system using [7] S. H.Roy, G. DeLuca, S.Cheng, automated complexes of time-frequency A.Johansson, L. D.Gilmore, C. J.De Luca, processing of EMG signals. Electro-Mechanical stability of surface EMG Thus, carrying out qualitative and quantitative sensors, Medical and biological engineering analyzes the structure of an EMG signal that is and computing. № 45. (2007). unsteady in natureand the dynamics of its [8] M.Voelker Implantable EMG measuring parameters in the process of muscle contraction is system, AMA Conferences. (2015). performed based on the spectrogram, realizing [9] O. Yeroshenko, I. Prasol, O. Trubitsyn, and graphical visualization of the amplitude, L. Rebezyuk, Organization of a Wireless frequency and time components of the biomedical System for Individual Biomedical Data signal in real time. Consequently, specific Collection, International Journal of parameters of stimulating effects can be selected Innovative Technology and Exploring based on the data of the EMG signal, which makes Engineering, vol. 9, no. 4, (2020)2418– it possible to implement an effective technical 2421.doi: 10.35940/ijitee.D1870.029420 device for carrying out individual therapeutic [10] A. N. Osipov, S. K. Dick, K. G. Senkovsky, procedures. Complex biotechnical feedback in electrostimulation systems, Moscow: 6. References Medical technology, № 6. (2007) 27– 29. [11] K. Jermey, Atlas of Musculoskeletal [1] О. А. Yeroshenko, I. V. Prasol, Anatomy, AST Publishing House. (2008) V. V. Semenets, About building a system of 382 p. muscle electrical stimulation for cadets,The [12] S.H.Roy, G.Luca De, S.Cheng, A.Johansson, use of information technology in the training L.D. Gilmore, C.J.Luca De, Electro- and operation of law enforcement: materials Mechanical stability of surface EMG International. scientific-practical conf. Mar sensors, Medical and biological engineering 14-15 2018 Kharkiv: NANGU (2018) 120– and computing. Vol. 45. (2007). 122. [13] М. М. Mezhennaya, Time-frequency [2] О. M. Datsok, І. V. Prasol, О.А. Yeroshenko, analysis of the total electromyogram in the Construction of a biotechnical system of qualitative and quantitative assessment of the muscular electrical stimulation,Bulletin of functional state of the human neuromuscular NTU "KhPI". Series: system. Biomedical radioelectronics. № 2. Informaticsandmodeling. Kharkiv: NTU (2012) 3-11. [14] S. G. Nikolaev, Workshop on clinical medicine (2015) 185– electromyography, Ivanovo.(2001) 264 p. 197.doi:10.17691/stm2015.7.2.22. [15] B. M. Gekht, Theoretical and clinical [26] H. Kawamoto, Y. Sankai, Power assist electromyography. (1990) 229 p. methodbased on phase sequence and muscle [16] A. V. Sidorenko, V. I. Khodulev, A. P. force conditionfor HAL, Adv Robotic Selitskiy, Nonlinear analysis of (2005)717–734.doi: electromyograms, Biomedical technologies 10.1163/1568553054455103. and electronics. №11. (200) 53–59. [27] D.P. Ferris, G.S. Sawicki, M.A. Daley, A [17] M. M.Mezhennaya, Choice of parameters of physiologist’sperspective on robotic time-frequency processing of exoskeletons for human locomotion,Int J HR electromyograms of the neuromuscular (2007) 507–528.doi: apparatus, RT-2010: materials of the 6th Int. 10.1142/s0219843607001138 youth scientific-tech. conf. Sevastopol: [28] K.E. Gordon, M. Wu, J.H. Kahn, B.D. SevNTU. (2010) 464 p. Schmit, Feedbackand feedforward [18] I. Perova, Ye. Bodyanskiy, Adaptive Human locomotor adaptations to ankle-foot load Machine Interaction Approach for Feature inpeople with incomplete spinal cord injury, Selection-Extraction Task in Medical Data J Neurophysiol (2010)1325–1338.Doi: Mining, International Journal of Computing, 10.1152/jn.00604.2009. no. 17(2). (2018) 113-119. [29] C.K. Battye, A. Nightengale, J. Whillis The [19] M. Akay, Time-frequency representationsof use of myoelectric current in the operation of signals, Detection and estimation methods prostheses, J Bone JointSurg Br 37-B(3). forbiomedical signals. San Diego: Academic (1995) 506–510. Press. (1996) 111–152. [30] F.R. Finley, R.W. Wirta,Myocoder studies of [20] M. Hosokawa, Time-Frequency Analysis of multiplemyopotential response, Arch Phys Electronystagmogram Signals in Patients Med Rehabil 48(11).