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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>P. V. d. C. Souza);</journal-title>
      </journal-title-group>
      <issn pub-type="ppub">1613-0073</issn>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>Hospitals⋆</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Paulo Vitor de Campos Souza</string-name>
          <email>pdecampossouza@fbk.eu</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Mauro Dragoni</string-name>
          <email>dragoni@fbk.eu</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Workshop</string-name>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Fondazione Bruno Kessler</institution>
          ,
          <addr-line>Via Sommarive 18 - 38123 Trento (TN)</addr-line>
          ,
          <country country="IT">Italy</country>
        </aff>
      </contrib-group>
      <volume>000</volume>
      <fpage>0</fpage>
      <lpage>0003</lpage>
      <abstract>
        <p>Accurate identification of patient emergency states in emergency rooms is vital for delivering timely and appropriate medical intervention. This paper presents a comprehensive approach using a dataset from a Northern Italian hospital to predict patient urgency levels with machine learning algorithms. We processed and analyzed the data through feature selection techniques, feature importance analysis, and interpretability methods, focusing on the dataset dimensions. Our tests resulted in accuracy exceeding 95% in three machine learning algorithms, demonstrating the feasibility of developing an intelligent computerized system capable of predicting emergency states in an emergency room setting. These findings suggest that integrating advanced data analytics can significantly enhance patient triage and hospital resource planning.</p>
      </abstract>
      <kwd-group>
        <kwd>Emergency classification</kwd>
        <kwd>Intelligent systems</kwd>
        <kwd>Pattern classification</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>The identification of patient urgency levels in emergency departments (EDs) is crucial for ensuring
timely and appropriate care. The Manchester Triage System (MTS) is commonly employed to categorize
patients based on their level of urgency, utilizing a color-coded protocol to prioritize patient care
efectively. This systematic approach aids in managing patient flow and ensuring that those who
require immediate attention receive it without unnecessary delay. The implementation of the MTS has
significantly contributed to the optimization of emergency department operations, enhancing patient
outcomes and operational eficiency.</p>
      <p>
        Recent advancements in artificial intelligence (AI), machine learning (ML), and data mining have
shown promising potential in augmenting traditional triage protocols like the MTS. For example, Lee et
al. [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] developed an AI model using neural networks and machine learning to predict hospital admission
for urgent patients, demonstrating the potential for streamlining ED operations with minimal variables.
While, Mutegeki et al. [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] utilized machine learning classification algorithms to predict the Emergency
Severity Index of patients based on their medical data, demonstrating the utility of AI for enhancing
triage decisions.
      </p>
      <p>In our paper, we explore the application of diferent machine learning and data mining techniques to
discover patterns in a real-world dataset of hospital visits gathered from hospitals in Northern Italy.
Traditional machine learning models will be employed to analyze this dataset, which is unprecedented
in its reflection of the hospital’s routine in a tangible, real-world context. The contribution of this
paper is twofold. Firstly, it provides a critical discourse on the dimensions impacting the screening of
individuals in emergency scenarios. By applying a fusion of data science, machine learning, and data
mining techniques, we unravel patterns within a genuine dataset of hospital admissions, showcasing the
potential of these approaches to assist emergency room (ER) operations. Secondly, this work endeavors</p>
      <p>CEUR</p>
      <p>ceur-ws.org
to bridge the gap between theoretical models and practical applications, fostering advancements that
could underpin smarter, data-driven decisions in emergency care settings.</p>
      <p>The remainder of this paper is organized as follows. Section 2 provides a comprehensive literature
review, laying the groundwork for the applied methodologies and situating our work within the existing
body of research. Section 3 details the dataset employed in this study, including the preprocessing steps
and preparation procedures essential for the subsequent analyses. In Section 4, we delve into the testing
methodologies and discuss the results obtained from the machine learning models. Finally, Section 5
concludes the paper with a summary of our findings and an outline of potential avenues for future
research.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Background and Related Work</title>
      <p>In this Section, we present the main concepts about the emergency protocol in hospitals and some
state-of-the-art machine learning techniques for solving problems in this context.</p>
      <sec id="sec-2-1">
        <title>2.1. Emergency Triage System</title>
        <p>
          The Manchester Triage System (MTS) is a pivotal methodology in EDs for categorizing patient urgency
utilizing a five-level urgency scale to ensure patients receive care promptly based on the severity of
their condition. The system is designed around a series of flowcharts, each corresponding to diferent
presenting complaints, while leading triage nurses through a series of discriminators to assign an
appropriate urgency level. This methodology facilitates a more organized patient flow within EDs,
aiming to reduce wait times and prioritize care for those most in need [
          <xref ref-type="bibr" rid="ref3">3</xref>
          ].
