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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Optimization of medical logistics with bee colony algorithms in emergency, military conflict and post-war remediation settings ⋆</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Tetiana</string-name>
          <email>tetiana.cherniavska@konin.edu.pl</email>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Bohdan</string-name>
          <email>bohdan.cherniavskyi@konin.edu.pl</email>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Tamar</string-name>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Sharashenidze</string-name>
          <email>sharashenidzealexandre11@gtu.ge</email>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Magda Tortladze</string-name>
          <email>magda.tar@gtu.ge</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Maka Buleishvili</string-name>
          <email>makabule66@yahoo.com</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Caucasus International University</institution>
          ,
          <addr-line>73 Chargali St., Tbilisi , 0141</addr-line>
          ,
          <country country="GE">Georgia</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>European University</institution>
          ,
          <addr-line>D. Guramushvili Ave. 72, Tbilisi, 0141</addr-line>
          ,
          <country country="GE">Georgia</country>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>Georgian Technical University</institution>
          ,
          <addr-line>M. Kostava St. 77, Tbilisi, 0160</addr-line>
          ,
          <country country="GE">Georgia</country>
        </aff>
        <aff id="aff3">
          <label>3</label>
          <institution>Tbilisi State Medical University</institution>
          ,
          <addr-line>33 Vazha Pshavela Ave, Tbilisi, 0186</addr-line>
          ,
          <country country="GE">Georgia</country>
        </aff>
        <aff id="aff4">
          <label>4</label>
          <institution>University of Applied Sciences in Konin</institution>
          ,
          <addr-line>Przyjażni 1, Konin, 62-510</addr-line>
          ,
          <country country="PL">Poland</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>The article discusses the application of bio-inspired Bee Colony Algorithm (ABC) in medical logistics, which is an important and promising direction in the conditions of the increasing scale and complexity of various risks and threats. The algorithm's ability to effectively adapt to changes, optimize resource use, and provide decentralized management makes it an essential tool for solving emergency medical care problem, mitigating military conflicts and natural disasters. The ABC can be effectively integrated with modern information technologies, such as Internet of Things (IoT) monitoring systems and autonomous drones, significantly multiplying their combined use. These technologies enable real-time data collection on the data on the state of damaged infrastructure, the nature and extent of damage, an analysis of medical resources requirements, and the optimal delivery of medical care. Combined with the ABC algorithm, such integration can significantly improve the efficiency and effectiveness of management decisions made in extreme complexity and uncertainty conditions. In modern realities, where traditional methods cannot cope with the dynamics and scale of the above-described problems, bio-inspired algorithms are an effective tool for increasing the flexibility and adaptability of the healthcare system, which can be used in international practice. The authors analyzed the feasibility of implementing the ABC to solve the logistical challenges of providing emergency medical care in military conflict zones and during emergencies. They prioritized the prompt delivery of medical resources such as medications, equipment, and medical personnel to areas needing assistance. The article thoroughly examines the practical aspects of using an integrated optimization algorithm, based on examples of recent military conflicts and natural disasters in conditions where delivery routes and needs for medical care can change quickly, and the number of available resources can vary. The authors are focused on analyzing the advantages of the proposed integrated optimization algorithm for emergency medical logistics. They revealed that traditional planning approaches cannot adapt quickly to changes in resource delivery parameters. This study is comprehensive and encompasses a wide range of tasks. It includes organizing emergency medical care logistics during emergencies and military conflicts, as well as implementing post-war remediation tasks using the ABC approach in conjunction with modern IT solutions and IoT.</p>
      </abstract>
      <kwd-group>
        <kwd>Alexander</kwd>
        <kwd>eol&gt;Bee Colony Algorithm (ABC)</kwd>
        <kwd>Internet of Things (IoT)</kwd>
        <kwd>IT solutions</kwd>
        <kwd>emergency medical logistics</kwd>
        <kwd>emergency medical care</kwd>
        <kwd>remediation</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>1,†,</p>
    </sec>
    <sec id="sec-2">
      <title>1. Introduction</title>
      <p>0000-0002-4729-2157 (T. Cherniavska); 0000-0001-9174-6139 (B. Cherniavskyi); 0000-0003-1618-5276 (T. Sanikidze);
0009-0008-8289-1850 (A. Sharashenidze); 0009-0009-4340-499X (M. Tortladze); 0009-0004-2657-8473 (M. Buleishvili)</p>
      <p>In recent years, the world has been facing an increasing number of crises, such as military conflicts,
natural disasters and environmental catastrophes, which require healthcare systems to provide
effective and prompt solutions to provide medical care. These threats are characterized by a high
