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<article xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Systems for Critical Medical Conditions in Pregnancy</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Care⋆</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Patience U. Usip</string-name>
          <email>patienceusip@uniiuyo.edu.ng</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Agnes Udo</string-name>
          <email>agnesgudo247@gmail.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Funebi F. Ijebu</string-name>
          <email>ijebufrancis@uniuyo.edu.ng</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Sanju Tiwari</string-name>
          <email>sanju.tiwari.2007@gmail.com</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>1Computer Science Department, University of Uyo</institution>
          ,
          <addr-line>Uyo</addr-line>
          ,
          <country country="NG">Nigeria</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Universidad Autonoma de Tamaulipas</institution>
          ,
          <country country="MX">Mexico</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>AMedical conditions require proper attention as some of them especially those occurring in women that are expecting pregnancy require proper care. Although pregnancy exposes them to several critical health conditions, most of these conditions were actually in existence before pregnancy with their causes traced back to poor nutrition resulting from food intake. However, there have been a good number of food recommendation systems in existence with few of them being context-aware. This work is aimed at performing a critical review of the food recommender systems that considers medical conditions and design the food ontology for critical medical conditions that adopts the pathology test results of patients in caring for the existing medical conditions such as pregnancy. Focus of the framework is on deploying a multilingual ontology-based approach in addition to other required approaches for recommendations. This work also introduces the addition of uncooked food in the food ontology for recommendations. The proposed food ontology for critical medical conditions considers the required nutrients based on the combination of several factors including the pathology test results, location/language, medical conditions and user preferences. The use of this food ontology framework for food recommender is reliable due to the additional factors.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>recommendation systems use algorithms including the collaborative filtering, content-based
and hybrid approaches. Context-Aware Recommendation (CAR) is a recent approach said to
generate better recommendations based on the specific contextual situation of the user. CARs
use several approaches to incorporate contextual information for the users in the
recommendation process and then use such approaches for diferent applications. The representation
of these knowledge for context-aware recommendations is very necessary. Hence, the choice
of ontologies as representation tools for semantic web reasoning of the proposed food
recommender system.</p>
      <p>
        Ontology is best known for defining the concepts and relationships used to describe and
represent an area of concern with the specific role of facilitating data organization and integration in
the semantic web [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. Ontologies are suitably considered here due to its crucial role in enabling
automatic knowledge processing, sharing, and reuse among various applications. The use of
ontologies and other AI techniques are reported by many potential research studies [
        <xref ref-type="bibr" rid="ref2 ref3 ref4">2, 3, 4</xref>
        ].
Another application domain with high demand for context-based recommendation is the food
and health domain with a particular task of providing care for expectant mother and the unborn
baby (pregnancy) regarding what should be eaten. Making decisions about what to eat, when
to eat and even the proportion of food intake has become major problem in our everyday lives,
particularly the expectant mothers, due to a wide variety of ingredients, cultures, personal
tastes and individual medical conditions has made choosing the right food at the right time to
be as a very dificult task. Today, many diseases that were previously thought as hereditary are
now seen to be connected to biological dys-function related to nutrition.
      </p>
      <p>Already existing food recommender systems mostly focused on meals (cooked food) and users’
preferences without considering uncooked food and pathology test of users for accurate
breakdown of the nutritional state of the user. Among many factors for healthy living, right food
consumption is one of the major factors, specifically, for people sufering from critical health
ailments such as over-weight, under-weight, heart disease, cancer, diabetes, allergies, obesity,
which may significantly lead to many other complications in pregnancy such as birth defects,
premature birth, miscarriage, stillbirth and infertility. Complications in pregnancy can be life
threatening (critical), most common, minor, rare, early and chronic. Although, certain medical
conditions may complicate a pregnancy, with proper care, most women can enjoy a healthy
pregnancy even with her health challenges. Various studies portray that inappropriate and
insuficient intake of food are the major reasons of various health issues and diseases
(WHO/UNISEF, 2001).</p>
      <p>Most of the critical health conditions occur due to the excess and deficiency of food element.
