<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Archiving and Interchange DTD v1.0 20120330//EN" "JATS-archivearticle1.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Information Retrieval Journal 25 (2022) 239-268. URL: https://doi.org/10.1007/s10791</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.1007/S11192-023-04681-X</article-id>
      <title-group>
        <article-title>Science maps created exclusively with section-specific citations: Which topics emerge?</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Juan Pablo Bascur</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Suzan Verberne</string-name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>Centre for Science and Technology Studies, Leiden University</institution>
          ,
          <country country="NL">The Netherlands</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>Leiden Institute of Advanced Computer Science, Leiden University</institution>
          ,
          <country country="NL">The Netherlands</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2026</year>
      </pub-date>
      <volume>1</volume>
      <fpage>1181</fpage>
      <lpage>1199</lpage>
      <abstract>
        <p>Traditional science maps represent research topics by clustering documents, yet this process systematically favors some kinds of topics over others. If such topical emphasis could be influenced in a controlled way, science maps could be adapted to better support diferent use cases. In this paper, we investigate whether section-specific citation networks, derived from the Introduction, Methods, Results, or Discussion sections, can be used to improve the clustering efectiveness of certain topics relative to others. We evaluate diferences in clustering efectiveness between section-specific networks and a section-agnostic baseline network for topics belonging to 122 MeSHbased topic categories. Our largest network contains 7,507,751 documents and 36,286,575 citations. The results show that section-specific networks exhibit lower clustering efectiveness than the generic network for almost all topic categories, and that this reduced performance is likely related to the smaller number of citations rather than to intrinsic properties of section-specific citations. At the same time, we observe that diferent sections emphasize diferent kinds of topics, like social sciences in the Introduction, anatomy and medical techniques in the Discussion, and chemical substances in the Results. These findings indicate that while section-specific citation networks can shift topical salience in science maps, they are more efective as a complementary signal than as a standalone basis for map construction.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>1. Introduction</title>
      <p>
        Science maps are visualization techniques intended to represent the thematic organization of a collection
of academic documents. They are typically used for literature analysis [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ], field delimitation, research
policy, and enhanced document browsing [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ]. Typical practice for creating science maps is first to create
a network of academic documents where the links reflect shared characteristics such as bibliographic
metadata, then to cluster together the documents that are well connected, and finally to summarize the
contents of these clusters.
      </p>
      <p>In an ideal science map, each cluster would represent a single academic topic, and every document
from each topic would be assigned to its corresponding cluster. In clustering evaluation, the extent to
which a clustering solution (i.e. the set of clusters) approaches an underlying ground truth is called
clustering efectiveness [ 3]. A perfect clustering efectiveness can never be achieved in real science maps
because documents have multiple topics. In our previous work [4], we evaluated citation-based and
textsimilarity-based science maps for the biomedical domain, and found that there is a systematic diference
between the clustering efectiveness of topics depending on the category of topic. For example, topics
related to organisms or diseases have the highest efectiveness, while topics related to geographical
locations have the lowest. In a later work [5], we found that basing the science maps on other kinds
of attributes, beyond citation and text similarity, increases or decreases the clustering efectiveness of
diferent kinds of topics. For example, we found that a science map based on co-authorship has much
higher clustering efectiveness for topics related to geographical locations, relative to one based on text
similarity, while at the same time also having a lower clustering efectiveness for the other kinds of
topics that we evaluated.</p>
      <p>In the current paper, we continue this line of research, but this time with maps created exclusively
with citations that come from a given section of the academic document, be it Introduction, Methods,
results, or Discussion. This kind of analysis has become recently possible at a large scale due to
Clarivate systematically providing this information in the Web of Science [6]. We specifically address
the following research question: For which topic categories does the clustering efectiveness increase or
decrease when we create a science map using only the citations that come from a given section, compared
with a science map that uses all the citations?</p>
      <p>Our contributions are the following:
• We present the first large-scale, systematic evaluation of science maps constructed exclusively
from citations originating in a single document section (Introduction, Methods, Results, or
Discussion), and compare their clustering efectiveness with that of section-agnostic citation
maps across a wide range of topics.
