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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Applications⋆</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Gianfranco Lombardo</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Marco Picone</string-name>
          <xref ref-type="aff" rid="aff3">3</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Diego Reforgiato Recupero</string-name>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Giuseppe Vizzari</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Department of Engineering and Architecture at University of Parma</institution>
          ,
          <country country="IT">Italy</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Department of Informatics, Systems and Communication, Università degli Studi di Milano-Bicocca</institution>
          ,
          <addr-line>Milano</addr-line>
          ,
          <country country="IT">Italy</country>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>Department of Mathematics and Computer Science of the University of Cagliari</institution>
          ,
          <country country="IT">Italy</country>
        </aff>
        <aff id="aff3">
          <label>3</label>
          <institution>Department of Sciences and Methods for Engineering at University of Modena and Reggio Emilia</institution>
          ,
          <country country="IT">Italy</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2023</year>
      </pub-date>
      <abstract>
        <p>The 2023 Workshop on AI for Digital Twins and Cyber-Physical Applications (AI4DT&amp;CP 2023) is at its ifrst edition, held in conjunction with IJCAI 2023: the 32nd International Joint Conference on Artificial Intelligence. The workshop aims to bring together experts in the fields of Artificial Intelligence, Digital Twin technology, and Cyber-Physical systems to explore the latest developments and best practices in the use of AI-based digital twins for a wide range of cyber-physical services and applications. We will discuss recent trends and research projects, as well as developments and advances being made in the area of Digital Twins and Artificial Intelligence to address Cyber-physical applications from diferent perspectives.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;Artificial Intelligence</kwd>
        <kwd>Cyber-physical</kwd>
        <kwd>Digital Twins</kwd>
        <kwd>Internet of Things</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        The availability of easy-to-deploy sensors and the general advances in the Internet of Things
(IoT) technology have led to the emergence of new applications that seamlessly blend the
physical and digital worlds. Notwithstanding this trend, there are still open issues. A major
one, due to the heterogeneity of the several models involved, is dealing with the complexity
of the physical world to develop and deploy intelligent services that continuously perceive
and learn from data coming from the environment. The idea gained traction among both
academic institutions and industry players, revitalizing the Digital Twin technology that enables
the creation of virtual replicas of physical objects by mirroring their properties, data, and
behaviors [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] and enabling new intelligent and augmented functionalities such as learning,
modeling, simulation, and cognitive capabilities. Artificial Intelligence (AI) will transform the
ifeld of Digital Twin technology by enabling the creation of intelligent virtual replicas that
may ofer smart services and lead to adaptive AI in cyber-physical environments [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]. At the
same time, incorporating machine learning models into digital twin systems can be critical
when monitoring or controlling critical systems [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ]. Machine Learning Operations (MLOps)
approaches are attracting increasing interest to ensure that intelligent models are deployed
robustly and reliably, especially when exploiting Continual Learning or Reinforcement Learning
techniques [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. Therefore, we must address these challenges, providing new techniques and
methods and exploring the latest developments and best practices in the use of AI-based digital
twins for a wide range of cyber-physical services and applications.
      </p>
    </sec>
    <sec id="sec-2">
      <title>2. AI for Digital Twin</title>
      <p>
        AI can be used to enhance the performance, safety, and security of Digital Twin and IoT-based
cyber-physical systems by making them more intelligent, adaptive, and autonomous. The results
can be better control, optimization, and prediction of the Cyber-Physical systems [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ].
      </p>
      <p>
        Digital Twin and cyber-physical systems can be enhanced with AI in several ways since AI
enables real-time monitoring and control of physical systems with the possibility of delivering
intelligent services with applications in several domains, such as:
1. Predictive modelling: AI-powered digital twins can predict the behaviour of IoT-based
physical systems under diferent conditions, helping to identify potential issues or
ineficiencies in the physical system before they occur [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ].
2. Anomaly detection: AI-powered digital twins can analyse sensor data from the physical
system in real-time, using machine learning techniques to identify anomalies or deviations
from normal behaviour [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ].
