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  <front>
    <journal-meta>
      <issn pub-type="ppub">1613-0073</issn>
    </journal-meta>
    <article-meta>
      <title-group>
        <article-title>Organization Insights through Integrated HIS and RTLS Data: Novel Methods and Applications</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Haroon Tharwat</string-name>
          <email>haroon.tharwat@uhasselt.be</email>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Workshop</string-name>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>UHasselt - Hasselt University, Digital Future Lab, Agoralaan</institution>
          ,
          <addr-line>3590 Diepenbeek</addr-line>
          ,
          <country country="BE">Belgium</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>UHasselt - Hasselt University, Faculty of Business Economics</institution>
          ,
          <addr-line>Agoralaan, 3590 Diepenbeek</addr-line>
          ,
          <country country="BE">Belgium</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>Hospital nursing shortages can lead to significant drawbacks for both patients and nurses, including longer waiting times, missed assessments, delayed responses, and medication errors. Nurses also experience higher stress, increased burnout, and lower job satisfaction. Addressing these challenges requires a deeper understanding of how nursing work is organized in practice. Currently, most insights rely on nurses recording tasks in a Hospital Information System (HIS). While HIS data is context-rich, it is prone to bias and often fails to capture the timing and completeness of nursing activities due to delayed or missing documentation. In contrast, Real-Time Location System (RTLS) data provides an automatically recorded, accurate account of staf and equipment movement, but lacks clinical context and cannot specify the nature of the tasks performed. To date, most research has considered HIS and RTLS data in isolation, limiting the ability to reconstruct a more accurate view of nursing work organization. This doctoral research aims to address this gap by integrating HIS and RTLS data to generate a richer and more accurate nursing task log than either source can provide alone. By combining the strengths of both data types, the resulting unified log serves as a foundation for advanced process mining and analysis, supporting the discovery of actionable insights to improve nursing work organization.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Hospitals worldwide continually face the complex challenge of delivering high-quality care amidst
severe nurse understafing and rising healthcare demands due to aging populations and global health
crises [
        <xref ref-type="bibr" rid="ref1 ref2 ref3">1, 2, 3</xref>
        ]. Nursing staf shortages exacerbate critical issues, including prolonged patient wait
times, increased risk of medical errors, and elevated stress and burnout rates among nurses, ultimately
diminishing patient care quality and workforce satisfaction [
        <xref ref-type="bibr" rid="ref4 ref5">4, 5</xref>
        ].
      </p>
      <p>
        Accurate insights into nursing work organization can help address these challenges by improving
resource allocation, workload distribution, and task coordination [
        <xref ref-type="bibr" rid="ref6 ref7">6, 7</xref>
        ]. Traditional methods for
capturing nursing work organization data (eg., diary keeping and observational studies) ofer contextual
richness but sufer from significant limitations: they are labor-intensive, susceptible to bias (e.g.,
the Hawthorne efect), and typically constrained by incomplete data collection. Incomplete data
collection refers to the fact that not all activities are recorded, key contextual details may be missed,
and documentation is often performed later rather than in real time [
        <xref ref-type="bibr" rid="ref2 ref3 ref8 ref9">8, 9, 3, 2</xref>
        ].
      </p>
      <p>
        A commonly used alternative to manual observation is to leverage Hospital Information System (HIS)
data. HIS data is generated as part of routine hospital operations and consists of entries documented by
healthcare staf during clinical work, resulting in event logs that contain information about activities
performed, the patient involved, responsible staf, and the time of registration [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. However, similarly
to traditional methods for capturing nursing work organization data, HIS recordings often exhibit
inaccuracies due to delayed entries, batch documentation practices, and omitted tasks, resulting in
fragmented and temporally imprecise data [
        <xref ref-type="bibr" rid="ref10 ref11 ref12 ref4">10, 11, 4, 12</xref>
        ].
      </p>
      <p>CEUR</p>
      <p>ceur-ws.org</p>
      <p>
        In addition to HIS data, Real-Time Location Systems (RTLSs) represent an alternative data source
that continuously captures the precise spatial and temporal information of nurses and equipment as
they move through the ward. Unlike HIS data, which provides clinical and task-related details, RTLSs
data does not indicate what activity is being performed; they only record where and when movement
occurs. This absence of explicit clinical context means that inferring specific nursing tasks directly
from RTLS data alone is challenging [
        <xref ref-type="bibr" rid="ref13 ref6">6, 13</xref>
        ].
      </p>
      <p>
        While both HIS and RTLS data sources have been explored in isolation for process mining in healthcare,
each provides a distinct view of nursing work [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. HIS data contributes to detailed clinical context
and task-specific information, but lacks location or precise timing. RTLSs, on the other hand, capture
accurate movements and presence information, yet do not capture the types of activities performed.