• We conduct this evaluation across 122 MeSH-based topic categories and multiple network
constructions with up to 7 million documents and 36 million citations, evaluated across 140 clustering
resolutions and three coverage levels, allowing us to draw robust, category-level conclusions that
are representative of multiple clustering granularities.
• We show that, despite their lower overall efectiveness, diferent section-specific citation networks
emphasize diferent kinds of topics, suggesting that section-specific citations can function as a
complementary signal for influencing topic emergence in science maps.</p>
    </sec>
    <sec id="sec-2">
      <title>2. Related work</title>
      <p>The scientific field of citation context analysis studies how and why citations are used within academic
documents, including how citation behavior difers across sections. Prior work in this field has shown
that citation usage varies systematically between sections, suggesting that citations appearing in
diferent parts of a document serve diferent roles. This motivates our expectation that science maps
constructed from citations restricted to specific sections may improve the clustering efectiveness of
particular kinds of topics. At the same time, it is important to note that citation behavior is not stable
over time [7, 8] and that substantial diferences exist across disciplines [9, 8].</p>
      <p>Prior literature provides evidence for the following section-specific citation characteristics:
• Introduction section: Citations in the Introduction account for the largest share of in-text
citations within a document [10] and disproportionately reference older, highly cited, and seminal
works [11]. These citations are commonly used to position a study within an established body of
literature.
• Methods section: Citations in the Methods section are, on average, older [12] and highly
concentrated on a relatively small set of widely reused references [13]. Such citations tend to
recur across documents whenever a given method, protocol, or tool is employed.
• Results section: Citations in the Results section are often used for direct empirical comparison
with closely related studies.
• Discussion section: This section generally contains the fewest [10] and youngest [8] citations.</p>
      <p>These citations are frequently used to interpret findings and to relate the current work to broader
themes or bodies of literature.</p>
      <p>Several studies have also examined the efects of counting citations diferently depending on the
section in which they appear. On one hand, Thelwall [9] and Jeon and Jung [14] show that section-wise
citation counting can lead to substantially diferent ranking outcomes. On the other hand, Donner et
al. [15] find that such section-based citation counts, regardless of which section is considered, are not
correlated with peer assessments of the cited document’s quality. Taken together, these results indicate
that while section-wise citation counting produces substantial diferences in evaluation outcomes, these
diferences are not aligned with perceived academic quality.</p>
      <p>Section-wise citation information has also been incorporated into machine learning models. It has
also been used in citation recommendation systems, where recommendations are conditioned on the
section in which a citation is to be placed [16, 17]. Liang et al. [18] train a language model for science
mapping using citations weighted according to their section of origin. Their results show that excluding
citations from individual sections leads to only small changes in overall map quality, although the
highest performance is achieved by excluding citations from the Methods section. Their work is the
most closely related to our own; however, the underlying goal difers. Whereas Liang et al. aim to
optimize overall mapping quality through section weighting, our goal is to understand how restricting
citations to a single section afects the clustering efectiveness of diferent kinds of topics, under the
assumption that topics may be structurally incompatible.</p>
    </sec>
    <sec id="sec-3">
      <title>3. Methods</title>
      <sec id="sec-3-1">
        <title>3.1. Source of the networks</title>
        <p>Our citation networks are built as extended direct citation networks [19]. These are direct citation
networks with two types of documents: core documents, which are included in the science map, and
non-core documents, which are excluded from the science map but are used during clustering. This
approach allows the clustering to take into account that two documents can be connected through a
third document, even if that third document is not part of the science map itself. This is particularly
relevant for citation networks that are subsets of the global citation network (i.e., all documents within
a given time period), which is the case for the networks we construct here.</p>
        <p>Extended citation networks are created as follows. The network is undirected. For each core document,
we add all non-core documents that are connected to at least two core documents. Edge weights are
set to 1, node weights are set to 1 for core documents and 0 for non-core documents. The purpose of
the latter is so that in the clustering algorithm we use, the Leiden algorithm, the quality function of a
cluster is not reduced by adding non-core documents to that cluster.</p>
        <p>All documents and citations that we use in the networks originate from the same initial set of
documents and citations, defined as follows. We use the Web of Science (WoS) database from CWTS
(version 2025.39) and select all documents published in the years 2016, 2017, 2018, and 2019. This
publication window is chosen to allow documents to accumulate citations from documents published
after 2019. From this set, we further select only documents that have a PubMed ID, using the DOI as a
joining key and the PubMed database from CWTS (version 2025). This restriction is applied because, at
a later stage, we map properties of MeSH terms from PubMed onto the documents for topic evaluation.