degree of complexity, unpredictability and scale, which requires fundamentally new solutions in the
medical field, especially at the emergency response stage when such a situation occurs, and then at
the stage of remediation from its consequences. Advanced information technologies, particularly
bio-inspired optimization algorithms like the artificial bee colony (ABC) algorithm, integrated with
advanced IT technologies, play a crucial role in managing complex systems such as emergency
medical logistics. These algorithms excel at solving optimization problems in conditions involving
multitasking and high uncertainty. The ABCs can effectively optimize delivery routes and resource
allocation based on real data obtained using IoT devices and monitoring systems. This is critical, for
example, in conditions of destroyed infrastructure, a prompt search for alternative routes for
essential resource delivery can save numerous lives.</p>
      <p>
        Using bio-inspired technologies not only in emergencies but also in military activities, as well as
in post-war remediation. Our in-depth study of this range of issues was also inspired by the
publication of Javad Behnamyan and Zikha Kiani Untirta [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] in the context of expanding the scope
of application of fairly new, but already proven biotechnologies, such as ABC. In addition, the
research work of Jinbao et al. (2023) served as the basis of our ideas concerning optimizing
emergency medical logistics.
      </p>
      <p>The research is centered around the different metaheuristic algorithms to optimize emergency
logistics. The main focus is on algorithms that can find solutions for problems with multiple
constraints, which are essential for effectively managing medical logistics during crises.</p>
      <p>
        These ideas became the key focus of our research into the feasibility of applying bio-inspired
technologies not only in emergency situations but also in military operations and post-war
remediation. Our in-depth study of these issues was also inspired by the publication of Javad
Behnamian and Zikha Kiani Untirta [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ], which explored the expansion of relatively new but already
proven biotechnologies, such as ABC (Artificial Bee Colony). Furthermore, the research by Jinbao
L. et al. (2023) played a significant role in substantiating our ideas in the context of optimizing
emergency medical logistics. Their work focuses on using various metaheuristic algorithms to
optimize logistics in unforeseen circumstances, particularly emphasizing algorithms that solve
multi-constraint problems crucial for effective medical logistics in crisis scenarios.
      </p>
      <p>
        Considering all factors affecting emergency medical logistics is fundamentally important. Thus,
a study by Chinese scientists indicates the need to consider the multi-cyclical nature of the supply
of emergency medical resources in uncertain conditions with limited transportation capabilities. [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ].
Research on multi-purpose supply management of relief supplies led us to believe that our study
would be highly relevant and significant in the recovery efforts in active military areas affected by
various weapons [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ]. To study the management aspects of optimizing emergency medical logistics,
we analyzed the study of a bio-objective model for planning logistics services in emergencies based
on uncertain conditions [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ].
      </p>
      <p>
        Effective emergency medical care management process largely depends on the rational
distribution of specific medical supplies. We adopted and applied the principles of the distribution
of essential supplies during the COVID-19 pandemic based on cloud computing, described by [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ].
Bingqing Zhang's article is devoted to studying the various aspects of optimizing the emergency
logistics network based on a cloud platform, which expanded our understanding of the possibilities
of integrating the ABC optimization algorithm with advanced computer technologies [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]. We
explored the potential use of drones and data satellites to optimize delivery routes and minimize
risks in medical logistics. We concluded that their integration into the ABC optimization model can
greatly reduce the speed of delivering the necessary resources to the places of their urgent need.
The idea was inspired by a team of researchers focusing on developing an algorithm to optimize an
adaptive ant colony for real-time logistics functions in emergency delivery.[
        <xref ref-type="bibr" rid="ref9">9</xref>
        ].
      </p>
      <p>
        Crisis logistics largely depend on weather conditions. Our study applied the adapted ideas of
Bogdanova L. on emergency logistics management in crisis weather conditions [
        <xref ref-type="bibr" rid="ref10">10</xref>
        ]. The author's
scientific views are completely consistent with our position that the success of logistics operations
depends, first of all, on making informed decisions that should take into account various factors,
including weather conditions, the nature of the crisis, its causes, the number of affected people, the
nature of injuries, etc. Particular attention is focused on the role and importance of IT systems in
database updating. The analyzed above publications highlight the significance of effectively
managing medical logistics during extreme situations. They stress the need for comprehensive
management of this process, specifically emphasizing the importance of preparedness to minimize
losses and save human lives.