3. Digital Human Replica: Building virtual replicas of humans that reproduce and model
both outer and inner aspects of a human being, such as physical and physiological
characteristics, personality, sensitivities, thoughts and skills [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ].
4. Optimization: AI-powered digital twins can analyse sensor data and other inputs to
optimise the performance of the physical system (e.g., by adjusting the control parameters
to minimise energy consumption or maximise production eficiency) [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ].
5. Autonomous control: AI-powered digital twins can be used to control a IoT-based
physical system autonomously, using sensor data and other inputs to make real-time
decisions.[
        <xref ref-type="bibr" rid="ref3">3</xref>
        ]
6. Safety and security: AI-powered digital twins can be used to monitor and analyse sensor
data to detect security threats or unsafe conditions in the physical system and to trigger
appropriate responses [
        <xref ref-type="bibr" rid="ref10">10</xref>
        ].
      </p>
      <p>At the same time, incorporating machine learning models into digital twin systems can be
critical when monitoring or controlling critical systems. Machine Learning Operations (MLOps)
approaches are attracting increasing interest to ensure that intelligent models are deployed
robustly and reliably, especially when exploiting Continual Learning or Reinforcement
Learning technique.</p>
    </sec>
    <sec id="sec-3">
      <title>3. Topics of interest</title>
      <p>Topics of interest include, but are not limited to, the following:
• What-if scenarios with IoT-based Cyber-Physical applications
• MLOps in Cyber-Physical systems
• Digital Twin intelligence management
• Digital Twins modelling for AI for physical augmentation
• Digital Twins for synthetic data generation in Cyber-Physical applications
• Predictive Maintenance in IoT-based Cyber-Physical systems
• Intelligent Digital Twins for optimization use cases (Smart cities, smart buildings,
environmental monitoring)
• Digital human replica with AI
• IoT-based Cyber-Physical application with AI in healthcare
• Digital Twins for continual learning scenarios
• Reinforcement Learning in IoT-based Cyber-Physical applications
Besides the aforementioned topics of interest, papers can be of the following three types:
• Full research papers(minimum 7 pages)
• Short research papers(4-6 pages)
• Position papers(2 pages)</p>
    </sec>
    <sec id="sec-4">
      <title>4. Submissions</title>
      <p>The AI4DT&amp;CP 2023 Workshop received 5 submissions, of which 4 were accepted. Articles
have been submitted from 5 diferent countries, i.e., France, Germany, South Africa, India and
Japan.</p>
      <p>The accepted articles, collected in these Proceedings, have primarily addressed two topics.
The first issue concerns the usage of machine learning techniques to agument Digital Twins;
the second issue concerns the application of AI-based Digital Twin in the healthcare sector.</p>
      <p>With respect to the first issue, in the article by Theusch et al., entitled: “Towards Machine
Learning-based Digital Twins in Cyber-Physical Systems”, the authors discuss the open problem
related with the systematisation of Machine Learning-based Digital Twins (MLDTs) as well as
their methodological development and implementation processes in productive environments.