Some WoS documents are associated with more than one PubMed ID; such documents are included
only once. We refer to this collection as the initial set of core documents.</p>
        <p>Using this initial set, we retrieve all WoS citations for which an initial core document appears either
as the citing or the cited document, and for which the section of the citation is known. These are the
only citations that we will use to construct the networks. If a document pair has citations in multiple
sections, we keep all section labels, and during network creation we treat these citations as a single
edge. Summary statistics of the initial data selection are reported in Table 1. WoS distinguishes four
categories for the section of origin of citations: Introduction, Methods, Results, and Discussion. WoS
does not publish the methodology used to disambiguate sections; however, in citation context analysis
it is common practice to assign Background to Introduction and Conclusion to Discussion [20].</p>
      </sec>
      <sec id="sec-3-2">
        <title>3.2. Construction of the networks</title>
        <p>For each section, we construct two networks: one containing only citations originating from that
section, which we call the Pure network, and one containing citations from any section, which we call
the Baseline network. The Baseline network serves as a reference to assess how using section-specific
citations difers from using all citations. The sizes of all networks are reported in Table 2.</p>
        <p>The construction of a Pure network proceeds as follows. We identify all initial citations belonging to
the given section. From this set, we remove the citations with non-core documents that connect to a
single core document. The remaining citations define the network, and the remaining core documents
constitute the section-specific core document set.</p>
        <p>To construct the Baseline network, we identify all initial citations that contain a section-specific
core document. From this set, we remove the citations with non-section-specific-core documents that
connect to a single section-specific core document. The remaining citations define the network, and
only section-specific core documents are considered core documents. This means that some initial core
documents can become non-core documents in this network. We do this so that the Pure and Baseline
networks have exactly the same core documents, so we can later compare their clustering efectiveness.</p>
      </sec>
      <sec id="sec-3-3">
        <title>3.3. Topics and topic categories</title>
        <p>Topics are concepts that describe the content of a document, and a document can have any number of
topics. Topic categories are a way of grouping topics together. For example, topics Dog and Cat belong
to the topic category Organisms. We use the same method as in our previous work [5] to define which
documents belong to which topics and to which topic categories these topics belong. In the current
subsection, we will make a high level summary of this method and go into detail on how the current
paper difers from this method.</p>
        <p>The MeSH terms, which is a controlled vocabulary thesaurus used for indexing PubMed, are used to
assign documents to topics and topics to topic categories. The MeSH tree is a structure that organizes
the MeSH terms into a hierarchical structure, where tree nodes are subtopics of their parent node.</p>
        <p>The topics in our work are the tree nodes of the MeSH tree. Assigning topics to a document works
the following way: The document already has MeSH terms assigned (obtained from the in-house CWTS
database of PubMed and MeSH version 2025). The MeSH terms are mapped to the MeSH tree, where
they are transformed into their tree node version (there can be more than one tree node per MeSH
term). Then, all the tree nodes that are ancestors of these tree nodes are also assigned to the document.
