Laser-induced incandescence (LII) has become a common method for in-situ analysis of particle size and visualization of particle volume fractions predominantly for soot diagnostics in a wide range of applications. Besides lower signal strength due to less strongly absorbing material and lower heat-up temperatures, one of the main challenges when applying LII to non-carbon nanoparticles is the poor data base of relevant particle thermophysical properties, e.g., heat conduction, accommodation coefficients, vaporization enthalpy and high-temperature chemistry for describing particle cooling due to convection, vaporization, and other effects. In the present work the measured laser-induced emission signals from flame-synthesized iron oxide (Fe2O3) nanoparticles were evaluated in terms of particle sizing by using a modified version of the TiRe-LII model developed by Kock et al. [1].