By integrating these two data sources, it becomes possible to obtain a more complete, reliable, and
accurate view of nursing work organization than would be achievable by analyzing either data source
in isolation [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ].
      </p>
      <p>
        This doctoral research proposes a novel approach to systematically integrate HIS and RTLS data. The
integration aims to semi-automatically reconstruct a detailed, unified nursing task log by combining
clinical activity data from the HIS with precise timing and location data from the RTLS. This unified
nursing log enables the identification and analysis of complex work organization patterns – including
when and where multitasking occurs, how nurses collaborate in teams, and how activities are distributed
across time and space in the ward [
        <xref ref-type="bibr" rid="ref14 ref4">14, 4</xref>
        ]. The two fundamental challenges addressed in this research
are: (i) developing a robust, semi-automated method for integrating HIS and RTLS data into a nursing
task log, and (ii) extracting and visualizing actionable insights from the integrated log to support
improvement of nursing work organization [
        <xref ref-type="bibr" rid="ref15 ref16 ref4">4, 15, 16</xref>
        ]. By allowing for a more detailed analysis of
the flow of nurses, this research helps identify bottlenecks, reduce ineficiencies, and optimize staf
allocation. These practical tools for work organization analysis can directly inform evidence-based
management decisions and support continuous improvement in patient care.
      </p>
    </sec>
    <sec id="sec-2">
      <title>2. Related Work</title>
      <p>
        Process mining, a prominent field in Business Process Management (BPM), has increasingly focused on
healthcare, leveraging HIS data to analyze clinical work organization and support process improvement
[
        <xref ref-type="bibr" rid="ref17">17</xref>
        ]. Applications include identifying ineficiencies in care delivery, optimizing resource allocation,
improving patient flow, and supporting regulatory compliance [
        <xref ref-type="bibr" rid="ref11 ref18">11, 18</xref>
        ]. For example, Agostinelli et
al.[19] employed process mining to analyze care pathways in an Italian hospital, yielding actionable
insights that informed management decisions and led to a reduction in patient abandonment rates.
Similarly, Kurniati et al.[20] combined HIS event logs with user access data to examine system usage
during chemotherapy treatments, revealing patterns in clinician interactions with digital tools and
their impact on care delivery. Comprehensive surveys of healthcare process mining studies [
        <xref ref-type="bibr" rid="ref17">17</xref>
        ]
consistently reveal key data quality challenges in HIS data. Common issues include missing data, such
as absent timestamps, activity labels, or patient identifiers, which can lead to incomplete or fragmented
process models [21, 22]. Incorrect or inconsistent entries, such as erroneous timestamps, duplicated
events, or mismatched patient journey IDs, often arise from manual entry errors or system integration
problems and can mislead analyses [23, 21]. Additionally, imprecise or irrelevant data, such as vague
or overlapping timestamps, or system-generated events unrelated to clinical work organization, can
further compromise the reliability of process mining results [21]. These limitations underscore the
importance of robust data quality management and the use of complementary data sources in healthcare
process mining.
      </p>
      <p>To address these HIS data quality limitations, recent research proposes leveraging RTLS data as
an alternative or complementary source for process analysis. A growing body of work demonstrates
that integrating RTLS data with process mining techniques ofers substantial benefits for analyzing
and optimizing healthcare work organization. For example, Araghi et al. [24] developed a method
for visualizing and diagnosing patient pathways using RTLS data, enabling the extraction of valuable
operational insights for healthcare decision-makers. In surgical settings, RTLS-driven process mining
has been applied to analyze thousands of patient journeys, optimize perioperative procedures, and
reduce ineficiencies, providing clear real-world value [ 25]. RTLSs enable the automatic and unobtrusive
collection of high-resolution location data on patients, staf, and equipment, supporting the
reconstruction of detailed care pathways without reliance on manual data entry [26, 25]. Collectively, these studies
provide strong evidence that process mining with RTLS data is an efective and practical approach
for advancing operational eficiency and quality assurance in healthcare environments. Nevertheless,
RTLSs data alone have limitations, notably the lack of information about the specific clinical activities
being performed.</p>
      <p>
        While prior research has explored process mining using either HIS or RTLS data in isolation, the
systematic integration of these sources remains underexplored, mainly in the BPM literature. For
example, Osman et al. [27] investigated the integration of RTLSs with HISs data in an emergency and
trauma department, focusing primarily on patient pathways and waiting times, but not on the unique
complexities of nursing work organization. Yet, integration is arguably even more essential for nursing,
as nurses perform a diverse array of tasks, such as rounds, documentation, and direct patient care, that
are often only partially or inconsistently recorded in information systems. Building on this identified
gap, Martin (2019) lays the conceptual foundation for this doctoral research by systematically examining
both the opportunities and the methodological challenges of combining RTLS and HIS data. Notably,
Martin (2019) explicitly calls for practical methods to enable such integration, highlighting the need for
innovative approaches tailored to the realities of healthcare practice [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. This doctoral research directly
responds to that call by developing and validating a systematic approach for merging RTLS and HIS
data. The resulting unified event log of nursing work enables a more comprehensive analysis of work
organization. It supports targeted process optimization, addressing both the challenges outlined and
the conceptual vision set out by Martin (2019).