We refer to a topic or a topic category (see below) using its tree node identifier followed by its MeSH
term name (e.g., [A01.456] Head ) so to diferentiate between nodes of the same MeSH term.</p>
        <p>The topic categories are the branch and first level of the MeSH tree (i.e., the two highest levels).
All topics descendants of a given branch or first-level node are assigned to the corresponding topic
category. We exclude the following topic categories:
• The entire branch Publication Characteristics [V ], including its first level, because it contains no
documents.
• The categories Humanities [K01], Information Science [L01], Persons [M01], and Geographic
Locations [Z01], because each of these is the only first-level MeSH term in its branch, making it
operationally equivalent to the branch itself as a topic category.
In total, we obtained 122 topic categories.</p>
        <p>We filter out some topics and topic categories to improve our evaluation, and we do independent
ifltering per section because each section has diferent core documents. First, we remove the topics
that have a size (number of documents) outside a given range (see below for details), with the purpose
of saving computational resources. Then we filter by redundancy, that is when topics that share a
substantial number of documents (Jaccard similarity &gt;= 0.5). From a set of redundant topics, we keep
the one with the fewest documents and discard the rest. The final filter is topic category size, where we
remove topic categories with less than 10 topics.</p>
        <p>The size filtering range always has a minimum of 40 documents so to have meaningful topics.
However, if after the redundancy filtering we have less than 50 topics, then we increase the maximum
size and do the redundancy filtering again. We use the following maximum sizes: 250, 500, 100, 2000,
4000, 8000.</p>
      </sec>
      <sec id="sec-3-4">
        <title>3.4. Clustering</title>
        <p>We use the Leiden algorithm [21] for clustering, which is commonly applied in the construction of
science maps. The algorithm requires the user to specify a resolution parameter, which controls cluster
granularity, with higher resolution values leading to smaller clusters. For each network, we generate
140 clustering solutions using 140 diferent resolution values. The highest resolution is set to 10, and
each subsequent resolution value is obtained by multiplying the previous one by a factor of 7/8 (e.g.,
10, 8.75, 7.65625, . . . ).</p>
        <p>This geometric progression was chosen because it provides a smooth transition from clustering
solutions in which most nodes are isolated to solutions in which most nodes belong to a single cluster,
while keeping the total number of resolutions suficiently low to allow computation within a reasonable
time frame. In practice, clustering all networks for a single section takes approximately one day.</p>
        <p>All clustering is performed using the Python implementation of the Leiden algorithm provided by
the igraph library [22]. All clustering solutions generated across the diferent resolution values are
retained and used in the subsequent evaluation and comparison analyses.</p>
      </sec>
      <sec id="sec-3-5">
        <title>3.5. Evaluation</title>
        <p>Our evaluation framework follows the methodology introduced in our previous work [5]. In this section
we make a high level description of how we evaluate clustering efectiveness, and the formal definitions
and implementation details are provided in [5].</p>
        <p>The clustering efectiveness of a topic is assessed based on the clusters that contain topic documents.
Rather than selecting all such clusters, we select only enough clusters to jointly cover a given fraction
of the topic documents. We refer to this fraction as Coverage. All evaluations are replicated at Coverage
values of 0.25, 0.50, and 0.75.</p>
        <p>Clustering efectiveness at the topic level is characterized using two concepts:
• Number of selected clusters (NSC): The number of clusters required to achieve the specified</p>
        <p>Coverage value.</p>
        <p>• Purity: The fraction of documents in the selected clusters that belong to the topic.</p>
        <p>Each clustering solution, corresponding to a diferent Resolution value, generates its own Purity and
NSC for a given topic. To summarize clustering efectiveness across multiple clustering solutions, we
construct a Purity profile. A Purity profile represents, for a given topic, the highest Purity value achieved
at each NSC value across all clustering solutions, evaluated over a predefined set of NSC values (details
in our prior work [5]).</p>
        <p>To compare the clustering efectiveness of a topic between the Pure and Baseline networks, we
compare the corresponding topic Purity profiles by evaluating their Purity values at the same NSC
values. We say that one Purity profile is higher than another if its Purity values are higher for the
majority of NSC values.</p>
        <p>To identify which topic categories perform better in one network than the other, we count how many
of their topics had higher clustering efectiveness in one network than the other. We call this value
Purity Diference, we measure it as the fraction of total topics (i.e. takes value from 0 to 1), and it is one
of our key results to answer the research question. A Purity Diference greater than 0.5 indicates that
the majority of topics in the category have higher clustering efectiveness in the Pure network than
in the Baseline network, and is therefore interpreted as the Pure network outperforming the Baseline
network for that topic category.</p>
      </sec>
    </sec>
    <sec id="sec-4">
      <title>4. Results</title>
      <p>The average Purity Diferences per topic category is reported in Table 3, and summarized in Figure 1.