In particular, they introduce a novel process model for the systematic development of MLTDs
according to the Machine Learning Operations (MLOps) paradigm which is presented as a
tentative instance of a future reference model for MLDTs. Moreover, they leverage such a process
model to experiment with an industrial use case related with water resource management.</p>
      <p>In the same issue, we can find the article entitled: “Joint Hypergraph Rewiring and
MemoryAugmented Forecasting Techniques in Digital Twin Technology”, by Sakhinana et al. The
authors discuss the open problems in forecasting tasks when Digital Twin are applied to
complex sensor networks that require to adapt to non-stationary environments, retain past
knowledge and which lack a mechanism to capture the higher-order spatio-temporal dynamics,
and estimate uncertainty in model predictions. They propose a hybrid architecture that enhances
the hypergraph representation by incorporating fast adaptation to new patterns and
memorybased retrieval of past knowledge. This balance improve the slowly-learned backbone and
achieve better performance in adapting to recent changes.</p>
      <p>With regard to the second issue related to AI-based Digital Twin for Healthcare, two articles
were accepted. The first, entitled: "Neuro-Symbolic Digital Twins for Precision and Predictive
Public Health" proposes to enable Precision and Predictive Public Health for population health
using Digital Twin, Public Health instruments, knowledge graphs, and AI. In particular, it
introduces Neuro-symbolic Digital Twins, which combine semantic reasoning supported by a
knowledge graph, deep-learning’s predictive power, and a Digital Twins’ agility to simulate
public health interventions in a virtual environment.</p>
      <p>Finally, the article entitled “Re-imagining health and well-being in low resource African
settings using an augmented AI system and a 3D digital twin” by Moodley et al. discusses and
explores the potential and relevance of recent developments in artificial intelligence and digital
twins for health and well-being in low-resource African countries with a specific focus on
public health emergency response to disease outbreaks and epidemic control. In particular, the
authors propose an initial augmented AI system architecture to illustrate how an AI system can
work with a 3D digital twin to address public health goals by leveraging knowledge discovery,
continual learning and pragmatic interoperability for decision-making.</p>
      <p>The workshop attracted several participants and it has been one of the most participated
during the daily session where it was scheduled during IJCAI 2023. Moreover, it enabled fruitful
research discussions that confirmed a promising interest for such domain and challenges.</p>
    </sec>
    <sec id="sec-5">
      <title>5. Organizing team</title>
      <p>Gianfranco Lombardo is Assistant Professor at the Department of
Engineering and Architecture (DIA) of the University of Parma. He teaches Mobile
Computing and Introduction to Artificial Intelligence and Big Data in the
same university. He holds a PhD in Information Technologies. In 2019 he
was visiting researcher at the Center for Applied Optimization (CAO) at the
Herbert Wertheim College of Engineering of the University of Florida (United
States). He is currently an external AI consultant for the European Food
and Safety Authority (EFSA) for a European industrial project, and he is the
co-founder of an American startup focused on delivering AI products in Finance. He currently
serves as a reviewer for several Elsevier, Springer and IEEE journals on topics related to Artificial
Intelligence. In 2022 he organized a workshop at the International Conference on Machine
Learning, Optimization and Data science (LOD). In 2018 he was in the local organizing team of
EVOSTAR 2018 and WIVACE 2018.</p>
      <p>Marco Picone is Assistant Professor (RTD-B) at the Department of
Sciences and Methods for Engineering (DISMI) of the University of Modena
and Reggio Emilia. He received the Ph.D. in Information Technology and
the M.Sc. (cum Laude) in Computer Engineering from the University of
Parma (Italy) and he have also been Postdoctoral Research Associate at the
same University from 2012 and 2015. During 2011 he was a visiting student
researcher in the NetOS group at the Computer Laboratory, University of
Cambridge (UK). His research interests include Distributed Systems, Internet
of Things, Edge Computing, Digital Twins, Pervasive and Mobile Computing. He is the author
of several scientific publications on international conferences and journals and he published
two books titled on Internet of Things and Intelligent Transportation Systems. He has a strong
background in middleware and infrastructure for pervasive and interoperable IoT systems and
is active in the Digital Twins (DTs) research both from a modeling and design perspective and
from the software engineering, development, interoperability, and deployment point of view.