      </p>
      <p>In summary, although previous research has explored process mining with diferent data sources,
there is currently no established method for systematically integrating HIS and RTLS data to reconstruct
complete nursing task logs. This research directly addresses this gap by developing and validating a
novel, semi-automated footprint-based approach for integrating HIS and RTLS data, thereby enabling
more accurate reconstruction and analysis of nursing work organization.</p>
    </sec>
    <sec id="sec-3">
      <title>3. Research Objectives</title>
      <p>Given the limitations identified in prior literature regarding the accurate reconstruction of nursing
work organization from isolated data sources, this doctoral research addresses two primary research
objectives:
1. Integration of HIS and RTLS Data: Develop a robust, semi-automated approach to integrate
heterogeneous data sources (HIS &amp; RTLS) into a unified nursing task log. By overcoming the
individual limitations of each source, the integrated log will provide more accurate timestamps,
richer clinical context, and precise location information. This integration is essential for reliably
reconstructing nursing tasks and activities, which are often incompletely captured in existing
systems due to documentation delays, missing data, or sensor inaccuracies.</p>
      <p>This unified log aims to overcome individual limitations by providing more accurate timestamps,
context, and location identification.
2. Work Organization Pattern Analysis and Visualization: Leverage the unified nursing task log
to systematically identify, analyze, and visualize key patterns in the organization of nursing work.
The objective is to provide actionable, data-driven insights that support the improvement and
optimization of nursing work organization. By revealing complex patterns such as multitasking,
collaboration, and temporal-spatial allocation of resources, these analyses aim to inform
evidencebased management decisions and support practical improvements in work organization eficiency
and patient care.</p>
    </sec>
    <sec id="sec-4">
      <title>4. Research Methodology</title>
      <p>This doctoral research addresses two primary methodological challenges to achieve its objectives.</p>
      <sec id="sec-4-1">
        <title>4.1. Challenge 1: Robust Integration of HIS and RTLS Data</title>
        <p>To more accurately reconstruct nursing work organization, this research is developing and iteratively
validating a structured, semi-automated method that leverages domain knowledge to integrate HIS and
RTLS data systematically. The input consists of structured HIS records, including task labels, nurse
and patient identifiers, and timestamps documenting task completions (e.g., medication administration,
vital sign checks), as well as continuous RTLS logs that capture the real-time locations of nurses
and medical equipment. The integration process begins by defining task footprints, which translate
domain expertise into concrete criteria: specifying which resources must be present, the relevant
spatial constraints (e.g., patient rooms), and the required temporal alignment. For example, the task
”Medication Administration” may be operationalized as a nurse and medication cart co-located in the
patient’s room for a minimum duration, temporally aligned with a corresponding HIS timestamp. A
footprint-based matching algorithm then systematically scans the HIS and RTLS data to identify events
that satisfy these criteria—extracting relevant HIS entries, filtering RTLS data by nurse identifiers,
confirming co-location and temporal overlap within set tolerance windows, and ultimately generating
a unified task log enriched with semantic and spatial-temporal detail. The method will be rigorously
validated using synthetic data generated from a discrete-event simulation environment, with systematic
performance assessment using precision, recall, F1-score, and accuracy. Looking ahead, future iterations
will explore more data-driven approaches, including the use of machine learning to detect frequently
occurring work organization patterns directly from the integrated data.</p>
      </sec>
      <sec id="sec-4-2">
        <title>4.2. Challenge 2: Analysis and Visualization of Work Organization Patterns</title>
        <p>Once a unified nursing task log is generated, advanced process mining techniques and data analytics
methods will be applied to reveal underlying work organization patterns. Specific patterns to be explored
include multitasking behaviors, inter-nurse collaboration, and temporal distribution of activities. The
output will consist of interactive, intuitive visualizations explicitly designed to communicate actionable
insights to nurses and hospital administrators. These visualizations will be developed iteratively in
collaboration with clinical stakeholders, ensuring relevance, clarity, and practical usability.</p>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>5. Preliminary Results</title>
      <p>The current stage of this doctoral research focuses on developing, evaluating, and refining a robust data
integration pipeline for synthesizing HIS and RTLS data into a nursing task log. Given the practical
limitations in obtaining the ground truth in a real-life setting, synthetic data was generated.</p>
      <sec id="sec-5-1">
        <title>5.1. Simulation-based Synthetic Data Generation</title>
