<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD v1.0 20120330//EN" "JATS-archivearticle1.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>on blockchain and adaptive compression⋆</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Waldemar Wójcik</string-name>
          <email>waldemar.wojcik@pollub.pl</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Pavlo Yakovyshen</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Stanislav Tuzhanskyi</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Politechnika Lubelska</institution>
          ,
          <addr-line>Nadbystrzycka 38A, 20-618 Lublin</addr-line>
          ,
          <country country="PL">Poland</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Vinnytsia National Technical University</institution>
          ,
          <addr-line>Khmelnytske shose 95, 210212 Vinnytsia</addr-line>
          ,
          <country country="UA">Ukraine</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2026</year>
      </pub-date>
      <abstract>
        <p>Telemedicine systems are revolutionizing healthcare by enabling remote diagnostics, consultations, and monitoring, particularly in regions with limited access to medical services. In low-resource rural areas, where infrastructure is weak and network bandwidth often does not exceed 20 kbps, telemedicine becomes a key tool to address healthcare inequalities. However, challenges such as data vulnerability to cyberattacks, low bandwidth, and high power consumption of wearable devices hinder its progress. This article proposes a hybrid model that integrates permissioned blockchain (Hyperledger Fabric) for secure medical data management, adaptive compression based on a convolutional neural network (CNN) to optimize bandwidth usage, and the LoRa protocol for energy-efficient long-range communication. Simulations conducted in MATLAB and NS-3 demonstrate a 25% reduction in data transmission latency, 30% lower energy consumption, and 100% resilience against cyberattacks compared to traditional methods. The model was tested on synthetic datasets (ECG, video streams, text reports) and demonstrated scalability for up to 500 devices within the network. The results are particularly relevant for low-resource regions where access to healthcare is limited due to poor infrastructure. The proposed solution offers a cost-effective and scalable platform for global telemedicine systems, contributing to the digitalization of healthcare.</p>
      </abstract>
      <kwd-group>
        <kwd>eol&gt;Telemedicine</kwd>
        <kwd>blockchain</kwd>
        <kwd>adaptive compression</kwd>
        <kwd>CNN</kwd>
        <kwd>LoRa</kwd>
        <kwd>energy efficiency</kwd>
        <kwd>data security</kwd>
        <kwd>1</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Telemedicine has emerged as a transformative tool in modern healthcare, enabling remote
consultations, diagnostics, and monitoring through information and communication technologies
(ICT) [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ]. According to the World Health Organization (WHO), the adoption of telemedicine has
reduced healthcare costs by 15–20% and significantly improved access to medical services in
remote areas [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]. In low-resource rural regions, where network bandwidth often does not exceed 20
kbps and the nearest hospital may be tens of kilometers away, telemedicine plays a critical role in
reducing disparities in access to healthcare services [
        <xref ref-type="bibr" rid="ref3">3</xref>
        ].
      </p>
      <p>
        However, the implementation of telemedicine faces three major challenges that the authors
have analyzed in their previous work [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]. First, medical data transmitted over networks is
vulnerable to cyberattacks, such as data breaches and ransomware, posing a serious threat to
patient privacy [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ]. Second, low bandwidth in rural areas hinders the transmission of large data
volumes, including video streams and high-quality biosignals [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ]. Third, battery-powered wearable
devices used for monitoring have limited autonomy, especially in regions with unreliable
electricity, which restricts continuous operation [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ]. These challenges are particularly critical in
emergency scenarios, where delays or data loss can have life-threatening consequences.
      </p>
      <p>
        Traditional telemedicine systems rely on centralized architectures, where data is stored on a
single server, creating a single point of failure and increasing vulnerability to attacks. Static
compression methods such as Huffman coding or JPEG do not adapt to heterogeneous medical data
(biosignals, video, text) or variable network conditions, leading to increased latency and loss of
quality [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ]. Energy efficiency remains a concern, as wearable devices are expected to operate up to
24 hours without recharging in infrastructure-limited environments.
      </p>
      <p>
        Recent studies propose partial solutions to these challenges. Blockchain technology, particularly
Hyperledger Fabric, offers decentralized and tamper-resistant data storage, reducing the risk of
attacks [
        <xref ref-type="bibr" rid="ref9">9</xref>
        ]. Machine learning algorithms, such as convolutional neural networks (CNNs), are used
to optimize data processing and compression, adapting to both data types and network conditions
[
        <xref ref-type="bibr" rid="ref10">10</xref>
        ]. Low-power wide-area network (LPWAN) protocols like LoRa provide long-range
communication with minimal power consumption, making them suitable for remote regions.
However, integrated models that combine these technologies remain rare.
      </p>
      <p>This paper proposes a hybrid data transmission model that integrates:
1. A permissioned blockchain (Hyperledger Fabric) to ensure data security and integrity.
2. Adaptive CNN-based compression for dynamic bandwidth optimization depending on data
type and network conditions.
