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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Conference and Labs of the Evaluation Forum, September</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>REBECCA at eRisk 2024: Search for Symptoms of Depression Using Sentence Embeddings and Prompt-Based Filtering</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Anna Barachanou</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Filareti Tsalakanidou</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Symeon Papadopoulos</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Information Technologies Institute, Centre for Research and Technology Hellas (CERTH)</institution>
          ,
          <addr-line>Thessaloniki</addr-line>
          ,
          <country country="GR">Greece</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2024</year>
      </pub-date>
      <volume>0</volume>
      <fpage>9</fpage>
      <lpage>12</lpage>
      <abstract>
        <p>Depression is a complex mental health disorder characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in daily activities. It significantly afects an individual's well-being, impairing their ability to work, socialize with others and be creative. Social media is used by billions of people globally who interact and generate an abundance of posts and texts. Analysis of social interaction data ofers opportunities to gain valuable insights into people's mental health and potentially take supportive action. eRisk 2024 focuses on the challenge of early risk detection on the Internet and has established a number of tasks for this reason. We participated in Task 1: Search for symptoms of depression. The aim of this task is to rank user sentences in terms of 21 symptoms of depression. This paper presents our approach combining ranking sentences using cosine similarity and Transformer embeddings and refining our results with the use of a Large Language Model (LLM). Our LLM-refined approach was among the best performing ones among the 29 runs submitted by the 9 participating teams.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;early risk detection</kwd>
        <kwd>natural language processing</kwd>
        <kwd>depression</kwd>
        <kwd>text retrieval</kwd>
        <kwd>prompt engineering</kwd>
        <kwd>transformers</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Depression is a debilitating mental health condition afecting 5% of people worldwide according to
WHO (World Health Organization)1. Individuals sufering from depression experience a variety of
symptoms beyond a persistently depressed mood and dysphoria. Depression may also manifest as a
loss of interest in activities they once enjoyed, significant changes in sleep and appetite, feelings of
guilt and hopelessness, fatigue, restlessness, problems with concentration and even suicidal ideation
[
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. Beck’s Depression Inventory (BDI-II) [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] is one of the most widely used psychometric assessment
tools for depression and it is designed in the form of a questionnaire measuring the severity of such
symptoms of depression in adolescents and adults.
      </p>
      <p>In today’s digitally connected world, social media such as Facebook, Instagram, YouTube, Twitter, etc.
are being used by more than 4.76 billion people worldwide2. Among these users, there are many people
afected by mental health conditions including depression. Through social media, users interact and
share their thoughts, opinions and emotions with others. As a result, there are vast amounts of data
generated every day that could potentially be leveraged to provide insights into their mental well-being.
This presents a unique opportunity for mental health professionals and researchers to analyze language
patterns by using modern Natural Language Processing (NLP) techniques. By examining the textual
content shared on social media, it should be possible to build methods for early detection of depression.</p>
      <p>Early detection of risk factors such as depression can prevent numerous negative outcomes to an
individual’s life. Recognizing and addressing symptoms of depression early on, facilitates timely helpful
intervention and support, which can significantly improve the efectiveness of treatment. Individuals
are more likely to respond positively to treatment when intervention begins early and avoid intensified
and persistent symptoms. Especially because depression is a major risk factor for suicide, the early ofer
of support can potentially minimize the risk of suicide and suicidal behaviors. This will eventually lead
to an enhanced quality of life free of symptoms of depression, enabling individuals to engage actively
and socially in their everyday life.</p>
      <p>
        The eRisk lab of CLEF (Conference and Labs of the Evaluation Forum), focuses on early risk prediction
on the Internet. Ever since their beginning in 2017 when they piloted a task on Early Detection of
depression [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ], eRisk’s primary objective has been depression which then expanded to include tasks
related to other mental illnesses as well. In this paper, we present our participation, motivated by our
involvement in the Horizon 2020 REBECCA project, in Task 1: Search for symptoms of depression. This
task is a continuation of the same task in eRisk 2023. We were inspired by the systems developed by the
participating teams and we attempted to improve results with the use of Large Language Models (LLMs)
and prompt engineering. Moreover, traditional information retrieval methods such as BM25 or TF-IDF
can efectively handle document ranking but often lack the semantic depth needed for precise results.
Given that depression is a complex and delicate subject, there is a need for highly accurate methods
in order to rank sentences with respect to depression symptoms. We initially ranked the sentences to
the symptoms using Transformer embeddings and computed the ranking scores with cosine similarity.
