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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Secure information system for Chinese Image medicine knowledge consolidation</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Serhii Lupenko</string-name>
          <email>lupenko.san@gmail.com</email>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Oleksandra Orobchuk</string-name>
          <email>orobchuko@gmail.com</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Ihor Kateryniuk</string-name>
          <email>igor.kateryniuk@gmail.com</email>
          <xref ref-type="aff" rid="aff3">3</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Ruslan Kozak</string-name>
          <email>ruslan.o.kozak@gmail.com</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Halyna Lypak</string-name>
          <email>halyna.lypak@gmail.com</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Department of Computer Science, Ternopil Ivan Pului National Technical University</institution>
          ,
          <addr-line>Ternopil</addr-line>
          ,
          <country country="UA">Ukraine</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Department of Cybersecurity Ternopil Ivan Pului National Technical University</institution>
          ,
          <addr-line>Ternopil</addr-line>
          ,
          <country country="UA">Ukraine</country>
        </aff>
        <aff id="aff2">
          <label>2</label>
          <institution>Institute of Telecommunications and Global Information Space, National Academy of Sciences of Ukraine</institution>
          ,
          <addr-line>02000 Kyiv</addr-line>
          ,
          <country country="UA">Ukraine;</country>
          <institution>Department of Computer Science, Opole University of Technology</institution>
          ,
          <addr-line>Opole</addr-line>
          ,
          <country country="PL">Poland</country>
        </aff>
        <aff id="aff3">
          <label>3</label>
          <institution>Python teacher, Beetroot Academy</institution>
          ,
          <addr-line>Kyiv</addr-line>
          ,
          <country country="UA">Ukraine</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>the work is devoted to the topical issue of building an information system for consolidating knowledge of Chinese image medicine, which would contain comprehensive and objective information of this health-improving direction of folk and complementary medicine. The verbal and descriptive modeling of the consolidated resource was carried out, its functional diagram was built, and the actors and their roles in this resource were graphically visualized. The security threats and respective mitigations have been identified to enhance the information system modeling phaze.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;data consolidation</kwd>
        <kwd>Chinese traditional medicine</kwd>
        <kwd>consolidated information resource</kwd>
        <kwd>secure information system 1</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Currently, there is an active integration of conventional (Western, traditional) medicine and
alternative (folk, complementary) medicine in the world, as conventional (Western) medicine is
becoming increasingly dependent on technological solutions that are expensive and not always
effective or have side effects. Instead, integrative medicine supports holism and many simple
methods of prevention and treatment, which are the basis of traditional medicine and are
gaining popularity among patients. Medical tourism is also actively developing in order to find
alternative and complementary medical care; there are attempts to use the latest computer
technologies and artificial intelligence [
        <xref ref-type="bibr" rid="ref1 ref2 ref3">1-3</xref>
        ]. In 2022, the size of the global complementary and
alternative medicine market was estimated at USD 117,210.3 million, and it is expected to grow
      </p>
      <p>0000-0002-6559-0721 (S. Lupenko); 0000-0002-8340-913X (O. Orobchuk); 0000-0002-9542-6279 (I. Kateryniuk);
0000-0003-1323-6448 (R. Kozak); 0000-0001-9187-5758 (H. Lypak)</p>
      <p>
        © 2023 Copyright for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).
by 25.1% per year on average from 2023 to 2030 [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. Therefore, the involvement of alternative
medicine, and in particular, Chinese image medicine (CIM), in integrative medicine will expand
and strengthen its capabilities, increase the income of integrative medicine centers, thus
improving the economy of the countries where they are located.
      </p>
      <p>
        For the further development of integrative medicine, it is necessary to ensure access to the
specific knowledge of traditional medicine, the possibility of its research and scientific
interpretation, since most of this knowledge is empirical or in sources accessible to a limited
number of people. This is the state of affairs in alternative and complementary medicine, which
has several thousand years of experience in prevention and healing and is gaining interest
around the world. This task is in line with the WHO strategy [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ] and the international research
program of CIM [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ], and its solution will be facilitated by the creation of a consolidated
information resource for the subject area of Chinese Image Medicine.
