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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>European Journal of
Information Systems</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.1080/0960085X.2018.1458066</article-id>
      <title-group>
        <article-title>FEDWELL: Life-long federated user and mental modeling for health and well-being</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Sabine Janzen</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Prajvi Saxena</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Cicy Agnes</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Muhammad Ebad Ullah Khan</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Amr Gomaa</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Michael Feld</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Andre Zenner</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Pascal Lessel</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Julian Wolter</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Florian Daiber</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Rafael Math</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Niko Kleer</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Tim Schwartz</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Antonio Krueger</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Wolfgang Maass</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>German Research Center for Artificial Intelligence</institution>
          ,
          <addr-line>DFKI</addr-line>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Saarland University</institution>
          ,
          <country country="DE">Germany</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2018</year>
      </pub-date>
      <volume>27</volume>
      <issue>2018</issue>
      <fpage>129</fpage>
      <lpage>139</lpage>
      <abstract>
        <p>Adaptive and personalized AI systems in healthcare rely on user-specific and contextual information to provide support. However, incomplete, unreliable, and outdated data prevents both patients experiencing illness, pain, or cognitive impairment, as well as therapists, in making proper and informed decisions. Patients specifically may not have the knowledge to comprehend complex medical information, or efectively communicate symptoms. AIdriven mental models and user models can bridge these cognitive gaps, ensuring personalized and efective patient care. The FedWell research project (09/2023-08/2026), funded by the Federal Ministry of Education and Research (BMBF), explores the integration of artificial mental models (AMMs) and user models from various sources into adaptive AI systems to assist patients in decision-making. The project focuses on two key applications: rehabilitation support after knee/hip surgery and treatment decision assistance for patients with cognitive impairments (e.g., multiple sclerosis, dementia). FedWell employs a combination of structured surveys, contextual data collection, and AI techniques to model patient behavior, attitudes, and intentions. A decision support system MENTALYTICS is developed from fine-tuned large language models (LLaMA-2, LLaMA-3, Mistral, Phi-3), that employs AMMs. By the end of the project, FedWell aims to deliver robust AMMs capable of representing patient beliefs and decision-making processes, ultimately guiding them toward treatment options that best fit their individual needs.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;Personalized healthcare</kwd>
        <kwd>Adaptive AI-system</kwd>
        <kwd>Artificial Mental Model</kwd>
        <kwd>Decision support system</kwd>
        <kwd>Rehabilitation</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        In the field of prevention and rehabilitation, adaptive and personalized systems based on artificial
intelligence (AI) methods can play a decisive role as supporters of patient-centered care [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. In 2023,
1,886,876 patients with an average length of stay of 25.5 days were treated in a preventive care or
rehabilitation facility in Germany. The majority of full inpatients (approx. 550,000) were treated
for musculoskeletal diseases and injuries, e.g., osteoarthritis. The success of medical rehabilitation
depends crucially on good cooperation between the patient, doctor and physiotherapist as well as the
patient’s willingness to actively participate in a structured, often painful program [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]. However, patients
exhibit cognitive limitations in situations characterized by illness, pain and medical decisions. As a
result, informed decision-making, understanding of complex medical issues and efective articulation
of symptoms and individual concerns are not always possible [
        <xref ref-type="bibr" rid="ref3 ref4 ref5 ref6">3, 4, 5, 6</xref>
        ]. Up to 30% of patients in
rehabilitation facilities can be characterized as linguistically impaired; i.e. they are unable to express
themselves appropriately due to the aforementioned cognitive limitations, migration backgrounds or
psychological problems [7, 8, 9, 10]. In addition, patients often experience conflicting goals during
rehabilitation that are not immediately visible to doctors, physiotherapists and psychologists. On the
one hand, there is a desire to complete rehabilitation quickly and successfully; on the other hand,
there are conflicting motives, such as the perceived relief in rehab in case of excessive demands at
home [11, 12]. One potential approach is the use of artificial mental models in therapeutic contexts and
associated AI systems to improve personalized patient care and therapy outcomes [13, 14, 15]. FEDWELL
is an ongoing research project funded by the German Federal Ministry of Education and Research
(BMBF) (09/2023 - 08/2026) that investigates federated personalized user modeling (UM) and artificial
mental models (AMMs) in adaptive AI systems to support patients for making informed decisions
under risk conditions. Recognizing the cognitive impairments of patients in healthcare situation as
described, we will design, develop, and evaluate AMM-powered AI systems tailored for both personal
and professional applications, ensuring respectful treatment tailored to the user’s behavior and meeting
unique needs and challenges faced by the involved patients. This includes the evaluation of the adoption
of such systems by users, i.e., patients, therapists and medical doctors, including the validation of their
impact. The project consortium consists of partners from research and healthcare that take diferent
roles in the project: end users from healthcare (rehabilitation hospital) and research &amp; development
(German Research Center for Artificial Intelligence (DFKI)). FEDWELL investigates the application
of AMM-powered AI systems in two primary use cases: post-knee/hip surgery rehabilitation support
and therapy decision support for patients with compromised decision-making abilities (e.g., multiple
sclerosis, dementia).