Subsequently, we decided to leverage the reasoning capabilities of an LLM (namely GPT-4) to refine
the results of the base method, emulating the process of providing relevance feedback and removing
all non-relevant sentences that do not reflect the author’s state about the symptoms. Our methods
achieved highly competitive results among the 9 participating teams, outperforming all competing
approaches in terms of Precision@10 in the unanimity setting, and revealed potential in the systems
we developed and especially in utilizing GPT-4 to better grasp the concepts of depression in sentences.
      </p>
    </sec>
    <sec id="sec-2">
      <title>2. Related work</title>
      <p>
        A significant portion of the related literature about depression is focused on depression identification.
For example, Jamil et al. [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ] aimed to identify depression from individual tweets and assess the risk of
depression from a user’s set of tweets. They computed a small number of features, using indicators like
the percentage of depressed tweets, self-reported depression, BOW, and other lexical features. They
also employed SVM for classification and used balancing methods like undersampling and SMOTE.
Similarly, Peng et al. [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ] used various ML models and multi-kernel SVM to combine features from
a user’s texts, profile and behaviour. While, Chen et al. [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ] used emotion analysis with EMOTIVE
[
        <xref ref-type="bibr" rid="ref7">7</xref>
        ], linguistic features from LIWC, and behavioral features to identify mental health conditions and
employed several ML models for the classification task.
      </p>
      <p>
        eRisk 2023 [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ] established three tasks surrounding mental health, including Task 1: Search for
symptoms of depression. The task we are currently participating in is a continuation of this, with
the aim of expanding research further on this promising topic. The Formula-ML team [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ] achieved
the best performance by leveraging Transformer embeddings and word2vec for sentence embeddings.
Thereafter, they applied soft cosine similarity between sentences and BDI-II terms for each symptom
and performed weighted aggregation of these scores to compute the final scores and rank the sentences
in relation to symptoms of depression. A number of participating teams utilized LLMs in their systems
for eRisk 2023 in various tasks. For Task 1 in particular, the BLUE team [
        <xref ref-type="bibr" rid="ref10">10</xref>
        ] utilized ChatGPT to
enrich the BDI-II questionnaire terms, enhancing diversity. Then computed embeddings using two
Transformer models and performed semantic similarity with cosine similarity to ultimately rank the
sentences.
      </p>
      <p>
        Large Language Models are a relatively recent innovation in the field of Artificial Intelligence (AI) and
NLP; however, they already show great potential in many fields including mental health. Bakir Hadzic
et al. [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ] compared the eficacy of three popular LLMs: BERT, GPT-3.5 and GPT-4 for early detection
depression in textual data. The research was conducted across three datasets and revealed that GPT-4
significantly outperforms both BERT and GPT-3.5, demonstrating superior performance without prior
ifne-tuning. This suggests that GPT-4 could be a highly efective tool for early depression detection. The
study also highlights the potential of models like GPT-4 in mental health beyond depression, proposing
further development and fine-tuning of LLMs.
      </p>
    </sec>
    <sec id="sec-3">
      <title>3. Methodology</title>
      <p>
        We participated in Task 1: Search for symptoms of depression for the eRisk 2024 [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ] [
        <xref ref-type="bibr" rid="ref13">13</xref>
        ] lab of CLEF
2024. This is a continuation of the same task from CLEF eRisk 2023. The task consists of ranking
sentences from social media in terms of 21 symptoms of depression (Table 1) from the Beck Depression
Inventory–II (BDI-II) questionnaire. The BDI-II questionnaire is a self-report rating inventory and it
consists of 21 multiple-choice questions, each one relating to a specific symptom. Each question has
four possible answers from least to most severe, associated with a score from 0 to 3 respectively. The
scores assigned to each question are then summed to a total score with a maximum score of 63. High
total scores indicate a high chance of depressive symptoms.