      </p>
      <p>Modeling an information system for the consolidation of CIM knowledge as a means of
preserving the unique knowledge and empirical experience of Chinese image therapists is an
urgent and important task for the further popularization and effective functioning of CIM, as
well as its digitalization. The full-functional practical implementation of such a consolidated
system is a complex technological and organizational task, so at the initial stage we will focus on
verbal and descriptive modeling, which will be supplemented by a functional diagram and
graphical visualization of the main actors of the system and their roles. Attention will also be
paid to the security issues of the future web application, in particular, current threats will be
highlighted and countermeasures will be suggested.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Related Works</title>
      <p>
        Despite the fact that the protection of patients' personal data is of paramount importance in the
healthcare sector, there are almost no protected consolidated resources for non-traditional types
of healthcare. Many researchers have dealt with the use of protected consolidated resources (N.
Borysova, G. Kalytych, M. Bondarenko, M. Middleton, S. Land, B.Greene, R. Rouse,
J.Castagnetto, R. Niedner, D. Sawadogo, R. Champagnat, P. Estraillier, C. McCord and others).
However, they focused only on general approaches or certain aspects of their practical
implementation [
        <xref ref-type="bibr" rid="ref7">7-10</xref>
        ], while an integrated approach is important for the development of an
information system for consolidating CIM data with secure resources (which will ensure
integrity, confidentiality, availability, authenticity).
      </p>
      <p>In this study, we will follow the approach outlined in [11]. In the author's interpretation, the
process of data consolidation consists in the systematic integration of various types of
information resources obtained from many sources, which has the properties of integrity,
consistency, completeness and which forms an adequate information model of the subject area.
It is this approach that will allow for high-quality analysis, logical and semantic processing, and
effective use of this information both in the study of the conceptual apparatus, methods and
means of treatment and diagnosis of CIM, and in its development as a scientific component of
integrative medicine.</p>
      <p>The first steps in this direction have already been taken: for example, the authors analyzed
the methods of extracting and electronically recording the diagnostic and therapeutic
experience of image therapists; in [12], a computer ontology of CIM based on an
axiomaticdeductive strategy for organizing CIM knowledge to solve the problem of their semantic
heterogeneity was developed. However, the absence of a unified knowledge base significantly
complicates the accumulation, systematization, qualitative analysis of diagnostic and
therapeutic information, and, accordingly, in-depth research and construction of a scientific
theory of this medical practice. The information system of knowledge consolidation for the
subject area of CIM should play the role of a kind of repository containing pre-found, filtered by
the criteria and processed information [13], which fully and relevantly reflects the theoretical
and practical knowledge of CIM.</p>
      <p>Such consolidated information should be presented in a form convenient for the user, at a
time determined by him/her, regardless of his/her location, and provide him/her with a holistic
picture of the problematic issue with the ability to track its development in dynamics, some
immediate solutions to problems and information needs of a particular clientele or social group
that may not be able to effectively access and use this knowledge as available in several
documents or in another form [14].</p>
      <p>It should be noted that it is difficult to consolidate knowledge of Chinese image medicine for
a number of objective reasons:




territorial dispersion of knowledge;
different forms of knowledge storage (a small share in paper form and the lion's share
empirical knowledge of image therapists);
lack of formalization, heterogeneity, and contradictory knowledge;
lack of unification of diagnostic and treatment methods.</p>
      <p>Without a single resource, these problems will only get worse, because as the number of
image therapists in the world increases, each of them will interpret their cognitive experience in
their own way. This will increase contradictions, inconsistencies, and subjectivity in this
already difficult to understand and scientifically comprehend area of traditional medicine, and
thus will be an obstacle to the formation of the scientific direction of CIM and its integration into
integrative medicine.</p>
    </sec>
    <sec id="sec-3">
      <title>3. Proposed methodology</title>
      <p>We believe that the most convenient physical embodiment of the CIM knowledge consolidation
system is a web portal that will integrate the found and filtered data from the CIM field and
provide a convenient search by specified criteria for this data, followed by the formation of an