      </p>
    </sec>
    <sec id="sec-3">
      <title>2. Materials and methods</title>
      <p>The topic of this study is transdisciplinary and includes intersections with several disciplines: public
health and healthcare, healthcare economics, logistics and supply chain management, algorithmic
optimization, big data and the IoT, bioinformatics, and machine learning. In this context, the key
methodological approaches that form the “core” and the set of first-order scientific methods of our
transdisciplinary research are the optimization ABC – the core of the model, and together with it –
the systemic, complex, synergetic, adaptive, situational approaches, optimization modelling. Each
methodological approach plays a unique role, complementing others to ensure the integrity and
depth of scientific analysis.</p>
      <p>The ABC is bio-inspired and focused on the bee behavior principles methodological solution,
providing a core of innovative model adapting to environmental changes, enabling quick resource
redirection and plan adjustments. Artificial Bee Colony Optimization is a polynomial heuristic
algorithm widely used to solve optimization problems in computer science and operations research.
This algorithm is a stochastic bionic algorithm based on simulating the behavior of a honeybee
colony when collecting nectar in nature. It was developed and proposed for use by D. Karaboga in
2005. Over the past nearly twenty years, numerous teams of scientists in various countries have
researched the behavior of bee colonies to address problems more effectively, using this algorithm.
The study of the interaction of bees with the environment and within the swarm suggested
approaches to finding optimal solutions Studying the interactions of bees with the environment and
within the hive has suggested approaches to finding optimal solutions in a large, complex and
multilevel society like ours. Scientists began to model “swarm intelligence” - attempts to make robotic,
automatic and automated swarms.</p>
      <p>A single bee is just an insect with a brain barely larger than a pinhead, a colony of bees is capable
of solving complex optimization problems through the coordinated actions of a large number of its
inhabitants. Bees successfully search for and find new sources of food and building materials for the
hive and accurately transmit information to their fellow bees, who, in turn, can quickly, "on the fly",
update their knowledge of the location of flowers and optimally rebuild flight routes over and over
again, saving time and energy.</p>
      <p>The bee colony algorithm includes initial exploration and subsequent work of the bees of the
hive. During initialization (initial exploration), exploration of the space features is performed to
determine, Kn, the most promising points with the best values of the objective function
f(X)=f(x1,x2,..., xnn), which are stored in the hive. After this, local reconnaissance is conducted near
the chosen points within a specified reconnaissance radius R to refine the solution and improve the
result. When an improvement is made, the updated value of the result (f) and the corresponding set
of parameters for the objective function (X) are saved in the hive. By combining the work of scout
bees and worker bees over a given number of iterations C, the algorithm ensures a gradual
improvement of the remembered sample R = [X1, X2,...,XK] from K solutions. Upon completion of its
work, the best solution is selected from the specified set of solutions, which is the result of the
algorithm [11], [13], [14], [15], [16], [17], [18], [19].</p>
      <p>A graphical representation of the ABC optimization algorithm in 2D is shown in Figure1.</p>
      <p>We fully agree with the position of the team of authors who conducted comparative analyses of
the modified ABC and other bio-inspired methods that “... the bee colony model is simple, has few
parameters and is very universal, which easily falls into the local optimum” [12]. In principle, the
properties of this approach (logical and quite understandable) focused our attention on its
applicability aspect in finding solutions to this type of research problem (Table 1).</p>
      <sec id="sec-3-1">
        <title>Problem</title>
      </sec>
      <sec id="sec-3-2">
        <title>1. Optimization of routes and resources:</title>
        <p>In an emergency or military conflict, rapid
delivery of medical supplies, equipment and
personnel is required, and this is under highly
changing conditions (destroyed infrastructure,
weather conditions, hazardous areas, changing
priorities).</p>
      </sec>
      <sec id="sec-3-3">
        <title>2. Scalability and adaptability</title>
        <p>Emergency medical logistics require high
flexibility and rapid adaptation to new
information and updated data (changing
weather, moving active combat operations or
increasing threats of new natural disasters).</p>
      </sec>
      <sec id="sec-3-4">
        <title>3. Decentralized management:</title>
      </sec>
      <sec id="sec-3-5">
        <title>ABC application</title>
        <p>The ABC algorithm can effectively find
optimal routes based on the identified key
factors and ways to distribute medical
resources by adjusting to them. This is
especially useful for planning routes for
medical teams, evacuating the wounded, or
delivering medicine in difficult conditions and
damaged infrastructure.</p>
        <p>The bee colony algorithm can easily adapt to
real-time changes in these and other
conditions. For example, if a medical supply
route becomes inaccessible due to a fire or
mass fire attack, ABC can quickly analyze
alternative delivery routes, minimizing delays
in assisting.</p>
        <p>In the absence of centralized control (for The bee swarm algorithm is based on
example, in areas with a destroyed decentralized problem solving, which allows
communication and communications system), each "agent unit" to independently make
decentralized adoption of operational operational management decisions based on
management decisions is required to the aggregated information received, including
successfully coordinate actions to deliver from "scout bees" - drones.
