Preface The interest in integrating Ontologies and Software Engineering has gained more at- tention with commercial and scientific initiatives. The Semantic Web Best Practice and Deployment Working Group (SWBPD) in W3C included a Software Engineer- ing Task Force (SETF) to explore how Semantic Web and Software Engineering can cooperate. The Object Management Group (OMG) has an Ontology Platform Spe- cial Interest Group (PSIG) aiming at formalizing semantics in software by knowl- edge representation and related technologies. In counterpart, as Model Driven Engineering spreads, disciplines like model transformation and domain specific modeling become essential in order to support different kinds of models in an model driven environment. Understanding the role of ontology technologies like knowledge representation, automated reasoning, dy- namic classification and consistence checking in these fields is crucial to leverage the development of such disciplines. The TWOMDE 2008, affiliated with the 11th International Conference on Model Driven Engineering Languages and Systems (MoDELS2008), brought together re- searchers and practitioners from the modeling community with experience or inter- est in MDE and in Knowledge Representation to discuss about: (1) how the scientific and technical results around ontologies, ontology languages and their correspond- ing reasoning technologies can be used fruitfully in MDE; (2) the role of ontologies in supporting model transformation; (3) and how ontologies can improve designing domain specific languages. The objective of the workshop was: (1) to present success cases of integrated ap- proaches; (2) to present state-of-the-art researches covering ontologies in MDE; (3) and to encourage the modeling community to explore different aspects of ontolo- gies. Toulouse, Fernando Silva Parreiras, Jeff Z. Pan September 2008 Uwe Assmann, Jakob Henriksson v