3. The LoRa protocol for energy-efficient communication in constrained environments.</p>
      <p>The novelty of this model lies in the holistic integration of these technologies to address the
unique challenges of telemedicine in low-resource settings. The model was evaluated through
simulations in MATLAB and NS-3, demonstrating substantial improvements in latency, energy
consumption, data security, and cost efficiency. The results suggest a scalable solution for
nextgeneration telemedicine systems capable of supporting global health initiatives, especially in
regions with weak infrastructure.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Literature review</title>
      <sec id="sec-2-1">
        <title>2.1. Data Transmission in Telemedicine</title>
        <p>
          Telemedicine systems handle diverse data types, such as biosignals (e.g., ECG, EEG), video streams
for remote consultations, and textual reports, each with specific demands for bandwidth, latency,
and quality. Traditional compression methods like JPEG for images and H.264 for video are widely
used but struggle to adapt to fluctuating network conditions, especially in rural areas with
bandwidth below 20 kbps [
          <xref ref-type="bibr" rid="ref11">11</xref>
          ]. Aguiar et al reviewed blockchain-based strategies for healthcare,
including secure medical data compression and sharing, but these approaches often do not address
data heterogeneity or real-time telemedicine needs [
          <xref ref-type="bibr" rid="ref12">12</xref>
          ]. Wavelet transforms have been shown to
effectively compress biosignals, achieving 30–50% data reduction without significant loss of
diagnostic quality, yet they lack adaptiveness for dynamic networks [13, 14]. Recent studies
indicate that dynamic compression can reduce latency in IoT systems, but these solutions often
overlook integration with blockchain or energy-efficient protocols, as well as the specific
requirements of telemedicine, such as preserving ECG quality in remote regions [15, 16]. This
underscores the need for adaptive compression solutions that account for both data types and
network variability.
        </p>
      </sec>
      <sec id="sec-2-2">
        <title>2.2. Security in Telemedicine</title>
        <p>The sensitive nature of medical data makes security a primary concern in telemedicine. Centralized
systems are prone to cyberattacks, such as data tampering and ransomware, which threaten data
confidentiality and integrity [17]. Blockchain technology, particularly Hyperledger Fabric, offers
decentralized storage and validation mechanisms that significantly mitigate data breach risks [18].
However, some blockchain-based security models for medical data do not support real-time
transmission, which is critical for emergency care. Decentralized EMR networks have been
proposed for secure data storage, but they often lack energy-efficient protocols or compression,
limiting their use in rural settings [19]. Blockchain can reduce attack risks substantially, though its
effective use in telemedicine requires integration with complementary technologies [20]. Smart
contracts and consensus mechanisms have been highlighted as effective tools for automating
transaction validation, enhancing data transparency and security in telemedicine systems [21],
[22].</p>
      </sec>
      <sec id="sec-2-3">
        <title>2.3. Energy Efficiency and LPWAN</title>
        <p>Wearable devices and IoT sensors in telemedicine require energy-efficient communication
protocols to prolong battery life, particularly in regions with unreliable power supply [23]. The
LoRa protocol, part of the LPWAN family, supports long-range communication up to 15 km while
consuming significantly less energy than Wi-Fi [24]. LoRa has been shown to reduce energy usage
by up to 40% compared to Wi-Fi, making it suitable for rural clinics [25]. It is also well-suited for
low-resource environments, where alternatives like NB-IoT are costlier and have shorter ranges
[26]. LoRa networks can support up to 1,000 devices without significant performance degradation,
confirming their scalability for regional telemedicine system.</p>
      </sec>
      <sec id="sec-2-4">
        <title>2.4. Machine Learning in Telemedicine</title>
        <p>Convolutional neural networks (CNNs) are widely applied in medical image analysis, biosignal
processing, and outcome prediction [27]. CNNs have also been used for compressing multimedia
data, achieving up to 25% size reduction without quality loss, though they often lack adaptability
for heterogeneous telemedicine data like ECGs or video streams [28]. A key limitation of CNNs is
their high computational cost on low-power devices. Offloading CNN training to a central server
while performing inference locally can address this issue. Studies on CNN-based ECG processing
show promise but often do not integrate these models with blockchain or LoRa, limiting their
realworld telemedicine applicability [22, 29].</p>
      </sec>
      <sec id="sec-2-5">
        <title>2.5. Ethical Considerations</title>
        <p>Medical data processing in telemedicine must comply with ethical regulations like the General
Data Protection Regulation (GDPR) [18]. Data anonymization and transparency are critical for
building patient trust. Blockchain-based models enhance privacy protection but require
welldefined access protocols [21]. Smart contracts can manage data access permissions, ensuring
compliance with international standards while maintaining data anonymity during transmission.</p>
      </sec>
      <sec id="sec-2-6">
        <title>2.6. Research Gaps</title>
        <p>
          Previous studies have not provided a fully integrated solution combining blockchain, adaptive
compression, LoRa, and cost-efficiency for telemedicine [
          <xref ref-type="bibr" rid="ref12">12, 30, 19</xref>
          ]. They often overlook
constraints of low-resource environments, such as limited bandwidth and unreliable electricity
[23]. For instance, Aguiar et al. [
          <xref ref-type="bibr" rid="ref11">11</xref>
          ] reviewed blockchain strategies focusing on static compression,
while others addressed security without real-time transmission [30] or emphasized EMR storage
without considering energy efficiency or data compression [19]. Other works offer partial solutions
but neglect economic and ethical dimensions [
          <xref ref-type="bibr" rid="ref12">12, 31</xref>
          ]. This model addresses these gaps by
proposing a comprehensive solution for next-generation global telemedicine systems.
        </p>
      </sec>
    </sec>
    <sec id="sec-3">
      <title>3. Materials and Methods</title>
      <sec id="sec-3-1">
        <title>3.1. System Architecture</title>
        <p>The proposed model consists of three interconnected layers, as illustrated in Figure 1:
1. Blockchain layer: Hyperledger Fabric is used for decentralized storage of medical data
hashes, validated by five trusted nodes (e.g., hospitals and clinics), ensuring data integrity
and transaction traceability [18].