medical supplies.</p>
      </sec>
      <sec id="sec-3-6">
        <title>4. Inventory and resource management:</title>
        <p>In conditions of limited resources (blood for The ABC is applicable and can help optimize
transfusion, specific medications, equipment), the allocation of resources across emergency
and in some cases their absence, effective medical care centers based on current needs,
distribution and management of stocks is task priorities, and available resources.
required.</p>
      </sec>
      <sec id="sec-3-7">
        <title>5. Integration with drones and robotic systems:</title>
        <p>Modern logistics actively uses progressive The bee colony algorithm is successfully
technologies: unmanned technologies integrated with unmanned and robotic
(driverless cars, robotized equipment, various equipment to optimize the routes for the
types of drones) to deliver medicines, delivery of medical supplies, as well as to
especially to hard-to-reach places. coordinate autonomous equipment involved in
the evacuation</p>
      </sec>
      <sec id="sec-3-8">
        <title>6. Scenario analysis and strategic planning:</title>
        <p>In emergency medical logistics, it is necessary
to consider several alternative scenarios for
the situation development (from the rapid
movement of the front to the emergence of
new emergencies).</p>
        <p>The ABC algorithm allows the simulation of
various scenarios and planning strategies
depending on the availability of vehicles and
equipment, the request for a certain amount of
medical supplies and their actual availability,
and depending on the development of an
emergency.</p>
        <p>The use of artificial intelligence (AI) in the optimization modelling of emergency medical logistics
will significantly increase the efficiency of decision-making in conditions of uncertainty and
multitasking, which is extremely important for medical logistics in emergencies, such as
earthquakes, floods, fires, as well as in the localization of military conflicts. This approach will
occupy one of the key places in the "core" of the methodological model, since right AI allows
realization of the full potential of other methodological approaches, such as adaptability and
selforganization.</p>
        <p>The systems approach allows us to consider medical logistics as a complex dynamic system that
consists of many interconnected elements: the transport and logistics system, the medical care
system, medical resources, infrastructure support, management system, etc. This is important for
understanding how the various components of the system and incoming subsystems interact with
each other in an emergency.</p>
        <p>The integrated approach focuses on the whole problem, considering all its aspects and
multilevel interactions. In the case of applying ABC in emergency medical logistics, it is necessary to
consider not only the physical delivery of resources, but also factors such as the speed of response
to crisis events, the availability of communications, the state of the infrastructure, and the dynamics
of changing situations. An integrated approach will allow us to create models considering the crisis's
multifactorial and multi-level nature.</p>
        <p>The synergetic approach involves studying complex systems, specifically the effect of increasing
system efficiency through its component's integration and merging into a unified whole due to
emergence. Concerning medical logistics, especially during emergencies, it is vital to ensure that the
system's each element can independently execute its functions and interact effectively to achieve a
common goal. However, the effect of joint coordinated interaction will only be enhanced by
integration. The adaptive approach is focused on the ability of the system to quickly and effectively
change its structure and functional qualities in response to changes in internal and external
environmental factors. In conditions of military conflicts or natural disasters, the adaptability of the
logistics system is vital for providing medical care. This directly correlates with the essence of the
ABC algorithm, since it is adaptive in itself - it allows you to "rebuild" on the go, changing routes
and resource distribution in response to changes at a certain point in time, taking into account
several factors such as weather conditions, traffic conditions, infrastructure conditions, etc. Using
an adaptive approach in the study will allow us to model situations in which emergency medical
logistics must immediately respond to changes and offer optimal solutions. A bio-inspired ABC
algorithm, with integrated real-time monitoring systems (e.g., use drones and satellite systems), will
allow us to quickly respond to changing conditions and direct resources where they are most needed.</p>
        <p>The situational approach involves the analysis of specific conditions and circumstances in which
the system operates. In the context of medical logistics in emergency situations and military
conflicts, this approach emphasizes the uniqueness of each crisis situation. Each such situation
requires an individual approach, and it is important that the algorithms can effectively adapt to the
specific conditions of the situation, characteristic of a particular region, crisis, or availability of