For each category, this value is the average of the Purity diferences for the three Coverage values.</p>
      <p>Across categories, Introduction consistently shows the highest values, followed by Discussion, Results,
and Methods. With the exception of two categories in Introduction, no category exceeds a value of 0.5,
which indicates that section-specific networks rarely outperform baseline clustering across most topics
in any category.</p>
      <p>Introduction exhibits elevated values across most categories, with values above 0.30 in the majority
of cases. Lower values are mostly observed in categories in the branches Anatomy, Analytical (...),
and Phenomena and Processes. Values above 0.35 are mostly observed for categories in the branches
Organisms, Psychiatry and Psychology, Disciplines and Occupations, Anthropology (...), Technology
(...), Information Science, Named Groups, Health Care, and Geographicals. It achieves values higher
than 0.50 on categories [G17] Mathematical Concepts and [H01] Natural Science Discipline.</p>
      <p>In Discussion, values are generally above 0.25 for categories in the branches Anatomy, Diseases,
Analytical (...), and Geographicals. In Results, above 0.15 for categories in the branches Organisms and
Chemicals and Drugs. In Methods, above 0.10 for categories in the branches Disciplines and Occupations,
Information Science, Health Care and Geographicals.</p>
    </sec>
    <sec id="sec-5">
      <title>5. Discussion</title>
      <p>While it is not surprising that only a small number of topic categories outperform the baseline, given
that the baseline networks contain more information, it is unexpected that this number is nearly zero.
From the perspective of clustering efectiveness, this suggests that there is no systematic advantage to
using section-specific citation networks over section-agnostic ones.</p>
      <p>We observe that the ordering of sections by Purity Diference matches the ordering by the ratio of
citations between the Pure and Baseline networks (Table 2). This ratio reflects the extent to which the
Baseline network contains more information than the corresponding Pure network, and suggests that
the lower clustering efectiveness of section-specific networks is primarily due to their smaller number
of citations. Under this interpretation, section-specific networks might outperform the baseline in some
topic categories if they were enriched with additional information. Evidence supporting this possibility
can be found in our prior work [5], where networks that combine multiple data sources outperform
those based on a single source for several topic categories.</p>
      <p>A straightforward way to enrich section-specific networks would be to include citations from all
sections while assigning higher weights to citations originating from a specific section. Under this
view, the networks used in our experiments can be interpreted as extreme cases: the Baseline network
assigns equal weight to all citations with known section origin, while the Pure section network assigns
zero weight to citations from other sections. Related approaches have been explored in prior work; for
example, Liang et al. [18] assign diferent weights to citations depending on their section of origin and
set the weight of Methods citations to zero. Identifying an optimal weighting scheme between
sectionspecific and non-section citations, however, is likely to pose a substantial computational challenge.</p>
      <p>An alternative explanation for the observed correlation with the citation ratio is that the lower
performance of section-specific networks is not solely due to reduced information volume, but rather
to their increased dissimilarity from the baseline network. Since all citations in the section-specific
networks are also present in the baseline network, the correlation may simply reflect how similar each
section-specific network is to the baseline.</p>
      <p>We also observe consistent diferences in which topic categories are most salient across sections.