2. Adaptive compression module: a convolutional neural network (CNN) dynamically adjusts
the compression ratio (CR) based on the type of data (ECG, video, text), network bandwidth
(10–100 kbps), and device energy level (0–100%), optimizing transmission efficiency [27].
3. Communication layer: The LoRa protocol enables energy-efficient long-range
communication (10–15 km) at speeds ranging from 0.3 to 50 kbps, making it ideal for
lowresource environments [23].</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Adaptive compression algorithm</title>
        <p>The adaptive compression algorithm is based on a CNN that classifies input data and predicts the
optimal compression ratio (CR), defined as (see formula 1) [13]:</p>
        <p>Original data size
CR=</p>
        <p>Compressed data size
.</p>
        <sec id="sec-3-2-1">
          <title>Input parameters include:</title>
          <p>1. Data type: biosignals (e.g., ECG, EEG), multimedia (e.g., video), text.
2. Network bandwidth: measured in real-time (10–100 kbps).
3. Device energy level: estimated using battery APIs (0–100%).</p>
          <p>A dedicated algorithm was developed to perform adaptive compression and data transmission,
dynamically adjusting the CR according to network conditions to ensure efficient LoRa-based
communication.</p>
          <p>The flowchart of the algorithm is presented in Figure 2.</p>
          <p>Dataset description:
1. ECG: 10,000 samples from the MIT-BIH Arrhythmia Database, sampled at 500 Hz,
preprocessed using wavelet filters for noise reduction [32].
2. Video: 5,000 video streams from the UCF-101 dataset, 720p at 30 fps, downsampled to 480p
for low-bandwidth conditions [33].
3. Text: 2,000 clinical reports from MIMIC-III, average size of 100 KB, metadata removed for
anonymization [34].
4. Preprocessing steps included amplitude normalization (ECG), video scaling, and text
cleaning.</p>
          <p>CNN architecture: 3 convolutional layers (32, 64, 128 filters, 3×3 kernels), 2 pooling layers (2×2),
2 fully connected layers (512 and 1 neuron), ReLU activation, Adam optimizer, Loss function: MSE.</p>
          <p>The model was trained on a GPU-based server (NVIDIA RTX 3080) for 50 epochs and achieved
95% prediction accuracy for compression ratio selection [28].</p>
        </sec>
      </sec>
      <sec id="sec-3-3">
        <title>3.3. Blockchain Implementation</title>
        <p>The blockchain layer is implemented using Hyperledger Fabric, a permissioned platform composed
of five nodes representing medical institutions (e.g., two central hospitals and three clinics). Each
data packet is hashed using SHA-256 and recorded as a blockchain transaction. Smart contracts
automate validation and grant access only to authorized users (e.g., doctors, administrators). The
test network processed up to 500 transactions per second, with an average validation time of 0.1
seconds. Node failure simulations demonstrated resilience in 95% of cases [18].</p>
      </sec>
      <sec id="sec-3-4">
        <title>3.4. Simulation Setup</title>
        <p>Simulations were conducted using MATLAB (signal processing) and NS-3 (network modeling) [35]:
Data types:</p>
        <sec id="sec-3-4-1">
          <title>1. Single-lead ECG: 60 KB/min, 500 Hz. 2. Video: 2 MB/min, 480p, 15 fps. 3. Text: 100 KB/min.</title>
        </sec>
        <sec id="sec-3-4-2">
          <title>Network:</title>
        </sec>
        <sec id="sec-3-4-3">
          <title>1. LoRa bandwidth: 10–100 kbps. 2. Transmission range: up to 10 km. 3. Spread factors: SF = 7–12. 4. Frequency: 868 MHz (European band).</title>
        </sec>
        <sec id="sec-3-4-4">
          <title>Device specifications:</title>
        </sec>
        <sec id="sec-3-4-5">
          <title>1. Wearable sensor. 2. 1000 mAh battery, 3.3 V. 3. ARM Cortex-M4 microcontroller.</title>
        </sec>
        <sec id="sec-3-4-6">
          <title>Blockchain:</title>
        </sec>
        <sec id="sec-3-4-7">
          <title>1. Hyperledger Fabric with 5 nodes. 2. 500 transactions/sec. 3. SHA-256 hashing.</title>
        </sec>
        <sec id="sec-3-4-8">
          <title>Baseline comparisons were conducted against:</title>
          <p>1. Static compression: Huffman coding (CR = 2).
2. Centralized security: no blockchain, data stored on a single server.
3. Wi-Fi transmission: IEEE 802.11n, 2.4 GHz.</p>
          <p>Performance metrics: transmission delay, energy consumption, security.</p>
        </sec>
      </sec>
      <sec id="sec-3-5">
        <title>3.5. Ethical considerations</title>
        <p>The model complies with the General Data Protection Regulation (GDPR) [36]. All data is
anonymized before processing, and access is controlled via smart contracts. Patients receive
explicit notifications regarding data usage, and their consent is securely stored on the blockchain.