      </p>
      <p>In this paper, we present an overview of the FEDWELL project, including its objectives, work
packages and expected outcomes. We will discuss the role of information systems in FEDWELL,
especially focusing on the current state of work and first results in form of a decision support system in
the domain of rehabilitation.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Project objectives</title>
      <p>Objective of the FEDWELL project is to design and develop adaptive, personalized AI systems that
enhance decision-making by patients, therapists and medical doctors by leveraging UM and AMMs.
FEDWELL seeks to address the cognitive limitations and communication challenges faced by patients —
particularly those recovering from orthopedic surgeries or sufering from cognitive impairments — by
constructing AI systems that can understand, anticipate, and adapt to users’ mental states, behaviors,
and individual preferences. By integrating real-time feedback and contextual patient data into UM and
AMMs, FEDWELL aims to enable continuous personalization and update of the models. With focus on
two use cases — post knee/hip surgery rehabilitation and therapy decision assistance for cognitively
impaired patients — the project aspires to deliver AI-powered systems that foster patient autonomy and
support more informed treatment choices.</p>
      <p>
        The term mental model stems from cognitive science. Mental models are cognitive frameworks
that people use to understand and navigate their environment, i.e., the world that surrounds them
[16, 17, 18, 19]. A patient’s mental model reflects their assumptions about the target system, i.e., the
environment they interact with, e.g., assumptions about their therapy and rehabilitation progress
[20, 17, 21]. Since the patient’s mental model is implicit and therefore unknown, the approach of
AMMs is to create a conceptual model of the patient’s mental model that anticipates it in form of a
meta-representation. Cognitive mental models are conceptually similar to world models in AI [22].
These refer to the internal representation of a system’s environment that it uses to understand, predict
and interact with the world around it. Essentially, a world model allows an AI system to simulate
possible outcomes of its actions, anticipate changes and adapt its behavior accordingly. Both mental
models and world models serve the purpose of internally simulating the outside world to enable adaptive
and goal-oriented behavior. However, mental models are formed through a combination of congenital
mechanisms, learning and social influences, while world models are explicitly designed and trained
through data and algorithms. AMMs can be understood as world models that anticipate unknown
mental models of patients. The use of AMM in rehabilitation can promote the efectiveness of therapies,
support improved decision-making processes and help to identify and correct knowledge gaps and
misconceptions of patients [18]. Existing research emphasizes the need to accurately capture and
understand mental models, especially in therapy and rehabilitation scenarios [23, 24, 20, 25], which
are essential but challenging after knee injury or surgery. Even minor restrictions have a significant
impact on mobility. After injuries such as cruciate ligament tears or meniscus damage, patients must
gradually regain strength, mobility and stability [
        <xref ref-type="bibr" rid="ref7">26</xref>
        ]. One of the biggest challenges is the slow progress.
