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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Jaén, Spain
* Corresponding author.
$ aduque@lsi.uned.es (A. Duque); lurdes@lsi.uned.es (L. Araujo); juaner@lsi.uned.es (J. Martinez-Romo);
gildo.fabregat@gmail.com (H. Fabregat)</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>LSI_UNED at ClinAIS 2023: Transformer Models for Section Identification in Spanish Medical Reports</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Andres Duque</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Lourdes Araujo</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Juan Martinez-Romo</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Hermenegildo Fabregat</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Avature Machine Learning</institution>
          ,
          <country country="ES">Spain</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>IMIENS: Instituto Mixto de Investigación, Escuela Nacional de Sanidad</institution>
          ,
          <addr-line>Monforte de Lemos 5, Madrid 28019</addr-line>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>NLP &amp; IR Group, Dpto. Lenguajes y Sistemas Informáticos, Universidad Nacional de Educación a Distancia (UNED)</institution>
          ,
          <addr-line>Juan del Rosal 16, Madrid 28040</addr-line>
          ,
          <country country="ES">Spain</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2023</year>
      </pub-date>
      <volume>000</volume>
      <fpage>0</fpage>
      <lpage>0002</lpage>
      <abstract>
        <p>This paper presents our participation in the ClinAIS task of the IberLEF 2023 shared evaluation campaign, devoted to the automatic section identification in medical reports written in the Spanish language. Our proposal is based on the use of Transformer-based models to perform a token classification task. In this task, we use a Named Entity Recognition-like annotation of the provided training dataset for jointly detecting the boundaries of each section in the report, and classifying the detected section. Two diferent pre-trained models are tested and their hyperparameters are explored, and two annotation schemes are tested in our experiments. Our approach achieves the second best results in the task, thus supporting the use of this type of techniques for performing clinical section identification.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;Clinical section identification</kwd>
        <kwd>Transformer models</kwd>
        <kwd>annotation schemes</kwd>
        <kwd>Spanish language</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Clinical narratives can be found in diferent types of unstructured medical documents such as
Electronic Health Records (EHR) or Electronic Discharge Summaries (EDS). In these documents,
doctors and practitioners gather many diferent aspects of patient information related to a clinical
case, such as past and present medical history, diagnoses, treatments or laboratory results [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ].
Although healthcare systems usually provide guidelines for writing clinical documents, most
of the information contained in these documents can be considered unstructured or poorly
structured. However, medical entities and expressions usually ofer diferent information
depending on the section they are found within the medical document. Therefore, and given
the vast amount of this kind of data within the medical domain, the development of automatic
systems performing section identification may help improving a variety of downstream tasks
in the field such as Named Entity Recognition (NER) [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ], temporal relation extraction [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ] or
ICD-10 coding [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ].
      </p>
      <p>
        In this paper we present our participation in the ClinAIS task of the IberLEF 2023 shared
evaluation campaign [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ], to be held as part of the XXXIX conference of the Spanish Society for
Natural Language Processing (SEPLN 2023). Systems participating in the ClinAIS task must
automatically identify diferent medical sections in unstructured clinical documents written in
the Spanish language. The proposed system employs Transformer-based architectures using
diferent context windows for identifying those sections, through a Named Entity Recognition
(NER)-like methodology with diferent annotation schemes. For this purpose, we consider
tokenized texts and define the diferent labels or NER tags indicating the starting token of each
particular section. Then, we train the diferent selected models for recognizing those labels and
hence the starting point of each identified section.
      </p>
      <p>The rest of the paper is structured as follows: Section 2 is devoted to exploring existing
systems performing automatic medical section identification. The particular task addressed in
this work, together with the available dataset and evaluation metrics, are described in Section 3.
The developed system is described in Section 4 and the obtained results in Section 5. Finally,
Section 6 ofers some conclusions regarding this research and possible lines of work to be
followed in the future.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Related Work</title>
      <p>
        The automatic identification of sections in clinical documents has been normally addressed
through three main diferent techniques: rule-based systems, machine learning systems and a
combination of both [6]. Among the rule-based methods, some previous works make use of exact
matching techniques for determining the boundaries (beginning and end of a section) [7, 8],
although regular expressions allow the systems to generalize the detection of indicators of these
boundaries [
        <xref ref-type="bibr" rid="ref4">4, 9</xref>
        ]. Also, probabilistic methods can be found in the literature complementing these
previous approaches by taking advantage of clinical corpora from which specific probabilistic
knowledge can be modeled and then applied to new medical reports for detecting the desired
sections [10, 11].
      </p>
      <p>Regarding machine learning methods, classical methods such as logistic regression can be
found performing section identification at sentence level [ 12], while Conditional Random Fields
(CRFs) and Support Vector Machines (SVMs) usually show good performance in this kind of
tasks [13, 14]. However, in the last few years, the rise of deep learning models has produced
important advances in the field. Section detection in medical dictations is addressed in [ 15]
through the use of LSTMs [16] as a binary classification task at token level, this is, classifying
each token as positive if it indicates the beginning of a section and negative otherwise. Recurrent
Neural Networks (RNNs) and BERT [17] are used in [18] for classifying sections in Electronic
Health Records (EHRs), including transfer learning techniques in order to overcome the lack of
training data.</p>
    </sec>
    <sec id="sec-3">
      <title>3. The ClinAIS Task</title>
      <p>The ClinAIS task is part of the shared evaluation campaign IberLEF 2023 and aims to develop
systems for the automatic identification of sections within medical reports written in Spanish.