specific resources. This will allow the ABC algorithm to best solve specific logistics problems.</p>
        <p>A cybernetic approach to control and modeling systems can be useful for analyzing feedback in
the medical logistics system, which is important for its adaptability and adjustment of actions based
on changes in the environment.</p>
        <p>Heuristic research methods allow finding optimal solutions to problems under conditions of
limited information and time. In the context of crisis medical logistics, this is extremely important,
since it is impossible to always have complete information about the situation.</p>
        <p>We also believe that it is appropriate that the inclusion of dynamic modeling and agent-based
modeling (ABM) in the methodological model will be useful and justified. These approaches will
provide a more in-depth analysis of complex interactions and help model the behavior of the system
in changing conditions. They thus expand and complement other approaches, offering more precise
and comprehensive solutions for optimizing medical logistics in emergency situations and post-war
remediation.</p>
        <p>In Figure 2, we present an integrative methodological design of a set of methods that will be
applicable together with the ABC optimization algorithm in the organization and management of
emergency medical logistics, namely: a set and organic integration of first-order scientific
methodological approaches (around the “core” - author's note) and the “periphery” - a set of
auxiliary, complementary and specific research methods.</p>
        <p>Based on a comprehensive analysis of scientific approaches that are most often used by
researchers in solving problems of emergency medical logistics management, we came to the
conclusion that it is advisable to identify a productive combination consisting of 7 scientific
approaches that form the core of the methodological model, the center of which is the bee colony
algorithm and 14 auxiliary scientific approaches that can be selected to solve specific problems.</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>3. Empirical model based on ABC and its integration References</title>
      <p>To develop an optimization algorithm for ABC taking into account the possibilities of integrating it
with advanced IT technologies, AI, IoT, and ML, we studied the proposals of other scientists who
studied real crises and the experience of emergency medical logistics in military activities, namely:
•
•
•</p>
      <p>COVID-19, the ABC algorithm was used in China for the dynamic distribution of medical
resources (medicines, equipment) in a crisis, which improved the speed and accuracy of
delivery of materials to the necessary medical institutions. This experience can serve as a
positive example of the application of ABC in medical logistics in any crisis [21];
The earthquakes in Turkey and Syria that occurred on February 6, 2023, killed more than
53,500 people in Turkey and from 5,951 to 8,476 people in Syria. The casualty toll is also
high, with more than 107,000 casualties reported in Turkey and around 14,500 injured in
Syria. The earthquake was one of the most devastating in the region's history, causing
widespread destruction in cities such as Gaziantep and Aleppo. We have thoroughly studied
the published research related to the analytical scientific analysis of this emergency event,
but they did not cover the issues of organizing logistics. At the same time, the authors' ideas
on using social networks (WhatsApp, Twitter) for transmitting data from victims to rescuers
at their location, and technological integration with hotline chatbots can be useful in solving
the issues we are studying and were taken into account. Special consideration should be
given to the documented and analyzed experiences presented in the article. This is crucial
when preparing for emergencies and handling real-time data from IoT devices, like drones.
Social networks can also improve emergency logistics coordination [22]. Furthermore, the
proposed scientists' concept regarding the rational distribution of food can be implemented
in the developed by us model [23].</p>
      <p>Additionally, the military actions in Ukraine, specifically the missile strike on the Okhmatdet
Children's Hospital in Kyiv on July 8, 2024, should be noted. More than 50 people were
injured, including seven children. The strike destroyed one hospital building and damaged
four others. The missile strike on Okhmatdet, the largest children's hospital in Ukraine, was
part of a larger attack in which Russian forces launched more than 40 missiles at cities in
Ukraine. The strike injured children undergoing treatment, including those undergoing
dialysis at the hospital. This attack caused international outrage and discussions about the
possibility of prosecution for war crimes. However, the authors of this article did not cover
this event in the framework of optimizing emergency logistics in cities, which also has its
specifics. In the next stage, the designed structure (presented in Figure 3) of the interaction
of key subjects managing the first medical aid and emergency logistics will be analyzed.</p>
      <p>We have identified the key entities involved in managing such emergencies to identify the
specifics of their interaction. The model we are developing includes:
1.