        </p>
        <p>
          The MTS’s robust framework enhances its capability to extend beyond mere prioritization, ofering
insights into patient outcomes such as hospital admission rates and mortality. Studies have demonstrated
the system’s efectiveness in distinguishing between high and low-risk patients, proving its value not
only as a triage tool but also as a predictive model for patient disposition [
          <xref ref-type="bibr" rid="ref3">3</xref>
          ]. Moreover, the MTS’s
adaptability to various healthcare settings underscores its utility in improving emergency care delivery
worldwide.
        </p>
        <p>To illustrate the classifications within the MTS, Table 1 summarizes the color-coded urgency levels
and their meanings.</p>
        <p>Color Code
Red
Orange
White
Green
Blue</p>
        <p>Meaning
Immediate attention required
Very urgent
Urgent
Standard</p>
        <p>Non-urgent</p>
      </sec>
      <sec id="sec-2-2">
        <title>2.2. Machine Learning Models and Datasets in Emergency Detection Using the</title>
      </sec>
      <sec id="sec-2-3">
        <title>Manchester Triage System</title>
        <p>A critical component of ED eficiency is the accurate triage of patients based on urgency, for which the
MTS is widely used. Recent studies have integrated ML techniques to enhance the predictive power of
MTS, improving patient outcomes and resource allocation.</p>
        <p>
          Roquette et al. (2020) explored deep neural networks (DNNs) combined with triage textual data
to predict ED admissions, emphasizing the importance of text processing for enhanced prediction
accuracy [
          <xref ref-type="bibr" rid="ref4">4</xref>
          ]. Zachariasse et al. (2016) assessed the safety of MTS in pediatric care, identifying risk
factors for undertriage and suggesting modifications for improvement [
          <xref ref-type="bibr" rid="ref5">5</xref>
          ]. Seiger et al. (2014) examined
modifications to MTS and the inclusion of abnormal vital signs in pediatric EDs across multiple centers,
aiming for reduced incorrect assignments [
          <xref ref-type="bibr" rid="ref6">6</xref>
          ]. Azeredo et al. (2015) reviewed the eficacy of MTS for risk
classification, pointing out its validity across various patient demographics but also its tendency towards
sub-triage [
          <xref ref-type="bibr" rid="ref7">7</xref>
          ]. Zachariasse et al. (2017) evaluated MTS’s validity across diferent emergency care settings,
noting moderate to good performance with lower efectiveness in young and elderly patients [
          <xref ref-type="bibr" rid="ref8">8</xref>
          ]. Santos
et al. (2013) investigated MTS version II for resource utilization, indicating improvements, especially in
surgical specialties [
          <xref ref-type="bibr" rid="ref9">9</xref>
          ].