Some of the key elements of food include carbohydrate, calcium, iron, protein and vitamins and
the consumption of balanced diet can normalize some of the medical conditions. Addressing
the problem of selecting what and how to eat can promote healthy living and decrease usage of
unhealthy food ingredients or compounds such as oxidants. Healthy eating is possible only
when you ensure that your body is getting the right food elements in the right quantity that
it requires. Therefore, it is essential to know about the food nutrition to be sure of what is
consumed into the body. These food elements categorically include carbonaceous (starch, sugar,
fats), nitrogenous(albumen) and inorganic substances (minerals).</p>
      <p>The requirement of food changes over time, with respect to the stage of life that we are in, for
example while a child requires food to grow and develop, adults need it more for the energy
required to function daily. In addition to that, food is also required so as to repair the various
parts of the body that are worn away, or those that have to be discarded due to wear and tear
caused by critical health conditions. Therefore, we need to continuously replenish our body
with a variety of elements present in food and drink. Pathology test is the major mode of
examination that ofers the status of these key elements.</p>
      <p>
        To get appropriate food intake to improve overall well-being, smart food recommender systems
will ofer prevalent recommendation for healthier food choices [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ]. This work is aimed at
carrying out a critical review of food recommendation systems that consider medical conditions
and giving the design of a context aware food recommender framework for medical conditions
and pregnancy care. Its focus is on providing an ontology-based model for classification and
recommendation of food (cooked and uncooked) for users with critical health conditions in the
right proportion for consumption. This work will bring an improvement to the challenge of
an existing system by directly recommending right food (cooked and uncooked), nutritional
elements and the proportion of food consumption especially for critical health conditions based
on user’s pathological reports
The rest of the paper is organized as follows. Section 2 presents the critical review on related
works while the methodologies and the data collection adopted for the design of the system
are described in section 3. Section 4 presents a detailed food ontology to include the uncooked
brand of food with the required proportion of the nutritional elements for pregnant women
with medical conditions.
2. Related Literature about Recommendation Algorithms
2.1. Recommendation Algorithms
The major and most common algorithms used in recommendation systems are discussed as
follows. Collaborative filtering is basically an algorithm used in the recommendation system
that basically makes the use of similarities between the items and users in order to provide the
right recommendations. This means this type of algorithm can provide a recommendation to
user A depending on the interest of a similar user B. What makes collaborative filtering diferent
is the fact the past user-item interaction is enough for the predictions to be made for similar
users.
      </p>
      <p>Content-based recommendation, on the other hand, solely depends on the choice of the users
themselves, and the recommendations are made based on the items or products the users like
based on their previous feedback or actions. The content-based recommendations shown in
Figure 3 are less problematic for the new users as the items can be described by their
characteristics or content, and thus relevant recommendations can be made for the new entities.