information product in response to a user's request.</p>
      <p>The main components of the consolidated information resource of any industry are a
database of information sources of a given subject area and an automated information retrieval
system as a means of interaction with it. It is proposed to use the developed CIM ontology [15],
as well as digitized materials (articles, research results, descriptions of practical cases of image
therapists, etc.) The concept of "consolidated information" covers information resources
obtained from several sources and systematically integrated of various types, and the ontology
allows them to provide the properties of completeness, integrity, consistency and to create an
adequate information model of the problem area for the purpose of its analysis, processing and
effective use in decision support processes.</p>
      <p>In our study, data consolidation also means the collection of data from geographically
distributed or multi-platform data sources into a single data warehouse for the purpose of
further processing, analysis, and use in an ontology. It should be borne in mind that this data is
often unstructured (it can be data from various documents, reports and web pages), which is
inherent in CIM. At the same time, it is possible to restructure and organize this knowledge
based on the recommendations and consultations of future users - practicing.</p>
      <p>As for remote resources outside the database, they should be presented in digital format
and/or equipped with detailed descriptions – metadata created according to the relevant
standards. The metadata exchange system will ensure that the database of the CIM knowledge
consolidation information system is constantly updated, through which end users will be able to
access the necessary information resources through advanced search. Taking into account the
specificity of the CIM knowledge data, its empirical nature and the dispersion of the available
recorded data, it is necessary to agree on the format of presentation of metadata of these
information resources.</p>
      <p>Tasks to be solved by the information system of knowledge consolidation of the CIM are the
following tasks:





comprehensive satisfaction of information needs of a wide range of users regardless of
their location;
consolidation, structuring, preservation of large volumes of CIM-information reflecting
not only in-depth historical knowledge of the industry, but also the current state of
scientific research (scientific articles, conference materials, experimental results, etc);
criterion-based search for CIM information (e.g., by symptoms, methods of exposure to
the body, etc;)
ensuring effective exchange of CIM information both between image therapists and
interested users (patients, doctors representing other medical fields);
ensuring the protection of patients' personal data (in terms of diagnosis) and copyright
(in terms of research and experimentation results).</p>
      <p>The primary tasks of the preparatory stage in the development of an information system for
the consolidation of Chinese traditional medicine knowledge are to establish the process of
extracting knowledge from experts and formalizing it; it is also important to unify and
internationalize the CIM terminology.</p>
      <p>Given the specificity of CIM knowledge data, its empirical nature, and the scattered nature
of the available recorded data, it is necessary to harmonize the format for presenting metadata of
these information resources.</p>
    </sec>
    <sec id="sec-4">
      <title>4. Results</title>
      <sec id="sec-4-1">
        <title>4.1. Modeling of the information system of knowledge consolidation of the CIM</title>
        <p>We will build a functional diagram of the information system for consolidating knowledge of
Chinese image medicine using the IDEF0 methodology [16] (Fig. 1).</p>
        <p>Block A1 "Consolidation of information in the knowledge base" receives information from
various sources. From the Image Therapist subsystem comes diagnostic and therapeutic data
that is already ontologically "formatted".</p>
        <p>Articles by image therapists, scientific articles, and other documents go through the process
of adding tags (block A0) before they are included in the knowledge base [17, 18]. The tags are
immediately applied by the automatic tagging module (based on AI), and the expert group later
checks and corrects the tags if necessary.</p>
        <p>Module A2 provides the user with the resulting information, which depends on the user's
role and request. Thus, unauthorized users will be able to view publicly available materials,
authorized users will have access to their diagnostic and therapeutic information, image
therapists will have access to information about their patients, experimental results, etc.</p>
        <p>In order to ensure the efficient use and maintenance of the CIM knowledge consolidation
system, it is necessary to identify the main actors and define their roles in the system. Let's show
this in a use-case diagram (Fig. 2). The first actor is the "Authorized User", which can be an
image therapist who has advanced capabilities of using the resource (for example, adding