•</p>
      <p>Central Coordination Headquarters (CCH):
role: Managing all operations, planning, interacting with government and international
organizations;
•
2.
•
•
3.
•
•
interaction with other entities: receiving current data from all units (medical teams, logistics
departments) to make optimal management decisions on delivery priorities and resource
allocation.</p>
      <p>Medical Resources Logistics Unit (MRLU):
role: ensuring and monitoring the receipt and distribution of medical resources;
interaction with other entities: following direct instructions from the CCH and directly
interacting with medical teams to deliver medications and equipment to affected locations.
Rapid Response Medical Brigades (RRMB):
role: Providing emergency medical care and preparing for evacuation from emergency areas;
interacting with other entities: Transferring data to the Central Command Center about the
situation on the ground to coordinate further actions and deliver the necessary resources.</p>
      <p>Transportation and Logistics Department (TLD):
role: planning and coordinating all modes of transport (aircraft, land, water) for medical
resources delivery and evacuation of victims. Managing logistics warehouses and
warehousing to ensure continuous supply of necessary resources. Optimizing routes and
minimizing delivery times given the current situation. Monitoring the transportation safety
and the security of medical supplies in high-risk areas.
interacting with other entities: works closely with the Central Coordination Headquarters
(CCH) to gather data on priority medical resource delivery. Liaise with the Center for
Adaptive Resource Allocation and Routing (CARM), which adjusts delivery routes based on
real-time data considering the damage or blockages. Ensures prompt exchange of
information with the Communications and Information Center (CIC) to transmit timely data
on the availability of resources, the state of infrastructure support and route changes.
5. Communications and Information Division (CID):
• role: ensures communication between all participants;
• interaction with other entities: coordinates data collection, processing and transmission
between the military, civilian structures and international organizations involved in
emergency assistance.
6. Medical Evacuation and Hospitalization Centers (MEH):
• role: Assess the condition of victims and organize their movement;
• interaction with other entities: direct interaction with MEH to address the implementation
of emergency evacuation and placement of victims.
7. Analytical Forecasting and Preparation Division (AOPD):
• role: In-depth risk analysis and development of long-term strategies.
• interaction with other entities: transfers the results of analysis and assessment of alternative
scenarios to MEH for strategic planning and provision of resources.
8. Security and Protection Service (SPS):
• role: Ensuring personnel safety and medical resources safety.
• interaction with other entities: Interacts directly with the CCS and the Transport and
Logistics Department (including warehouse entities – author’s note) to ensure safety in all
areas of emergency medical care and logistics;
9. Center for Adaptive Resource Allocation and Routing (CARM):
• role: select optimal delivery routes and optimal resource provision in real-time with the use
of ABC.
• interaction with other entities: Processes data received from drones, satellites and response
teams, as well as first aid teams on the ground, interacts directly with the CCS to coordinate
the operational management process, primarily the most efficient provision of medical
resource delivery services to emergency locations.</p>
      <p>The next step in the development of the model will be visualization of the ABC algorithm in 3D
format (Figure 4).</p>
      <p>Based on the above, an integrated model for optimizing emergency medical logistics routes based
on ABC of a bee colony with the integration of IoT, ML and other IT technologies, including the
ability to take into account changes in weather conditions and destroyed infrastructure will look
like this:
ɷij (t) = ɷ0ij ∙ fwether (t)∙ fdestructions (t)∙ fIoT(t) ∙ (1+(Pml(t+ Δt))/K)
(1)
where:
ɷij (t) — is the current weight of the medical resource delivery route  → at time
ɷ0ij — is the initial weight of the delivery route (distance and travel time),
fwether (t) — is a coefficient that adjusts the overall route weight depending on changes in weather
conditions (e.g. worsening weather increases the route weight),</p>
      <p>fdestructions (t) —is a coefficient that takes into account changes in the state of point and linear
infrastructure (e.g. destruction of roads, hospitals, traffic jams),</p>
      <p>fIoT(t) — is a coefficient based on data transmitted from IoT sensors that make adjustments by
updating current data on changes in the situation (e.g. sensors record and transmit parameters of
weather conditions, current state of roads, traffic jams, etc.),</p>
      <p>Pml(t+ Δt) — a forecast calculated using ML allows predicting the state of routes after Δt time,
taking into account weather changes (improvement or deterioration) and infrastructure changes
(restoration or destruction/failure),</p>
      <p>K — is the normalization coefficient that determines the degree of influence on forecasts
generated by ML of a set of alternative routes for medical resources delivery.</p>
      <p>For a detailed content analysis of the presented integrated ABC model for optimizing routes for
emergency medical logistics, we present a description of its key elements:</p>
      <p>ɷ0ij — the base weight of the route, which reflects the initial conditions (e.g., normal delivery
time, the distance between points of the logistics route). This is a static value before the algorithm
starts to consider the impact of external factors.</p>
      <p>fwether (t) — a function of weather conditions that changes route weight depending on current and
forecasted weather changes. For example, if heavy rain or snowfall starts, the weight increases so
that the "bees" choose more optimal and safe delivery routes,</p>
      <p>fdestructions (t) — is a function that reflects the state of the infrastructure at a certain point in time.