Simulations used synthetic datasets to prevent potential privacy violations [37].</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Results</title>
      <sec id="sec-4-1">
        <title>4.1. Latency</title>
        <p>The proposed model reduced data transmission latency by 25% compared to static compression
(Huffman coding) and by 40% compared to uncompressed data transmission. At a bandwidth of 10
kbps, the model achieved a 96-second delay for transmitting 60 KB of single-lead ECG data,
compared to 128 seconds for Huffman coding and 160 seconds for uncompressed data [13].</p>
        <p>The CNN dynamically adjusted the compression ratio (CR), prioritizing biosignals (CR = 3) over
video streams (CR = 5) in low-bandwidth scenarios [28].</p>
        <p>Figure 3 presents a line graph illustrating latency (in seconds) for transmitting 60 KB of
singelead ECG data at bandwidths of 10, 50, and 100 kbps. Blue line: proposed model. Red line: Huffman.
Green line: uncompressed. The graph demonstrates a consistent 25% latency reduction at 10 kbps
for the proposed approach.</p>
      </sec>
      <sec id="sec-4-2">
        <title>4.2. Energy Consumption</title>
        <p>The proposed system achieved a 30% reduction in energy consumption compared to uncompressed
transmission and a 20% reduction compared to Wi-Fi.</p>
        <p>LoRa consumed only 100 mJ per transmission cycle, compared to 120 mJ for Wi-Fi and 140 mJ
for uncompressed data, extending battery life by approximately several hours using a 1000 mAh
battery in simulation [23].</p>
        <p>Computational overhead from CNN inference was minimized by offloading model training to a
centralized GPU server [14].</p>
        <p>Figure 4 presents a bar chart comparing energy consumption per cycle (in millijoules). Blue:
proposed model. Red: Wi- Fi. Green: uncompressed data. The proposed method shows the lowest
power consumption.</p>
      </sec>
      <sec id="sec-4-3">
        <title>4.3. Security</title>
        <p>The blockchain layer successfully detected and prevented 100% of simulated cyberattacks,
including man-in-the-middle attacks and data tampering. In contrast, the centralized architecture
was vulnerable to 80% of attacks. The SHA-256 hashing algorithm ensured data integrity with an
average verification time of 0.1 seconds per transaction [18].</p>
      </sec>
      <sec id="sec-4-4">
        <title>4.4. Bandwidth Sensitivity</title>
        <p>The system was tested under various bandwidth conditions (5–150 kbps). At 5 kbps, latency was:
180 seconds for single-lead ECG, 300 seconds for video, 120 seconds for text.</p>
        <p>This confirms the model's adaptive adjustment of the compression ratio (CR) to match real-time
network conditions. Compared to Huffman coding, the model retained performance advantages
even under extreme bandwidth constraints [28].</p>
        <p>Figure 5 shows a line graph of latency (seconds) across bandwidths from 5 to 150 kbps. Blue:
ECG, red: video, green: text.</p>
        <p>The proposed model outperformed static compression in all scenarios.</p>
      </sec>
      <sec id="sec-4-5">
        <title>4.5. Scalability</title>
        <p>The model was tested with network sizes ranging from 10 to 1,000 devices.</p>
        <p>Latency increased linearly (from 96 seconds to 144 seconds) as the number of devices grew, but
remained lower than that of Huffman-based systems (176 seconds at 1,000 devices).</p>
        <p>The blockchain layer sustained 500 transactions per second without failure, making it suitable
for regional telemedicine systems. Additional LoRa gateways ensured network stability at scales
exceeding 500 devices [23].</p>
        <p>The following Table 1 provides a concise summary of the simulation outcomes across key
performance metrics.</p>
        <sec id="sec-4-5-1">
          <title>Proposed Model</title>
        </sec>
        <sec id="sec-4-5-2">
          <title>Static Compression</title>
        </sec>
        <sec id="sec-4-5-3">
          <title>Uncompressed Wi-Fi</title>
        </sec>
        <sec id="sec-4-5-4">
          <title>Method</title>
        </sec>
        <sec id="sec-4-5-5">
          <title>Latency, s (at 10 kbps)</title>
        </sec>
        <sec id="sec-4-5-6">
          <title>Energy (mJ/60 KB) Security (%) 96 128</title>
          <p>160</p>
        </sec>
      </sec>
    </sec>
    <sec id="sec-5">
      <title>5. Discussion</title>
      <p>The proposed hybrid model demonstrates significant advantages over traditional telemedicine
architectures by integrating blockchain, adaptive compression, and energy-efficient communication
technologies. The inclusion of a permissioned blockchain ensures robust data security, addressing
vulnerabilities typical of centralized systems. Simulation results confirmed 100% resilience to
cyberattacks, supporting findings by Androulaki et al [18].</p>
      <p>
        The adaptive CNN-based compression algorithm outperforms static methods by dynamically
adjusting the compression ratio (CR) based on data type and real-time network conditions. This
flexibility is especially critical for heterogeneous telemedicine data, such as ECG signals, video
consultations, and clinical text, commonly transmitted over low-bandwidth rural networks [
        <xref ref-type="bibr" rid="ref11">11</xref>
        ].
The model achieved a 25% reduction in transmission latency and 30% lower energy consumption,
which is vital for real-time applications and battery-constrained wearable devices.
      </p>
      <p>
        Compared to prior research, the model exhibits unique strengths:
1. Unlike Aguiar et al. [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ], which focused on static blockchain-based data sharing, our
approach adapts to fluctuating bandwidth, improving efficiency under constrained
conditions.
2. In contrast to Kuo et al. [30], which lacked support for real-time transmission, the proposed
system ensures real-time data delivery, essential for emergency contexts such as stroke care
in remote areas [16].
