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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>International Journal of Grid and Utility Computing</journal-title>
      </journal-title-group>
      <issn pub-type="ppub">1613-0073</issn>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.1109/ACCESS.2020.2992526</article-id>
      <title-group>
        <article-title>Real-time Health Monitoring Computer System Based on Internet of Medical Things</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Andriy Palamar</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Mykhaylo Palamar</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Halyna Osukhivska</string-name>
          <email>osukhivska@tntu.edu.ua</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Workshop</string-name>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Ternopil Ivan Puluj National Technical University</institution>
          ,
          <addr-line>Ruska str., 56, Ternopil, 46001</addr-line>
          ,
          <country country="UA">Ukraine</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2020</year>
      </pub-date>
      <volume>8</volume>
      <issue>3</issue>
      <fpage>84792</fpage>
      <lpage>84805</lpage>
      <abstract>
        <p>In the era of advanced technology and connectivity, the IoT has revolutionized various realms, including healthcare. This research contributes to the field of intelligent information computer systems and technologies, specifically in the domain of applied information technologies in medicine. This paper presents a health monitoring system development exploiting the Internet of Medical Things (IoMT). The system is built upon the ESP32 platform, integrated with sensors for oxygen saturation, pulse and temperature measurements. Information collected by the ESP32 module is transmitted to IoT cloud-based service for storage, data visualization, and future analysis. The proposed computer system addresses the growing demand for continuous health monitoring, especially for elderly individuals, and provides a solution for remote healthcare management. It focuses to bridge the gap among traditional healthcare and the capabilities offered by IoMT, providing real-time observations of a person's health status. The integration of ESP32 platform and specialized sensors facilitates the collection of vital health data, which can be crucial in identifying health anomalies and improving healthcare outcomes. The results demonstrate the feasibility and effectiveness of an IoMT-based solution for realtime health monitoring, accelerating the way for boosted healthcare services in an increasingly connected world.</p>
      </abstract>
      <kwd-group>
        <kwd>Internet of Medical Things</kwd>
        <kwd>computer system</kwd>
        <kwd>IoMT</kwd>
        <kwd>ESP32</kwd>
        <kwd>sensors</kwd>
        <kwd>real-time monitoring</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        The rapid advancement of information technology and the connected devices propagation have
ushered in a new era of innovation, particularly in the healthcare realm. The Internet of Things (IoT)
[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] has emerged as a transformative force, enabling the development of intelligent systems that have
the potential to revolutionize how we monitor and manage health. In this context, the Internet of Medical
Things (IoMT) [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] represents a specialized branch of IoT tailored for healthcare applications, offering
unprecedented opportunities for real-time health monitoring and remote healthcare management.
      </p>
      <p>As the global population ages, the demand for continuous health monitoring and personalized
healthcare solutions has grown exponentially. Elderly individuals, in particular, often require vigilant
oversight and timely intervention to address health concerns. However, the majority of family members
and caregivers find themselves constrained by the demands of their daily routines, limiting their ability
to provide constant, in-person care. This challenge has been further exacerbated by the constraints
imposed by quarantine measures and the need for social distancing in recent times.</p>
      <p>In recent years, the medicine development has been characterized by the active introduction of
information technology. Automated computer systems are being designed for use in
medical
institutions. To address these evolving healthcare needs, the development of an effective and reliable</p>
      <p>2023 Copyright for this paper by its authors.
CEUR</p>
      <p>
        ceur-ws.org
system for real-time health monitoring becomes relevant. Such a system should not only provide
continuous insights into a person's health status but also enable healthcare professionals and caregivers
to remotely access and analyze vital health data, facilitating early diagnosis. The IoMT holds the
promise of fulfilling these requirements by seamlessly integrating connectivity technologies, medical
devices and sensors [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ].
      </p>
      <p>The primary goal of this work is to design and implement a cost-effective and accurate health
monitoring system (HMS) based on IoMT. This system aims to provide vital signs real-time monitoring,
including temperature and pulse oximetry, for patients with chronic illnesses and individuals seeking
improved health management. The system integrates IoT devices with data visualization means to
provide remote patient monitoring by healthcare specialists. Ultimately, the goal is to enhance the
patient care efficiency, decrease healthcare costs and refine overall healthcare outcomes through the
seamless integration of IoT and sensor technologies.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Related works</title>
      <p>The development of real-time HMSs, especially those leveraging the IoMT, has gained great
attention in recent years. A variety of IoMT-based HMSs have been proposed in the literature. These
systems typically incorporate a sensors network and medical devices to accumulate and transmit health
data. Cloud computing plays a pivotal role in health data storage, analysis and accessibility. Numerous
cloud-based healthcare services have emerged to handle the vast data amount generated by HMSs.