The following seven possible sections are defined within the reports, which may or may not
occur and may appear more than once in the same clinical report: “Present Illness”, “Derived
from/to”, “Past Medical History”, “Family History”, “Exploration”, “Treatment” and “Evolution”.</p>
      <p>Therefore, the main objective of a system participating in the task is to detect the boundaries
of the sections (i.e., the start and end tokens) as well as to classify the correct section. Additional
information about the task can be found in [19].</p>
      <sec id="sec-3-1">
        <title>3.1. Dataset</title>
        <p>The dataset provided by the organizers is a subset of the CodiEsp dataset, originally used in
the CLEF eHealth 2020 task [20]. Specifically, the corpus used for the ClinAIS task is a revised
version of the dataset presented in [21] and contains 1,038 clinical reports and is divided into
training (781 reports), development (127 reports), and test (130 reports) splits. Each of these
datasets consists of a JSON file that stores a set of clinical reports, both in raw text format and
tokenized text format, so participants do not need to perform text tokenization. Therefore, each
of the tokens within a clinical report may or may not be the beginning of one of the sections
to be identified. The average length of the reports is 374.04 tokens, while each report has an
average of 6.94 sections (4.38 unique sections).</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Evaluation Metrics</title>
        <p>The metric proposed in the task to evaluate participating systems is called B2 and takes into
account operations such as additions, deletions, substitutions and n-wise transpositions for
evaluating the diferences between the detected sections and the Gold Standard sections. Additions
and deletions can be considered complete errors, as they represent either detected sections that
do not exist in the Gold Standard or undetected sections that are present in the Gold Standard.
Substitutions occur when the boundaries of a section are correctly detected, but the section
type is classified incorrectly. Finally, n-wise transpositions refer to situations in which a section
is correctly detected, but the predicted boundaries are displaced  words with respect to the
Gold Standard.</p>
        <p>With all this information, diferent weights are assigned to each operation for designing the
ifnal formula. This formula assigns a score to the system on each of the considered medical
reports. The final evaluation of the system is computed by performing a weighted average of
all the reports in the test dataset, using the number of sections in the Gold Standard of each
report as a means of assigning weights. More information about the specifics of the evaluation
metric can be found in [19].</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Proposed System</title>
      <p>The system developed in this research mainly focuses on the use of pre-trained models based on
the Transformer architecture [22]. The addressed task is modeled as a Named Entity Recognition
task, hence the main objective of the developed models will be to correctly identify the label of
each token within a medical report. This way, we will be able to subsequently determine the
start and end token of each section, this is, the section’s boundaries. For this purpose, a token
classification layer is added on top of the pre-trained models in order to fine-tune it with the
available training dataset.</p>
      <sec id="sec-4-1">
        <title>4.1. Transformer Models</title>
        <p>Two diferent Transformer-based pre-trained models are used in this research: the first one
is a RoBERTa [23] model pre-trained with clinical and biomedical information from diferent
sources, written in the Spanish language [24]. However, the main limitation of this model is that
the maximum size of the documents that can be processed is 512 tokens, while the task dataset
presents longer documents. In order to get around this limitation, we divide the documents
into smaller chunks by performing a sentence-based splitting while setting a minimum context
size of 128 or 256 tokens. This way we ensure that these new instances to be processed by the
model do not exceed the 512-token limitation, while maintaining a minimum size that avoids
losing important information for performing token classification.</p>
        <p>The second Transformer-based model used in this work is a Longformer architecture [25]
also pre-trained with biomedical and clinical information written in the Spanish language [26].
The main advantage of this model is the extension of the maximum document size to 4096
tokens, which in this case allows us to process all the documents in the task dataset without the
need of splitting them into smaller instances.</p>
        <p>Models have been trained during 10 and 100 epochs in order to determine whether overfitting
issues can afect the final performance of the trained models, as well as the impact of this epoch
size on the final results. A batch size of 4 has been used for all the experiments, with a learning
rate of 5 × 10− 5. The AdamW optimizer with a weight decay of 10− 5 has been also used in all
the proposed experiments. Finally, categorical cross-entropy is used as the loss function for
ifne-tuning the models.</p>
      </sec>
      <sec id="sec-4-2">
        <title>4.2. Annotation Schemes</title>
        <p>We propose two diferent annotation schemes for addressing this task as a Named Entity
Recognition task, this is, a token classification task. The first scheme, denoted
“SimpleNER”, defines a particular label for a token indicating the beginning of a new section within
the document, and a label “O” for the rest of the tokens in the document. Hence a
total of 8 diferent labels can be assigned to each token: “O”, “PRESENT_ILLNESS”,
“DERIVED_FROM/TO”, “PAST_MEDICAL_HISTORY”, “FAMILY_HISTORY”, “EXPLORATION”,
“TREATMENT” and“EVOLUTION”. Then, each test instance will be post-processed in order to
determine the boundaries of each section. A section will start each time a token classified with
a label diferent from “O” is found. The following “O” tokens will be considered to be within the
found section, until a new label diferent from “O” is found, except if this new label indicates
the same section that was being considered.</p>
        <p>The second annotation scheme, denoted “Full-NER”, performs a slightly more sophisticated
labeling of the tokens within the training instances. In this case, we diferentiate the starting,
inner and ending tokens of each section. Hence, for each section “S” we define labels
“BS” (starting token of section “S”), “I-S” (inner token of section “S”) and “L-S” (last token of
section “S”). A total of 21 diferent labels are then defined for this scheme. Some additional
post-processing rules are then added in this case for performing the final annotation of each
test instance: we consider that a new section begins whenever a label belonging to a diferent
section is found, regardless of whether it is a starting, inner or last label. Also, we consider that
a new section must contain at least three tokens, hence if a section with only one or two tokens
is found, it is not classified, and the tokens are considered to belong to the previous section.
