Semantic Web Applications and Tools for Life Sciences SWAT4LS – 2009 SWAT4LS (Semantic Web Applications and Tools for Life Sciences) is a workshop that aims at providing a venue to critically discuss benefits and limits of Semantic Web technologies and tools in the Life Sciences. The second edition of SWAT4LS was held in Amsterdam Science Park on November 20 th 2009. The workshop was attended by nearly sixty people, with a worldwide attendance, and received in total twenty-seven submissions, out of which fifteen for full papers and twelve for posters and demos. The final programme consisted of three keynotes, six talks, three short talks selected from posters, five demos, about ten posters and a panel discussion. The keynotes were given by Alan Ruttenberg (Semantic Web Technology to Support Studying the Relation of HLA Structure Variation to Disease), Michael Schroeder (Prediction of drug-target interactions from literature by context similarity) and Barend Mons (CWA: The meta-analysed Semantic Web, getting rid of ambiguity and redundancy). Overall, the programme was balanced between applications, tools and perspective contributions. A review form was circulated at the end of the workshop. Feedback from participants showed a unanimously high appreciation of the workshop, and an almost equally unanimous request for tutorials and practical sessions. Overall, a lot of progress has been made in the application of Semantic Web to Life Sciences. While there are still concerns about scalability and performance, there is a consensus that the technology is now mature enough for practical applications. However, at the same time, a “killer application” that shows the potential of the Semantic Web in this area of science has yet to be unveiled. Perhaps, like the ubiquitous changes XML has brought about, the transformation will be subtle but nevertheless far reaching. The SWAT4LS organizers wish to thank the programme committee, the authors and all participants for their contributions to the success of this workshop. We wish to thanks the sponsors that made the 2009 edition of SWAT4LS possible: the Virtual Laboratory for e-science1 and the Netherlands Bioinformatics Centre2 (NBIC). January, 2010 M. Scott Marshall, Albert Burger, Paolo Romano, Adrian Paschke, Andrea Splendiani 1 http://www.vl-e.nl 2 http://www.nbic.nl SWAT4LS Program committee • Christopher J. O. Baker, Department of Computer Science and Applied Statistics, University of Brunswick, Canada • Pedro Barahona, Department of Informatics, New University of Lisboa, Lisboa, Portugal • Liliana Barrio-Alvers, Transinsight GmbH, Dresden, Germany • Olivier Bodenreider, National Library of Medicine, Bethesda, MD, United States of America • Matt-Mouley Bouamrane, School of Computer Science, University of Manchester, manchester, United Kingdom • Werner Ceusters, NY CoE in Bioinformatics and Life Sciences, University at Buffalo, Buffalo, NY, United States of America • Kei Cheung, Center for Medical Informatics, Yale University School of Medicine, New Haven, United States of America • Tim Clark, Massachuttes General Hospital and Harvard Medical School, Boston, United States of America • Marie-Dominique Devignes, LORIA, Vandoeuvre les Nancy, France • Olivier Dameron, INSERM U936, University of Rennes 1, France • Michel Dumontier, Carleton University, Ottawa, Ontario, Canada • Huajun Chen, Zhejiang University, China • Duncan Hull, School of Chemistry, University of Manchester, UK • C. Maria Keet, Faculty of Computer Science, Free University of Bozen-Bolzano, Bolzano, Italy • Graham Kemp, Chalmers University of Technology, Sweden • Jacob Tilman Koehler, Department of Molecular Biotechnology, Institute of Medical Biology, University of Tromsö, Tromsö, Norway • Michael Krauthammer, Department of Pathology, Yale University School of Medicine, United States of America • Martin Kuiper, Department of Pathology, Systems Biology group, Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway • Patrick Lambrix, Department of Computer and Information Science, Linköping University, Linköping, Sweden • Phillip Lord, School of Computing Science, Newcastle University, Newcastle-upon-Tyne, United Kingdom • Chris Mungall, Lawrence Berkeley National Laboratories, United States of America • Stephan Philippi, Institute for Software Technology, University of Koblenz-Landau, Koblenz, Germany • Marco Roos, Instituut voor Informatica, University of Amsterdam, The Netherlands • Alan Ruttenberg, Science Commons, Cambridge, MA, United States of America • Matthias Samwald, DERI, Galway, Ireland, and Konrad Lorenz Institute for Evolution and Cognition Research, Altenberg, Austria • Nigam Shah, Center for Biomedical Informatics Research, Stanford, United States of America • Michael Schroeder, Biotechnology Centre, TU Dresden, Dresden, Germany • Robert Stevens, School of Computer Science, University of Manchester, Manchester, United Kingdom • Tetsuro Toyoda, Genomic Sciences Center, RIKEN, Yokohama, Japan • Mark D. Wilkinson, iCAPTURE Center, St. Paul Hospital, Vancouver, Canada And the workshop co-chairs and organizers: • M. Scott Marshall, Adaptive Information Disclosure Group, University of Amsterdam, The Netherlands • Albert Burger, School of Mathematical and Computer Sciences, Heriot-Watt University, and Human Genetics Unit, Medical Research Council, Edinburgh, Scotland, United Kingdom • Adrian Paschke, Corporate Semantic Web, Freie Universitaet Berlin, Germany • Paolo Romano, Bioinformatics, National Cancer Research Institute, Genova, Italy • Andrea Splendiani, Biomathematics and Bioinformatics dept., Rothamsted Research, UK