        <p>A discrete-event simulation model (built using the SimPy framework) was developed to systematically
generate realistic synthetic datasets representing nursing tasks in a hospital ward. First, an idealized
“ground truth” nursing task log is created, accurately capturing the start and end times of each task, the
resources involved (e.g., specific nurses and equipment), patient identifiers, and explicit task labels (e.g.,
medication administration, vital sign checks). Second, corresponding idealized HIS and RTLS logs are
derived from this perfect log, reflecting exact clinical documentation and precise real-time movements
with no data quality issues. Third, realistic imperfections typical of actual hospital data are introduced
into these logs. Specifically, the HIS logs incorporate delayed documentation (up to 10 minutes) and
aggregated or missing entries ( 10% omission), while the RTLS logs include intermittent signal loss
(5% dropout), temporal jitter (±2 minutes), and occasional incorrect nurse location assignments. This
structured synthetic data generation approach provides a controlled environment for evaluating and
refining the footprint-based integration method.</p>
      </sec>
      <sec id="sec-5-2">
        <title>5.2. Initial Evaluation and Insights</title>
        <p>The footprint-based matching algorithm is currently under iterative development. It integrates HIS
and RTLS data by leveraging domain-driven task footprints that explicitly encode clinical knowledge
into structured definitions (resource requirements, spatial constraints, and temporal alignment criteria).
Preliminary evaluations with these synthetic datasets provide controlled benchmarks and valuable
feedback that directly inform ongoing methodological refinements.</p>
        <p>Initial evaluation results, focusing on standard metrics such as precision, recall, and F1-score, highlight
clear strengths and specific areas for improvement. For instance, the algorithm demonstrates promising
precision in correctly identifying task matches but faces challenges with recall, underscoring the need for
improved sensitivity and robustness against data imperfections. These findings are actively guiding the
next development iterations, including adaptive temporal matching techniques and improved handling
of RTLS data variability. Moreover, these preliminary insights underscore the value of the structured
synthetic approach as both a methodological tool and a guiding mechanism for refining the algorithm
toward reliable real-world applicability.</p>
      </sec>
    </sec>
    <sec id="sec-6">
      <title>6. Next Steps</title>
      <p>These initial findings provide a solid foundation for targeted improvements and validation of the
integration approach. Moving forward, the matching algorithm will be refined by incorporating adaptive
temporal alignment strategies, enabling more robust identification of nursing tasks despite variable
documentation delays and intermittent RTLS signals. The task footprint library will be expanded to
represent increasingly complex and collaborative clinical scenarios, ensuring the integration approach
remains applicable to real-world nursing workflows. Additionally, the method’s robustness to common
data imperfections (e.g., missing entries or sensor inaccuracies) will be improved by developing enhanced
error-handling logic. All methodological improvements will be thoroughly validated using synthetically
generated HIS and RTLS datasets, with performance evaluated through quantitative metrics (e.g.,
precision, recall, F1-score).</p>
      <p>Subsequently, the development of pattern analysis and visualization techniques will commence,
utilizing the enriched task log to derive actionable insights into nursing work organization and to design
intuitive visual representations for end-users. Through these concrete next steps, this research aims to
deliver a scalable and clinically relevant framework for more accurate, data-driven analysis of nursing
work organization.</p>
    </sec>
    <sec id="sec-7">
      <title>7. Conclusion</title>
      <p>This doctoral research proposes a structured, semi-automated approach to integrate HIS and RTLS
data for reconstructing unified nursing task logs. By leveraging domain-driven task footprints, the
methodology systematically combines complementary sources, addressing common limitations of
existing hospital data and enabling a more complete and accurate analysis of nursing work organization.
Initial synthetic data evaluations confirm the promise of the approach and highlight specific challenges,
particularly in terms of sensitivity to missing and imprecise data. These insights directly inform
ongoing development, guiding further algorithmic refinement and comprehensive validation in
realworld hospital settings. Ultimately, this work aims to provide a robust methodological foundation
for process mining and the optimization of nursing work organization, supporting more efective and
data-driven care delivery.</p>
    </sec>
    <sec id="sec-8">
      <title>Acknowledgments</title>
      <p>This work was supported by Research Foundation Flanders (FWO) under Grant Number G0A4524N.</p>
    </sec>
    <sec id="sec-9">
      <title>Declaration on Generative AI</title>
      <p>This author has employed Generative AI tools (e.g., ChatGPT) solely for grammar correction and
language refinement. No AI-generated text contributed to the scientific content or analysis of the paper.
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