Frustration arises when freedom from pain or full mobility is not achieved immediately. The right
balance between strain and rest is crucial: too much strain can interfere with healing, too much rest
leads to stifness or muscle weakness [
        <xref ref-type="bibr" rid="ref8">27</xref>
        ]. Pain can also reduce motivation, causing patients to avoid
important exercises. Psychological factors, such as fear of re-injury, also play a role [
        <xref ref-type="bibr" rid="ref9">28</xref>
        ]. An AMM
for a patient undergoing knee rehabilitation can capture how she perceives her injury, the recovery
process and her environment. The model combines physical, psychological and environmental factors.
Physically, it includes the condition of the knee, pain levels and movement restrictions. It recognizes
relationships between movement and pain, e.g., that stretching reduces stifness. Expectations of healing
time are also taken into account. Psychologically, the AMM integrates beliefs about the ability to recover,
influenced by previous experiences and confidence in the rehabilitation process. Optimistic patients see
progress, while discouraged people perceive the therapy as slowed down. Environmental factors such
as family support or work commitments also have an influence. The AMM maps the patient’s beliefs,
behavior and progress. It can therefore predict how they will react to exercises and what fears they
have. This enables therapists to develop personalized strategies to increase motivation and optimize
rehabilitation success.
      </p>
      <p>
        The project has four work packages (aside of the ongoing project management that applies at all
time). WP1 (Federated User Modeling Concepts and Platform) is about developing an architecture
and platform for federated UM. Federated UM refer to systems where user identities are managed
across multiple independent systems or nodes, rather than being stored and processed by a single
service. It will serve as basis for the use cases of the project, although the specified architecture is
generalizable and applicable beyond the scope of the domains of interest in the project. Results of
this phase will be introduced in section 3.1. WP2 (User and Mental Model Design) intends to specify
and deploy AMMs. Here, a research design based on a Design Science approach was specified for the
investigation of AMM in AI systems in the healthcare sector [
        <xref ref-type="bibr" rid="ref10">29</xref>
        ]. The research design comprises four
iterative phases: Elicitation, Individualization, Action and Transfer. Aim of the elicitation phase was to
generate a non-discriminatory and bias-free, domain-specific basic model of an AMM in the field of
knee rehabilitation. The AMM was trained with LLaMA-2 (7B), LLaMA-3 (8B, 70B), GPT-4.o-mini, Phi-3
and Mistral (7B) in a two-stage approach combining systematic data scraping and an empirical user
study (n=116). The evaluation of the AMM included classification tasks, such as predicting whether a
patient can perform an exercise and predicting her expected pain or efort. Further evaluation of the
AMM focused on minimizing bias, ensuring demographic fairness in predictions, and using confidence
probabilities to increase the reliability of predictions. Results of this phase will be introduced in section
3.2. Based on the results of WP1 and WP2, in WP3 (Multimodal Interface Presentation), a multimodal
interface for end users, means patients, therapists and medical doctors will be developed. Finally, the
objective of WP4 (Feedback-based Adaptation) is to measure the user adoption of the specified, adaptive
AI-system supported by AMMs and UM.
      </p>
    </sec>
    <sec id="sec-3">
      <title>3. Current status and intermediate results</title>
      <sec id="sec-3-1">
        <title>3.1. Federated user model platform architecture (WP1)</title>
        <p>
          Existing literature highlights systems similar to our Federated User Model Platform, such as
MYRROR [
          <xref ref-type="bibr" rid="ref11">30</xref>
          ], MyrrorBot [
          <xref ref-type="bibr" rid="ref12">31</xref>
          ], and HELENA [
          <xref ref-type="bibr" rid="ref13">32</xref>
          ]. MYRROR is a holistic UM system that merges
data from social networks, smartphones, and FitBit devices using NLP and machine learning to infer
user characteristics. However, it lacks incremental model adaptation and does not distinguish between
a user’s AMM and the system-sided user model. MyrrorBot acts as a Personal Digital Assistant for
personalized online services; but relies on heuristics for UM, limiting adaptive machine learning-based
approaches. HELENA focuses on lifelong health UM, but does not account for outdated information.