These post-processing rules have been designed after manual observation of the development
dataset.</p>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>5. Results</title>
      <p>In this section we will discuss the main results obtained by the proposed system on the test
dataset of the ClinAIS task, as well as a comparative among the diferent systems participating
in the task.</p>
      <p>Up to 5 runs could be submitted for evaluation in the task. Table 1 shows the characteristics of
the diferent runs submitted by our team: Transformer-based model employed in the experiment,
context size, number of epochs and annotation scheme. The context size depends on the selected
model: since the RoBERTa model admits a maximum size of 512 tokens, smaller documents
were created from the original reports by performing sentence-based splitting, yet assuring a
minimum size of 128 or 256 tokens. On the other hand, since Longformer models admit up to
4096 tokens per instance, no document splitting was performed in those cases.</p>
      <p>Table 2 shows results obtained by the diferent configurations of the proposed model for the
development and test datasets, evaluated using the weighted B2 metric.</p>
      <p>As we can observe in the table, all results fall within a similar range of weighted B2 values,
which indicates that the diferences between the considered configurations of the model are
not especially relevant. In particular, although the best performing model for the development
dataset is the RoBERTa model with a context size of 256 tokens, this result is not maintained
when it comes to the test dataset. The remaining configurations show consistent results for
both the development and the test datasets, being run 4 (Transformer model trained during
100 epochs, “Simple-NER” annotation scheme) the best performing configuration for the test
dataset. Finally, results for run 5 indicate that despite being more complex and hence more
dificult for the model to learn, the “Full-NER” annotation scheme also allows the system to
obtain competitive results.</p>
      <p>Finally, table 3 shows a comparison of the best performing runs of every team participating
in the ClinAIS competition, evaluated with the weighted B2 metric on the test dataset.</p>
      <p>The table shows how our system is able to obtain the second best result in the competition,
only around 1.5% below the best performing system, and significantly above the third best
system. This indicates that the use of Transformer-based models is an interesting starting point
for performing automatic section identification in medical reports, due to the current ease of
use and adaptation to almost any problem of this type of systems.</p>
    </sec>
    <sec id="sec-6">
      <title>6. Conclusions and Future Work</title>
      <p>This paper describes our participation in the ClinAIS task of the IberLEF 2023 shared evaluation
campaign, devoted to the automatic identification of sections within medical reports. The
main contribution of this research is the use of two diferent Transformer-based models for
performing a NER-like token classification, in which the main objective is to detect those
tokens indicating the beginning of a new section within the report. Two diferent annotation
schemes similar to those employed in NER tasks are also studied. The main results indicate
that these models are useful for accurate detection of the diferent sections and their respective
boundaries. The use of Longformer models, which allow for documents up to 4096 tokens in
length, also avoids the need of particular pre-processing techniques such as sentence splitting.
The best performing configuration of our system is able to achieve the second best result in the
competition.</p>
      <p>As future lines of work, we consider a further analysis and tuning of the hyperparameters
of the deep learning models employed in this work, such as learning rates or loss functions,
as well as the study of additional pre-trained models in order to determine their impact in the
ifnal results. We also envisage the inclusion of additional information such as keywords and
keyphrases in the training loop in order to direct the model’s attention to those expressions able
to more accurately define the beginning or end of a section. Finally, the annotation schemes
should be also studied and refined as much as possible in order to make it easier for the model
to learn the labels associated to the boundaries of the sections.</p>
    </sec>
    <sec id="sec-7">
      <title>Acknowledgments</title>
      <p>This work has been partially supported by the Spanish Ministry of Science and Innovation
within the DOTT-HEALTH Project (MCI/AEI/FEDER, UE) under Grant PID2019-106942RB-C32
and OBSER-MENH Project (MCIN/AEI/10.13039/501100011033 and NextGenerationEU/PRTR)
under Grant TED2021-130398B-C21 as well as project RAICES (IMIENS 2022).
Conference of the Spanish Society for Natural Language Processing (SEPLN 2023),
CEURWS.org, 2023.
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