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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Nature Commu-
nications</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.1038/s41467-022-34567-0</article-id>
      <title-group>
        <article-title>An argumentation interface to facilitate human-machine collaboration in scientific research: A preliminary exploration</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Yuanxi Fu</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Jodi Schneider</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>School of Information Sciences, University of Illinois at Urbana-Champaign</institution>
          ,
          <addr-line>501 E. Daniel Street, Champaign, IL 61820</addr-line>
          <country country="US">USA</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2022</year>
      </pub-date>
      <volume>13</volume>
      <issue>2022</issue>
      <abstract>
        <p>In today's increasingly data- and AI-driven scientific research enterprise, the division of labor between computational methods development and usage poses great risks of misuse. Moreover, flaws in a method can be uncovered years after the method's wide adoption, raising questions about how to share the information about uncovered lfaws with new generations of users in a timely manner. We propose an argumentation interface to meet these challenges. Using a toy example of choosing methods for ranking players in a chess tournament, we demonstrate how argumentation frameworks-which will form a key component in our argumentation interface-can be used to organize arguments about the choice of method. We lay out our plan to use the case of two prominent community detection algorithms to determine whether AFs are equally applicable to organizing arguments about choosing methods for scientific research tasks.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;argumentation in science</kwd>
        <kwd>argumentation interface</kwd>
        <kwd>computational methods</kwd>
        <kwd>argumentation frameworks</kwd>
        <kwd>community detection algorithms</kwd>
        <kwd>Louvain algorithm</kwd>
        <kwd>Leiden algorithm</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>Scientific research has an increasingly complex collaborative structure: collaborations can happen
between scientists and scientists, machines and machines, and scientists and machines. As a result,
disagreements and misunderstandings are likely to occur. Table 1 lists three scenarios familiar to
argumentation researchers and their analogues from scientific research.
Argumentation Research
A person accepts a belief that may do harm to them.</p>
      <p>Two parties locked in a disagreement due to ideological
diferences.</p>
      <p>A judge adjudicates a case.</p>
      <p>
        Scientific Research
An ecologist adopts an of-the-shelf network analysis
method that is inappropriate for their data [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ].
      </p>
      <p>
        An automated scientific discovery system encoded a
definition of “new material” that some scientists strongly disagree
with [
        <xref ref-type="bibr" rid="ref2 ref3">2, 3</xref>
        ].
      </p>
      <p>
        A computer program reconciles diferent data cleaning
operations carried out by two data scientists on the same dataset
and uses argumentation frameworks to decide which ones
to keep [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ].
      </p>
      <p>
        We are motivated by the first scientific research scenario from Table 1, where communication
challenges arise from the division of labor between the development and usage of a computational
method. Scientists who use a method, such as the ecologist in the scenario, often do not have the
background to fully comprehend the theoretical underpinnings of a method and, therefore, may misuse
the method (i.e., applying a network analysis method inappropriate for the data) [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. Also, flaws within
a method sometimes only surface years after the method’s wide adoption [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ], which creates two
problems: first, how to assess results produced without knowledge about the flaw [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ], and second, how
to share the information about uncovered flaws with new generations of users in a timely manner.
      </p>
      <p>We propose an application called an argumentation interface that mediates between a scientist and one
or several computational methods to improve the quality of the scientist’s application of computational
methods to their task. First, we outline the argumentation interface we envision. Second, we use a toy
example to illustrate a key component of the argumentation interface: using argumentation frameworks
to organize arguments about method choices. Finally, we describe our plans for future work.</p>
    </sec>
    <sec id="sec-2">
      <title>2. The argumentation interface</title>
      <p>
        We propose an argumentation interface to improve the quality of a scientist’s application of
computational methods to their task (Figure 1). The argumentation interface mediates between a pool of
computational methods and a scientist. For a given method, the interface retrieves relevant
information about it (1) from the documents describing the computational method and (2) from the scientific
literature where the utilization and critiques of the method may be described. It also converses with
the scientist to learn about the characteristics of their task. Ultimately, the argumentation interface
assembles all the information about the method and the task into an argumentation framework (AF),
visualize the AF (e.g., [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]), and provide suggestions about the choice of method to the researcher.
      </p>
      <p>
        So far, we envision three types of nodes in the AF: method choice nodes, method merit/flaw nodes,
and task condition nodes. Method choice nodes represent arguments about method choices, for instance,
Task X should use Method A, Task X should use Method B, Task X should use Method C, etc. Method merit
node represent merits of the method over other choices. Method flaw nodes represent flaws in methods
either described as limitations by the method developers or discovered by others when methods are in
use. These nodes can by placed in supporting or attacking relationships with method choice nodes.
The third type of node considers a task’s conditions. For instance, even though a method contains a
lfaw but under certain conditions, this flaw does not materialize into wrong scientific conclusions [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ].
Thus, the node representing a task-specific argument such as “Flaw F will not materialize since the task
is ...” is a task condition node and can be placed in an attacking relationship with the method flaw node
representing the Flaw F.
      </p>
    </sec>
    <sec id="sec-3">
      <title>3. Applying abstract argumentation framework to organize arguments about method choices: a toy example</title>
      <p>
        Now we provide a toy example to illustrate how the abstract argumentation framework [
        <xref ref-type="bibr" rid="ref10">10</xref>
        ], the most
elementary argumentation framework, can be used to organize arguments about method choices. The
example is derived from a historical account of method innovation in ranking players in a type of chess
tournament popular in the late 19th century [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ].