The proposed architecture aims to address these limitations by enabling adaptable, continually learning
components that interact through RESTful APIs to update information and models Figure 1. The
architecture consists of several distributed nodes and shared platform services. Nodes are connectors
to various data sources (e.g., dialogue system, user’s smartphone, devices for measuring physiological
parameters, social media accounts, etc.), which continuously collect data about diferent users, annotate
them (e.g., patient’s name, location, time, confidentiality, etc.), and store them in their local storage.
Out of this input (symbolic data, sub-symbolic data, ML models), the platform will generate
patientspecific UM, that can be queried by an adaptive system in order to generate personalized output. While
data is collected and updated continuously, several platform services (e.g., data inconsistency checks,
re-training of ML models, etc.) need to be executed regularly to enable up-to-date query results. Each
node stores the data of the connected sources locally while providing separated repositories for raw
data (e.g., generated by a sensor), ontological data, and ML models. The platform services can address
individual data sets of each connected node through a REST API by using a URL to read and write their
values.
        </p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Decision support system MENTALYTICS (WP2)</title>
        <p>
          As mentioned before, objective of WP2 was the design of AMMs. Therefore, a research design based
on a Design Science approach was implemented that consisted of four phases. Aim of the first phase
- elicitation was the generation of a non-discriminatory and bias-free, domain-specific basis model
of an AMM in the field of knee rehabilitation. As such a model requires large amounts of data in
order to identify patterns, correlations and variations in the inputs and to develop generalization
capability, this phase included indirect observation of patients to create a large data set by means of a
two-stage approach consisting of systematic data scraping and an empirical user study (n=116). The data
scraping strategy was implemented for indirect observation, targeting conversations between patients,
physiotherapists, and doctors, along with curated articles on relevant physiotherapy topics. This yielded
67,000 conversations and 7,000 articles, with 65% discussing knee/leg physiotherapy, 15% specific
methods, and 21% news topics. After preprocessing and filtering using Named Entity Recognition and
clustering [
          <xref ref-type="bibr" rid="ref14">33</xref>
          ], a focused dataset (n=4364) was derived, comprising 2,321 conversations and 2,043 articles
categorized into four clusters: therapies, clinical picture, progression, and diagnostics. The second part
of the indirect observation consisted of conducting an empirical study with 116 participants. The aim of
the study was to compare the efort expected and actually perceived by the participants during sports
exercises with their personality traits, medical history and psychosocial factors. Participants completed
a digital questionnaire and performed video-guided exercises (e.g., squats, calf raises) before rating their
perceived efort and pain, allowing us to compare expected and actual exertion. Data were collected
using Likert, interval, and nominal scales covering demographics, psychosocial and physical activity
factors, medical history, personality traits (TIPI) [
          <xref ref-type="bibr" rid="ref15">34</xref>
          ], and pain ratings (NRS) [
          <xref ref-type="bibr" rid="ref16">35</xref>
          ]. Notably, 46.6% had
prior surgeries, with only 27% fully adhering to rehabilitation plans. A 40% gap was observed between
expected and perceived exertion. For the training of the basis model with the indirect observation data,
a multi-stage process consisting of (1) selection of pre-trained machine learning models, (2) evaluation
of the performance of the selected models in combination with the given data, and (3) fine-tuning
of the models was carried out. Large, pre-trained large language models (LLMs) were selected for
training: LLaMA-2 (7B) [
          <xref ref-type="bibr" rid="ref17">36</xref>
          ], LLaMA-3 (8B, 70B) [
          <xref ref-type="bibr" rid="ref18">37</xref>
          ], GPT-4.o-mini [
          <xref ref-type="bibr" rid="ref19">38</xref>
          ], Phi-3 [
          <xref ref-type="bibr" rid="ref20">39</xref>
          ], Mistral (7B) [
          <xref ref-type="bibr" rid="ref21">40</xref>
          ].