These solutions enable secure data storage and real-time information sharing with healthcare providers.</p>
      <p>
        Researchers have explored diverse IoMT architectures and sensor combinations to cater to specific
healthcare needs. Several key contributions in the field of HMSs were reviewed in this section. These
studies predominantly revolved around the integration of Internet of Things [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ] and sensor technologies
for remote patient monitoring [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ].
      </p>
      <p>
        The paper [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ] introduces an architecture for monitoring elderly patients using the IoMT. It addresses
the need for home-based diagnostic and monitoring systems for the elderly, emphasizing data
processing at fog, edge or cloud levels based on workload and confidentiality. While authors offer
potential solutions for continuous monitoring and data security through blockchain and AI, it leaves
unresolved issues regarding usability and long-term viability, which need further consideration for
realworld healthcare implementation.
      </p>
      <p>
        The article [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ] presents an intelligent IoMT-based system designed for real-time patient monitoring.
While this system boasts advantages in terms of cost, accuracy, portability, and real-time
responsiveness, it lacks a comprehensive discussion of the challenges or limitations faced during its
development and implementation. Further solving of potential scalability and usability issues in diverse
healthcare settings would enhance the understanding of its practical applicability.
      </p>
      <p>
        The paper [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ] reviews the implementation of IoMT-based remote HMS through wearable sensors,
with a focus on diabetic patients. It emphasizes the importance of IoMT in the future of healthcare and
highlights the monitoring of vital signs, including glucose levels.
      </p>
      <p>
        The authors in [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ] present an IoT-based HMS designed to continuously track the health function
status of elderly individuals living alone. The system employs sensor technology and machine learning
classifiers to assess both physiological and behavioral indicators. Although the paper discusses the
potential for real-time monitoring, it doesn't provide insights into the practical challenges and
considerations when implementing the system in real-world IoT environments.
      </p>
      <p>
        Research published in [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ] focuses on an IoT-based HMS using a wearable glove to detect and
analyze heart rate and EEG for stroke management. While the study discusses the reduction in
complexity for healthcare providers, it would benefit from a more comprehensive discussion of clinical
validation and its impact on stroke prevention and management.
      </p>
      <p>The paper [10] delves into the emerging field of the IoMT and its potential applications in health
and sports data collection. It focuses on the use of temperature and acceleration sensors to gather
information related to human health and physical activity, with an emphasis on modeling and data
analysis. While the article presents promising findings, it highlights the complexity of the IoMT system
and the need for further research to address architectural challenges and ensure reliable data acquisition.</p>
      <p>In [11] the design of a HMS based on IoT has been described. The paper emphasizes the potential
of IoT in revolutionizing healthcare. The system is designed to collect and process health-related data
from various sensors, allowing for real-time monitoring and prediction of health conditions. While the
article presents a promising prototype, it does not delve into the challenges and limitations that may
arise during the practical implementation of such a system, particularly in terms of scalability, and user
adoption. Further research and development are needed to address these issues and ensure the system's
effectiveness and reliability.</p>
      <p>The paper [12] introduces an intelligent system based on the IoT for remote health monitoring. While
the system presents benefits such as real-time monitoring and instant notifications to healthcare
professionals, it doesn't delve deeply into potential challenges and issues that may arise during the
widespread implementation of such a system. The system's potential limitations, such as sensor
accuracy and reliability, are not discussed in the paper.</p>
      <p>In [13] has presented a remote intelligent medical HMS based on IoT for real-time acquisition and
storage of patient's physiological parameters. While the system offers benefits in enhanced medical
services and remote patient monitoring, further research and practical implementation are needed to
ensure the system's effectiveness and its ability to meet the complex requirements of remote medical
monitoring.</p>
      <p>The research [14] discusses the architecture of a wearable HMS based on IoT technology,
highlighting its potential benefits in monitoring and protecting the health of aging populations.
However, the paper does not delve into the specific challenges and limitations of implementing such a
system. It briefly mentions difficulties related to mastering and predicting health conditions but does
not provide in-depth solutions or considerations for addressing these challenges.</p>
      <p>The paper [15] presents a monitoring system for vital signs, particularly focusing on sleep quality
and heart rate changes, catering to the elderly, sub-health individuals, and those with insomnia. The
system employs IoT devices to collect information and transmit it to a cloud platform for analysis and
monitoring.</p>
      <p>The article [16] addresses the need for cost-efficient HMSs based on IoT and big data technology.