Several branches of topic categories achieve relatively high values in only a single section, such as
Psychiatry and Psychology and Anthropology (...) in the Introduction, Anatomy and Analytical (...)
in the Discussion, and Chemicals and Drugs in the Results. This is precisely the type of behavior we
aimed to uncover: diferent sections can make diferent topics more salient in a science map.</p>
      <p>We can ofer plausible interpretations for why these branches exhibit elevated values in specific
sections. In the Results section, documents frequently compare empirical outcomes with prior studies
that employed similar experimental setups, which naturally leads to citations involving overlapping
chemical substances. In the Introduction section, the branches showing higher values are related to the
social sciences. This aligns with the role of the Introduction in biomedical articles in contextualizing
research relevance and societal impact. In the Discussion section, the branches showing higher values
are related to anatomy and medical techniques. This may reflect the role of this section in research on
medical treatments, where authors contrast their treatment with existing approaches, often requiring
more detailed reference to afected body parts and the equipment or techniques involved.</p>
      <p>Finally, we observe cases in which a topic category achieves high values while the other categories in
the branch perform poorly, such as Archaea [B02] in the Results section. This highlights the importance
of using a more granular system of topic categories, as such patterns would be obscured if analysis
were limited to the branch level.</p>
    </sec>
    <sec id="sec-6">
      <title>6. Conclusions</title>
      <p>We investigated whether restricting citation links to a single document section (Introduction, Methods,
Results, or Discussion) changes which topics emerge more cleanly in citation-based science maps.
Using large-scale Web of Science citation-section metadata and evaluating clustering efectiveness by
MeSH-based topic categories, we compared section-specific (Pure) networks against section-agnostic
(Baseline) networks that include citations from all sections.</p>
      <p>For nearly all topic categories, the majority of topics exhibit lower clustering efectiveness in
sectionspecific citation networks than in section-agnostic ones. Introduction-based maps exhibit the highest
performance across all categories, followed by Discussion, Results, and Methods. This ordering of
sections matches the ordering by the ratio of citations between the Pure and Baseline networks,
suggesting that the cause of the lower performance could be lack of information rather than the
sections.</p>
      <p>At the same time, the results show that diferent sections emphasize diferent kinds of topics. In
general terms, the kind of topics that were emphasized only in a single section were: Social sciences in
Introduction, parts of the body and medical techniques and equipment in Discussion, and chemical
substances in Results. These results indicate that there is a topical diference between science maps
derived from sections, although the low performance means that maps made exclusively of sections are
inferior in practical terms.</p>
      <p>Further research should focus on finding how to take advantage of the topical diferences between
sections such that high clustering efectiveness can be achieved for these topics. A simple research line
is to retain all citations while weighting them by section of origin. Such weighting can be interpreted
as interpolating between the two extremes we tested, with uniform weighting in the baseline versus
zeroing all but one section in the pure networks. Another research line is to complement section
information with the Citation Function Classes of Web of Science [6], which captures the intent of the
citation. A final research line is the use of language models optimized to be salient in certain topics.
These language models could be trained using only the citations from specific sections, similarly to the
work of Liang et al. [18].</p>
    </sec>
    <sec id="sec-7">
      <title>Declaration on Generative AI</title>
      <p>During the preparation of this work, the authors used ChatGPT, Claude in order to: Grammar and
spelling check, Paraphrase and reword, Improve writing style. After using this tool, the authors reviewed
and edited the content as needed and takes full responsibility for the publication’s content.
