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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Using Process Mining to Connect Process Orientation and Data-driven Decision Making in Healthcare: a Qualitative Assessment and Integration of New Data Sources</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Maxim Riebus</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>UHasselt - Hasselt University, Digital Future Lab, Agoralaan</institution>
          ,
          <addr-line>3590 Diepenbeek</addr-line>
          ,
          <country country="BE">Belgium</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>UHasselt - Hasselt University, Faculty of Business Economics</institution>
          ,
          <addr-line>Agoralaan, 3590 Diepenbeek</addr-line>
          ,
          <country country="BE">Belgium</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>Healthcare organizations face increasing pressure to deliver care that is not only eficient and cost-efective, but also patient-centered and responsive. In this context, process orientation (PO) and data-driven decision making (DDDM) are widely promoted as complementary paradigms to improve healthcare delivery. However, their integration in daily practice remains fragmented. While PO fosters end-to-end thinking across organizational silos, DDDM relies on the growing availability of healthcare data to support operational and clinical decisions. The central aim of this doctoral research is to strengthen the connection between PO and DDDM by enriching process insights with experiential and engagement-related dimensions of care. Process mining bridges both approaches by analyzing real-world care pathways. Yet, most applications only focus on execution data, which limits the scope of how the patient experienced the process. This doctoral research explores how non-traditional data sources, specifically remote health monitoring and patient-reported experience data can be integrated into process mining analyses. In doing so, the research identifies key methodological, technical, and organizational challenges that arise when extending process mining beyond its conventional data foundations. The research is structured around three interrelated studies: (1) a qualitative study of Flemish hospital departments to assess the current state, opportunities and challenges of integrating PO and DDDM; (2) a process mining study using remote monitoring data in a cardiology context; and (3) a process mining study at a hospital that combines event logs with patient experience data in a breast cancer care pathway. Together, these studies aim to advance both the conceptual understanding of process mining as a means to integrate PO and DDDM, and its methodological application in data-rich, patient-centered healthcare environments.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;Process Mining</kwd>
        <kwd>Process Orientation</kwd>
        <kwd>Data-driven Decision Making</kwd>
        <kwd>Healthcare</kwd>
        <kwd>Remote Monitoring</kwd>
        <kwd>Patient Experience</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Healthcare organizations are under growing pressure to provide care that is not only eficient and
costefective, but also tailored to the needs and expectations of patients. To address this, process orientation
(PO) and data-driven decision making (DDDM) are increasingly promoted as complementary approaches
to enhance healthcare delivery. Yet, their integration into daily practice remains limited and fragmented
[
        <xref ref-type="bibr" rid="ref1 ref2">1, 2</xref>
        ].
      </p>
      <p>
        In healthcare, PO is all about creating patient-centered care pathways that go beyond the usual
boundaries between departments. By organizing healthcare activities into clear and eficient processes,
hospitals can boost both the quality and eficiency of the care they provide. Research has shown
how powerful this approach can be, especially when it comes to improving teamwork across diferent
functional or clinical areas and making sure healthcare services are actually meeting patient needs
[
        <xref ref-type="bibr" rid="ref3 ref4">3, 4</xref>
        ]. At the same time, the growing availability of healthcare data and the rise of advanced analytics
are fundamentally transforming healthcare practice. With access to detailed data from sources such
as electronic health records and real-time monitoring systems, healthcare providers are increasingly
able to make timely and evidence-based decisions. By systematically analyzing operational and clinical
data, organizations can optimize decision-making processes, enhance workflow eficiency, and build
a more adaptable and sustainable healthcare system [
        <xref ref-type="bibr" rid="ref5 ref6">5, 6</xref>
        ]. Process mining serves as a crucial bridge
between PO and DDDM in healthcare. By extracting insights from event logs, process mining enables
organizations to analyze and improve workflows based on process execution data [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ]. This approach
ofers a unique way to uncover ineficiencies, visualize patient pathways, and align workflows with
clinical guidelines [
        <xref ref-type="bibr" rid="ref10 ref11 ref8 ref9">8, 9, 10, 11</xref>
        ].