materials) and an ordinary user who is only granted the right to view information without
modifying it. Given the specifics of the subject area, it is advisable to use an authentication
system with sets of rights and privileges for each type of actor.</p>
        <p>The "Administrator" actor performs most of the functions in the system: it works with
content (adding, editing, deleting), with users (granting and editing access rights, changing
status), with interface settings, performs SEO optimization, and provides the necessary security
parameters. It is granted a set of rights that includes the sets of rights of lower-level actors
(image therapist and end-user). A more limited set of rights is granted to the Image-therapist
actor (these users have the right to enter diagnostic and therapeutic information), and an even
more limited set of rights to the end-user actor (who has the opportunity to expand it by
becoming an image-therapist and receiving confirmation of the status upgrade from the
administrator).</p>
      </sec>
      <sec id="sec-4-2">
        <title>4.2. Designing the secure information system of knowledge consolidation of the CIM</title>
        <p>As a web-application in cloud environments, the information system's security layer for CIM
needs to be correctly established and meticulously planned. A variety of information security
and cybersecurity risks must be addressed in order to protect the information system for CIM as
a whole and each component in particular. Since the knowledge database's processed and
collected data is a valuable asset, appropriate security measures must be developed and
implemented.</p>
        <p>Because the information system for CIM works with personal health data, best security
practices consistent with industry standards and laws must be applied by default. One of the
most important stages of system modeling, security by design, means that security requirements
must be determined so that engineers can create a workable and secure system. Threat modeling
serves as a valuable approach to determine security requirements. By utilizing this method,
security needs can be identified, threats and vulnerabilities can be discovered, and their impact
and severity can be assessed. This enables the prioritization of effective solutions and measures.
The application of this method extends to various areas such as software, networks, databases,
and APIs.</p>
        <p>In the context of the information system for CIM and user personal data, the STRIDE [19, 20]
threat modeling methodology has been employed to identify and characterize inherent threats
and vulnerabilities. To further analyze the architecture depicted in Figure 2, a general data flow
diagram and threat model, as shown in Figure 3, have been developed. The applications and
technologies discussed in paper [21] are examined within this framework. For the purpose of
this research, all components of the diagram have been thoroughly analyzed to address potential
attack surfaces that the information system devices may encounter. The study investigates
whether there are any threats and risks to the system components and the data processed within
the system, considering its availability via the Internet.</p>
        <p>Table 1 provides a comprehensive overview of the threats and countermeasures associated
with the information system for CIM. This valuable resource assists software engineers and
security experts in designing and enhancing the system's security.</p>
        <sec id="sec-4-2-1">
          <title>Component</title>
          <p>Knowledge
Data Base</p>
        </sec>
        <sec id="sec-4-2-2">
          <title>Threat</title>
          <p>A malicious actor can take advantage of
inappropriate access management
which can lead to the data
confidentiality and integrity got
compromised</p>
        </sec>
        <sec id="sec-4-2-3">
          <title>Countermeasure</title>
          <p>Apply appropriate access
controls (e.g. RBAC),
Encrypt sensitive data at rest,
Keep software components
updated
Information
System for</p>
          <p>CIM
Administrator
Administrator</p>
          <p>Request /
Response for
Administrator</p>
          <p>Authorized</p>
          <p>User
User Request /
Response for</p>
          <p>User
E-learning</p>
          <p>System</p>
          <p>An attacker can exploit the
vulnerabilities of program system
components, resulting in an attacker’s
escalation of privileges or system
getting unavailable to authorized user
An attacker might attempt to takeover
the administrator credentials and access
the system, resulting in an attacker will
access the system’s data and
configurations
A malicious actor can intercept traffic
sent between the administrator and the
information system, which might result
in a malicious actor will be able to
modify or read the data</p>
          <p>Perform security tests and
vulnerability scanning to
identify and fix vulnerabilities,
Apply principles of least
privilege,
Regularly monitor and analyze
the performance and
availability of the system,
Implement protection DDoS
attacks
Implement two-factor
authentication (2FA),
Use secure browsers and strong
passwords,
User awareness and vigilance