Topic Category I M R D
[A20] Bacterial Structures - - 0.10
[A21] Viral Structures - - -
[B] Organisms 0.45 0.07 0.18 0.19
[B01] Eukaryota 0.48 0.09 0.17 0.18
[B02] Archaea 0.37 0.09 0.38 0.21
[B03] Bacteria 0.40 0.02 0.19 0.21
[B04] Viruses 0.37 0.03 0.13 0.22
[B05] Organism Forms 0.20 0.09 0.12 0.17
[C] Diseases 0.31 0.04 0.09 0.29
[C01] Infections 0.31 0.02 0.07 0.29
[C04] Neoplasms 0.28 0.07 0.11 0.34
[C05] Musculoskeletal Diseases 0.29 0.05 0.14 0.26
[C06] Digestive System Diseases 0.30 0.07 0.16 0.29
[C07] Stomatognathic Diseases 0.30 0.04 0.07 0.31
[C08] Respiratory Tract Diseases 0.29 0.05 0.06 0.27
[C09] Otorhinolaryngologic Diseases 0.36 0.04 0.09 0.28
[C10] Nervous System Diseases 0.36 0.04 0.09 0.26
[C11] Eye Diseases 0.30 0.04 0.11 0.29
[C12] Urogenital Diseases 0.26 0.03 0.07 0.31
[C14] Cardiovascular Diseases 0.33 0.05 0.11 0.34
[C15] Hemic and Lymphatic Diseases 0.33 0.05 0.08 0.30
[C16] Congenital, Hereditary, and Neonatal Diseases and Abnormalities 0.36 0.04 0.09 0.24
[C17] Skin and Connective Tissue Diseases 0.30 0.04 0.08 0.29
[C18] Nutritional and Metabolic Diseases 0.35 0.03 0.05 0.24
[C19] Endocrine System Diseases 0.25 0.02 0.10 0.31
[C20] Immune System Diseases 0.37 0.06 0.07 0.33
[C21] Disorders of Environmental Origin - - -
[C22] Animal Diseases 0.34 0.02 0.09 0.21
[C23] Pathological Conditions, Signs and Symptoms 0.31 0.05 0.09 0.29
[C24] Occupational Diseases - - -
[C25] Chemically-Induced Disorders 0.29 0.01 0.07 0.22
[C26] Wounds and Injuries 0.27 0.03 0.09 0.31
[D] Chemicals and Drugs 0.34 0.10 0.27 0.27
[D01] Inorganic Chemicals 0.35 0.08 0.22 0.16
[D02] Organic Chemicals 0.43 0.10 0.28 0.23
[D03] Heterocyclic Compounds 0.40 0.10 0.23 0.26
[D04] Polycyclic Compounds 0.42 0.12 0.20 0.29
[D05] Macromolecular Substances 0.35 0.08 0.29 0.33
[D06] Hormones, Hormone Substitutes, and Hormone Antagonists 0.32 0.04 0.13 0.34
[D08] Enzymes and Coenzymes 0.30 0.10 0.30 0.27
[D09] Carbohydrates 0.31 0.12 0.29 0.24
[D10] Lipids 0.39 0.11 0.25 0.20
[D12] Amino Acids, Peptides, and Proteins 0.30 0.09 0.30 0.32
[D13] Nucleic Acids, Nucleotides, and Nucleosides 0.42 0.18 0.31 0.22
[D20] Complex Mixtures 0.38 0.04 0.15 0.21
[D23] Biological Factors 0.28 0.11 0.24 0.28
[D25] Biomedical and Dental Materials 0.24 0.05 0.07 0.19
[D26] Pharmaceutical Preparations 0.32 0.08 0.06 0.28
[D27] Chemical Actions and Uses 0.34 0.09 0.16 0.23
[E] Analytical, Diagnostic and Therapeutic Techniques, and Equipment 0.30 0.09 0.13 0.32
[E01] Diagnosis 0.30 0.11 0.13 0.32
[E02] Therapeutics 0.26 0.05 0.11 0.32
[E03] Anesthesia and Analgesia 0.10 0.02 0.02 0.19
[E04] Surgical Procedures, Operative 0.24 0.05 0.16 0.46
[E05] Investigative Techniques 0.36 0.16 0.15 0.22
Continued on next page
Topic Category
[E06] Dentistry
[E07] Equipment and Supplies
[F] Psychiatry and Psychology
[F01] Behavior and Behavior Mechanisms
[F02] Psychological Phenomena
[F03] Mental Disorders
[F04] Behavioral Disciplines and Activities
[G] Phenomena and Processes
[G01] Physical Phenomena
[G02] Chemical Phenomena
[G03] Metabolism
[G04] Cell Physiological Phenomena
[G05] Genetic Phenomena
[G06] Microbiological Phenomena
[G07] Physiological Phenomena
[G08] Reproductive and Urinary Physiological Phenomena
[G09] Circulatory and Respiratory Physiological Phenomena
[G10] Digestive System and Oral Physiological Phenomena