      </p>
      <p>
        As healthcare and the societal context in which it is positioned is always evolving, it is crucial
to keep improving processes and data strategies to match changes in clinical practices and patient
needs [
        <xref ref-type="bibr" rid="ref1 ref12">1, 12</xref>
        ]. Two notable developments in this regard are the rise of remote health monitoring and the
growing emphasis on patient experience as a quality indicator [
        <xref ref-type="bibr" rid="ref13">13, 14, 15</xref>
        ]. These evolutions bring new
types of data into the healthcare setting, including patient-generated data from wearable devices and
survey-based insights into patients’ perceptions of care. While these sources capture valuable behavioral
and experiential aspects of care [16, 17, 18], they are still rarely leveraged in process mining research
and applications. As a result, their potential to enrich process analysis and optimization remains largely
unexplored.
      </p>
      <p>This doctoral research explores how non-traditional data sources, specifically remote health
monitoring and patient experience data can be integrated into process mining. It also investigates the
methodological and technical challenges that arise when adding these non-traditional data types to
process mining projects. To better understand how PO and DDDM are currently applied in practice,
the research includes three interrelated studies: (1) a qualitative study of Flemish hospital departments
to assess the current state, opportunities and challenges of integrating PO and DDDM; (2) a process
mining study using remote monitoring data; and (3) a process mining study at a hospital that combines
event logs with patient experience data. The relationship between these projects is presented in Figure 1.
Together, these studies aim to deliver both conceptual and practical contributions to the inclusion of
new data sources in process mining projects for the healthcare domain.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Related Work</title>
      <p>
        Process mining has gained significant traction in healthcare research as a technique for enabling
datadriven process analysis. Numerous studies and review papers have illustrated a variety of use cases,
including patient flow mapping, treatment variation analysis, and bottleneck identification in care
delivery [
        <xref ref-type="bibr" rid="ref11 ref12">19, 11, 20, 12</xref>
        ]. Other studies have demonstrated the feasibility and value of applying process
mining in healthcare contexts. De Roock et al. [20] reviewed 263 papers and confirmed the growing
maturity of the field, with a broad range of applications across clinical and administrative domains. Mans
et al. [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ] conducted one of the earliest case studies by analyzing gynecological oncology care pathways
in a Dutch hospital using real event log data. Their work showed how process mining techniques
can uncover deviations and variations in clinical pathways. More recently, Agostinelli et al. [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ] used
process mining to support governance in hospital settings. Their case study demonstrated how clinical
processes can be reconstructed and monitored to assess compliance and identify ineficiencies, thereby
providing actionable feedback to management.
      </p>
      <p>
        These studies confirm that process mining can generate added value in healthcare by reconstructing
real-world processes to identify areas of improvement using the event data captured and derived from
the HIS [
        <xref ref-type="bibr" rid="ref8 ref9">8, 9</xref>
        ]. However, HIS data often focus on administrative and clinical transactions, and therefore
provide only a partial view of the actual experience and patient engagement [21]. Recent developments
in healthcare have introduced new types of data, particularly patient-generated health data from remote
monitoring devices and patient experience data [17, 16], but their integration into process mining is
still absent.
      </p>
      <p>Anhang et al.[22] highlight the value of patient experience data for improving healthcare processes
and outcomes. Patient surveys are increasingly used to gather structured feedback on diferent aspects of
care. Gualandi et al.[15] showed that collecting patient-reported data at multiple moments in the patient
journey ofers a more detailed view on patient experience than traditional satisfaction surveys, which
are typically administered at a single point in time. Elliott et al. [14] report consistent improvements
across nearly all dimensions of patient experience following the implementation of systematic hospital
surveys.</p>
      <p>
        In parallel with the growing attention for patient experience data, remote health monitoring
technologies are becoming increasingly important for ensuring continuity of care beyond the hospital setting
[23]. This is particularly evident in the management of atrial fibrillation (AF), where smartphone-based
tools such as FibriCheck have shown promising results. The TeleCheck-AF project, presented by
Gawałko et al.[
        <xref ref-type="bibr" rid="ref13">13</xref>
        ], demonstrated that remote rhythm monitoring via app-based photoplethysmography
(PPG) is technically feasible across multiple healthcare settings, achieving high patient compliance and
positive evaluations from professionals. Beerten et al.[24] confirmed FibriCheck’s usability and patient
engagement in Belgian general practices, and Knaepen et al. [25] showed that remote data from the app
can efectively support teleconsultations.