The evaluation of the AMM included classification tasks, such as predicting whether a patient could
perform an exercise and predicting her expected pain or exertion. Further evaluation of the AMM
focused on minimizing bias, ensuring demographic fairness in the predictions, and using confidence
probabilities to increase the reliability of the predictions [
          <xref ref-type="bibr" rid="ref22 ref23 ref24 ref25">41, 42, 43, 44</xref>
          ]. The resulting basis AMM model
is represented by the pre-trained LLaMA-3 (8B) model after fine-tuning, which was adjusted for bias
and hallucinations and achieved 94% accuracy in predicting pain scores for specific patients. Thus, it
outperformed larger models such as LLaMA-3 (70B), which showed significant performance degradation
due to overfitting and reduced generalization. The results show that LLMs can serve as efective
basis models for AMMs. The resulting AMM basis model was integrated into the decision support
system - MENTALYTICS - a tool for medical doctors and therapists in knee rehabilitation that provides
predictions of patients’ expectations regarding the expected pain and efort of physical exercises in
their rehabilitation1. Additionally, the system features a conversational AI assistant, enabling doctors
and physiotherapist to gain further insights and explainations through interactive discussions.
        </p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Relevance of project for CAiSE</title>
      <p>
        The research project FEDWELL is relevant to the International Conference on Advanced Information
Systems Engineering (CAiSE) due to its innovative approach to integrate advanced UM techniques and
AMM into the design of personalized information systems in the healthcare domain. By focusing on
federated UM and AMMs, FEDWELL contributes to the growing body of research that explores
contextaware, adaptive, and user-centric information systems. FEDWELL addresses complex challenges in
medical rehabilitation where user requirements are diverse, decision-making is impaired, and therapeutic
processes are sensitive to individual behavior and motivation. The project exemplifies how advanced
engineering of information systems can bridge the gap between technical sophistication and
humancentered design, especially when supporting vulnerable user groups under high-risk, emotionally
charged, and ethically complex conditions. Furthermore, the project’s commitment to federated learning
paradigms and privacy-preserving data processing reflects critical advancements in system architecture
1Screencast of MENTALYTICS: https://youtu.be/c6eKn5Yk16A?feature=shared
and distributed AI, aligning with CAiSE’s interest in secure, trustworthy, and decentralized information
systems. By designing AMM-powered systems based on a Design Science Approach [
        <xref ref-type="bibr" rid="ref26">45</xref>
        ] and validating
their impact in real-world rehabilitation contexts, FEDWELL contributes valuable insights into system
evaluation methodologies, user adoption, and socio-technical integration.
      </p>
    </sec>
    <sec id="sec-5">
      <title>5. Conclusion and future work</title>
      <p>The FEDWELL project addresses a critical gap in rehabilitation by developing adaptive, AI-driven
systems that account for patients’ cognitive limitations, linguistic impairments, and conflicting therapeutic
goals. By leveraging federated personalized user modeling and artificial mental models, FEDWELL aims
to support more informed, individualized, and ethically aware decision-making processes in medical
contexts. Initial applications focus on post-surgical rehabilitation and therapy support for patients
with compromised decision-making capacity, with active involvement from both clinical and research
stakeholders. In future work, we will further refine AMM-supported decision support systems, expand
their applicability to broader patient groups in clinical settings, and rigorously evaluate their impact on
therapy outcomes, user experience, and interdisciplinary cooperation in healthcare settings. This will
also include the integration of further heterogeneous data sources, e.g., sensor data, patient-reported
outcomes, and clinical observations, to improve the model’s robustness and responsiveness. Emphasis
will also be placed on further developing explainability and transparency into system design to foster
trust and acceptance among patients and professionals.</p>
    </sec>
    <sec id="sec-6">
      <title>Acknowledgments</title>
      <p>This work was partially funded by the German Federal Ministry of Education and Research (BMBF)
under the contract 01IW23004.</p>
    </sec>
    <sec id="sec-7">
      <title>Declaration on generative AI</title>
      <p>During the preparation of this work, the author(s) used GPT-4 and Grammarly in order to: Grammar
and spelling check. In addition, large language models such as LLaMA-2, LLaMA-3, Mistral, and Phi-3
were employed for fine-tuning and experimentation purposes within the scope of this study. After
using these tool(s)/service(s), the author(s) reviewed and edited the content as needed and take(s) full
responsibility for the publication’s content.
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