      </p>
      <p>In more detail, each social media sentence should be assigned to the most relevant symptom out of
the 21. Subsequently, the sentences assigned to each symptom should be ordered in decreasing order
from the most to the least relevant. The relevant sentences should convey the author’s state concerning
the symptom, even if the sentiment is positive. For example, a sentence that expresses happiness should
be also considered relevant to the symptom of sadness. It is also emphasized that a sentence is only
relevant when it is solely about the author’s feelings related to the symptom and not the feelings of
other individuals. For example, a user post mentioning that the user’s sister is sad is not considered
relevant to sadness for that user because the user is not sad but their sister is.</p>
      <sec id="sec-3-1">
        <title>3.1. Dataset</title>
        <p>We were provided with two TREC formatted sentence-tagged datasets, one for training and one for
testing. Both datasets consist of unlabeled user sentences from Reddit posts. The training dataset
consists of last year’s data and the test set contains new data for this year’s eRisk that are to be used for
the evaluation of our systems. As presented in Table 2, the test data consist of a total of 15M sentences,
which is 11M more sentences than the dataset used in 2023, with approximately 18 words in a sentence
on average. We additionally created a small third dataset containing all symptoms and their respective
relevant answers from the BDI-II questionnaire. Examples for the symptoms of sadness and pessimism
are presented in Table 3.</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Ranking system</title>
        <p>The system we developed is illustrated in the flowchart of Figure 1. It involves multiple steps that we
will expand on below. These include text pre-processing, dataset cleaning by discarding sentences that
I do not feel sad I am not discouraged about my future
I feel sad much of the time I feel more discouraged about my future than I used to
I am sad all the time I do not expect things to work out for me</p>
        <p>I am so sad or unhappy that I can’t stand it I feel my future is hopeless and will only get worse
are not about the authors, sentence ranking using a pre-trained Transformer for sentence embeddings
and cosine similarity, and result refinement using GPT-4.</p>
        <p>For pre-processing, we translated all texts to English, turned all texts into lowercase, removed
punctuation and non-alphabetic symbols, and fixed word contractions. A sentence is considered
relevant only when it reflects the author’s state surrounding a symptom, consequently we conducted
keyword matching in order to only keep sentences that indicate that the author is talking about
themselves (I, me, mine, myself, mine, we, us, our, ourselves, ours). Following the removal of
sentences not containing any of the aforementioned keywords, we are confident that we have eliminated
a substantial portion of irrelevant texts, simultaneously reducing the computational workload from
15M to 11M sentences (Table 4).</p>
        <p>
          Due to the datasets provided being unlabeled, we focused on unsupervised methods for our systems.
We chose a pre-trained Transformer model to calculate the embeddings for the sentences and the
answers of each symptom. The Massive Text Embedding Benchmark (MTEB) [
          <xref ref-type="bibr" rid="ref14">14</xref>
          ] evaluates text
embeddings across a broad range of tasks and datasets to provide a comprehensive assessment of their
performance. It spans 8 embedding tasks, 58 datasets, and 112 languages and tests models to determine
their efectiveness. The MTEB Leaderboard 3 presents all tested models across all tasks, including text
ranking, along with numerous evaluation metrics. We considered models for the Retrieval and Reranking
tasks that were evaluated using NDCG@ (Normalized Discounted Gain at ) and MAP (Mean Average
Precision), respectively. Since we could already expect how some Transformer-based embeddings would
perform thanks to last year’s submissions, we explored new Transfomer models for this part of the task,
by excluding models that were involved in last year’s submissions. Based on the above criteria and the
need for a model that is as lightweight as possible without sacrificing substantial performance, we opted
for the bge-small-en-v1.54 Transformer model [
          <xref ref-type="bibr" rid="ref15">15</xref>
          ] that calculates 384-dimensional embeddings
and consists of 33M parameters.
        </p>
        <p>We calculated the cosine similarity score for each sentence paired with each answer for every
3https://huggingface.co/spaces/mteb/leaderboard
4https://huggingface.co/BAAI/bge-small-en-v1.5</p>
        <p>Sentence embedings</p>
        <p>Answer embeddings</p>
        <p>Text preprocess
Keyword matching
Cosine similarity</p>
        <p>Rank sentences</p>
        <p>Refinement with GPT-4
symptom. For every sentence, we kept the max similarity score out of the sentence-answer pairs for
each symptom and then assigned the sentence to the symptom with total max score. We then ranked
the sentences under every symptom based on the above score and kept the top 1,000 per symptom
resulting in a total of 21,000 ranked sentences from the initial corpus.</p>
        <p>Depression is a complex and delicate subject, hence we expect that our initial ranking using the
above method would be a decent but crude approximation to the task. To further refine our results,
we resorted to prompt engineering on top of GPT-4, which is considered as one of the state-of-the-art
LLMs. We used prompt engineering to discard any non-relevant sentences that were ranked high by the
previous steps of our system. Our goal was to use prompts asking GPT-4 to decide whether a sentence is