      </p>
      <p>
        Despite their growing importance, patient experience data and remote monitoring data have not
yet been empirically integrated into process mining analyses within healthcare. Most existing process
mining studies continue to rely on transactional and clinical data from HIS, with little attention given
to the experiential and patient engagement aspects of care [
        <xref ref-type="bibr" rid="ref11">11, 20</xref>
        ]. At the same time, the literature
on patient experience surveys largely focuses on survey design, implementation, and their role in
satisfaction or quality improvement initiatives [15, 14], rather than on integrating this data into process
analytics. Similarly, research on remote monitoring technologies such as FibriCheck primarily addresses
clinical efectiveness, user compliance, and technical feasibility [
        <xref ref-type="bibr" rid="ref13">13, 25, 24</xref>
        ], with limited consideration
of their potential for process-level analysis.
      </p>
      <p>This doctoral research aims to fill that research gap. It investigates how non-traditional data sources,
specifically remote health monitoring and patient experience surveys, can be meaningfully included
in process mining projects. These types of data introduce specific methodological challenges, such as
aligning asynchronous or loosely structured data streams with clinical event logs, dealing with data
quality issues like wearable accuracy, patient persistence, and poor connectivity, as well as handling
subjective and context-dependent input [26, 27, 17]. Particularly in the case of patient feedback,
additional challenges include mapping survey responses to concrete process activities and filtering out
noise [28]. Addressing these challenges is essential to unlock the full potential of these data sources for
process-oriented decision-making in healthcare.</p>
      <p>
        This need is further motivated by Muñoz-Gama et al. [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ], who highlight the importance of analyzing
healthcare processes from the patient’s perspective. They advocate for including patient experiences
and data beyond hospital walls to better understand the care journey through the “patient’s eyes”. Our
focus on remote monitoring and patient-reported experience data responds directly to this call, ofering
complementary views that extend traditional, institution-centered process mining. In line with this,
Erdogan and Tarhan [29] emphasize that healthcare data stem from heterogeneous sources, and that
addressing data integration challenges is essential for the efective application of process mining in
healthcare.
      </p>
    </sec>
    <sec id="sec-3">
      <title>3. Research objectives and methods</title>
      <p>This doctoral research aims to explore how novel data sources can be integrated into process mining.
While process mining has become a mature method for analyzing event data, its potential to incorporate
non-traditional data types such as remote patient monitoring and patient-reported experience measures
remains underexplored. The relationship between these diferent concepts can be found in Figure 1.</p>
      <p>The central research question is: "How can the integration of process orientation and data-driven
decision-making in healthcare be better understood and supported through qualitative insights and
process mining techniques using new data sources?". To address this question, the research is organized
into three interrelated projects. Currently, the first project is nearing completion, while projects two
and three are being co-developed with partner hospitals. Study protocols are under construction in
close collaboration with clinical and data stakeholders.</p>
      <sec id="sec-3-1">
        <title>3.1. Project 1: a qualitative study of Flemish hospital departments to assess the current state, opportunities and challenges of integrating PO and DDDM</title>
        <p>The objective of project 1 is to assess the current state, opportunities and challenges of integrating PO
and DDDM within Flemish hospital departments. Despite the widespread availability of healthcare
data and the growing interest in process orientation, little is known about how these paradigms are
implemented and perceived at the departmental level. This project seeks to fill that gap.</p>
        <p>A qualitative study based on semi-structured interviews with head nurses and medical
department leads will be conducted across multiple hospitals in Flanders. The interviews explore three
central themes: (1) current practices and challenges related to data use in clinical and operational
decision-making, (2) how processes are currently defined, coordinated, and monitored, and (3) perceived
opportunities and barriers for increasing PO and DDDM maturity.</p>
        <p>Interviews are guided by a structured protocol covering both data and process dimensions, and
transcripts are analyzed thematically using an inductive coding approach [30]. The analysis aims to
identify common patterns, diferences across hospital types or departments, and actionable insights to
inform subsequent case studies. To date, all interviews took place and are now being analyzed. This
study forms the contextual basis for project 2 and project 3.</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Project 2: a process mining study using remote monitoring data</title>
        <p>Project 2 explores the integration of remote health monitoring data into process mining analyses. The
case study takes place in a cardiology department where patients are monitored for AF recurrence
after an ablation procedure using a smartphone-based application. The goal is to analyze how patient
behavior and responsiveness of hospital staf unfold in this hybrid care setting.</p>
        <p>The study leverages two main data sources: (1) the smartphone-based application, which captures
daily heart measurements, symptoms and alerts, and (2) the hospital’s electronic health record, which
contains timestamps for clinical actions such as follow-up consultations or medication adjustments.