[G11] Musculoskeletal and Neural Physiological Phenomena
[G12] Immune System Phenomena
[G13] Integumentary System Physiological Phenomena
[G14] Ocular Physiological Phenomena
[G15] Plant Physiological Phenomena
[G16] Biological Phenomena
[G17] Mathematical Concepts
[H] Disciplines and Occupations
[H01] Natural Science Disciplines
[H02] Health Occupations
[I] Anthropology, Education, Sociology, and Social Phenomena
[I01] Social Sciences
[I02] Education
[I03] Human Activities
[J] Technology, Industry, and Agriculture
[J01] Technology, Industry, and Agriculture
[J02] Food and Beverages
[J03] Non-Medical Public and Private Facilities
[K] Humanities
[L] Information Science
[M] Named Groups
[N] Health Care
[N01] Population Characteristics
[N02] Health Care Facilities Workforce and Services
[N03] Health Care Economics and Organizations
[N04] Health Services Administration
[N05] Health Care Quality, Access, and Evaluation
[N06] Environment and Public Health
[Z] Geographicals
learning for large-scale science mapping, Information Processing &amp; Management 63 (2026)
104557. URL: https://www.sciencedirect.com/science/article/pii/S0306457325004984. doi:https:
//doi.org/10.1016/j.ipm.2025.104557.
[19] L. Waltman, K. W. Boyack, G. Colavizza, N. J. van Eck, A principled methodology for comparing
relatedness measures for clustering publications, Quantitative Science Studies 1 (2020) 691–713.
doi:10.1162/qss_a_00035.
[20] T.-K. Hsiao, V. I. Torvik, Opcitance: Citation contexts identified from the pubmed central open
access articles, Scientific Data 10 (2023) 243. doi:10.1038/s41597-023-02134-x.
[21] V. A. Traag, L. Waltman, N. J. Van Eck, From louvain to leiden: guaranteeing well-connected
communities, Scientific reports 9 (2019) 1–12. doi:10.1038/s41598-019-41695-z.
[22] G. Csardi, T. Nepusz, The igraph software package for complex network research, InterJournal,
Complex Systems 1695 (2006).</p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ref1">
        <mixed-citation>
          [1]
          <string-name>
            <given-names>M.</given-names>
            <surname>Zitt</surname>
          </string-name>
          ,
          <article-title>Meso-level retrieval: IR-bibliometrics interplay and hybrid citation-words methods in scientific fields delineation</article-title>
          ,
          <source>Scientometrics</source>
          <volume>102</volume>
          (
          <year>2015</year>
          )
          <fpage>2223</fpage>
          -
          <lpage>2245</lpage>
          . doi:
          <volume>10</volume>
          .1007/s11192-014-1482-5.
        </mixed-citation>
      </ref>
      <ref id="ref2">
        <mixed-citation>
          [2]
          <string-name>
            <given-names>J. P.</given-names>
            <surname>Bascur</surname>
          </string-name>
          ,
          <string-name>
            <given-names>S.</given-names>
            <surname>Verberne</surname>
          </string-name>
          ,
          <string-name>
            <surname>N. J. van Eck</surname>
          </string-name>
          ,
          <string-name>
            <given-names>L.</given-names>
            <surname>Waltman</surname>
          </string-name>
          , Academic information retrieval using citation
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>