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      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Oliver Kohlbacher</string-name>
          <email>oliver.kohlbacher@uni-tuebingen</email>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Jano I. van Hemert</string-name>
          <email>j.vanhemert@ed.ac.uk</email>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>University of Edinburgh, School of Informatics</institution>
          ,
          <addr-line>Informatics Forum, 10 Crichton Street, Edinburgh EH8 9AB</addr-line>
          ,
          <country country="UK">United Kingdom</country>
        </aff>
        <aff id="aff1">
          <label>1</label>
          <institution>University of T u ̈bingen, Wilhelm Schickard Institute, Departement for Simulation of Biological Systems</institution>
          ,
          <addr-line>Sand 14, 72070 T u ̈bingen</addr-line>
          ,
          <country country="DE">Germany</country>
        </aff>
      </contrib-group>
      <pub-date>
        <year>2009</year>
      </pub-date>
      <abstract>
        <p>The topic ”'Portals for Life Sciences”' includes various research fields, on the one hand many different topics out of life sciences, e.g. mass spectrometry, on the other hand portal technologies and different aspects of computer science, such as usability of user interfaces and security of systems. The main aspect about portals is to simplify the user's interaction with computational resources which are concerted to a supported application domain.</p>
      </abstract>
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      <title>INTRODUCTION</title>
      <p>Life sciences cover a broad range of different disciplines including
biology and medicine. In all these fields computational tools have
become indispensable in research and development. Computational
methods often require specific computational resources and highly
advanced computing skills for installation, administration, and daily
use. Scientists want to focus on their specific research combining all
kinds of approaches, but they do not want to deal with the details of
software installation, usability, and hardware configuration. Hence,
there is a need for self-explanatory and intuitive user interfaces for
computational tools in the life sciences.</p>
      <p>Currently, three important basic types of interfaces to applications
exist: desktop applications, portals, and script interfaces. The
installation of scientific software on the user side is often awkward and
difficult. It also requires users to take the responsibility of keeping
their software up-to-date. Portals offer an alternative interface that
avoids most of these drawbacks. In general, a portal can be defined
as a framework for integrating information, applications, and
processes across organisational boundaries and as a single entry point
for a community. Users are in the position to customise their tools
and views and are provided with a repository of personal
information. Most users are familiar to using portals such as Amazon or
Google.</p>
      <p>However, like every technology the use of portal frameworks has
advantages and disadvantages. The advantages are mostly on the
user’s side and the disadvantages are more on the developer’s and
administrator’s side. Users are not burdened by software rollouts,
firewall issues, and platform issues. Additionally, they are able to
access a portal from everywhere they have access to the Internet.
This advantage directly implies an important disadvantage of
portals: they rely on the availability of the portal server and a fast
Internet connection. Another disadvantage is that users are not able
to access local data in a portal unless the developer of a portlet offers
the possibility to upload data. Developers have to deal with portal
technology, which is often still in an early stage of development and
not as robust as other technologies. Since the advantages outweigh
the disadvantages, portals are an important state-of-the-art
technology to meet users’ needs.</p>
      <p>There are various aspects to consider in the context of portals. The
main aspect is the user in the supported domain and his role as
end-user, developer or administrator. Irrespective of the underlying
infrastructure and whether the integrated tools rely on internet
technologies, on grid computing or cloud computing, the user should
be empowered with intuitive tools. Besides the usability, the
monitoring of jobs is an important aspect. Monitoring enables users to
control the status of their jobs. The access to tools and data is
granted on the basis of an authentication and authorisation concept.
Especially, the access to data and large data set sizes is a sensitive
topic in the field of life sciences, which emphasises the important
role of security in portals and the need for a sophisticated
distributed data management.</p>
      <p>In the context of portals, there is still the need to simplify
humancomputer interaction. The kind of simplification that is chosen
depends on the specific domain the portal is developed for and
which elements of the researchers’ work the portal supports.
Accordingly, there are many different kinds of portals and the following
ones are only an extract: a portal that purely consists of a
collection of links; a workflow-enabled portal that offers the possibility to
orchestrate and submit workflows; a semantic portal that supports
the development of an ontology; a data portal that provides tools
for sophisticated data management. Even though these portals are
quite diverse from an user’s point of view, developers of portals can
base the involved technologies on similar concepts and
infrastructures. The exchange of experience, ideas and needs between users
and developers is highly beneficial for achieving technological and
functional advances on portals for life sciences.</p>
      <p>Speakers at IWPLS’09 discussed various kinds of portals with focus
on different aspects, tools, technologies, and application domains.
The nine papers accepted for oral presentation at IWPLS’09 are
collected in this volume. They were selected based on their quality and
suitability to the workshop.
Sandra Gesing1, Oliver Kohlbacher1 and Jano I. van Hemert2</p>
    </sec>
    <sec id="sec-2">
      <title>FUNDING</title>
      <p>We acknowledge the sponsorship of the e-Science Institute and the
Scottish Bioinformatics Forum to the 2009 International Workshop
on Portals for Life Sciences.</p>
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