      </p>
      <sec id="sec-3-1">
        <title>3.1. Landau’s PageRank</title>
        <p>In 1895, German mathematician Edmund Landau proposed a new method to rank players in a round
robin chess tournament which requires each pair of players to face of. Traditionally, a player’s final
score was calculated by (1) giving 1 point to each winner, 0 to each loser, and 1/2 to each player in a
draw and (2) summing up all points. Landau sensed a fairness issue with this scoring system: players
who won against stronger players should get more points than those who won against weaker players.
He proposed “relative Wertbemessung” (relative score) as an alternative, which in mathematical essence
is the same as Page and Brin’s famous PageRank algorithm for ranking webpages. Thus, we will refer
to it as “Landau’s PageRank”. However, Landau also pointed out that his method, although fairer in
evaluating players, introduces an unfortunate incentive for players to strategically play NOT to win.
He used a three-player scenario to illustrate his concern, where a player improves their final standing
by not winning certain games.</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Applying the abstract argumentation framework</title>
        <p>
          The story behind Landau’s PageRank was described by Sinn and Zeigler [
          <xref ref-type="bibr" rid="ref11">11</xref>
          ]. We organized the
arguments about choosing between the traditional scoring system and Landau’s PageRank, which
can be found in pages 1 to 3 of [
          <xref ref-type="bibr" rid="ref11">11</xref>
          ], into an abstract argument framework (Figure 2). We also added
one argument of our own (Argument E). Landau’s concern about manipulation was illustrated by a
three-player scenario. However, when the number of players becomes suficiently large, it will be
dificult to strategically play not to win, because (1) A player cannot always control the outcome of the
games even if they do not try to win, and (2) A player must also consider the outcomes of other games,
which is likely too complex for humans.
        </p>
        <p>Figure 2 shows one solution of the argument framework matching our preferences. Let’s assume that
we are dealing with a round robin tournament of 30 players, and we accept argument E, and we also
agree with Landau’s concern about fairness (i.e., accepting Argument C). In this solution, we choose
Landau’s PageRank as our method for ranking players (Argument B).</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Future Work</title>
      <p>
        Choosing a computational method for a research task is more complex than the toy example we have
shown. Our next step is to determine whether AFs are equally applicable to organizing arguments
about choosing methods for scientific research tasks. To test this, we will use the case of two prominent
community detection algorithms, the Louvain algorithm [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ] and the Leiden algorithm [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ].
      </p>
      <p>
        The Louvain algorithm was proposed in 2008 by Blondel et al. [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ] and has received more than 11000
citations as of August 2024. The Leiden algorithm, proposed in 2019 by Traag et al. [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ], presented a
necessary update due to a significant flaw uncovered in the Louvain algorithm: It can produce arbitrary
and disconnected “communities”. As of August 2024, the Traag et al., 2019 paper has received more
than 1700 citations. We refer to these Blondel et al., 2008 as “the Louvain paper” and Traag et al., 2019
as “the Leiden paper”.
      </p>
      <p>We retrieved all citations of the Louvain paper and the Leiden paper from the Web of Science database
on August 21, 2024. Among them, 483 cited both papers, which confirms these authors’ awareness of
both algorithms. We will use this corpus of 483 publications to study the arguments about choosing
between the two methods. We will collect arguments for method merit/flaw nodes from the corpus.
We will also seek arguments for task condition nodes. For instance, we already know that the Louvain
algorithm has a significant flaw according to the Leiden paper, but we do not know whether this flaw
deters specific applications of the Louvain algorithm. We also need to find out whether Louvain has
specific merits that warrant its use instead of Leiden. We will answer the questions through the analysis
of the corpus.</p>
      <p>
        Once we have a collection of method merit/flaw nodes and task condition nodes, we will select a
few popular research tasks from the corpus. One such task we discovered is detecting spatial gene
expression patterns [
        <xref ref-type="bibr" rid="ref13 ref14 ref15">13, 14, 15</xref>
        ]. We will use the method merit/flaw nodes and task condition nodes to
construct AFs for these research tasks. We will present the resulting AFs and their solutions to domain
experts for evaluation.
      </p>
    </sec>
    <sec id="sec-5">
      <title>5. Conclusions</title>
      <p>We propose an application called an argumentation interface that mediates between a scientist and one
or several computational methods to improve the quality of the scientist’s application of computational
methods to their task. We use a toy example of choosing methods for ranking players in a chess
tournament to demonstrate how argumentation frameworks can be used to organize arguments about
method choices, which will form a key component in our argumentation interface. We lay out a plan to
use a case of two prominent community detection algorithms to determine whether AFs are equally
applicable to organizing arguments about choosing methods for scientific research tasks.
Ideation of this work came from research supported by Alfred P. Sloan Foundation (G-2020-12623;
G2022-19409). YF thanks Scott Jacobs and Sally Jackson for their introductory courses on argumentation
theories that lay the foundation for this work. Thanks to Michael Twidale and Heng Zheng for comments.
Thanks to Bertram Ludäscher for providing the essential Landau’s PageRank case.</p>
    </sec>
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