3. Unlike Peng Zhang et al. [19], which emphasized secure EMR storage, our model
incorporates LoRa-based communication, improving energy efficiency and scalability for
remote healthcare systems.
      </p>
      <p>
        In addition, the model integrates economic and ethical aspects, often neglected in earlier studies
[31]. In low-resource regions, the ability to transmit a 60 KB ECG file in 96 seconds at 10 kbps,
compared to 160 seconds without compression, could be critical in life-saving scenarios [
        <xref ref-type="bibr" rid="ref12">12</xref>
        ].
      </p>
      <p>From a cost-efficiency perspective, the model is more economical than Wi-Fi and centralized
solutions due to the use of LoRa, which requires less expensive infrastructure and lower energy
consumption. Furthermore, unlike costlier alternatives such as 5G or NB-IoT (limited range), LoRa
offers a scalable solution for rural environments [26].</p>
      <p>The model also complies with ethical and legal requirements, such as GDPR, by integrating data
anonymization and smart contract-based access control. These features promote patient trust and
data transparency, aligning with recommendations by Gordon et al. [21].</p>
      <p>Despite its benefits, the proposed model has certain limitations:
1. High computational load from CNN inference on low-power devices, partially mitigated
through centralized training but requiring stable server access [14].
2. Limited bandwidth of LoRa (up to 50 kbps), which may affect high-resolution video
transmission, although this is compensated by adaptive compression [23].
3. Dependence on central infrastructure (for CNN and blockchain), which necessitates a stable
power supply at core network nodes – a challenge in remote regions [18].</p>
      <p>Future Work: The following research directions are recommended:
1. Integration of 5G in urban settings combined with LoRa for hybrid long-short range
networks.
2. Optimization of CNN for ultra-low power inference using quantized neural networks to
reduce processing load on wearables [15].
3. Pilot testing in real-world environments to evaluate long-term performance.
4. Development of hybrid LoRa + 5G architectures capable of supporting up to 5,000 devices.</p>
      <p>Additionally, recent developments in compact optical transmission, such as the use of
verticalcavity surface-emitting lasers (VCSELs), may further enhance telemedicine systems due to their
high-frequency modulation capabilities and low power consumption [38].</p>
      <p>Practical Implications: The proposed model can be deployed in regional health networks, support
emergency telemedicine during natural disasters (e.g., floods), and be integrated into global EMR
systems to enable centralized access to patient data [39]. The architecture can also be adapted to
local environmental conditions, such as deploying corrosion-resistant LoRa hardware in humid
climates.</p>
    </sec>
    <sec id="sec-6">
      <title>6. Conclusions</title>
      <p>The scientific novelty of the proposed model lies in the integrated application of three advanced
technologies – permissioned blockchain (Hyperledger Fabric), adaptive compression based on a
convolutional neural network (CNN), and the LoRa communication protocol – to enable secure,
energy-efficient, and scalable transmission of heterogeneous medical data in low-resource
environments.</p>
      <p>In contrast to existing approaches, the proposed model:
1. Dynamically adjusts the compression ratio based on data type, network bandwidth, and
battery level, optimizing performance under varying conditions.
2. Combines anonymized LoRa-based transmission with blockchain validation, ensuring data
confidentiality and integrity.
3. Achieves a 25% reduction in transmission latency and a 30% decrease in energy
consumption, while maintaining high compression accuracy and scalability up to 500
devices.
4. Offers a cost-effective solution compared to conventional telemedicine systems, making it
particularly attractive for developing countries.</p>
      <p>This work contributes a secure, efficient, and cost-effective solution for modern telemedicine,
particularly in underserved and infrastructure-poor regions. Potential applications include remote
monitoring of chronically ill patients, emergency telemedicine during disasters, and integration
with global electronic medical record (EMR) platforms.</p>
      <p>Policy Recommendations:
1. Integrate the proposed model into existing EMR systems to support rural hospitals in
developing countries.
2. Fund pilot projects in bandwidth-constrained regions.
3. Establish international standards for blockchain-based telemedicine systems that
incorporate both technical and ethical considerations.</p>
      <p>Future Research Directions:
1. Conduct real-world pilot studies in low-resource regions to evaluate the model’s long-term
effectiveness.
2. Integrate 5G for hybrid networking, combining urban high-speed access with LoRa’s
longrange capabilities.
3. Leverage AI-based medical prediction tools to enhance diagnostic accuracy based on
CNNprocessed data.
4. Optimize CNN models for ultra-low-power wearable devices using techniques such as
quantization and pruning.</p>
      <p>In summary, the proposed architecture offers a scalable and economically viable solution that
has the potential to transform global telemedicine, supporting the digital transformation of
healthcare in resource-constrained environments.</p>
    </sec>
    <sec id="sec-7">
      <title>Acknowledgements</title>
      <p>The author expresses sincere appreciation to Vinnytsia National Technical University and the
Department of Biomedical Engineering and Optoelectronic Systems for their continuous support,
academic guidance, and access to research facilities that contributed to the successful completion of
this study. The author also extends gratitude to colleagues for their valuable discussions and
constructive suggestions during the preparation of this work.</p>
    </sec>
    <sec id="sec-8">
      <title>Declaration on Generative AI</title>
      <p>During the preparation of this article, the author used ChatGPT to assist in improving the clarity
and structure of the text, as well as for language editing. All ideas, analyses, and conclusions
presented in the manuscript are the author’s own, and the author takes full responsibility for the
final content.