He have been directly involved in the organization and participation in international workshops
(TwinNets 2022 and 2023 - http://www.twinnets.unipi.it/) and journals special issues (Elsevier
Computer Communications - Special issue on "Digital Twins for the Computer-Networks
Evolution" - Link) related to the Digital Twin topic with the aim to create a shared community on
the topic. Furthermore, he is the designer, developer, and main maintainer of the White Label
Digital Twin OpenSource project a Java-based library for the creation of Digital Twins for IoT
applications and use cases (https://github.com/wldt).</p>
      <p>Diego Reforgiato Recupero is a Full Professor at the Department of
Mathematics and Computer Science of the University of Cagliari, Italy. He
holds a double bachelor’s degree from the University of Catania in computer
science and a doctoral degree from the Department of Computer Science of
the University of Naples Federico II. He is the co-director of the Semantic
Web Laboratory at the University of Cagliari http://swlab.unica.it and founder
and director of the Human-Robot Interaction laboratory at the University
of Cagliari https://hri.unica.it/ and founder and director of the Artificial
Intelligence and Big Data Laboratory at the University of Cagliari https://aibd.unica.it. He is also
the coordinator of the new bachelor’s degree in Applied Computer Science and Data Analytics
at the University of Cagliari and co-founder of six companies, three of which are spin-ofs of the
University of Maryland, CNR and the University of Cagliari. He is the author of more than 200
scientific papers and has organised more than 15 International workshops. Among those who
obtained the highest success in terms of participants and impact, he has previously organised
the six editions of the International Workshop on Deep Learning for Knowledge Graphs at the
Extended Semantic Web Conference and the International Semantic Web Conference and is
going to organise the forthcoming. Much of the research of Prof. Reforgiato revolves around
Deep Learning, Machine Learning and Semantic Web.</p>
      <p>Giuseppe Vizzari has organized several workshops and symposia on the
topics of agent-based modelling and simulation, in particular, he was
cochair of the ABModSim workshop series (four editions, from 2006 to 2012) in
the context of the European Meeting on Cybernetics and Systems Research,
and the Advances in Computer Simulation symposium in the context of
the ACM Symposium on Applied Computing (2008, 2009 and 2010 editions).
He was also workshop co-chair of the 2009 IEEE/WIC/ACM International
Joint Conference on Web Intelligence and Intelligent Agent Technology
(WIIAT’09), Milano (Italy), Sept. 15-18, 2009. He is a member of the steering committee of the
Agents in Trafic and Transportation (ATT) workshop series, and he was a member of the</p>
    </sec>
    <sec id="sec-6">
      <title>Acknowledgments</title>
      <p>The authors would like to thank the organizing committee of the 32nd International Joint
Conference on Artificial Intelligence (IJCAI 2023) for hosting this first edition of the workshop.</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          [1]
          <string-name>
            <given-names>F.</given-names>
            <surname>Tao</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Zhang</surname>
          </string-name>
          , A. Nee, Chapter 1
          <article-title>- background and concept of digital twin</article-title>
          , in: F. Tao,
          <string-name>
            <given-names>M.</given-names>
            <surname>Zhang</surname>
          </string-name>
          , A. Nee (Eds.),
          <source>Digital Twin Driven Smart Manufacturing</source>
          , Academic Press,
          <year>2019</year>
          , pp.
          <fpage>3</fpage>
          -
          <lpage>28</lpage>
          . doi:https://doi.org/10.1016/B978-0
          <source>-12-817630-6</source>
          .
          <fpage>00001</fpage>
          -
          <lpage>1</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          [2]
          <string-name>
            <given-names>M.</given-names>
            <surname>Groshev</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            <surname>Guimarães</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            <surname>Martín-Pérez</surname>
          </string-name>
          , A. de la Oliva,
          <article-title>Toward intelligent cyber-physical systems: Digital twin meets artificial intelligence</article-title>
          ,
          <source>IEEE Communications Magazine</source>
          <volume>59</volume>
          (
          <year>2021</year>
          )
          <fpage>14</fpage>
          -
          <lpage>20</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref3">
        <mixed-citation>
          [3]
          <string-name>
            <given-names>Z.</given-names>
            <surname>Zhao</surname>
          </string-name>
          ,
          <string-name>
            <given-names>L.</given-names>
            <surname>Shen</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            <surname>Yang</surname>
          </string-name>
          ,
          <string-name>
            <given-names>W.</given-names>
            <surname>Wu</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Zhang</surname>
          </string-name>
          ,
          <string-name>
            <given-names>G. Q.</given-names>
            <surname>Huang</surname>
          </string-name>
          ,
          <article-title>Iot and digital twin enabled smart tracking for safety management</article-title>
          ,
          <source>Computers &amp; Operations Research</source>
          <volume>128</volume>
          (
          <year>2021</year>
          )
          <fpage>105183</fpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref4">
        <mixed-citation>
          [4]
          <string-name>
            <given-names>G.</given-names>
            <surname>Lombardo</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Picone</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Mamei</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Mordonini</surname>
          </string-name>
          ,
          <string-name>
            <given-names>A.</given-names>
            <surname>Poggi</surname>
          </string-name>
          ,
          <article-title>Digital twin for continual learning in location based services</article-title>
          ,
          <source>Engineering Applications of Artificial Intelligence</source>
          <volume>127</volume>
          (
          <year>2024</year>
          )
          <fpage>107203</fpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref5">
        <mixed-citation>
          [5]
          <string-name>
            <given-names>M.</given-names>
            <surname>Grieves</surname>
          </string-name>
          ,
          <article-title>Intelligent digital twins and the development and management of complex systems</article-title>
          ,
          <source>Digital Twin</source>
          <volume>2</volume>
          (
          <year>2022</year>
          )
          <article-title>8</article-title>
          .
