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  <front>
    <journal-meta />
    <article-meta>
      <title-group>
        <article-title>Scientific Collaborations: Principles of WikiBridge Design</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <string-name>Éric Leclercq</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <contrib contrib-type="author">
          <string-name>Marinette Savonnet</string-name>
          <xref ref-type="aff" rid="aff0">0</xref>
        </contrib>
        <aff id="aff0">
          <label>0</label>
          <institution>University of Burgundy Le2I Laboratory - UMR 5158 B.P.</institution>
          <addr-line>47 870, 21078 Dijon Cedex -</addr-line>
          <country country="FR">France</country>
        </aff>
      </contrib-group>
      <abstract>
        <p>Semantic wikis, wikis enhanced with Semantic Web technologies, are appropriate systems for community-authored knowledge models. They are particularly suitable for scientific collaboration. This paper details the design principles of WikiBridge, a semantic wiki.</p>
      </abstract>
    </article-meta>
  </front>
  <body>
    <sec id="sec-1">
      <title>-</title>
      <p>
        1 Introduction
Collaborative environments for scientific knowledge are essential for scientists
to formalize their ideas and to develop theories collaboratively. Large
numerous corpuses created in a collaborative effort have emerged in recent years.
For example the encyclopedia Wikipedia contains human-readable articles with
texts, images which are grouped into categories and access with a full text
search engine. Despite the power of wiki, it is difficult to answer a specific
query because of the purely textual information stored. As a result, automated
tools cannot understand knowledge and thus exploit it. Semantic wikis offer
an open environment which allows to aggregate knowledge produced by
different teams involved in different research fields. It also allows interoperability
among corpuses in case of annotations defined using ontologies. Nevertheless,
representing and managing life sciences data and related knowledge require
a deep understanding of life sciences concepts. Chen and Carlis in [
        <xref ref-type="bibr" rid="ref2">2</xref>
        ] have
identified four challenging characteristics that make difficult modeling in life
sciences : 1) complexity of data (heterogeneous, incomplete, uncertain,
inconsistent, multi-dimensional); 2) domain knowledge barrier; 3) evolving
knowledge and 4) modeling skills of actors.
      </p>
      <p>Our main objective is to build a platform that allows: 1) to capture both
free and controlled data; 2) to verify that annotations have meaning in relation
to domain knowledge; 3) and to ensure a reasonable cost of developing and
maintaining.</p>
      <p>The rest of the paper is organized as follow: section 2 describes the state of
art of semantic wikis in Life Sciences, section 3 presents the design principles
of WikiBridge. Finally, section 4 concludes the paper.</p>
    </sec>
    <sec id="sec-2">
      <title>State of art</title>
      <p>Wikis are simple to use, flexible and do not impose a predefined workflow, but
with growing amount of content in wikis, it becomes increasingly difficult to
find relevant information. In traditional wiki, semantics is not explicit, but is
implicitly described by links between articles and by the context of the link
(surrounding text): wiki engine does not interpret the knowledge contained in links
graphs. A Semantic Wiki is a wiki enhanced with Semantic Web technologies
that made it an appropriate system for community-authored knowledge
models by adding machine readable semantics. Moreover, a semantic wiki supports
incremental formalization of knowledge and offers enhanced navigation and
query capabilities. We get insight below into semantic wikis for life sciences.</p>
      <p>
        A wiki page of wikipedia1 maintains a list of bioinformatics wikis and
several semantic wikis projects dedicated to Life Sciences. In Makna [
        <xref ref-type="bibr" rid="ref3 ref9">3</xref>
        ], users
can create semantic content using RDF statements referencing pre-existing
ontologies. A specific application, MannWiki, has been developed for sharing
knowledge on micro-array in Life Science domain. BOWiki [
        <xref ref-type="bibr" rid="ref5">5</xref>
        ] could be
considered as a gene function wiki that can be used to collaboratively edit biomedical
knowledge, biological information about genes and the latest scientific results.