(1967) 598–601. with Congenital Nystagmus, Japanese [31] B.Peerdeman, D.Boere, H.Witteveen, Ophthalmological Society. Vol. 48. (2004) R.Huis in`tVeld, H.Hermens, i S.Stramigiol, 262–267 H.Rietman, P.Veltink,S. Misra,Myoelectric [21] J. Kaipio, Simulation and Estimation forearm prostheses: state of the art froma ofNonstationary EEG, Natural and user-centered perspective, J Rehabil Res Dev Environmental Sciences. Vol. 40. (1996) 48(6).(2011)719.doi: 110. 10.1682/jrrd.2010.08.0161. [22] Z.Y Lin, D.Z Chen, Time-frequency [32] M. Aminoff Electromyography in clinical representation ofthe electrogastrogram – practice,Addison-Wesley (1978). application of the exponential distributions, [33] J.M. Wakeling Spectral properties of the IEEE TransBiomed Eng. Vol. 41. (1994) surface EMGcan characterize motor unit 267–275. recruitment strategies, J ApplPhysiol; [23] Rohtash Dhiman et al. Detecting the useful 105(5).(2008) 1676–1677. electromyogram signals–extracting, [34] C. Fleischer, A. Wege, K. Kondak, conditioning andclassification, IJCSE. – G.Hommel, Application of EMG signals for Aug.–Sep. 2011. V. 2. № 4. (2011) 634–637. controlling exoskeletonrobots, Biomed Tech [24] A.S.Borgul, A.A.Margun, K.A.Zimenko, 51(5–6). (2006)314–319.doc: A.SKremlev., A.Y. Krasnov Intuitive 10.1515/BMT.2006.063. Control for Robotic Rehabilitation Devices [35] D. Farina, L. Mesin, S. Marina, R.A. by Human-Machine Interface with EMG and Merletti, SurfaceEMG generation model EEG Signals, 17th international with multilayer cylindrical descriptionof the conferenceon Methods and Models in volume conductor, IEEE Trans Biomed Eng Automation and Robotics (MMAR 2012). 51(3).(2004) 415–426.doi: Proceedings. Międzyzdroje: IEEEXplore 10.1109/TBME.2003.820998. digital library.(2012) 308–311. [36] H.J. Hermens, B. Freriks, C. Disselhorst- [25] A.A. Vorobyev, A.V. Petrukhin, O.A. Klug, G. Rau,Development of Zasypkina,P.S. Krivonozhkina, A.M. recommendations for SEMG sensors Pozdnyakov, Exoskeleton as a newmeans in andsensor placement procedures, J habilitation and rehabilitation of invalids Electromyogr Kinesiol 10(5).(2000)361– (review),Sovremennye tehnologii v 374.doi: 10.1016/S1050-6411(00)00027-4. [37] F. Sylos-Labini, V La Scaleia, A. d’Avella, I. Pisotta,F. Tamburella, G. Scivoletto, M. Molinari, S. Wang, L. Wang,E. van Asseldonk, H. van der Kooij, T. Hoellinger, G. Cheron,F. Thorsteinsson, M. Ilzkovitz, J.Gancet, R.Hauffe, F.Zanov,F.Lacquaniti, Y.P. Ivanenko,EMG patterns during assistedwalking in the exoskeleton, Front Hum Neurosci 8.(2014)423.doi: 10.3389/fnhum.2014.00423. [38] R.Merletti, M.Aventaggiato, A.Botter, A.Holobar,H.Marateb, T. Vieira,Advances in surface EMG: recentprogress in detection and processing techniques, Crit RevBiomed Eng 38(4).(2011) 305–345.doi: 10.1615/CritRevBiomedEng.v38.i4.10. [39] D. Farina, C. Cescon, Concentric-ring electrode systemfor noninvasive detection of single motor unit activity, IEEETrans Biomed Eng 48(11).(2001) 1326–1334.doi: 10.1109/10.959328. [40] J.L. Nielsen, S.Holmgaard, N.Jiang, K.Englehart,D.Farina, P. Parker,Enhanced EMG signal processing forsimultaneous and proportional myoelectric control, Conf ProcIEEE Eng Med Biol Soc (2009) 4335– 4338. doi: 10.1109/IEMBS.2009.5332745. [41] D.P.Ferris, C.L. Lewis,Robotic lower limb exoskeletonsusing proportional myoelectric control, Conf Proc IEEEEng Med Biol Soc (2009) 2119–2124.doi: 10.1109/IEMBS.2009.5333984.