        </mixed-citation>
      </ref>
      <ref id="ref6">
        <mixed-citation>
          [6]
          <string-name>
            <given-names>O.</given-names>
            <surname>Hashash</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            <surname>Chaccour</surname>
          </string-name>
          , W. Saad,
          <article-title>Edge continual learning for dynamic digital twins over wireless networks</article-title>
          ,
          <source>arXiv preprint arXiv:2204.04795</source>
          (
          <year>2022</year>
          ).
        </mixed-citation>
      </ref>
      <ref id="ref7">
        <mixed-citation>
          [7]
          <string-name>
            <given-names>P.</given-names>
            <surname>Klein</surname>
          </string-name>
          ,
          <string-name>
            <given-names>N.</given-names>
            <surname>Weingarz</surname>
          </string-name>
          ,
          <string-name>
            <given-names>R.</given-names>
            <surname>Bergmann</surname>
          </string-name>
          ,
          <article-title>Enhancing siamese neural networks through expert knowledge for predictive maintenance</article-title>
          , in: International workshop on IoT, Edge, and
          <source>Mobile for Embedded Machine Learning</source>
          , Springer,
          <year>2020</year>
          , pp.
          <fpage>77</fpage>
          -
          <lpage>92</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref8">
        <mixed-citation>
          [8]
          <string-name>
            <given-names>T.</given-names>
            <surname>Sun</surname>
          </string-name>
          ,
          <string-name>
            <given-names>X.</given-names>
            <surname>He</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Z.</given-names>
            <surname>Li</surname>
          </string-name>
          ,
          <article-title>Digital twin in healthcare: Recent updates and challenges</article-title>
          ,
          <source>Digital Health</source>
          <volume>9</volume>
          (
          <year>2023</year>
          )
          <fpage>20552076221149651</fpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref9">
        <mixed-citation>
          [9]
          <string-name>
            <given-names>Q.</given-names>
            <surname>Min</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Y.</given-names>
            <surname>Lu</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Z.</given-names>
            <surname>Liu</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            <surname>Su</surname>
          </string-name>
          ,
          <string-name>
            <given-names>B.</given-names>
            <surname>Wang</surname>
          </string-name>
          ,
          <article-title>Machine learning based digital twin framework for production optimization in petrochemical industry</article-title>
          ,
          <source>International Journal of Information Management</source>
          <volume>49</volume>
          (
          <year>2019</year>
          )
          <fpage>502</fpage>
          -
          <lpage>519</lpage>
          .
        </mixed-citation>
      </ref>
      <ref id="ref10">
        <mixed-citation>
          [10]
          <string-name>
            <given-names>T.</given-names>
            <surname>Ritto</surname>
          </string-name>
          ,
          <string-name>
            <given-names>F.</given-names>
            <surname>Rochinha</surname>
          </string-name>
          ,
          <article-title>Digital twin, physics-based model, and machine learning applied to damage detection in structures</article-title>
          ,
          <source>Mechanical Systems and Signal Processing</source>
          <volume>155</volume>
          (
          <year>2021</year>
          )
          <fpage>107614</fpage>
          .
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>