        </p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>3. Dataset: Emergency protocol in an Italian hospital</title>
      <p>This section outlines the methodology adopted to prepare the dataset we obtained from a Northern
Italian hospital and that has been used for our investigation. The dataset comprises various dimensions,
including patient codes, gender, date of birth, residency, age, mode of arrival, primary problem, diagnosis
codes, and the urgency of care required. The objective was to predict the state of emergency from these
features. The methodology employed is described step by step below:</p>
      <sec id="sec-3-1">
        <title>3.1. Data Cleaning and Preprocessing</title>
        <p>Data cleaning and preprocessing are pivotal initial steps to ensure the quality and coherence of the
dataset for subsequent analysis. This process lays the groundwork for a robust predictive model by
enhancing data integrity and relevance.</p>
        <p>The dataset, originating from the automated system of a hospital in Northern Italy, comprises 582
instances and 18 features with approximately 17% missing data. To enhance data quality and prepare
for analysis, features, and samples with missing values were meticulously identified and pruned from
the dataset.</p>
        <p>Conforming to patient privacy regulations, any variables that could potentially lead to patient
identification were rigorously excluded. In alignment with privacy considerations, the following
identifiers were removed: Encounter ID, Fiscal Code, and Birth Date. Moreover, to establish an unbiased
foundation for model comparison against human-assigned urgency levels, the Urgency Triage dimension
was omitted to prevent it from influencing the model’s prediction of the final emergency state. Similarly,
Outcome and Send Mode, which relate to the patient’s ultimate stage in the care pathway, were excluded,
as their inclusion post-triage could introduce post-hoc bias into the predictive model. The Diagnose
Code was also excluded, as it is typically generated after the triage process and does not reflect the
initial presentation.</p>
        <p>The remaining dimensions retained for analysis include Commune Residence, Age, Arrival Mode,
and Main Problem (1) and (2). These dimensions were selected for their relevance to the patient’s initial
clinical presentation and their potential utility in predicting the appropriate level of emergency care.</p>
        <p>By concentrating on these dimensions, we aim to build a predictive model that mirrors the initial
assessment of a patient’s emergency state based on unbiased, non-identifiable clinical features, thereby
allowing a direct and fair comparison with the hospital’s triage outcomes.</p>
        <p>After the data pre-treatment procedures, 5 dimensions remained, which are shown in Figure 1.</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Target Variable Definition</title>
        <p>The core of an efective triage system is its ability to quickly and accurately determine a patient’s
condition urgency, guiding care prioritization. Our research utilizes data mining to identify urgency as
the key target variable, crucial for the patient care process. This variable, hereafter called Appropriateness
Outcome, stems from a thorough triage evaluation of the patient’s condition severity and immediacy. It
is essential for training algorithms to accurately predict case urgency, influencing critical decisions like
resource allocation, tending to immediate medical needs, and managing patient flow in emergency care.
Figure 2 graphically shows the relationship between age and emergency classification.</p>
        <p>The complexity and insight of the relationship between the target variable and input features, such as
presenting symptoms, age, and arrival mode, directly influence the assigned urgency level of a patient’s
case. For example, specific symptoms may indicate life-threatening conditions requiring immediate
care, while others are less severe. Age reflects a patient’s vulnerability to certain emergencies and
complications, afecting urgency classification. Similarly, arrival mode suggests the severity of the
condition, with ambulance arrivals often indicating a need for urgent care. This understanding, captured
in Figure 3, enables future models to replicate the nuanced decision-making of human-led triage. The
model’s predictive accuracy depends on its ability to understand these relationships, aiming to match
or exceed human judgment in triage scenarios. Figure 3 illustrates the feature importance ranking, as
determined by various statistical methods for feature selection, enhancing the model’s efectiveness in
emergency assessments.</p>
        <p>Appropriateness Outcome works not simply as a categorical endpoint, but as a vital gauge for evaluating
the eficacy and quality of emergency medical services. Through our model, we endeavor to refine this
gauge, harnessing the subtleties of machine learning to improve the triage process and enhance the
delivery of emergency healthcare.</p>
      </sec>
      <sec id="sec-3-3">
        <title>3.3. Feature Selection</title>
        <p>Feature selection is a critical step in the development of predictive models, aimed at eliminating
redundant or irrelevant features that could potentially degrade model performance. By narrowing down
the dataset to the most informative attributes, we ensure that the models are trained on data that most
significantly influence the prediction of the emergency state.</p>
        <p>
          Our process for feature selection was informed by a thorough analysis of feature correlations, as
illustrated in Figure 3. From left to right, the statistical techniques employed are as follows [
          <xref ref-type="bibr" rid="ref10">10</xref>
          ]:
• Information Gain: quantifies how much a feature decreases uncertainty when predicting the
target variable.