If data transmitted from drones or sensors reports the destruction of railway tracks or a bridge, the
route weight increases sharply or becomes infinite, which makes the route unsuitable for choosing
emergency delivery of medical supplies,</p>
      <p>fIoT(t) — is a coefficient depending on the data collected from the IoT- sensors at a given point in
time. These sensors can provide information about traffic, road conditions or other specific obstacles
that influence the choice of the optimal delivery route,</p>
      <p>Pml(t+ Δt) — is the forecast calculated by ML about the availability of the restored delivery route
after a certain time. This can be useful for predicting how the availability of alternative routes for
medical resource logistics will change in the future (for example, if active restoration work is
underway on railway lines or weather conditions are predicted to improve).</p>
      <p>K — is a normalizing coefficient that determines how much the ML forecasts will influence route
selection compared to current conditions.</p>
      <p>This formula combines the model's all the components, allowing the bee colony algorithm to
dynamically adapt to the changes in infrastructure, and weather conditions and use modern IT
technologies to make optimal decisions in emergency medical logistics.</p>
      <p>The main stages of the proposed ABC model:</p>
      <p>Data collection from IoT and drones: sensor systems collect information about the state of
the infrastructure and weather conditions; drones and sensors transmit data on destruction
and other obstacles.</p>
      <p>Real-time data processing: ML analyzes the collected data and makes forecasts about the
future state of delivery routes (e.g. restoration of a highway or worsening weather
conditions).</p>
      <p>Decision making by the integrated ABC algorithm: "scout bees" explore possible routes for
the delivery of resources, "forager bees" perform the assigned real logistics tasks, and</p>
      <p>"observer bees" analyze all possible delivery routes and choose the most effective routes
based on the collected data.</p>
      <p>Optimization of emergency logistics routes in real time based on changing conditions:
continuous data update and formation of optimal logistics routes in real-time; the system
allows dynamic adaptation to changes in infrastructure and weather conditions, thus
changing the route weight based on the information received.</p>
      <p>Reporting and adjustments: ML models adjust routes by learning from new data received to
optimize the system’s operation in the future.</p>
      <sec id="sec-4-1">
        <title>Implementation example:</title>
        <p>If, for example, the road  → was accessible (low weight), but was hit by heavy snowfall and a
drone reported the destruction of a part of the road, the coefficients  weather( ) and  destruction( ) will
sharply increase the route weight, which will force the “scout bees” to look for alternative routes
for emergency delivery of medical supplies.</p>
        <p>At the same time, the ML model can predict that the road will be cleared in 6 hours, which will
be reflected in the coefficient  ml( +Δ ) and the system will allow choosing this route for future use
when weather conditions improve.</p>
        <p>The practical application of the integrated model for optimizing emergency medical logistics
routes based on the Bee Colony (ABC) algorithm, using IoT technologies, machine learning (ML)
and other IT technologies, is critical for effective management in emergencies. This model allows
for the dynamic adaptation of routes in real time, taking into account possible changes in weather
conditions and the destruction of linear and point infrastructure, which is especially important for
disasters such as earthquakes, fires or military conflicts.</p>
        <p>Detailed significance of using the integrated ABC optimization model:
1. Operational adaptation of routes. ABC-based control systems can instantly respond to changes
in critical situations, transmitted via IoT sensors or drone data, allowing for updates and optimal
routes for the delivery of medical resources. This is especially important in the context of natural
disasters, such as the earthquakes in Turkey and Syria, where the destruction of infrastructure
requires constant monitoring and adjustment of logistics.</p>
        <p>Forecasting and predictive analytics. Using ML machine learning allows for the most accurate
forecasting of future changes, such as the restoration of roads for the delivery of goods and medical
personnel, as well as worsening weather conditions. This allows for pre-adjustment of routes taking
this into account, which increases the efficiency of emergency medical logistics and reduces delays
in assisting in disaster areas, as was the case with the massive fires in Australia and the USA.</p>
        <p>3. Saving lives in wartime. In military operations, such as those currently taking place in Ukraine,
the use of ABC and IT technologies helps to optimize routes for the evacuation of victims and the
delivery of vital medical resources. Timely delivery of medical care in the shortest possible time can
minimize civilian casualties and increase the resilience of medical logistics in the face of destruction
of various types and scales. In the context of military activity, after the end of its active phase, the
use of the integrated ABC model presented in the article will effectively solve a set of problems of
medical care for the affected population as part of remediation. In conclusion, we have aggregated
and presented a generalized description of the necessary software and hardware for the
implementation of an integrated model for optimizing emergency medical logistics routes based on
the Bee Colony (ABC) algorithm with the integration of IoT, machine learning (ML) and other IT
technologies (Table 2).