OpenDrugWiki [
        <xref ref-type="bibr" rid="ref6">6</xref>
        ] uses a semantic wiki as a consolidation tool for integrating
heterogeneous drug data available in different documents. LabService Wiki [
        <xref ref-type="bibr" rid="ref4">4</xref>
        ]
is dedicated to the management of a production laboratory and adds workflow
capabilities to the semantic wiki engine. Brede Wiki [
        <xref ref-type="bibr" rid="ref7">7</xref>
        ] contains information
from published peer-reviewed neuroscience articles. Information in the
template forms includes for instance ontologies for brain function (i.e. cognitive
components), brain regions. Databases can be generated from templates by
only extracting the logical structures. Moreover, Boulos in [
        <xref ref-type="bibr" rid="ref1">1</xref>
        ] presents some
semantic wikis examples from health and healthcare sciences.
3
      </p>
    </sec>
    <sec id="sec-3">
      <title>WikiBridge Design principles</title>
      <p>
        WikiBridge is developed as a prototype tool to support knowledge engineers
in collaboratively formalizing knowledge. In this purpose we have extended
MediaWiki with some structural DBMS capabilities and semantic tools (see
figure 1). WikiBridge’s design principles are influenced by requirements given by
Uren et al. [
        <xref ref-type="bibr" rid="ref8">8</xref>
        ].
      </p>
      <p>WikiBridge offers an interactive WYSIWYG editor using AJAX technology
to communicate with the server backend in addition to the traditional
structured text editor (offered by MediaWiki) that supports interactive typing of
links and resources. The structured data can be managed by Semantic Forms
extension2 for MediaWiki. Documents can be in different formats such as
word files, graphic files, excel sheets, XML formats, OBO flat file.
1 http://en.wikipedia.org/wiki/Portal:Gene_Wiki/Other_Wikis
2 http://www.mediawiki.org/wiki/Extension:Semantic_Forms
Document Management System</p>
      <p>Data</p>
      <p>Source Documents</p>
      <p>Annotation Support</p>
      <p>produce
Annotation</p>
      <p>Storage
Query Engine</p>
      <p>Knowledge Engineering</p>
      <p>produce</p>
      <p>Knowledge engineer Scientists</p>
      <p>In a knowledge engineering process, it is common that non-technical
domain experts work together with experienced knowledge engineers. This means
that certain advanced functionalities can be hidden for novice users but are
available to experienced users. Thus we use Access Control List (ACL) to
describe privilege control depending on user identity and group affiliation.</p>
      <p>WikiBridge supports annotation functionalities within the same interface
as the primary data to avoid unnecessary context and application switches. In
the meantime, these annotations must be maintained on clearly separated
layers to keep integrity and traceability of the primary data. Different types of
annotations have been identified: 1) simple annotation allows to tag a subject
by describing some of its properties by a set of attribute value couples; 2)
nary relation allows to map a subject with two or more values and references
to other elements (subjects). In this case, some values properties reference
another subject; 3) recursive annotation allows to explain or clarify an attribute
by a sub-annotation. To be able to exchange data with other applications (e.g.
ontology editors, Web Services, other wikis), WikiBridge is purely based on
existing Semantic Web standards such as the Web Ontology Language OWL for
describing ontologies and W3C’s RDF for annotations. Annotations are stored
by RAP as RDF triples, separately from the original document. We explicitly
store in a database the conceptual model defining the structure of the domain
ontology; ontology is loaded from Protégé by a specific program. Information
access has been designed with taking into account some features about users.
We have thus identified an usage typology in accordance to 1) kind of usage:
reader, investigation, clarification; 2) knowledge degree of the domain: domain
specialists like biologist researchers and non specialists. Queries are expressed
in SPARQL. We consider reasoning as one of the most important
functionalities as it allows : 1) to emerge knowledge that is not explicit in the data; 2) to
check annotations, and 3) to enhance navigation and search. First order logic
constraints are checked with a Java component that interacts with Pellet and
Jena. WikiBridge extension connects to the constraint checker by the means of
a web service.
4</p>
      <p>Conclusion
In this article, we have presented WikiBridge, a feature-rich semantic wiki. The
first experiment of the use of WikiBridge3 shows many interesting possibilities
for scientific community, mainly the possibility to scientists share and
collaboratively build annotated knowledge. We have demonstrated that flexibility and
data quality required by scientific applications can be achieved by using wiki
with semantic web technologies.</p>
    </sec>
  </body>
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</article>