• Gain Ratio: adjusts information gain for feature bias, factoring in the number and size of branches
it creates.
• Gini Index: measures a feature’s ability to discriminate between classes; lower values indicate
greater purity.
• ANOVA: determines if the mean of the target variable significantly difers across groups defined
by a feature.
• Chi-Squared ( 2): assesses the strength of association between features and the target variable;
higher values mean greater significance.
• Relief: weights features based on their capability to diferentiate between similar instances of
varying classes.
• FCBF: identifies the most predictive features that are correlated with the target class while
minimizing redundancy.
        </p>
        <p>In Figure 3, Main Problem (2) and Main Problem (1) are evaluated similarly across most techniques,
indicating their significant roles in predicting the outcome. These problems are related to the first
symptom of the patient (pain, cut, fever, cold, etc). Age also shows a strong presence, especially
notable in the Information Gain and Chi-Squared evaluations, which suggests its critical influence
in emergencies. Municipality of Residence demonstrates moderate relevance, whereas Arrival Mode
stands out particularly in the ANOVA and Chi-Squared assessments, reflecting its potential impact on
the urgency classification.</p>
        <p>Each statistical technique ofers a unique perspective on feature relevance, and collectively they
provide a comprehensive understanding of which features are most influential. By analyzing these
rankings, we can strategically select a combination of features that will empower our predictive model
to make accurate assessments reflective of real-world triage situations.</p>
        <p>This feature selection process, therefore, is not just a step towards model optimization —it is an efort
to capture the essence of practical emergency assessment, ensuring that our predictive system can
operate with the highest degree of reliability and validity.</p>
        <p>The analysis of the role of Municipality of Residence in predicting urgency in an Italian hospital
context revealed methodological variations in its correlation with the Appropriateness Outcome. All
dimensions were retained for comprehensive future analyses.</p>
        <p>Figure 4 illustrates a violin plot showing how diferent levels of urgency, represented by specific
colors, are distributed among patients from various municipalities. The width of the violin indicates
the density of cases at each level of urgency, while the central point and line represent the median and
interquartile ranges, respectively. This visualization aids in identifying patterns of emergency case
distribution by locality, which is crucial for predicting emergency care demands and planning resources
efectively. The relationship between the municipality of residence and the Appropriateness Outcome
is essential for feature selection and maintaining the predictive accuracy of the triage system when
applied across diferent demographic and geographic profiles.</p>
        <p>By judiciously selecting features, we can refine the models’ focus, directing computational power
toward analyzing data points that have a substantive impact on emergency care outcomes. Such a
practice not only streamlines the modeling process but also contributes to the generalizability of the
model, ensuring that its applications extend beyond the immediate dataset to inform wider regional
healthcare strategies.</p>
        <p>Through this feature selection process, we aim to construct a model that embodies the delicate balance
between the inclusivity of relevant data and the exclusivity of noise, thereby maximizing predictive
accuracy and reliability in real-world emergency triage situations. To incorporate categorical variables
into machine learning models, they must be transformed into a numerical format. This involved:
• Ordinal Encoding: For categories with inherent order, ordinal encoding assigns each category a
unique number, preserving the hierarchical structure important for predictions. This is
theoretically represented as a mapping function  ∶  → ℝ , where each category   in the set  is given a
unique ordinal number.
• Numeric Feature Handling: Numeric features are kept as-is to maintain their original scale
and distribution, avoiding potential biases from data normalization.