The hybrid approach of recommendations combines collaborative and content-based
recommendations. In a system, first the content recommender takes place as no user data is present,
then after using the system the user preferences with similar users are established. These kinds
of approaches are said to have provided better and accurate recommendations. Netflix uses a
hybrid approach of recommendations because it compares the watching habits of similar users
and also ofer movies that share the characteristics with all those films which the user has rated
high.</p>
      <p>The earliest recommendation system, called Tapestry filters, use information by collaborative
ifltering system. Collaborative recommendation system is the most famous and commonly
used one. The system analyses the preferences from the set of users within the system. It finds
out the set of users with similar characteristics and takes this relevance as evidence to induct
the potential preferences of the users. Besides recommending the interested information to
the users, this research is expected to recommend the information that may arouse the users’
potential demands based on users’ culture and pathology test.</p>
      <p>Various studies portray that inappropriate and insuficient intake of food are the major reasons
of various health issues and diseases. A study conducted by World Health Organization (WHO)
estimate that about 30% of the total population of the world is sufering from various diseases,
60% deaths each year in children are related to malnutrition and about 9% of heart attack
deaths. Moreover, many children are sufering from Vitamin-A deficiency, 200 billion people are
sufering from iron deficiency (anemia) and a lot of people are sufering from iodine deficiency
(WHO/UNISEF, 2001).</p>
      <p>
        Several works proposed diferent recommendation systems related to food. These systems can
be categorized as:
(a) food recommendation systems [
        <xref ref-type="bibr" rid="ref7 ref8">7, 8</xref>
        ]
(b) menu recommendations [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ]
(c) diet plan recommendations[
        <xref ref-type="bibr" rid="ref10">10</xref>
        ]
(d) health recommendations for diferent diseases like diabetes and cardiovascular [
        <xref ref-type="bibr" rid="ref11 ref12">11, 12</xref>
        ]
(e) recipe recommendations [13, 14]
The above mentioned systems provide recommendations to either some specific disease or
balance the diet without considering information about any disease or nutrition deficiency in the
body. For instance, in[
        <xref ref-type="bibr" rid="ref7">7</xref>
        ] a food recommendation system is proposed for diabetic patients that
used K-mean clustering and Self-Organizing Map for clustering analysis of food. The system
recommends various foods for diabetic patients without considering the disease level that may
lfuctuate frequently in diferent situations of the patient and the food recommendations may
also vary accordingly.
      </p>
      <p>
        Similarly, the authors in [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ], do not consider the nutrition factors that have significant
importance for a balanced diet recommendation. Tags and latent factor are used for android-based
food recommender system [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]. The system recommends personalized recipe to the user based
on tags and ratings provided in user preferences. The proposed system used latent feature
vectors and matrix factorization in their algorithm. Prediction accuracy is achieved by use of
tags which closely match the recommendations with users’ preferences. However, the authors
do not consider the nutrition factors in order to balance the diet of the user according to his
needs.
      </p>
      <p>Content based food recommender system [13] is proposed which recommend food recipes
according to the preferences already given by the user. The preferred recipes of the user are
fragmented into ingredients which are assigned ratings according to the stored users’
preferences. The recipes with the matching ingredient are recommended. The authors do not consider
the nutrition factors and the balance in the diet. Moreover, chances of identical recommendation
are also present because the preference of the user may not change on daily basis.
In [15], knowledge based dietary nutrition recommendation system is proposed for obesity. The
recommendations include dietary nutrition and diet menus for individuals using collaborative
ifltering technique. An application for mobile users is also developed in order to recommend
the dietary and menus to the users. Similarly, a food recommender system is proposed in [16]
for patients in care facilities. The application is designed for caregivers in the care facilities in
order to ofer the food according to the patient preferences.</p>
      <p>
        Majority of these recommendation systems extract users’ preferences from diferent sources like
users’ ratings [
        <xref ref-type="bibr" rid="ref5">17, 5</xref>
        ], recipe choices [18, 19] and browsing history1 [20] ,[21, 22] . For instance,
in [19] a recipe recommendation system is proposed using social navigation system. The social
navigation system extracts users’ choices of recipes and in return recommends the recipes.
Similarly, in[22], a recipe recommendation system is proposed that is capable of learning similarity
measure of recipes using crowd card-sorting. The above-mentioned recommendation systems
lack in solving a common problem known as cold start problem. All these systems must wait
for the users to enter enough data for the efective recommendations[ 23].
      </p>
      <p>Some of the commercial applications ofer users for a quick survey in order to get users
preferences in a short time. For instance, the survey used by [24] is specifically designed to match the
lifestyle of the user i.e., healthy, sportsman, pregnant, etc. The survey also attempts to avoid
various foods which do not match the user’s lifestyle. Similarly, a questionnaire is used by
[25] through which a user answers diferent questions about his/her lifestyle, food preferences,
nutrient intake, and habits. The system once extracts all the basic information is then able to
recommend diferent meals for daily and weekly basis.</p>
      <p>This work presents an ontology-based multi-lingual food recommendation system that will
specifically deal with the pathological tests results. Our system considers diseases related to
pathological reports, most common nutrition factors in recommending the food items to the
users and the proportion of the food intake. For this purpose, we will use a database of 400
pathological test reports to categorize various diseases that occur due to the changes from the
normal ranges of compounds/parameters.