It acknowledges the high cost associated with implementing IoT-based healthcare devices on a large
scale and the challenge of efficiently managing the information generated by these devices. The
proposed design offers a holistic approach that includes affordable sensing hardware and a data
management platform based on big data technology. While the paper presents a promising solution to
reduce costs in healthcare monitoring, it doesn't deeply explore potential challenges related to data
security, which are critical considerations in healthcare IoT applications.</p>
      <p>The authors in [17] introduce a visualization system based on the IoMT, aiming to help healthcare
professionals monitor patient health condition in real-time. The system's user satisfaction is assessed,
showing positive results in terms of usability and user-friendliness. However, the article does not
provide technical details regarding the technology used and the testing methodology.</p>
      <p>In [18] has proposed the development of a remote HMS based on IoT and the MQTT protocol. It
aims to provide accurate real-time vital sign data to healthcare specialists via a web interface. While the
study presents a promising solution for remote patient monitoring and highlights the importance of
security and privacy, it doesn't delve deeply into potential issues related to the interoperability with
existing healthcare systems.</p>
      <p>Many researchers have recognized the potential of IoT in transforming healthcare by enabling
real-time data gathering and analysis [19]. Some notable works highlighted the importance of data
visualization tools [20–22] to aid healthcare professionals in monitoring and diagnosing patients.
These related works paved the way for this research, emphasizing the need for cost-efficient,
accurate and user-friendly health monitoring solutions, which are addressed through the proposed
system.</p>
      <p>While these related works offer valuable insights into the development of HMSs, this research
distinguishes itself by focusing on the integration of ESP32 platform and specialized sensors for
lowcost real-time health monitoring. Additionally, we emphasize the practical application of our system
for remote healthcare management, early anomaly detection, and scalability, contributing to the broader
landscape of intelligent information technologies and computerized systems in medicine.</p>
    </sec>
    <sec id="sec-3">
      <title>3. System structure</title>
      <p>The designed system leverages the capabilities of the ESP32 platform, coupled with specialized
sensors for pulse, oxygen saturation and temperature measurements. The designed HMS is a
comprehensive structure that seamlessly integrates various components to enable real-time monitoring
and data analysis. The key components of this system include: ESP32 module, МАХ30205 temperature
sensor, МАХ30102 pulse oximeter and heart rate sensor, OLED display, IoT cloud server, laptop,
computer or smartphone.</p>
      <p>The selection of appropriate sensors, such as the МАХ30205 and МАХ30102 used in the designed
system, was emphasized for accurate and reliable data acquisition. МАХ30205 temperature sensor
provides precise measurements. It is crucial for monitoring a patient's body temperature, especially for
detecting fever or abnormal temperature fluctuations. МАХ30102 sensor is responsible for monitoring
both pulse rate and blood oxygen saturation levels. It is a valuable component for assessing a patient's
cardiovascular health and oxygen levels in the blood.</p>
      <p>ESP32-based module serves as the central hub of the system. It facilitates communication with the
sensors via the I2C interface and connects to the IoT cloud server via a WiFi interface. OLED display
provides a clear and user-friendly interface for displaying vital signs data in real-time. It enhances the
user experience by making data easily accessible and readable.</p>
      <p>The IoT cloud server acts as the central data repository. It receives data from the ESP32 module via
WiFi and stores it securely in the cloud. This server also hosts data processing algorithms and analysis
tools. The proposed system architecture for the designed HMS based on the IoMT concept is shown
in Figure 1.</p>
      <p>The system follows this structure: The МАХ30205 and МАХ30102 sensors continuously collect
vital signs data, including temperature, pulse rate, and blood oxygen saturation. This information is
transmitted to the ESP32 module via the I2C interface. The ESP32 module processes the data, displays
it in real-time on the OLED display and securely sends it to the IoT cloud server via WiFi. Healthcare