[13] S. Mallat, A wavelet tour of signal processing: The sparse way, 3rd. ed., Academic Press,</p>
      <p>Oxford, 2009.
[14] C. C. Aggarwal, Neural networks and deep learning, Springer, Cham, 2018.
[15] J. Li, M. S. Herdem, J. Nathwani, J. Z. Wen, Methods and applications for artificial intelligence,
big data, internet of things, and blockchain in smart energy management, Energy and AI 11
(2022). doi:10.1016/j.egyai.2022.100208.
[16] J. Petajajarvi, K. Mikhaylov, A. Roivainen, T. Hanninen, M. Pettissalo, On the coverage of
LPWANs: range evaluation and channel attenuation model for LoRa technology, in:
Proceedings of 14th International Conference on ITS Telecommunications, ITST ’2015, IEEE,
New York, NY, 2015, pp. 1–6. doi:10.1109/ITST.2015.7377400.
[17] C. S. Kruse, B. Frederick, T. Jacobson, D. K. Monticone, Cybersecurity in healthcare: A
systematic review of modern threats and trends, Technol. Health Care 25 (1) (2016).
doi:10.3233/THC-161263.
[18] E. Androulaki, A. Barger, V. Bortnikov, C. Cachin, et al., Hyperledger Fabric: a distributed
operating system for permissioned blockchains, in: Proceedings of the 13th EuroSys
Conference, EuroSys ’18, ACM, New Yor, USA, 2018. doi:10.1145/3190508.3190538.
[19] P. Zhang, J. White, D. Schmidt, FHIRChain: Applying blockchain to securely and scalably
share clinical data, Comput. Struct. Biotechnol. J. 16 (2018). doi:10.1016/j.csbj.2018.07.004.
[20] M. Mettler, Blockchain technology in healthcare: The revolution starts here, in: Proceedings of
the 18th IEEE International Conference on e-Health Networking, Applications and Services,
Healthcom ’16, IEEE, New York, NY, 2016, pp. 1–3. doi:10.1109/HealthCom.2016.7749510.
[21] W. J Gordon, C. Catalini, Blockchain technology for healthcare: Facilitating the transition to
patient-driven interoperability, Comput. Struct. Biotechnol. J. 16 (2018).
doi:10.1016/j.csbj.2018.06.003.
[22] I. Goodfellow, Y. Bengio, A. Courville, Deep learning, MIT Press, Cambridge, MA, 2016.
[23] A. Lavric, V. Popa, Performance evaluation of LoRaWAN communication scalability in
largescale wireless sensor networks, Wirel. Commun. Mob. Comput. 1 (2018).
doi:10.1155/2018/6730719.
[24] F. Adelantado, X. Vilajosana, P. Tuset-Peiro, B. Martinez, J. Melia-Segui, T. Watteyne,
Understanding the limits of LoRaWAN. IEEE Commun. Mag. 55 (9) (2017) 34–40.
doi:10.1109/MCOM.2017.1600613.
[25] K. Mekki, E. Bajic, F. Chaxel, F. Meyer, A comparative study of LPWAN technologies for
largescale IoT deployment, ICT Express 5 (1) (2019). doi:10.1016/j.icte.2017.12.005.
[26] M. Centenaro, C. E. Costa, F. Granelli, C. Sacchi, L. Vangelista, A Survey on technologies,
standards and open challenges in satellite IoT, IEEE Commun. Surv. Tutor. 23 (3) (2021).
doi:10.1109/COMST.2021.3078433.
[27] Y. LeCun, G. Hinton, Y. Bengio, Deep learning, Nature 521 (7553) (2015).</p>
      <p>doi:10.1038/nature14539.
[28] A. Esteva, B. Kuprel, R. A. Novoa, J. Ko, Dermatologist-level classification of skin cancer with
deep neural networks, Nature 542 (7639) (2017). doi:10.1038/nature21056.
[29] A. Krizhevsky, I. Sutskever, G. E. Hinton, ImageNet classification with deep convolutional
neural networks, Commun. ACM 60 (6) (2017) 84–90. doi:10.1145/3065386.
[30] T. Kuo, H. Kim, L. Ohno-Machado, Blockchain distributed ledger technologies for biomedical
and health care applications, J. Am. Med. Inform. Assoc. 24 (6) (2017).
doi:10.1093/jamia/ocx068.
[31] Q. Niu, H. Li, Y. Liu, Z. Qin, L. Zhang, J. Chen, Z. Lyu, Toward the internet of medical things:
architecture, trends and challenges, Math. Biosci. Eng. 21 (1) (2024) 650–678.
doi:10.3934/mbe.2024028.
[32] B. Moody, R. Mark, The impact of the MIT-BIH arrhythmia database, IEEE Eng. Med. Biol.</p>
      <p>Mag. 20 (3) (2001) 45–50. doi:10.1109/51.932724.
[33] K. Soomro, A. R. Zamir, M. Shah, UCF101: A Dataset of 101 Human Actions Classes From</p>
      <p>Videos in the Wild, arXiv preprint arXiv:1212.0402 (2012). doi:10.48550/arXiv.1212.0402.
[34] A. Johnson, T. Pollard, L. Lehman, MIMIC-III, a freely accessible critical care database,</p>
      <p>Scientific Data 3 (1) (2016). doi:10.1038/sdata.2016.35.