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Addressing the problem of selecting what and how to eat can promote healthy living and
decrease usage of unhealthy food ingredients or compounds such as oxidants. To get appropriate
food intake to improve overall well-being, smart food recommender systems will ofer prevalent
recommendation for healthier food choices [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ]. The mode of examination to ofer the key
element is pathology test.
      </p>
      <p>The following categories of knowledge (concepts and relations) were obtained from literatures
and adopted in this work. 1. Nutritional Elements: The key nutritional elements of food such
as carbohydrate, calcium, iron, protein and vitamins. 2. Categories of Food Elements: They
are classified as carbonaceous (starch, sugar, fats), nitrogenous(albumen) and inorganic
substances (minerals). 3. Complications in Pregnancy: Birth defects, Premature death, miscarriage,
stillbirth, infertility, Preeclampsia, Preterm Labor, Gestational Diabetes, 4. Classes of
Complications in Pregnancy: life threatening (critical), most common, minor, rare, early, chronic 5.
Critical medical conditions: over-weight, under-weight, heart disease, cancer, diabetes, allergies,
obesity, pregnancy 6. Food: food can be cooked(meal) and uncooked 7. Pathology test: Can
be blood tests, urine tests, stools (faeces) and bodily tissues 8. Specialisations in pathology:
chemical, haematology, anatomical, Cytopathology, medical microbiology (bacteria, viruses,
fungi, parasites), immunopathology, genetic, forensic pathology, general, clinical In addition
to that, food is also required so as to repair the various parts of the body that are worn away,
or those that have to be discarded due to wear and tear caused by critical health conditions.
Therefore, we need to continuously replenish our body with a variety of elements present in
food and drink. Healthy eating is possible only when you ensure that your body is getting the
right food elements in the right quantity that it requires. Therefore, it is essential to know about
the food nutrition to be sure of what you consumed into the body.
4. Food Ontology for Critical Medical Conditions
The Meal Recommender System will recommend list of desired meals based on the health
condition of the User. The Ontology classifies the meal with concentration on those suitable for
patients with critical health conditions in both Veg and Non-Veg classes and at specific times
for the meal (Breakfast, Lunch and Dinner). The ontology design is as described in Figure 1.</p>
      <p>The presence of the location or language which every patient has and every menu for all
meals are based on the location/language introduce the concept of multilinguality in the food
recommendation process. The use of the pathology test results for each patients unfolds the
nutrition deficiency of these patients, their susceptibility to some critical medical conditions
and the need to recommend food based on their nutritional values.</p>
      <p>The concepts and relationships used to describe and represent the domain of discourse are shown
in the ontology diagram with all the linkages to all necessary domain data/information. The role
of ontologies in Semantic Web is to facilitate data organization and integration. The concepts
include: patients, pathology test results, critical medical conditions, balanced diet informed by
nutrition contained in food. The recommendations will be based on the language/location of
the patient. Other sub-concepts are as contained in the food ontology without the linked data.</p>
    </sec>
    <sec id="sec-2">
      <title>5. Conclusion</title>
      <p>This integrated data (known as Linked Data) can be used for reasoning or simply querying is
the main strength of the Semantic Web as it introduces various levels of complexities to the
food ontology. Ontologies can play a crucial role in enabling automatic knowledge processing,
sharing, and reuse among applications. Reasoning with the food ontology in multilinguality
is therefore an interesting research task that needs to be carried out and doing this requires a
context-aware recommender framework.
factors: Us preventive services task force recommendation statement, Annals of internal
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