Process mining techniques are applied to model patient monitoring trajectories, examine response times
to alarms, and analyze behavioral patterns over time, such as measurement adherence and frequency of
symptom reporting.</p>
        <p>We also investigate the methodological and technical challenges of combining patient-generated data
with clinical event logs, such as aligning wearable accuracy, patient persistence, poor connectivity and
lack of integration with electronic medical record systems [26, 27, 17]. The project will deliver both
descriptive insights into monitoring workflows and a set of structured integration steps for applying
process mining to remote health data. The results are co-interpreted with clinical stakeholders to ensure
practical relevance and feasibility.</p>
      </sec>
      <sec id="sec-3-3">
        <title>3.3. Project 3: a process mining study at a hospital that combines event logs with patient experience data</title>
        <p>Project 3 focuses on combining traditional process mining with patient-reported experience data in
a breast cancer care pathway. While patient satisfaction is a key indicator of care quality, it is rarely
analyzed in conjunction with process execution data. This project aims to bridge that gap by integrating
satisfaction scores into process analysis.</p>
        <p>In this case study, we collaborate with a hospital that collects patient satisfaction data at several
touchpoints along the breast cancer care trajectory. These touchpoints include consultations, treatments,
and discharge moments. Using process mining techniques, we reconstruct the patient journey from
event logs and enrich this with satisfaction data to perform a layered analysis. The analysis investigates
how such process diferences relate to variation in patient satisfaction at diferent touchpoints. The
goal is to provide a methodology for adding patient feedback data to process execution data, facing
challenges such as aligning feedback moments with specific process events, filtering out irrelevant or
noisy responses, and preserving the contextual richness [28]. Since surveys are often anonymous, we
are discussing a prospective setup with the hospital to enable linkage. This approach may introduce
social desirability bias, where patients respond less honestly when not anonymous [31]. However, the
project’s main goal is to explore how subjective feedback can be ethically and technically integrated
into process mining analysis. The outcome will be a proof-of-concept approach for linking process data
with patient experience scores, including design principles for future application.</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Conclusion</title>
      <p>The added value of this research lies in expanding the process mining toolbox to include non-traditional
data types, specifically patient-generated data from remote monitoring and patient experience data.
These data streams are increasingly available in modern care settings, yet remain underutilized in
data-driven process analysis [16, 17, 18].</p>
      <p>The first study provides a foundational understanding of the current maturity in PO and DDDM across
Flemish hospitals, identifying the current state, opportunities and barriers. This qualitative insight
guides the case studies that follow. The second project uses remote health monitoring data to evaluate
how patients behave in digital follow-up trajectories. The third project enriches traditional process
models with patient satisfaction data, allowing for layered analyses that connect process variants to
patient-reported outcomes.</p>
      <p>Together, these projects contribute to the theoretical development of process mining methods by
demonstrating how new data types can be structurally embedded in process mining frameworks. They
also provide actionable insights to healthcare practitioners seeking to design more responsive and
patient-centered care pathways.</p>
    </sec>
    <sec id="sec-5">
      <title>Acknowledgments</title>
      <p>This study was supported by the Special Research Fund (BOF) of Hasselt University under Grant No.
BOF24OWB10.</p>
    </sec>
    <sec id="sec-6">
      <title>Declaration on Generative AI</title>
      <p>During the preparation of this work, the author used ChatGPT-4o in order to: paraphrase and reword.
After using this tool/service, the author reviewed and edited the content as needed and takes full
responsibility for the publication’s content.
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