[35] A. Varga, R. Hornig, An overview of the OMNeT++ simulation environment, in: Proceedings of
the 1st International Conference on Simulation Tools and Techniques for Communications,
Networks and Systems &amp; Workshops, SIMUTools ’08, ICST, Marseille, France, 2008, pp. 1–10.
doi:10.4108/ICST.SIMUTOOLS2008.3027.
[36] European Union. General Data Protection Regulation (GDPR). Regulation (EU) 2016/679,</p>
      <p>Brussels, 2016. URL: https://eur-lex.europa.eu/eli/reg/2016/679/oj/eng.
[37] N. Kshetri, 1 Blockchain’s roles in meeting key supply chain management objectives, Int. J. Inf.</p>
      <p>Manage. 39 (2018) 80–89. doi:10.1016/j.ijinfomgt.2017.12.005.
[38] M. Alrawashdeh, H. Lysenko, S. Tuzhanskyi, et al., Modeling of operation regimes in
coupledcavity surface-emitting laser with external photon injection, in: Proceedings of 18th
Conference on Optical Fibers and Their Applications, Proceedings of SPIE, Bellingham, USA,
2019. doi:10.1117/12.2522107.
[39] World Health Organization, Telemedicine: Opportunities and developments in member states.</p>
      <p>WHO Global Observatory for eHealth, Geneva: WHO, 2010. URL:
https://iris.who.int/handle/10665/44497.</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          [1]
          <string-name>
            <given-names>Y.</given-names>
            <surname>Yaroslavskyy</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            <surname>Pavlov</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            <surname>Kostyuk</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            <surname>Tymchyk</surname>
          </string-name>
          ,
          <article-title>Principles of building telemedicine networks and systems based on fiber-optic communication channels in Vinnytsia region</article-title>
          ,
          <source>OEIPT</source>
          <volume>42</volume>
          (
          <issue>2</issue>
          ) (
          <year>2022</year>
          )
          <fpage>84</fpage>
          -
          <lpage>95</lpage>
          . doi:
          <volume>10</volume>
          .31649/
          <fpage>1681</fpage>
          -7893-2021-42-2-
          <fpage>84</fpage>
          -95.
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          [2]
          <string-name>
            <given-names>V. C.</given-names>
            <surname>Ezeamii</surname>
          </string-name>
          ,
          <string-name>
            <given-names>O. E.</given-names>
            <surname>Okobi</surname>
          </string-name>
          ,
          <string-name>
            <given-names>H.</given-names>
            <surname>Wambai-Sani</surname>
          </string-name>
          , et al.,
          <article-title>Revolutionizing healthcare: how telemedicine is improving patient outcomes and expanding access to care</article-title>
          ,
          <source>Cureus</source>
          <volume>16</volume>
          (
          <issue>7</issue>
          ) (
          <year>2024</year>
          ). doi:
          <volume>10</volume>
          .7759/cureus.63881.
        </mixed-citation>
      </ref>
      <ref id="ref3">
        <mixed-citation>
          [3]
          <string-name>
            <given-names>Y.</given-names>
            <surname>Ma</surname>
          </string-name>
          ,
          <string-name>
            <given-names>C.</given-names>
            <surname>Zhao</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Y.</given-names>
            <surname>Zhao</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            <surname>Lu</surname>
          </string-name>
          ,
          <string-name>
            <given-names>H.</given-names>
            <surname>Jiang</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Y.</given-names>
            <surname>Cao</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Y.</given-names>
            <surname>Xu</surname>
          </string-name>
          ,
          <article-title>Telemedicine application in patients with chronic disease: a systematic review and meta-analysis</article-title>
          ,
          <source>BMC Med</source>
          . Inform. Decis. Mak.
          <volume>22</volume>
          (
          <issue>105</issue>
          ) (
          <year>2022</year>
          ). doi:
          <volume>10</volume>
          .1186/s12911-022-01845-2.
        </mixed-citation>
      </ref>
      <ref id="ref4">
        <mixed-citation>
          [4]
          <string-name>
            <given-names>P.</given-names>
            <surname>Yakovyshen</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            <surname>Tuzhansky</surname>
          </string-name>
          ,
          <article-title>Analysis of data transmission methods in telemedicine systems</article-title>
          ,
          <source>OEIPT</source>
          <volume>1</volume>
          (
          <issue>47</issue>
          ) (
          <year>2024</year>
          )
          <fpage>222</fpage>
          -
          <lpage>232</lpage>
          . doi:
          <volume>10</volume>
          .31649/
          <fpage>1681</fpage>
          -7893-2024-47-1-
          <fpage>222</fpage>
          -232.
        </mixed-citation>
      </ref>
      <ref id="ref5">
        <mixed-citation>
          [5]
          <string-name>
            <given-names>P.</given-names>
            <surname>Ewoh</surname>
          </string-name>
          , T. Vartiainen,
          <article-title>Vulnerability to cyberattacks and sociotechnical solutions for health care systems: systematic review</article-title>
          ,
          <source>J. Med. Internet. Res</source>
          .
          <volume>26</volume>
          (
          <year>2024</year>
          ). doi:
          <volume>10</volume>
          .2196/46904.
        </mixed-citation>
      </ref>
      <ref id="ref6">
        <mixed-citation>
          [6]
          <string-name>
            <given-names>J.</given-names>
            <surname>Lai</surname>
          </string-name>
          ,
          <string-name>
            <given-names>N. O.</given-names>
            <surname>Widmar</surname>
          </string-name>
          ,
          <article-title>Revisiting the digital divide in the COVID‐19 era</article-title>
          .