IdoaTt-aHAuWbSforIopTroCceosrseinogr sAenzusorer dev-icDersones and mobile sensor</p>
        <p>- TensorFlow, PyTorch for - Graphics processing units
creating and training (GPUs) for accelerated data
forecasting models processing</p>
        <p>scikit-learn for simple - Big data storage and
machine learning models processing systems
Fplrion-ckeAsspianfcgohre Kasftkraeaomr Apadcahtea ana-lySseirsvers for real-time data
ana-lyMticAsTaLnAdBvisouralRizaftoiorndata - Network data storage</p>
        <p>- ArcGIS, QGIS for working
with cartographic data</p>
        <p>- Satellite images and GIS
services</p>
      </sec>
      <sec id="sec-4-2">
        <title>Google Maps</title>
        <p>Dynamic Routing
API for
- GPS trackers on vehicles
- OpenWeatherMap API for
getting weather data
- Video surveillance with
drones</p>
      </sec>
      <sec id="sec-4-3">
        <title>NASA FIRMS for Fire - Automated weather</title>
        <p>Monitoring stations</p>
        <p>- Twilio API, Slack API for - Mobile and satellite
communication between phones for emergency
departments communications</p>
        <p>- AWS Shield or Cloudflare - Secure cloud data storage
for protection against DDoS
attacks</p>
        <p>- Tableau or Power BI for
data visualization</p>
        <p>- AnyLogic for modeling
agent-based systems</p>
        <p>- MATLAB Simulink for
simulating logistics processes
- Monitoring displays and
workstations</p>
        <p>- Specialized vehicles with
sensors and trackers</p>
        <p>- Transport hubs and
warehouses for storing
resources</p>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>4. Discussion and Future Directions</title>
      <p>This study presented an integrated route optimization model for emergency medical logistics based
on the ABC using IoT, machine learning, and other IT technologies. Further discussion is needed on
how effectively the model adapts to dynamic changes in infrastructure and weather conditions,
which is especially important in the context of natural disasters and military conflicts. In the future,
we plan to focus on deeper integration of this model with blockchain technology to ensure the
security and transparency of data transfer. This will improve coordination between various entities
involved in emergency medical care management and strengthen the resilience of medical logistics
in conditions of high uncertainty and risk.</p>
    </sec>
    <sec id="sec-6">
      <title>5. Conclusions</title>
      <p>An integrated model for optimizing emergency medical logistics routes based on the ABC algorithm
using IoT, machine learning (ML) and other IT technologies allows for dynamic adaptation of
medical resource delivery and casualty evacuation routes in real-time, considering weather
conditions changes and infrastructure destruction. This significantly improves the efficiency and
safety of logistics, especially in natural disasters such as earthquakes in Turkey and Syria, fires in
Australia and the United States, and military conflicts in Ukraine. Such a system can significantly
reduce the number of casualties by providing timely medical care in critical situations.</p>
    </sec>
    <sec id="sec-7">
      <title>6. Declaration on Generative AI</title>
      <p>During the preparation of this work, the authors used ChatGPT to: partially translate the original
text from Ukrainian into English and check grammar and spelling. After using this tool, the authors
reviewed and edited the content as needed and take full responsibility for the content of the
publication.</p>
    </sec>
    <sec id="sec-8">
      <title>7. Acknowledgements References</title>
      <p>We thank the anonymous reviewers, scientific editors, and editors for their valuable comments and
recommendations.
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</article>