professionals and patients can access the data through laptops, computers or smartphones, using
userfriendly interfaces. These devices serve as user interfaces, allowing users to monitor vital signs and
access real-time health data. The IoT cloud server hosts data analysis algorithms to provide real-time
insights into a patient's health status.</p>
      <p>Overall, this structured system enables efficient remote patient monitoring, promotes early detection
of health irregularities, and enhances healthcare services through IoT technology and data analysis.</p>
    </sec>
    <sec id="sec-4">
      <title>4. System implementation</title>
    </sec>
    <sec id="sec-5">
      <title>4.1. Hardware design</title>
      <p>An electrical scheme of the designed health monitoring module for the proposed system is shown in
Figure 2.</p>
      <p>In this schematic the МАХ30205 temperature sensor (U1) is responsible for accurately measuring
body temperature. The МАХ30102 sensor (U2) concurrently monitors pulse rate and blood oxygen
saturation levels. Both U1 and U2 are connected to the ESP32 module (U3) through the I2C
communication protocol, enabling seamless data transmission between the sensors and the
microcontroller.</p>
      <p>The ESP32 module acts as the central processing unit, collecting, processing, and displaying the
health data obtained from U1 and U2 on the OLED display (D1). It transmits the collected data
wirelessly to an IoT cloud server.</p>
      <p>To ensure continuous operation, the system is powered by a rechargeable battery (B1), providing a
portable and self-contained solution for health monitoring. The TP4056 module (U4) is responsible for
efficiently charging and managing the Li-Ion battery B1 used to power the system. It ensures that the
battery remains in good condition and provides a stable power source for the components. This
schematic diagram represents a basic setup for monitoring key health parameters, making it a versatile
platform for various healthcare and wellness applications.</p>
      <p>The hardware prototype of the HMS based on the described scheme is illustrated in the Figure 3.
The hardware components of the prototype include the ESP32 DEVKITV1 module, МАХ30205 and
МАХ30102 sensors, and an OLED display. They are arranged on a breadboard and connected using
wires. The OLED display shows information related to pulse rate, oxygen saturation, and temperature.</p>
      <p>The ESP32 DEVKITV1 module is a versatile development board that integrates an
ESP32D0WDQ6 microcontroller, and various GPIO pins for extended functionality. The ESP32
microcontroller provides Wi-Fi and Bluetooth connectivity, making it suitable for wireless data
transmission in health monitoring applications. It also features a micro USB port for programming and
power supply.</p>
      <p>The МАХ30205 sensor is a vital component in the HMS, providing accurate temperature
measurements. With an impressive accuracy of 0.1°C within the critical temperature range of 37°C to
39°C, this sensor ensures precise and reliable monitoring of a patient's body temperature. Its I2C
interface seamlessly integrates with the ESP32 module, making it an ideal choice for health monitoring
applications where temperature accuracy is paramount.</p>
      <p>The МАХ30102 sensor plays a pivotal role in our HMS, focusing on pulse and blood oxygen
saturation (SpO2) measurements. This sensor boasts exceptional accuracy, making it a reliable choice
for healthcare applications. Its ability to provide precise readings for pulse rate and SpO2 levels ensures
the system's reliability and effectiveness. The МАХ30102 sensor is integrated into the system via the
I2C interface.</p>
      <p>The OLED display is responsible for real-time visualization of vital signs, making it a robust choice
for the designed HMSs.
4.2.</p>
    </sec>
    <sec id="sec-6">
      <title>Software development</title>
      <p>The software for the designed HMS plays a crucial role in collecting, processing, and presenting
vital signs data efficiently. The software for the microcontroller of the designed system was developed
using the Wiring programming language, which is derived from C++, within the Arduino IDE. The
code fragment for ESP32, which is responsible for calculating the heart rate and processing the data
obtained from the MAX30102 sensor is shown in Figure 4.</p>
      <p>The software for the ESP32 microcontroller interfaces with the МАХ30205 temperature sensor and
the МАХ30102 pulse oximeter sensor via the I2C protocol. It collects real-time data from these sensors.