• Target Variable Encoding: The categorical outcome variable remains in its categorical form to
keep classification outcomes clear and prevent introducing artificial order.</p>
        <p>In essence, these methods ensure the variables retain their original meaning and relevance, crucial for
creating interpretable and accurate models. An example visualization of the dataset after transformation
is shown in Figure 5.</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Results and Discussion</title>
      <sec id="sec-4-1">
        <title>4.1. Experimental Models</title>
        <p>In the experimental phase, we tested various ML models for classification and pattern recognition:</p>
        <p>
          In our study, we explored a variety of ML models for classification tasks. Random Forest constructs
multiple decision trees to enhance prediction accuracy through ensemble techniques [
          <xref ref-type="bibr" rid="ref11">11</xref>
          ]. Naive Bayes
utilizes Bayes’ theorem with strong independence assumptions, proving eficient in handling
highdimensional datasets [
          <xref ref-type="bibr" rid="ref12">12</xref>
          ]. Neural Networks model complex relationships through interconnected
neurons [13]. CN2 Rule Induction generates interpretable if-then rules [14]. AdaBoost improves
classification strength by sequentially focusing on misclassified instances [ 15]. SVM operates efectively
in high-dimensional spaces by identifying optimal separating hyperplanes [16]. Lastly, Stochastic
Gradient Descent facilitates eficient optimization in large-scale learning problems [ 17]. We assessed
our models’ performance using Confusion Matrices and Lift Curves, combining them with
crossvalidation (k=5) to establish a comprehensive framework for evaluating predictive accuracy and model
behavior on the dataset, as detailed in Table 2.
        </p>
        <p>Random Forest, CN2 Rule Induction, and AdaBoost demonstrated superior performance in
emergency prediction tests, with Random Forest achieving an AUC of 0.992. These models showed high
precision and recall, efectively identifying true positives while minimizing false positives and negatives,
indicating their potential utility in clinical decision support systems. The Random Forest and AdaBoost
models showcase exemplary performance with classification accuracies of 0.997 and 0.988 respectively,
indicating their robustness and reliability in predicting emergency states. as highlighted in Figure 6.</p>
        <p>Their confusion matrices are presented in Figure 7. The confusion matrices for AdaBoost and Random
Tree (Figure 7 indicate high accuracy in true positive rates, particularly in the ORANGE, BLUE, and
RED classes for AdaBoost, and in the ORANGE and RED classes for Random Tree, evidencing their
strength in correctly classifying the majority of cases.</p>
        <p>The Tree algorithm’s decision structure (Figure 8) reveals key paths to identifying the most complex
RED cases: one significant pathway emerges when the Age is greater than 39 and the Main Problem
is identified as critical, leading to a substantial proportion of RED outcomes. Another notable route
is for patients over 73 years old, where the Main Problem significantly influences the likelihood of a
RED classification, demonstrating the algorithm’s capacity to discern intricate patterns that signal high
emergency levels.</p>
        <p>Using SHAP values (Fig. 9) and Random Forest feature importance analysis, Figure 10, reveals the
impact of various features on emergency prediction, highlighting the significant roles of Age, Main
Problem (1), and Main Problem (2). While showing Municipality of Residence and Arrival Mode as
secondary and variable factors, respectively. This comprehensive analysis aids in refining ER triage and
intervention strategies.</p>
        <p>Age and Main Problem are identified as primary determinants of emergency case urgency, with
Age exhibiting varied impacts and Main Problem a consistent, significant influence. Municipality of
Residence and Arrival Mode ofer additional context but exert a lesser and less variable influence on
model predictions. In Fig. 11, the graphical representation of the Random Forest model shows terminal
nodes representing the most critical (red) and non-critical (blue) cases at the extremes of decision tree
branches, demonstrating the model’s efectiveness in diferentiating emergency levels, vital for ER
decision-making and resource allocation.</p>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>5. Conclusion</title>
      <p>This paper proposed the analysis and development of a computerized system capable of predicting
emergencies in ERs based on data from a hospital in Northern Italy. Our methodology encompassed data
preprocessing, feature engineering, and the application of machine learning models which delivered
satisfactory and interpretable results. The high predictive performance of our models ensured relevant
insights into the nature of emergencies, ofering valuable enhancements to the MTS protocol. Future
work may extend predictions to other target variables, such as patient outcomes post-triage, to enable
hospitals to better plan space and workforce allocation. The insights derived from our study afirm the
transformative potential of AI in optimizing ER operations and patient care.
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[14] P. Clark, T. Niblett, The cn2 induction algorithm, Machine learning 3 (1989) 261–283.
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[16] C. Cortes, V. Vapnik, Support-vector networks, Machine learning 20 (1995) 273–297.
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