actually relevant (according to GPT-4) to the symptom. We first conducted experiments using ChatGPT
testing various candidate prompts comparing a shared prompt strategy (i.e. using the same prompt
for all symptoms) versus a symptom-specific prompt strategy. After our initial experimentation, we
decided that a symptom-specific strategy was more efective. All symptom-specific prompts followed
the same syntax for the sake of uniformity. Subsequently, we used the more powerful gpt4-turbo model
that we accessed via the OpenAI API5 for the final results. Our 21 prompts followed the subsequent
structure: “We will provide you with some sentences. Your task is to decide whether they are related to
symptom in a positive/negative sentiment or not”. Where we included each symptom and
its respective positive and negative sentiment. The detailed prompts are provided in Appendix A.</p>
        <p>Since positive feelings about a symptom are to be considered relevant as well, we made an efort to
include positive sentiment in the relevant sentences using our prompt. We removed all text that was
not considered relevant by GPT-4 resulting in 14,815 sentences, meaning that 6,185 sentences were
discarded as non-relevant. We submitted both the method without prompt engineering and with GPT-4
assessment in order to evaluate if GPT-4 improved the overall performance.</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Results</title>
      <p>We provided two runs with our results in the requested TREC format:
TransformerEmbeddings_CosineSimilarity contaning the results of our baseline method and
TransformerEmbeddings_CosineSimilarity_gpt with our final results using ranking refinement with GPT-4. In total, 9
teams participated in eRisk 2024 Task 1 with 29 submitted runs.</p>
      <p>eRisk selected a number of sentences from all teams’ submissions using top-k pooling. Then the
assessment was performed by human assessors who examined whether a sentence was correctly ranked
to a symptom or not. Two types of evaluations took place: a) a majority vote where the agreement of
the majority of the assessors is enough to label a ranking as correct (or not); b) a unanimity vote where
all of the assessors are required to agree. Five metrics were used for the evaluation of all submissions:
AP (Average Precision), MAP (Mean Average Precision), R-PREC (Recall Precision), P@10 (Precision at
10) and NDCG (Normalized Discounted Cumulative Gain).</p>
      <p>As presented in Tables 5 and 6, our systems demonstrated good performance across all metrics
in both the majority and the unanimity vote. Regarding the majority vote, we are approaching the
performance levels of the top performing teams across all metrics and we are above the mean and
median of total runs submitted by all teams. While our method with GPT-4 ranking refinement
TransformerEmbeddings_CosineSimilarity_gpt is improving the performance across all scores
except from NDCG.</p>
      <p>Concerning the unanimity vote, we received the best P@10 score of 0.833 for
TransformerEmbeddings_CosineSimilarity_gpt amongst all 29 runs of the participating teams. In terms of the rest of the
metrics, we are close to the best performing team, while our scores exceed both the mean and median
values of the scores of all teams runs once again. Consequently, the results indicate the strength of
both our baseline model and our refinement method. Our ranking refinement proposal turned out to
improve overall performance as there was an increase across all metrics with the exception of NDCG.</p>
    </sec>
    <sec id="sec-5">
      <title>5. Conclusion and future work</title>
      <p>In conclusion, based on the mean and median of the assessment scores of all teams, our methods are
competitive and exhibit potential for future research. Our proposed methodology consisted of a few
pre-processing and cleaning steps followed by a simple ranking using sentence embeddings, which
was further refined based on a prompt engineering strategy on top of GPT-4. However, there is room
for improvement in the scores by making enhancements in our methodology. One future step is to
experiment with various other prompting strategies that could be more efective in detecting relevant
and non-relevant sentences. Moreover, one could leverage publicly available depression-annotated
corpora to fine-tune GPT-4 so that it can better recognize the relevance of sentences to depression
symptoms. Finally, we could investigate leveraging LLMs to annotate parts of the dataset and use these
to train more accurate deep learning models in a supervised manner.</p>
    </sec>
    <sec id="sec-6">
      <title>Acknowledgments</title>
      <p>This work has been partially funded by the H2020 project “REBECCA: REsearch on BrEast Cancer
induced chronic conditions supported by Causal Analysis of multi-source data” under Grant Agreement
no. 965231 (https://rebeccaproject.eu/).</p>
    </sec>
    <sec id="sec-7">
      <title>A. GPT-4 Prompts</title>
      <p>Here we present the prompts used in this work in detail:
16. We will provide you with some sentences. Your task is to decide whether they are relevant to
experiencing (or not experiencing) changes in sleeping pattern.
17. We will provide you with some sentences. Your task is to decide whether they are relevant to
feeling (or not feeling) irritable.
18. We will provide you with some sentences. Your task is to decide whether they are relevant to
experiencing (or not experiencing) changes in appetite.
19. We will provide you with some sentences. Your task is to decide whether they are relevant to
having (or not having) dificulty concentrating.
20. We will provide you with some sentences. Your task is to decide whether they are relevant to
feeling (or not feeling) tired.
21. We will provide you with some sentences. Your task is to decide whether they are relevant to
losing (or not losing) interest in sex.</p>
    </sec>
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