Once the data is collected, the software processes it to ensure accuracy and reliability. This includes
error checking and data validation to filter out any anomalies or outliers. The system's user interface is
displayed on the OLED display. It provides real-time visualizations of vital signs data, making it
accessible to healthcare professionals and patients.</p>
      <p>The ESP32 module connects to the IoT cloud server via a WiFi interface. The software manages the
secure transmission of vital signs data to the cloud server, where it is stored for further analysis and
access from authorized devices. The cloud-based component of the software manages the reception,
storage, and retrieval of patient data. It includes database management, security measures, and data
analytics capabilities to process incoming data efficiently.</p>
      <p>The monitoring results are transmitted to the ThingSpeak cloud-based IoT platform, where they are
displayed in real-time as graphical representations. Additionally, the collected data is stored for an entire
year, providing a comprehensive historical record. Users have the capability to export the data for
further analysis and leverage MATLAB tools for in-depth data analytics.</p>
      <p>ThingSpeak is a robust IoT platform that offers various features and functionalities, making it an
ideal choice for this HMS. Some of its valuable capabilities comprise real-time data visualization
through customizable charts and graphs, data storage with extended retention periods, data export
options, and compatibility with MATLAB for advanced data analysis. ThingSpeak simplifies IoT data
management, enabling users to effortlessly monitor, analyze, and visualize information from the
connected device in a user-friendly and accessible manner.</p>
      <p>In the event of critical health conditions or anomalies in vital signs data, the software can generate
alerts and notifications. These notifications can be sent to healthcare providers' devices or directly to
patients, enabling timely intervention.</p>
      <p>The software for the HMS is developed to be user-friendly, secure, and capable of handling
realtime data processing and transmission. It facilitates effective healthcare monitoring, enhances patient
care and supports in making informed decisions.</p>
    </sec>
    <sec id="sec-7">
      <title>5. Experimental results and discussion</title>
      <p>Figure 5 represents the setup of the designed system with a patient’s finger is placed on the sensors
that are located side by side. The sensors integrated into the system, including the МАХ30102 and the
МАХ30205, consistently provided accurate and reliable health parameter measurements. As a result of
this interaction, the OLED display displays the measured health parameters, including pulse rate, blood
oxygen saturation level and body temperature. This image visually demonstrates the functionality of
the HMS and how it captures and displays real-time health data when a finger is placed on the sensors.
The experimental results are demonstrated a high degree of precision in capturing the vital health data.</p>
      <p>The ESP32 microcontroller effectively accumulated and transmitted health data to the cloud-based
platform ThingSpeak in real-time. The measurement results of vital health data are shown in Figure 6.</p>
      <p>The results obtained from our experiments highlight the effectiveness and practicality of the
designed HMS. By leveraging IoMT and the ESP32 platform, the proposed system empowers
caregivers and healthcare providers with the ability to remotely monitor patient's health parameters.
This ensured timely access to health information, enabling rapid responses to changing health
conditions. This is especially valuable in situations where in-person monitoring is challenging or
impossible.</p>
      <p>The collected health data can be leveraged for advanced data analytics and predictive modeling. This
opens up possibilities for identifying patterns, trends, and early warning signs of health conditions. The
system exhibited minimal response time, enabling quick detection of health anomalies and the
generation of timely alerts. This rapid response time is critical for healthcare professionals and
caregivers to intervene promptly.</p>
      <p>While these results have demonstrated the effectiveness of the proposed system in providing
realtime accurate and reliable health data measurements, several avenues for future exploration remain.
Further refinement of data analytics algorithms and the integration of telemedicine capabilities are
among the directions to consider for future research.</p>
    </sec>
    <sec id="sec-8">
      <title>6. Conclusions</title>
      <p>In the age of digital transformation and interconnected healthcare, the development of a health
monitoring system based on the IoMT using the ESP32 platform has shown remarkable potential and
significance. Through this research, it were achieved several key outcomes and drawn noteworthy
conclusions. The integration of IoMT technologies, including the ESP32 microcontroller and
specialized sensors, provides a robust foundation for real-time health monitoring. The system enables
the continuous collection and transmission of vital health data, bridging the gap between traditional
healthcare and the digital age.</p>
      <p>The proposed system offers a practical solution for remote healthcare management. Caregivers,
healthcare professionals, and family members can remotely access and monitor an individual's health
status, enhancing the quality of care and enabling timely interventions when necessary. The real-time
nature of the system allows for the early detection of health anomalies and deviations from baseline
measurements. This capability is particularly valuable in preventing adverse health events and
improving healthcare outcomes. The modular architecture of our system allows for scalability and
adaptability to different healthcare settings and patient needs. Additional sensors and functionalities can
be seamlessly integrated to cater to specific healthcare scenarios.</p>
      <p>The designed system offers a promising approach to address the evolving healthcare needs of our
society. By leveraging IoMT technologies, it was showcased the potential to transform delivery of
healthcare, enhance patient care, and contribute to the advancement of intelligent information systems
in medicine.</p>
    </sec>
    <sec id="sec-9">
      <title>7. References</title>
    </sec>
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