          <source>Appl. Econ. Perspect. Policy</source>
          <volume>43</volume>
          (
          <issue>1</issue>
          ) (
          <year>2021</year>
          ). doi:
          <volume>10</volume>
          .1002/aepp.13104.
        </mixed-citation>
      </ref>
      <ref id="ref7">
        <mixed-citation>
          [7]
          <string-name>
            <given-names>C.</given-names>
            <surname>Xu</surname>
          </string-name>
          ,
          <string-name>
            <given-names>Yu</given-names>
            <surname>Song</surname>
          </string-name>
          , M. Han,
          <string-name>
            <surname>Hai-</surname>
          </string-name>
          Xia-Zhang,
          <article-title>Portable and wearable self-powered systems based on emerging energy harvesting technology</article-title>
          .
          <source>Microsyst. Nanoeng</source>
          .
          <volume>7</volume>
          (
          <issue>1</issue>
          ) (
          <year>2021</year>
          ). doi:
          <volume>10</volume>
          .1038/s41378- 021-00248-z.
        </mixed-citation>
      </ref>
      <ref id="ref8">
        <mixed-citation>
          [8]
          <string-name>
            <given-names>U.</given-names>
            <surname>Jayasankar</surname>
          </string-name>
          ,
          <string-name>
            <given-names>V.</given-names>
            <surname>Thirumal</surname>
          </string-name>
          ,
          <string-name>
            <given-names>D.</given-names>
            <surname>Ponnurangam</surname>
          </string-name>
          ,
          <article-title>A survey on data compression techniques: from the perspective of data quality, coding schemes, data type and applications</article-title>
          .
          <source>J. King Saud Univ. Comput. Inf. Sci</source>
          .
          <volume>33</volume>
          (
          <issue>2</issue>
          ) (
          <year>2021</year>
          ). doi:
          <volume>10</volume>
          .1016/j.jksuci.
          <year>2018</year>
          .
          <volume>05</volume>
          .006.
        </mixed-citation>
      </ref>
      <ref id="ref9">
        <mixed-citation>
          [9]
          <string-name>
            <given-names>M.</given-names>
            <surname>Hasnain</surname>
          </string-name>
          ,
          <string-name>
            <given-names>F. R.</given-names>
            <surname>Albogamy</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S. S.</given-names>
            <surname>Alamri</surname>
          </string-name>
          ,
          <string-name>
            <given-names>I.</given-names>
            <surname>Ghani</surname>
          </string-name>
          ,
          <string-name>
            <given-names>B.</given-names>
            <surname>Mehboob</surname>
          </string-name>
          ,
          <article-title>The hyperledger fabric as a blockchain framework preserves the security of electronic health records</article-title>
          ,
          <source>Front. Public Health</source>
          <volume>11</volume>
          (
          <year>2023</year>
          ). doi:
          <volume>10</volume>
          .3389/fpubh.
          <year>2023</year>
          .
          <volume>1272787</volume>
          .
        </mixed-citation>
      </ref>
      <ref id="ref10">
        <mixed-citation>
          [10]
          <string-name>
            <given-names>Y.</given-names>
            <surname>Zhou</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            <surname>Sollmann</surname>
          </string-name>
          ,
          <string-name>
            <given-names>J.</given-names>
            <surname>Chen</surname>
          </string-name>
          ,
          <article-title>Deep learning based image compression for microscopy images: an empirical study</article-title>
          ,
          <source>Biol. Imaging</source>
          <volume>4</volume>
          (
          <year>2024</year>
          ). doi:
          <volume>10</volume>
          .1017/S2633903X24000151.
        </mixed-citation>
      </ref>
      <ref id="ref11">
        <mixed-citation>
          [11]
          <string-name>
            <given-names>A.</given-names>
            <surname>Al-Fuqaha</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Guizani</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Mohammad</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Aledhari</surname>
          </string-name>
          ,
          <string-name>
            <given-names>M.</given-names>
            <surname>Ayyash</surname>
          </string-name>
          ,
          <article-title>Internet of things: a survey on enabling technologies, protocols, and applications</article-title>
          ,
          <source>IEEE Commun. Surv. Tutor</source>
          .
          <volume>17</volume>
          (
          <issue>4</issue>
          ) (
          <year>2015</year>
          )
          <fpage>2347</fpage>
          -
          <lpage>2376</lpage>
          . doi:
          <volume>10</volume>
          .1109/COMST.
          <year>2015</year>
          .
          <volume>2444095</volume>
          .
        </mixed-citation>
      </ref>
      <ref id="ref12">
        <mixed-citation>
          [12]
          <string-name>
            <surname>E. J. De Aguiar</surname>
            ,
            <given-names>B. S.</given-names>
          </string-name>
          <string-name>
            <surname>Faiçal</surname>
            ,
            <given-names>B.</given-names>
          </string-name>
          <string-name>
            <surname>Krishnamachari</surname>
          </string-name>
          ,
          <article-title>A survey of blockchain-based strategies for healthcare</article-title>
          ,
          <source>ACM Comput. Surv</source>
          .
          <volume>53</volume>
          (
          <issue>2</issue>
          ) (
          <year>2020</year>
          ). doi:
          <volume>10</volume>
          .1145/3376915.
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>