against phishing
Validate and sanitize user input
to prevent injection attacks,
Implement data integrity
mechanisms,</p>
          <p>Encrypt sensitive data in transit
An attacker might attempt to capture Implement two-factor
the authorized user credentials and authentication (2FA)
access the system, resulting in an Use secure browsers and strong
attacker will access or change the users’ passwords
information User awareness and vigilance</p>
          <p>against phishing
A threat actor can try to modify or read
the data sent between the authorized
user and the information system, which
might lead to the user request and
response data will be modified and/or
compromised
A poisionous person may install the
malicious server and impersonate the
elearning system, resulting in the
information system will receive
incorrect data</p>
          <p>Validate and sanitize user input
to prevent injection attacks,
Implement data integrity
mechanisms,
Encrypt sensitive data in transit
Use strong authentication
mechanism,
Use antivirus and firewall
protection,
Use signature and timestamping
techniques in the audit records</p>
          <p>E-learning
Data In / Out
Expert System
of CIM</p>
          <p>Expert
Request /
Response
System of
Research in</p>
          <p>CIM
Research
Request /
Response</p>
          <p>A malicious actor can intercept traffic
sent between the e-learning system and
the information system, which might
result in a malicious actor will be able
to modify or read the input/output data
An attacker can deploy the malicious
server and impersonate the expert
system of CIM, resulting in the
information system will receive
malicious data or code
A threat actor can try to change or
capture the data sent between the
expert system for CIM and the
information system, which might lead
to the expert request and response data
will be modified and/or compromised
A malicious actor can install the nasty
server and impersonate the system of
research in CIM, leading to the
information system will receive
malicious data or software
An attacker may eavesdrop the
communication between the system of
research in CIM and the information
system, which might result in a
malicious actor will be able to modify
or read the research request and
response data</p>
          <p>Secure communication
protocols,
Implement protection
mechanisms against DDoS
attacks,
Implement data integrity
mechanisms
Use strong authentication
mechanism,
Use antivirus and firewall
protection,
Use signature and timestamping
techniques in the audit records
Secure communication
protocols,
Implement protection
mechanisms against DDoS
attacks,
Implement data integrity
mechanisms
Use strong authentication
mechanism,
Use antivirus and firewall
protection,
Use signature and timestamping
techniques in the audit records
Secure communication
protocols,
Implement protection
mechanisms against DDoS
attacks,
Implement data integrity
mechanisms</p>
          <p>By adopting this approach, the modeling of the information system ensures the protection of
sensitive data and privacy-related information from the growing risk of cyber-attacks targeting
IoT-enabled industrial systems. Moreover, it offers traceability in cyber security and privacy
audits, enabling organizations to showcase their compliance with applicable regulations.</p>
        </sec>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>5. Conclusions and prospects for further research</title>
      <p>The modeled information resource will define the real semantics of the CIM sphere, which will
allow to present computerized data in a form convenient for human perception; will ensure
integration of data and knowledge and their reuse, in particular, will help in the development of
more multifunctional and interoperable information systems in the field of CIM. Role
distribution of user functions by with the help of a precedent diagram will allow to clearly
formulate requirements for to the practical implementation of the CIM web resource.</p>
      <p>A proposal has been put forward for the development of a secure-by-design information
system. In order to tackle potential vulnerabilities, an analysis of the system components has
been conducted through threat modeling, with a focus on identifying and addressing any
extended attack surfaces that the system may face. Protecting this web application from attacks
is especially important because it processes patient medical data, and this will help prevent
leakage of confidential information and unauthorized access. Robust cyber security measures
ensure the safety of sensitive data while maintaining patient trust and compliance with
regulatory requirements.</p>
      <p>A promising direction for further development of such a consolidated resource is its
intellectualization with elements of machine learning (the ability to establish a preliminary
diagnosis of patients based on the entered symptoms and obtaining advice on treatment with
the use of CIM methods), which will be implemented in the expert system of CIM, which is a
part of the integrated ontology environment CIM.
[8] O. Kymytsia, "Formation of consolidated information resources of architectural
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